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The map label for this gene is ruvA

Identifier: 188527709

GI number: 188527709

Start: 915726

End: 916277

Strand: Reverse

Name: ruvA

Synonym: HPSH_04655

Alternate gene names: 188527709

Gene position: 916277-915726 (Counterclockwise)

Preceding gene: 188527710

Following gene: 188527707

Centisome position: 56.96

GC content: 40.22

Gene sequence:

>552_bases
ATGATAGTGGGTTTGATAGGGGTTGTGGAAAAAATTTCTGCTTTAGAAGCGCATATAGAAGTGCAAGGGGTTGTTTATGG
GGTGCAAGTTTCTATGCGAACTTCTGCTTTGCTCCAAGCGGGCCAAAAAGCGCGTTTGAAAATCTTGCAAGTAATTAAAG
AAGATGCGCATCTTTTATACGGGTTTTTAGAAGAGAGCGAAAAAATCCTCTTTGAAAGGCTTTTAAAAATCAATGGGGTA
GGGGGGCGTATCGCTTTAGCCATTCTTTCAAGCTTTTCGCCGAATGAATTTGAAAGCATTATCGCCACTAAAGAAGTCAA
AAGACTCCAGCAAGTCCCAGGCATTGGCAAAAAGCTCGCTGATAAGATCATGGTGGATTTGATTGGTTTTTTCATTCAAG
ATGAAACAAAACCCATGCATAATGAAGTCTTTTTAGCCCTAGAGAGTTTGGGTTTTAAAAGCGCTGAAATCAATAAAGTT
TTAAAAACCCTAAAACCCCATCTCAGCACCGAAGCAGCGATTAAAGAAGCCTTACAACAACTGCGCTCTTAA

Upstream 100 bases:

>100_bases
CCATAATGAAAGCGTGAATGTGATCTATGAAGATCATAAAATCAAAAAAGTCCCTAAAAGCGCCATAAAAGGCTAGAGCG
AGAAATAAAAAAGGGATAAA

Downstream 100 bases:

>100_bases
AAAGGTTTTTTTAGTATTCCATTACTAAAAACCTAGCAAGCAATTAGAACTAAGCGCTAAAAACTCCCAATTCACCAACA
ACACGCTTAAAATCATTGAA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MIVGLIGVVEKISALEAHIEVQGVVYGVQVSMRTSALLQAGQKARLKILQVIKEDAHLLYGFLEESEKILFERLLKINGV
GGRIALAILSSFSPNEFESIIATKEVKRLQQVPGIGKKLADKIMVDLIGFFIQDETKPMHNEVFLALESLGFKSAEINKV
LKTLKPHLSTEAAIKEALQQLRS

Sequences:

>Translated_183_residues
MIVGLIGVVEKISALEAHIEVQGVVYGVQVSMRTSALLQAGQKARLKILQVIKEDAHLLYGFLEESEKILFERLLKINGV
GGRIALAILSSFSPNEFESIIATKEVKRLQQVPGIGKKLADKIMVDLIGFFIQDETKPMHNEVFLALESLGFKSAEINKV
LKTLKPHLSTEAAIKEALQQLRS
>Mature_183_residues
MIVGLIGVVEKISALEAHIEVQGVVYGVQVSMRTSALLQAGQKARLKILQVIKEDAHLLYGFLEESEKILFERLLKINGV
GGRIALAILSSFSPNEFESIIATKEVKRLQQVPGIGKKLADKIMVDLIGFFIQDETKPMHNEVFLALESLGFKSAEINKV
LKTLKPHLSTEAAIKEALQQLRS

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=187, Percent_Identity=36.8983957219251, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 20204; Mature: 20204

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGLIGVVEKISALEAHIEVQGVVYGVQVSMRTSALLQAGQKARLKILQVIKEDAHLLY
CEEHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GFLEESEKILFERLLKINGVGGRIALAILSSFSPNEFESIIATKEVKRLQQVPGIGKKLA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
DKIMVDLIGFFIQDETKPMHNEVFLALESLGFKSAEINKVLKTLKPHLSTEAAIKEALQQ
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
LRS
HCC
>Mature Secondary Structure
MIVGLIGVVEKISALEAHIEVQGVVYGVQVSMRTSALLQAGQKARLKILQVIKEDAHLLY
CEEHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GFLEESEKILFERLLKINGVGGRIALAILSSFSPNEFESIIATKEVKRLQQVPGIGKKLA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
DKIMVDLIGFFIQDETKPMHNEVFLALESLGFKSAEINKVLKTLKPHLSTEAAIKEALQQ
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
LRS
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA