Click here to switch to the map view.

The map label for this gene is pta [H]

Identifier: 188527730

GI number: 188527730

Start: 936737

End: 938293

Strand: Reverse

Name: pta [H]

Synonym: HPSH_04765

Alternate gene names: 188527730

Gene position: 938293-936737 (Counterclockwise)

Preceding gene: 188527740

Following gene: 188527729

Centisome position: 58.33

GC content: 43.16

Gene sequence:

>1557_bases
ATGCAAGGTTTGTGGATTTACCCAGAGAATACAGAAGTTTTAGGAATCGCTTGCAAGAGCCTTTTAAAAGCGCTAAAGCC
GCGCTATCAAAAAATCGCATTGTTTTCGCCCATTGATGGGGGGTGTGAGGGCTTTTTGGGGTGTGATGGCTTGAGTCCTT
TAGAGTTTCATAGCGCCATAGACAAACAAAAGGCTTTAGAGCTTGCGAGCGCTGCTCAAGAAGAGTTACTTTTTGAAACG
ATTCTCAAACGCTATGATGAATTACAAACCACGCATGACTTTGTCATTGGTTTAGGGTATGCGCCGAAGTTTTTCTTAAA
CGCTCTTTTAGATTTAAACACCACTTTAGCCAAGCATTTAAACGCTCCTATTGTGGCTGTCGCGCAAACGAGTTTAGAGC
GTTTGAAAGCCATGCATTCTCACGCTATCAAAAAAGAAGCCCCTTTCGCTGTAGGGTTGTTTGCGGGCGAAATGCTTGAA
AAACCCAATTTTTTGAGCGCGTCTCTTTGCAAGCAACGATGCGAATTAGAAGCGGATCTGATAGAAAGCGTGTTGCAAAC
AAAAAGCGAGATCACCACCCCTTTAGCCTTTCAAATGGGTTTGGAAAAAAAGGCTAAAAAACAGATTAAAAAAGTGGTTT
TACCAGAGAGCGAAGATGAAAGGATTTTAAAAGCCGCGCATCGTTTGAACGCTATGGGCGCGGTAGGATTGATTTTATTA
GGCGATAAAGAAGCCATTAATTCCCAAGCGAAAAATTTGAACTTGAATTTAGAAAATGCAGAAATCATTGATCCCAACAC
TTCTCATTATAAAGAAGAGTTCGCTAACAATTTGTATAAATTGCGAAAATCAAAGGGCTTGAGTGAGCAAGAAGCTAAGC
AATTGGTGCTCAATAAGACTTATTTTGCGACCATGCTCGTGCATTTGGGCTATGCGCATGCGATGGTTTCTGGGGTGAAT
CACACCACGGCCGACACCATTAGACCCGCTTTACAAATCATTAAAACCAAGCCCGGCGTGAGCCTGGTTTCAAGCGTGTT
TTTAATGTGTTTAGACACTCAAGTGTTAGTCTTTGGGGATTGTGCGATTATCCCTAACCCTAGCCCTAAAGAATTGGCTG
AAATCGCTATCACTTCCGCACAAAGCGCCAAGCAATTCAATATCGCGCCTAAAGTGGCCTTACTCTCTTATGCGACAGGC
GATTCCGCTCAAGGCGAAATGATAGACAAAATCAACGAAGCTGTAACCATCGCTCAACATTTAGATCCACAATTAGAAAT
TGATGGCCCCTTACAATTTGACGCTTCCATTGATAAAAGCGTAGCGAAGAAAAAAATGCCTAACAGCCAAGTGGCCGGGC
AAGCTAGCGTTTTTATTTTCCCGGATTTAAACGCTGGGAATATCGCTTATAAAGCGGTGCAACGAAGCGCTAAAGCCGTG
GCGATAGGGCCCATCTTGCAAGGTTTGAATAAGCCCATTAACGATTTGAGTAGGGGCGCTTTGGTGGAAGATATTATCAA
CACCGTTTTGATTAGCGCCCTTCAAGCGCAAGATTAA

Upstream 100 bases:

>100_bases
GTAAAAAATGCTAAAAGCATTTTACAAAATCATGGTTTCGTTTAGGTTTAATTAAATTTTGCTACAATTAAATAAAAAAC
GATAATTTACGGAGTTTTGC

Downstream 100 bases:

>100_bases
TCCACTAGGAGAAATTGATGGAAATTTTAGTTTTGAATCTGGGCAGTTCGTCTATTAAGTTTAAATTGTTTGACATGAAA
GAAAACAAGCCCTTAGCGAG

Product: phosphotransacetylase

Products: NA

Alternate protein names: Phosphotransacetylase [H]

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MQGLWIYPENTEVLGIACKSLLKALKPRYQKIALFSPIDGGCEGFLGCDGLSPLEFHSAIDKQKALELASAAQEELLFET
ILKRYDELQTTHDFVIGLGYAPKFFLNALLDLNTTLAKHLNAPIVAVAQTSLERLKAMHSHAIKKEAPFAVGLFAGEMLE
KPNFLSASLCKQRCELEADLIESVLQTKSEITTPLAFQMGLEKKAKKQIKKVVLPESEDERILKAAHRLNAMGAVGLILL
GDKEAINSQAKNLNLNLENAEIIDPNTSHYKEEFANNLYKLRKSKGLSEQEAKQLVLNKTYFATMLVHLGYAHAMVSGVN
HTTADTIRPALQIIKTKPGVSLVSSVFLMCLDTQVLVFGDCAIIPNPSPKELAEIAITSAQSAKQFNIAPKVALLSYATG
DSAQGEMIDKINEAVTIAQHLDPQLEIDGPLQFDASIDKSVAKKKMPNSQVAGQASVFIFPDLNAGNIAYKAVQRSAKAV
AIGPILQGLNKPINDLSRGALVEDIINTVLISALQAQD

Sequences:

>Translated_518_residues
MQGLWIYPENTEVLGIACKSLLKALKPRYQKIALFSPIDGGCEGFLGCDGLSPLEFHSAIDKQKALELASAAQEELLFET
ILKRYDELQTTHDFVIGLGYAPKFFLNALLDLNTTLAKHLNAPIVAVAQTSLERLKAMHSHAIKKEAPFAVGLFAGEMLE
KPNFLSASLCKQRCELEADLIESVLQTKSEITTPLAFQMGLEKKAKKQIKKVVLPESEDERILKAAHRLNAMGAVGLILL
GDKEAINSQAKNLNLNLENAEIIDPNTSHYKEEFANNLYKLRKSKGLSEQEAKQLVLNKTYFATMLVHLGYAHAMVSGVN
HTTADTIRPALQIIKTKPGVSLVSSVFLMCLDTQVLVFGDCAIIPNPSPKELAEIAITSAQSAKQFNIAPKVALLSYATG
DSAQGEMIDKINEAVTIAQHLDPQLEIDGPLQFDASIDKSVAKKKMPNSQVAGQASVFIFPDLNAGNIAYKAVQRSAKAV
AIGPILQGLNKPINDLSRGALVEDIINTVLISALQAQD
>Mature_518_residues
MQGLWIYPENTEVLGIACKSLLKALKPRYQKIALFSPIDGGCEGFLGCDGLSPLEFHSAIDKQKALELASAAQEELLFET
ILKRYDELQTTHDFVIGLGYAPKFFLNALLDLNTTLAKHLNAPIVAVAQTSLERLKAMHSHAIKKEAPFAVGLFAGEMLE
KPNFLSASLCKQRCELEADLIESVLQTKSEITTPLAFQMGLEKKAKKQIKKVVLPESEDERILKAAHRLNAMGAVGLILL
GDKEAINSQAKNLNLNLENAEIIDPNTSHYKEEFANNLYKLRKSKGLSEQEAKQLVLNKTYFATMLVHLGYAHAMVSGVN
HTTADTIRPALQIIKTKPGVSLVSSVFLMCLDTQVLVFGDCAIIPNPSPKELAEIAITSAQSAKQFNIAPKVALLSYATG
DSAQGEMIDKINEAVTIAQHLDPQLEIDGPLQFDASIDKSVAKKKMPNSQVAGQASVFIFPDLNAGNIAYKAVQRSAKAV
AIGPILQGLNKPINDLSRGALVEDIINTVLISALQAQD

Specific function: Conversion of acetate to acetyl-CoA; second step. [C]

COG id: COG0280

COG function: function code C; Phosphotransacetylase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788635, Length=344, Percent_Identity=49.1279069767442, Blast_Score=325, Evalue=4e-90,
Organism=Escherichia coli, GI1788800, Length=311, Percent_Identity=35.048231511254, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1788806, Length=326, Percent_Identity=27.6073619631902, Blast_Score=157, Evalue=2e-39,

Paralogues:

None

Copy number: 1420 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1250 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004614
- InterPro:   IPR002505 [H]

Pfam domain/function: PF01515 PTA_PTB [H]

EC number: =2.3.1.8 [H]

Molecular weight: Translated: 56334; Mature: 56334

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGLWIYPENTEVLGIACKSLLKALKPRYQKIALFSPIDGGCEGFLGCDGLSPLEFHSAI
CCCEEECCCCCCHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
DKQKALELASAAQEELLFETILKRYDELQTTHDFVIGLGYAPKFFLNALLDLNTTLAKHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHC
NAPIVAVAQTSLERLKAMHSHAIKKEAPFAVGLFAGEMLEKPNFLSASLCKQRCELEADL
CCCEEHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCCCCCHHHHHHHHHCCCHHH
IESVLQTKSEITTPLAFQMGLEKKAKKQIKKVVLPESEDERILKAAHRLNAMGAVGLILL
HHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEE
GDKEAINSQAKNLNLNLENAEIIDPNTSHYKEEFANNLYKLRKSKGLSEQEAKQLVLNKT
CCHHHHHHHHHCCEEECCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
YFATMLVHLGYAHAMVSGVNHTTADTIRPALQIIKTKPGVSLVSSVFLMCLDTQVLVFGD
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEC
CAIIPNPSPKELAEIAITSAQSAKQFNIAPKVALLSYATGDSAQGEMIDKINEAVTIAQH
EEECCCCCHHHHHHHHHHHHHCCHHCCCCCHHHEEEECCCCCCCCHHHHHHHHHHHHHHH
LDPQLEIDGPLQFDASIDKSVAKKKMPNSQVAGQASVFIFPDLNAGNIAYKAVQRSAKAV
CCCCEEECCCEEECCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCE
AIGPILQGLNKPINDLSRGALVEDIINTVLISALQAQD
EHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQGLWIYPENTEVLGIACKSLLKALKPRYQKIALFSPIDGGCEGFLGCDGLSPLEFHSAI
CCCEEECCCCCCHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
DKQKALELASAAQEELLFETILKRYDELQTTHDFVIGLGYAPKFFLNALLDLNTTLAKHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHC
NAPIVAVAQTSLERLKAMHSHAIKKEAPFAVGLFAGEMLEKPNFLSASLCKQRCELEADL
CCCEEHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCCCCCHHHHHHHHHCCCHHH
IESVLQTKSEITTPLAFQMGLEKKAKKQIKKVVLPESEDERILKAAHRLNAMGAVGLILL
HHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEE
GDKEAINSQAKNLNLNLENAEIIDPNTSHYKEEFANNLYKLRKSKGLSEQEAKQLVLNKT
CCHHHHHHHHHCCEEECCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
YFATMLVHLGYAHAMVSGVNHTTADTIRPALQIIKTKPGVSLVSSVFLMCLDTQVLVFGD
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEC
CAIIPNPSPKELAEIAITSAQSAKQFNIAPKVALLSYATGDSAQGEMIDKINEAVTIAQH
EEECCCCCHHHHHHHHHHHHHCCHHCCCCCHHHEEEECCCCCCCCHHHHHHHHHHHHHHH
LDPQLEIDGPLQFDASIDKSVAKKKMPNSQVAGQASVFIFPDLNAGNIAYKAVQRSAKAV
CCCCEEECCCEEECCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCE
AIGPILQGLNKPINDLSRGALVEDIINTVLISALQAQD
EHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]