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The map label for this gene is nudK [H]

Identifier: 188527656

GI number: 188527656

Start: 858102

End: 858740

Strand: Reverse

Name: nudK [H]

Synonym: HPSH_04390

Alternate gene names: 188527656

Gene position: 858740-858102 (Counterclockwise)

Preceding gene: 188527657

Following gene: 188527655

Centisome position: 53.39

GC content: 35.05

Gene sequence:

>639_bases
ATGTCTTATTTTAAGAATGCTTTCAATCAAAAATCTTTAATAGATGATTCTAGTGTGTATTTAGAGTCTTGTTCTAGCTC
TAATTTCATAGAATTAAAACGCATGCATTATAATGAAGAGAATACTAAGAAAACATGGGATATTATTAAGTCTTTAGACA
GCGTGGCGGTTTTACTCTATGAAAAAGAATCCGATTGTTTTGTGATTGTGAAACAATTCCGCCCAGCCATTTATGCACGC
CATTTTCATTTTAAGTGTGATCAAGATCAAAATATTGACGGATACACTTATGAATTGTGCGCAGGGCTTGTGGATAAAGC
TAATAAGAGTTTAGAAGAAATCGCTTGCGAAGAAGTGCTAGAAGAATGCGGTTATCAGATCAGCCCTAAAAATTTAGAAA
CCATAGGCCAATTTTATAGCGCAACCGGCTTGAGTGGGAGTTTGCAAACGCTCTATTACGCTGAAGTGTGCGCGCATTTG
AAAGTTTCAAAGGGTGGGGGGATTGATACAGAAAAGATTGAAGTGCTGTTTTTAAAGCGATCAAAAGCTCTTGATTTTAT
AATGGATTTTCAATACGCTAAAACCACCGGATTGTCTTTAGCCATTTTATGGCATTTAAAAAAGTTTAAAAATGTTTAA

Upstream 100 bases:

>100_bases
TTTTTTTAGAAAAAGCTCAGCATTCTAAGCAAAAATTAGAAGAACTTCTTAAAACCCATTCTTTTGAAAAAAATTCATTT
TATCTTTTAGAGGGTTTTTA

Downstream 100 bases:

>100_bases
AAGGAATTGTATGTTAAGGCTTTTGATAGGACTTCTTTTAATGAGTTTTATAAGCTTGCAATCAGCCTCTTGGCAAGAAC
CCTTAAGAGTGAGTGTAGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSYFKNAFNQKSLIDDSSVYLESCSSSNFIELKRMHYNEENTKKTWDIIKSLDSVAVLLYEKESDCFVIVKQFRPAIYAR
HFHFKCDQDQNIDGYTYELCAGLVDKANKSLEEIACEEVLEECGYQISPKNLETIGQFYSATGLSGSLQTLYYAEVCAHL
KVSKGGGIDTEKIEVLFLKRSKALDFIMDFQYAKTTGLSLAILWHLKKFKNV

Sequences:

>Translated_212_residues
MSYFKNAFNQKSLIDDSSVYLESCSSSNFIELKRMHYNEENTKKTWDIIKSLDSVAVLLYEKESDCFVIVKQFRPAIYAR
HFHFKCDQDQNIDGYTYELCAGLVDKANKSLEEIACEEVLEECGYQISPKNLETIGQFYSATGLSGSLQTLYYAEVCAHL
KVSKGGGIDTEKIEVLFLKRSKALDFIMDFQYAKTTGLSLAILWHLKKFKNV
>Mature_211_residues
SYFKNAFNQKSLIDDSSVYLESCSSSNFIELKRMHYNEENTKKTWDIIKSLDSVAVLLYEKESDCFVIVKQFRPAIYARH
FHFKCDQDQNIDGYTYELCAGLVDKANKSLEEIACEEVLEECGYQISPKNLETIGQFYSATGLSGSLQTLYYAEVCAHLK
VSKGGGIDTEKIEVLFLKRSKALDFIMDFQYAKTTGLSLAILWHLKKFKNV

Specific function: Catalyzes the hydrolysis of GDP-mannose [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI37594467, Length=203, Percent_Identity=38.9162561576355, Blast_Score=151, Evalue=4e-37,
Organism=Escherichia coli, GI1788810, Length=169, Percent_Identity=28.9940828402367, Blast_Score=61, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17558808, Length=145, Percent_Identity=38.6206896551724, Blast_Score=103, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24650557, Length=197, Percent_Identity=39.5939086294416, Blast_Score=127, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 24278; Mature: 24147

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYFKNAFNQKSLIDDSSVYLESCSSSNFIELKRMHYNEENTKKTWDIIKSLDSVAVLLY
CCHHHHHCCCCCCCCCHHHHHHHCCCCCCEEHHHHHCCCCCHHHHHHHHHHHHHEEEEEE
EKESDCFVIVKQFRPAIYARHFHFKCDQDQNIDGYTYELCAGLVDKANKSLEEIACEEVL
ECCCCEEEEHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EECGYQISPKNLETIGQFYSATGLSGSLQTLYYAEVCAHLKVSKGGGIDTEKIEVLFLKR
HHCCCEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEECCCCCCCHHHEEEEEEEC
SKALDFIMDFQYAKTTGLSLAILWHLKKFKNV
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SYFKNAFNQKSLIDDSSVYLESCSSSNFIELKRMHYNEENTKKTWDIIKSLDSVAVLLY
CHHHHHCCCCCCCCCHHHHHHHCCCCCCEEHHHHHCCCCCHHHHHHHHHHHHHEEEEEE
EKESDCFVIVKQFRPAIYARHFHFKCDQDQNIDGYTYELCAGLVDKANKSLEEIACEEVL
ECCCCEEEEHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EECGYQISPKNLETIGQFYSATGLSGSLQTLYYAEVCAHLKVSKGGGIDTEKIEVLFLKR
HHCCCEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEECCCCCCCHHHEEEEEEEC
SKALDFIMDFQYAKTTGLSLAILWHLKKFKNV
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA