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The map label for this gene is pgbA [H]

Identifier: 188527655

GI number: 188527655

Start: 856784

End: 858091

Strand: Reverse

Name: pgbA [H]

Synonym: HPSH_04385

Alternate gene names: 188527655

Gene position: 858091-856784 (Counterclockwise)

Preceding gene: 188527656

Following gene: 188527654

Centisome position: 53.35

GC content: 37.84

Gene sequence:

>1308_bases
ATGTTAAGGCTTTTGATAGGACTTCTTTTAATGAGTTTTATAAGCTTGCAATCAGCCTCTTGGCAAGAACCCTTAAGAGT
GAGTGTAGAATTTGTGGATTTGCCTAAAAAAATCATTCGTTTTCCTGCTCATGATTTGCAAGTGGGGGAGTTTGGTTTTG
TCGTTACTAAACTTTCAGATTATGAAATCGTTAATTCTGAAGTGGTTATTATTGCCGTTGAAAATGGTGTCGCAACGGCT
AAATTCAGAGCGTTTGAGTCTATGAAACAAAGCCATTTACCCACTCCAAGAATGGTCGCTAGAAAGGGTGATTTGGTCTA
TTTTAGGCAATTCAATAACCAAGCGTTTTTAATCGCTCCTAATGATGAAATCTATGAGCAAATCAGAGCGACTAACACCG
ATATTAATTTTATCAGTTCTGATTTGCTGGTTACTTTTTTGAACGGGTTTGACCCAAAAATCGCCAATTTAAGAAAAGCG
TGCAATGTTTATAGTGTGGGGGTGATTTATATTGTAACCACGAACACGCTCAATATTTTAAGCTGTGAGAGTTTTGAAAT
TTTAGAAAAAAGAGAGCTGGATACAAGCGGCGTTACTAAAACTTCTACGCCGTTTTTTTCTAGGGTTGAGGGCATTGATG
CAGGCACGCTAGGGAAAGTTTTTTCAGGCAGTCAATCTAAAAATTACTTCGCTTACTATGACGCTTTAGTGAAGAAAGAA
AAACGCAAAGAAGTAAGGATTAAAAAGCAAGAAGAAAGGATTGACTCTAGAGAAATTAAACGAGAAATCAAGCAAGAAGC
CATTAAAGAGCCTAAAAAAGCCAATCAAGGCACAGAAAACGCTCCTACTTTAGAAGAGAAAAACTACCAAAAAGCAGAGC
GCAAACTTGATGCTAAAGAAGAAAGGCGTCGTTTAAGAGATGAAAGGAAAAAAACCAAAGCCACCAAAAAGGCTATGGAA
TTTGAAGAAAGAGAAAAAGCGCATGATGAAAGAGATGAGAGAGAAACTGAAGAAAGGAGGAAGGCTCTAGGCATGGATCA
AGGCAATGAAAAAGTCAATGCCAAAGAAAATGAGCAAGAAATCAAGCAAGAAGCCACTAAAGAGCCAAGTAACGAAAATA
ACGCTACCCAACAAGGCGAAAATAAACCAAATTCTAAAGAAGAAAAACGCCGCTTGAAAGAAGAAAAGAAAAAAGCCAAA
GCCGAACAAAGAGCGAGAGAATTTGAACAAAGAGCCAAAGAGCATCAAGAAAGAGATGAAAAAGAGCTTGAAGAGCGAAG
AAAGGCGCTAGAAGCGGGTAAAAAATAA

Upstream 100 bases:

>100_bases
CTTGATTTTATAATGGATTTTCAATACGCTAAAACCACCGGATTGTCTTTAGCCATTTTATGGCATTTAAAAAAGTTTAA
AAATGTTTAAAAGGAATTGT

Downstream 100 bases:

>100_bases
CATGTTAGAGAAACAACACATCCAATATTTTAAAAACCTGGTAGGGGGAGAGGATTTTTTCACTGATTTAGCGCATTTGA
ACGCTTATTGCTATGACGCT

Product: plasminogen binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MLRLLIGLLLMSFISLQSASWQEPLRVSVEFVDLPKKIIRFPAHDLQVGEFGFVVTKLSDYEIVNSEVVIIAVENGVATA
KFRAFESMKQSHLPTPRMVARKGDLVYFRQFNNQAFLIAPNDEIYEQIRATNTDINFISSDLLVTFLNGFDPKIANLRKA
CNVYSVGVIYIVTTNTLNILSCESFEILEKRELDTSGVTKTSTPFFSRVEGIDAGTLGKVFSGSQSKNYFAYYDALVKKE
KRKEVRIKKQEERIDSREIKREIKQEAIKEPKKANQGTENAPTLEEKNYQKAERKLDAKEERRRLRDERKKTKATKKAME
FEEREKAHDERDERETEERRKALGMDQGNEKVNAKENEQEIKQEATKEPSNENNATQQGENKPNSKEEKRRLKEEKKKAK
AEQRAREFEQRAKEHQERDEKELEERRKALEAGKK

Sequences:

>Translated_435_residues
MLRLLIGLLLMSFISLQSASWQEPLRVSVEFVDLPKKIIRFPAHDLQVGEFGFVVTKLSDYEIVNSEVVIIAVENGVATA
KFRAFESMKQSHLPTPRMVARKGDLVYFRQFNNQAFLIAPNDEIYEQIRATNTDINFISSDLLVTFLNGFDPKIANLRKA
CNVYSVGVIYIVTTNTLNILSCESFEILEKRELDTSGVTKTSTPFFSRVEGIDAGTLGKVFSGSQSKNYFAYYDALVKKE
KRKEVRIKKQEERIDSREIKREIKQEAIKEPKKANQGTENAPTLEEKNYQKAERKLDAKEERRRLRDERKKTKATKKAME
FEEREKAHDERDERETEERRKALGMDQGNEKVNAKENEQEIKQEATKEPSNENNATQQGENKPNSKEEKRRLKEEKKKAK
AEQRAREFEQRAKEHQERDEKELEERRKALEAGKK
>Mature_435_residues
MLRLLIGLLLMSFISLQSASWQEPLRVSVEFVDLPKKIIRFPAHDLQVGEFGFVVTKLSDYEIVNSEVVIIAVENGVATA
KFRAFESMKQSHLPTPRMVARKGDLVYFRQFNNQAFLIAPNDEIYEQIRATNTDINFISSDLLVTFLNGFDPKIANLRKA
CNVYSVGVIYIVTTNTLNILSCESFEILEKRELDTSGVTKTSTPFFSRVEGIDAGTLGKVFSGSQSKNYFAYYDALVKKE
KRKEVRIKKQEERIDSREIKREIKQEAIKEPKKANQGTENAPTLEEKNYQKAERKLDAKEERRRLRDERKKTKATKKAME
FEEREKAHDERDERETEERRKALGMDQGNEKVNAKENEQEIKQEATKEPSNENNATQQGENKPNSKEEKRRLKEEKKKAK
AEQRAREFEQRAKEHQERDEKELEERRKALEAGKK

Specific function: Binds plasminogen, specifically, and in a concentration and lysine-dependent manner. Plasminogen is the precursor of plasmin, a serine protease that cleaves fibrin, fibronectin, laminin and vitronectin. Acquisition of plasminogen/plasmin could enable H.py

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell surface (Probable). Note=The plasminogen-binding region is localized on the surface the bacterium (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50492; Mature: 50492

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRLLIGLLLMSFISLQSASWQEPLRVSVEFVDLPKKIIRFPAHDLQVGEFGFVVTKLSD
CHHHHHHHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHCCCCCCCCCCHHEEEEECCC
YEIVNSEVVIIAVENGVATAKFRAFESMKQSHLPTPRMVARKGDLVYFRQFNNQAFLIAP
CEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEEECCCCEEEECC
NDEIYEQIRATNTDINFISSDLLVTFLNGFDPKIANLRKACNVYSVGVIYIVTTNTLNIL
CHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEEEEEECCEEEE
SCESFEILEKRELDTSGVTKTSTPFFSRVEGIDAGTLGKVFSGSQSKNYFAYYDALVKKE
ECCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHH
KRKEVRIKKQEERIDSREIKREIKQEAIKEPKKANQGTENAPTLEEKNYQKAERKLDAKE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHCCHHH
ERRRLRDERKKTKATKKAMEFEEREKAHDERDERETEERRKALGMDQGNEKVNAKENEQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
IKQEATKEPSNENNATQQGENKPNSKEEKRRLKEEKKKAKAEQRAREFEQRAKEHQERDE
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KELEERRKALEAGKK
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MLRLLIGLLLMSFISLQSASWQEPLRVSVEFVDLPKKIIRFPAHDLQVGEFGFVVTKLSD
CHHHHHHHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHCCCCCCCCCCHHEEEEECCC
YEIVNSEVVIIAVENGVATAKFRAFESMKQSHLPTPRMVARKGDLVYFRQFNNQAFLIAP
CEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEEECCCCEEEECC
NDEIYEQIRATNTDINFISSDLLVTFLNGFDPKIANLRKACNVYSVGVIYIVTTNTLNIL
CHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEEEEEECCEEEE
SCESFEILEKRELDTSGVTKTSTPFFSRVEGIDAGTLGKVFSGSQSKNYFAYYDALVKKE
ECCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHH
KRKEVRIKKQEERIDSREIKREIKQEAIKEPKKANQGTENAPTLEEKNYQKAERKLDAKE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHCCHHH
ERRRLRDERKKTKATKKAMEFEEREKAHDERDERETEERRKALGMDQGNEKVNAKENEQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
IKQEATKEPSNENNATQQGENKPNSKEEKRRLKEEKKKAKAEQRAREFEQRAKEHQERDE
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KELEERRKALEAGKK
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]