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The map label for this gene is fps [H]

Identifier: 188527752

GI number: 188527752

Start: 973031

End: 973942

Strand: Direct

Name: fps [H]

Synonym: HPSH_04895

Alternate gene names: 188527752

Gene position: 973031-973942 (Clockwise)

Preceding gene: 188527751

Following gene: 188527753

Centisome position: 60.49

GC content: 37.72

Gene sequence:

>912_bases
ATGAATAACCCTAATTTATCCTTTTATTATAATGAGTGCGAGCGTTTTGAAAGCTTTTTAAACCACCATCATTTACACCT
TGAAAGCTTCCACCCTTATTTGGAAAAAGCCTTTTTTGAAATGGTGCTTAATGGGGGTAAAAGGTTCCGCCCTAAGCTTT
TTTTAGCCGTGCTTTGCGCGTTAGTGGGTCAAAAAGATTATTCTAGCCAGCAAACAGAATATTTTAAAATCGCTTTAAGC
ATTGAATGCTTGCACACTTATTCGCTCATCCATGACGATTTACCATGCATGGATAATGCCGCTTTAAGGAGAAACCACCC
CACTTTACACGCTAAATATGATGAAACCACAGCCGTTTTAATCGGCGATGCGCTCAACACTTACTCTTTTGAATTGCTTT
CAAATTCTTTACTAGAAAGCCATATCATTGTGGAATTGATCAAAATCTTAAGCGCTAATGGGGGGATTAAAGGCATGATC
TTAGGGCAGGCTTTGGATTGCTATTTTGAAAACACGCCCTTAAATTTAGAGCAGCTCACTTTCTTACACGAGCATAAAAC
CGCTAAATTGATTAGCGCAAGCTTGATGATGGGGTTTGTTGCAAGCGGTATTAAAGATGAAGAGCTTTTTAAATGGCTTC
AGGCTTTTGGGTTAAAAATGGGTCTTTGCTTTCAAGTGTTAGATGATATTATAGATGTTACACAAGATGAAGAAGAAAGC
GGTAAAACCACTCATTTAGACGGCGCTAAAAACAGCTTTGTGAATTTATTGGGGCTAGAAAAGGCAAGCGGTTACGCTCA
AACTTTAAAAACAGAGGTTTTAGACGATTTAAACCTACTAAAACCCGCTTATCCTTTATTGCAAGAAAATTTGAACGCAT
TATTGAACACTCTATTTAAAGGTAAGACATGA

Upstream 100 bases:

>100_bases
GATCATTAAAACAAGCGTTCTAAAAGGCCTCTTTAAAAAAGACCCTAAAACCAGAGCTGAATTTATGCAACTCTTAAAAT
CTTAGGTTATAATTCTGTGC

Downstream 100 bases:

>100_bases
AAAAAATTTTACTCACCAACGATGATGGCTACCATGCAAAAGGCATTAAAGCTTTAGAACAAGCTTTAGAAAAAATGGCA
GAAATTTATGTGGTCGCCCC

Product: geranyltranstransferase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MNNPNLSFYYNECERFESFLNHHHLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCALVGQKDYSSQQTEYFKIALS
IECLHTYSLIHDDLPCMDNAALRRNHPTLHAKYDETTAVLIGDALNTYSFELLSNSLLESHIIVELIKILSANGGIKGMI
LGQALDCYFENTPLNLEQLTFLHEHKTAKLISASLMMGFVASGIKDEELFKWLQAFGLKMGLCFQVLDDIIDVTQDEEES
GKTTHLDGAKNSFVNLLGLEKASGYAQTLKTEVLDDLNLLKPAYPLLQENLNALLNTLFKGKT

Sequences:

>Translated_303_residues
MNNPNLSFYYNECERFESFLNHHHLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCALVGQKDYSSQQTEYFKIALS
IECLHTYSLIHDDLPCMDNAALRRNHPTLHAKYDETTAVLIGDALNTYSFELLSNSLLESHIIVELIKILSANGGIKGMI
LGQALDCYFENTPLNLEQLTFLHEHKTAKLISASLMMGFVASGIKDEELFKWLQAFGLKMGLCFQVLDDIIDVTQDEEES
GKTTHLDGAKNSFVNLLGLEKASGYAQTLKTEVLDDLNLLKPAYPLLQENLNALLNTLFKGKT
>Mature_303_residues
MNNPNLSFYYNECERFESFLNHHHLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCALVGQKDYSSQQTEYFKIALS
IECLHTYSLIHDDLPCMDNAALRRNHPTLHAKYDETTAVLIGDALNTYSFELLSNSLLESHIIVELIKILSANGGIKGMI
LGQALDCYFENTPLNLEQLTFLHEHKTAKLISASLMMGFVASGIKDEELFKWLQAFGLKMGLCFQVLDDIIDVTQDEEES
GKTTHLDGAKNSFVNLLGLEKASGYAQTLKTEVLDDLNLLKPAYPLLQENLNALLNTLFKGKT

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786623, Length=254, Percent_Identity=37.4015748031496, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789578, Length=252, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17505681, Length=227, Percent_Identity=25.9911894273128, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 34272; Mature: 34272

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNPNLSFYYNECERFESFLNHHHLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCA
CCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LVGQKDYSSQQTEYFKIALSIECLHTYSLIHDDLPCMDNAALRRNHPTLHAKYDETTAVL
HHCCCCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEECCCCEEEE
IGDALNTYSFELLSNSLLESHIIVELIKILSANGGIKGMILGQALDCYFENTPLNLEQLT
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCHHHHH
FLHEHKTAKLISASLMMGFVASGIKDEELFKWLQAFGLKMGLCFQVLDDIIDVTQDEEES
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCC
GKTTHLDGAKNSFVNLLGLEKASGYAQTLKTEVLDDLNLLKPAYPLLQENLNALLNTLFK
CCEEECCCCHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GKT
CCC
>Mature Secondary Structure
MNNPNLSFYYNECERFESFLNHHHLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCA
CCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LVGQKDYSSQQTEYFKIALSIECLHTYSLIHDDLPCMDNAALRRNHPTLHAKYDETTAVL
HHCCCCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEECCCCEEEE
IGDALNTYSFELLSNSLLESHIIVELIKILSANGGIKGMILGQALDCYFENTPLNLEQLT
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCHHHHH
FLHEHKTAKLISASLMMGFVASGIKDEELFKWLQAFGLKMGLCFQVLDDIIDVTQDEEES
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCC
GKTTHLDGAKNSFVNLLGLEKASGYAQTLKTEVLDDLNLLKPAYPLLQENLNALLNTLFK
CCEEECCCCHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GKT
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9515931 [H]