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The map label for this gene is ackA [H]

Identifier: 188527729

GI number: 188527729

Start: 935514

End: 936719

Strand: Reverse

Name: ackA [H]

Synonym: HPSH_04760

Alternate gene names: 188527729

Gene position: 936719-935514 (Counterclockwise)

Preceding gene: 188527730

Following gene: 188527728

Centisome position: 58.23

GC content: 41.87

Gene sequence:

>1206_bases
ATGGAAATTTTAGTTTTGAATCTGGGCAGTTCGTCTATTAAGTTTAAATTGTTTGACATGAAAGAAAACAAGCCCTTAGC
GAGCGGTTTGGCCGAAAAAATCGGCGAAGAAATAGGGCAGTTGAAAATCAAATCGCATTTGCACCATAACGAGCAAGAGC
TTAAAGAAAAGCTTGTGATTAAAGATCATGCGAGCGGGCTTTTAATGATTCGTGAGAATTTGACGAAAATGGGGATCATC
AAAGATTTCAATCAAATTGACGCTATAGGGCATCGTGTGGTTCAAGGAGGGGATAAATTCCATGCCCCAATCTTAGTTAA
TGAAAAAGTCATGCAAGAAATTGGCAAGCTTTCTATTTTAGCCCCCTTGCACAACCCGGCGAATTTAGCCGGTATTGAGT
TTGTTCAAAAAGCGCACCCCCATATCCCTCAAATCGCTGTTTTTGACACCGCATTCCATGCCACTATGCCCAGTTACGCT
TACATGTATGCGTTGCCTTATGAATTGTATGAAAAGTATCAAATCCGCCGTTATGGTTTCCATGGGACTTCACACCATTA
TGTGGCTAAAGAAGCGGCGAAGTTTTTGAATACCGCTTATGAGGAATTTAACGCTATCAGTTTGCATTTAGGGAACGGCT
CAAGCGCAGCAGCCATTCAAAAGGGTAAAAGCGTGGATACTTCTATGGGGCTAACCCCTTTAGAAGGCTTGATCATGGGC
ACAAGGTGTGGGGATATTGATCCCACTGTGGTGGAATACATTGCGCAATGCGCTGATAAAAGTTTAGAAGAAGTGATGAA
AATTTTAAATTATGAAAGCGGCTTGAAAGGCATTTGTGGGGATAATGACGCCAGAAACATAGAAGCCAGAAAAGAAAAAG
GCGATAAGCAGGCCAAGCTCGCTTTTGAAATGTGCGCTTATCGCATTAAAAAGTATATTGGGGCTTACATGGCAGTCTTA
AAAAAAGTGGATGCGATTATCTTTACAGCGGGATTAGGGGAAAACTACTCGGCTTTAAGAGAGAGCGTGTGCGAAGGCTT
AGAAGATTTAGGGATCGCTTTGCACAAGCCCACGAACGACAATCCGGGCAACGGATTAGTGGATTTGAGCCAGCCTGACG
CTAAAGTTAAGGTTTTATTAATCCCTACTGATGAAGAGCTAGAAATCGCTTTACAAGCGAAAGAAATAGCAGAAAAATTA
AAATAA

Upstream 100 bases:

>100_bases
CCATTAACGATTTGAGTAGGGGCGCTTTGGTGGAAGATATTATCAACACCGTTTTGATTAGCGCCCTTCAAGCGCAAGAT
TAATCCACTAGGAGAAATTG

Downstream 100 bases:

>100_bases
AGGTTGTTTGATGAAAATGGTTCATTTTTTAGAGGGCGTTCATTTTGAAAAGCTCCACATTGAAGCGTTGAGTGAAAATT
CTTCCAATAAGGAAATGCGC

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MEILVLNLGSSSIKFKLFDMKENKPLASGLAEKIGEEIGQLKIKSHLHHNEQELKEKLVIKDHASGLLMIRENLTKMGII
KDFNQIDAIGHRVVQGGDKFHAPILVNEKVMQEIGKLSILAPLHNPANLAGIEFVQKAHPHIPQIAVFDTAFHATMPSYA
YMYALPYELYEKYQIRRYGFHGTSHHYVAKEAAKFLNTAYEEFNAISLHLGNGSSAAAIQKGKSVDTSMGLTPLEGLIMG
TRCGDIDPTVVEYIAQCADKSLEEVMKILNYESGLKGICGDNDARNIEARKEKGDKQAKLAFEMCAYRIKKYIGAYMAVL
KKVDAIIFTAGLGENYSALRESVCEGLEDLGIALHKPTNDNPGNGLVDLSQPDAKVKVLLIPTDEELEIALQAKEIAEKL
K

Sequences:

>Translated_401_residues
MEILVLNLGSSSIKFKLFDMKENKPLASGLAEKIGEEIGQLKIKSHLHHNEQELKEKLVIKDHASGLLMIRENLTKMGII
KDFNQIDAIGHRVVQGGDKFHAPILVNEKVMQEIGKLSILAPLHNPANLAGIEFVQKAHPHIPQIAVFDTAFHATMPSYA
YMYALPYELYEKYQIRRYGFHGTSHHYVAKEAAKFLNTAYEEFNAISLHLGNGSSAAAIQKGKSVDTSMGLTPLEGLIMG
TRCGDIDPTVVEYIAQCADKSLEEVMKILNYESGLKGICGDNDARNIEARKEKGDKQAKLAFEMCAYRIKKYIGAYMAVL
KKVDAIIFTAGLGENYSALRESVCEGLEDLGIALHKPTNDNPGNGLVDLSQPDAKVKVLLIPTDEELEIALQAKEIAEKL
K
>Mature_401_residues
MEILVLNLGSSSIKFKLFDMKENKPLASGLAEKIGEEIGQLKIKSHLHHNEQELKEKLVIKDHASGLLMIRENLTKMGII
KDFNQIDAIGHRVVQGGDKFHAPILVNEKVMQEIGKLSILAPLHNPANLAGIEFVQKAHPHIPQIAVFDTAFHATMPSYA
YMYALPYELYEKYQIRRYGFHGTSHHYVAKEAAKFLNTAYEEFNAISLHLGNGSSAAAIQKGKSVDTSMGLTPLEGLIMG
TRCGDIDPTVVEYIAQCADKSLEEVMKILNYESGLKGICGDNDARNIEARKEKGDKQAKLAFEMCAYRIKKYIGAYMAVL
KKVDAIIFTAGLGENYSALRESVCEGLEDLGIALHKPTNDNPGNGLVDLSQPDAKVKVLLIPTDEELEIALQAKEIAEKL
K

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=397, Percent_Identity=40.8060453400504, Blast_Score=296, Evalue=1e-81,
Organism=Escherichia coli, GI1788633, Length=402, Percent_Identity=43.2835820895522, Blast_Score=292, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 44317; Mature: 44317

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILVLNLGSSSIKFKLFDMKENKPLASGLAEKIGEEIGQLKIKSHLHHNEQELKEKLVI
CEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KDHASGLLMIRENLTKMGIIKDFNQIDAIGHRVVQGGDKFHAPILVNEKVMQEIGKLSIL
HCCCCCEEEEHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHCCEEEE
APLHNPANLAGIEFVQKAHPHIPQIAVFDTAFHATMPSYAYMYALPYELYEKYQIRRYGF
ECCCCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCC
HGTSHHYVAKEAAKFLNTAYEEFNAISLHLGNGSSAAAIQKGKSVDTSMGLTPLEGLIMG
CCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHCCCCCCCCCCCCCHHHEEEE
TRCGDIDPTVVEYIAQCADKSLEEVMKILNYESGLKGICGDNDARNIEARKEKGDKQAKL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHH
AFEMCAYRIKKYIGAYMAVLKKVDAIIFTAGLGENYSALRESVCEGLEDLGIALHKPTND
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCHHHCCEEEECCCCC
NPGNGLVDLSQPDAKVKVLLIPTDEELEIALQAKEIAEKLK
CCCCCEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEILVLNLGSSSIKFKLFDMKENKPLASGLAEKIGEEIGQLKIKSHLHHNEQELKEKLVI
CEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KDHASGLLMIRENLTKMGIIKDFNQIDAIGHRVVQGGDKFHAPILVNEKVMQEIGKLSIL
HCCCCCEEEEHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHCCEEEE
APLHNPANLAGIEFVQKAHPHIPQIAVFDTAFHATMPSYAYMYALPYELYEKYQIRRYGF
ECCCCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCC
HGTSHHYVAKEAAKFLNTAYEEFNAISLHLGNGSSAAAIQKGKSVDTSMGLTPLEGLIMG
CCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHCCCCCCCCCCCCCHHHEEEE
TRCGDIDPTVVEYIAQCADKSLEEVMKILNYESGLKGICGDNDARNIEARKEKGDKQAKL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHH
AFEMCAYRIKKYIGAYMAVLKKVDAIIFTAGLGENYSALRESVCEGLEDLGIALHKPTND
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCHHHCCEEEECCCCC
NPGNGLVDLSQPDAKVKVLLIPTDEELEIALQAKEIAEKLK
CCCCCEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]