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The map label for this gene is dapL [H]

Identifier: 188527526

GI number: 188527526

Start: 719044

End: 720171

Strand: Direct

Name: dapL [H]

Synonym: HPSH_03740

Alternate gene names: 188527526

Gene position: 719044-720171 (Clockwise)

Preceding gene: 188527521

Following gene: 188527527

Centisome position: 44.7

GC content: 39.72

Gene sequence:

>1128_bases
ATGACCTTTGAGCCTTATCCTTTTGAACGATTAAGAGCCTTGTTTAAAGAAATCACCCCTAAAAAAAAGGGGCTAGATTT
AGGCATCGGCGAGCCACGATTTGAAACGCCCAAATTCATTCAAGACGCTCTTAAAAGCCACACCCATTCGCTCAATATCT
ACCCTAAAAGCGCGTTTGAAGAGAGTTTGAGGGAGGCTCAAAGAGGTTTTTTTAAACGCCGTTTTAAAATAGAATTGAAA
GAAAACGAATTAATCTCCACGCTAGGATCTAGGGAAGTGTTATTCAATTTCCCTAGCTTTGTTTTATTTGATTATCAAAA
CCCCACTATCGCCTACCCTAACCCCTTTTATCAAATTTATGAAGGATCAGCCCAATTTTCTAGAGCCAAAAGCCTTTTAA
TGCCCTTAACTAAAGAAAACGATTTCACGCCAAGCTTGAATGAAAAAGAGTTGCAAGAAGTGGATTTAGTGATCTTAAAT
TCCCCCAACAACCCCACCGGAAGAACCCTTTCTTTAGAAGAGCTGATTAGTTGGGTCAAACTCGCTTTAAAACATGATTT
TATTTTAATCAATGATGAATGTTACAGCGAAATTTATGAAAATACGCCTCCCCCTTCGCTTTTAGAAGCTTGCATGCTTA
TTGGTAATGAAGCGTTTAAAAATGTTTTGGTTATCCATTCGCTCTCCAAACGCTCTAGCGCTCCAGGGCTAAGGAGTGGC
TTTATCGCTGGGGATAGCAGCATTTTAGAAAAATACAAAGCGTTTCGCACCTATTTAGGCTATACGAGCGCTAATGCGAT
CCAAAAGGCTAGTGAAATGGCTTGGCTAGATGATGCGCATGCAGAATTTTTCCGCAATATTTATGCGAATAATTTGAAAC
TGGCGCGAAAAATCTTTAAAGACACGCTCATTTATCCTTATAGTTTTTATGTGTATCTGCCCGTTCAAAACGGCGAAAAT
TTTGCCAAAACGCTTTATCAAAACGAAGGCATTATCACTTTACCGGCTTTGTATTTGGGGCGTAATCACATCGGCGCTGA
TTGCGTGCGTTTAGCCCTTGTCTATGACACCCCCCTTTTAGAAAAGCCTTTAGAAATCATAGAAACTTATCGAGAAAATC
ATGCTTGA

Upstream 100 bases:

>100_bases
AATTCTCACTCGCTATTATACTCTTTCTTAGTGGTTTCACACCATAACGCTTAAATTTTAGGTAAGATTAACTATTCCAT
TTTAAGATTAAAGTAGCCCT

Downstream 100 bases:

>100_bases
AACCCCAAAAGTTTTACTCAAAAACCTGCAAGATTGCAAAATCCATTTTATCGGTATAGGGGGGATTGGCATTTCAGGCT
TAGCCAAATACCTTAAAGCG

Product: hypothetical protein

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTFEPYPFERLRALFKEITPKKKGLDLGIGEPRFETPKFIQDALKSHTHSLNIYPKSAFEESLREAQRGFFKRRFKIELK
ENELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIYEGSAQFSRAKSLLMPLTKENDFTPSLNEKELQEVDLVILN
SPNNPTGRTLSLEELISWVKLALKHDFILINDECYSEIYENTPPPSLLEACMLIGNEAFKNVLVIHSLSKRSSAPGLRSG
FIAGDSSILEKYKAFRTYLGYTSANAIQKASEMAWLDDAHAEFFRNIYANNLKLARKIFKDTLIYPYSFYVYLPVQNGEN
FAKTLYQNEGIITLPALYLGRNHIGADCVRLALVYDTPLLEKPLEIIETYRENHA

Sequences:

>Translated_375_residues
MTFEPYPFERLRALFKEITPKKKGLDLGIGEPRFETPKFIQDALKSHTHSLNIYPKSAFEESLREAQRGFFKRRFKIELK
ENELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIYEGSAQFSRAKSLLMPLTKENDFTPSLNEKELQEVDLVILN
SPNNPTGRTLSLEELISWVKLALKHDFILINDECYSEIYENTPPPSLLEACMLIGNEAFKNVLVIHSLSKRSSAPGLRSG
FIAGDSSILEKYKAFRTYLGYTSANAIQKASEMAWLDDAHAEFFRNIYANNLKLARKIFKDTLIYPYSFYVYLPVQNGEN
FAKTLYQNEGIITLPALYLGRNHIGADCVRLALVYDTPLLEKPLEIIETYRENHA
>Mature_374_residues
TFEPYPFERLRALFKEITPKKKGLDLGIGEPRFETPKFIQDALKSHTHSLNIYPKSAFEESLREAQRGFFKRRFKIELKE
NELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIYEGSAQFSRAKSLLMPLTKENDFTPSLNEKELQEVDLVILNS
PNNPTGRTLSLEELISWVKLALKHDFILINDECYSEIYENTPPPSLLEACMLIGNEAFKNVLVIHSLSKRSSAPGLRSGF
IAGDSSILEKYKAFRTYLGYTSANAIQKASEMAWLDDAHAEFFRNIYANNLKLARKIFKDTLIYPYSFYVYLPVQNGENF
AKTLYQNEGIITLPALYLGRNHIGADCVRLALVYDTPLLEKPLEIIETYRENHA

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=282, Percent_Identity=25.531914893617, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI56713254, Length=282, Percent_Identity=25.531914893617, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788722, Length=367, Percent_Identity=25.8855585831063, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=292, Percent_Identity=22.6027397260274, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=292, Percent_Identity=22.6027397260274, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567369, Length=285, Percent_Identity=23.5087719298246, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=303, Percent_Identity=24.0924092409241, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43108; Mature: 42977

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS01037 SBP_BACTERIAL_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFEPYPFERLRALFKEITPKKKGLDLGIGEPRFETPKFIQDALKSHTHSLNIYPKSAFE
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCHHHHH
ESLREAQRGFFKRRFKIELKENELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIY
HHHHHHHHHHHHHHEEEEECHHHHHHHCCCCCEEEECCCEEEEECCCCEEECCCCCHHHH
EGSAQFSRAKSLLMPLTKENDFTPSLNEKELQEVDLVILNSPNNPTGRTLSLEELISWVK
CCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHEEEEEEECCCCCCCCEEEHHHHHHHHH
LALKHDFILINDECYSEIYENTPPPSLLEACMLIGNEAFKNVLVIHSLSKRSSAPGLRSG
HHHHCCEEEECHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHEEEHHHCCCCCCCCCC
FIAGDSSILEKYKAFRTYLGYTSANAIQKASEMAWLDDAHAEFFRNIYANNLKLARKIFK
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTLIYPYSFYVYLPVQNGENFAKTLYQNEGIITLPALYLGRNHIGADCVRLALVYDTPLL
HHHCCCEEEEEEEEECCCCHHHHHHHCCCCEEEEHHHHHCCCCCCHHHHHHHHHHCCCHH
EKPLEIIETYRENHA
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
TFEPYPFERLRALFKEITPKKKGLDLGIGEPRFETPKFIQDALKSHTHSLNIYPKSAFE
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCHHHHH
ESLREAQRGFFKRRFKIELKENELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIY
HHHHHHHHHHHHHHEEEEECHHHHHHHCCCCCEEEECCCEEEEECCCCEEECCCCCHHHH
EGSAQFSRAKSLLMPLTKENDFTPSLNEKELQEVDLVILNSPNNPTGRTLSLEELISWVK
CCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHEEEEEEECCCCCCCCEEEHHHHHHHHH
LALKHDFILINDECYSEIYENTPPPSLLEACMLIGNEAFKNVLVIHSLSKRSSAPGLRSG
HHHHCCEEEECHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHEEEHHHCCCCCCCCCC
FIAGDSSILEKYKAFRTYLGYTSANAIQKASEMAWLDDAHAEFFRNIYANNLKLARKIFK
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTLIYPYSFYVYLPVQNGENFAKTLYQNEGIITLPALYLGRNHIGADCVRLALVYDTPLL
HHHCCCEEEEEEEEECCCCHHHHHHHCCCCEEEEHHHHHCCCCCCHHHHHHHHHHCCCHH
EKPLEIIETYRENHA
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA