| Definition | Helicobacter pylori Shi470, complete genome. |
|---|---|
| Accession | NC_010698 |
| Length | 1,608,548 |
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The map label for this gene is murC
Identifier: 188527527
GI number: 188527527
Start: 720164
End: 721513
Strand: Direct
Name: murC
Synonym: HPSH_03745
Alternate gene names: 188527527
Gene position: 720164-721513 (Clockwise)
Preceding gene: 188527526
Following gene: 188527528
Centisome position: 44.77
GC content: 38.3
Gene sequence:
>1350_bases ATGCTTGAAACCCCAAAAGTTTTACTCAAAAACCTGCAAGATTGCAAAATCCATTTTATCGGTATAGGGGGGATTGGCAT TTCAGGCTTAGCCAAATACCTTAAAGCGCAAGGGGCTACAATCAGCGGCTCTGATATTGCCATAAGCCCCAGCGTTAAGT ATTTGAAAGCTTTAGGCGTAGAAATCAATATCCCGCATGATCCAAAAGCGATTAAAAATCAAGATGCCATCATCCATTCA GCCATTATTAAAGAAGACAATACAGAAATACAAAGGGCTAAGGAATTAAAAATCCCTATTTTATCTCGTAAAGACGCTTT GTATTCTATCCTTAAAGACAAGCGCGTTTTTAGCGTGTGCGGGGCCCATGGAAAAAGCAGTATCACCGCCATGTTAAGCG CGATTTTCCCCTTTTTTGGAGCGATTATTGGGGCGCATTCTAAAGAGTTTGATTCCAATGTGCGAGAAAGCGCGAATGAT AGCTTGGTTTTTGAAGCCGATGAGAGCGATTCAAGTTTTTTATTTTCTAACCCTTATGCCGCGATTGTGCCTAACACAGA GCCAGAACATTTGGAGCATTATGACCACAATTTAGAGCGTTTTTTCTTCGCTTATGAATATTTTTTAGACCATGCTCAAA AAAGAGTGATCTATAAAGAAGATCCTTTTTTAAAAAACTATTCTAAAGACGCTATTGTTTTAGAAAAAAAAGACATTCGC AATATCCAATACATTTTAAAAGACGGCGAGCCTCACACTTCATTTGAATTGAAAGATTTGGGGGCTTTTTTGGTGTGGGG GTTAGGCGAACATAACGCCACGAATGCGAGTTTGGCGATTTTAAGCGCTTTAGATGAATTGGATTTAGAAGAAATTAGAA ATAATTTATTGAATTTCAAAGGCATTAAAAAACGCTTTGACATTTTGCAAAAAAACGCGCTCATCCTCATTGATGATTAC GCCCACCACCCCACTGAAATCAGCGCCACTTTAAAAAGCGCTAGGATTTATGCTAACTTACTGAACACGCAAGAAAAGAT TGTAGTGATCTGGCAAGCGCACAAATATTCTCGCTTAATGGATAATTTAGAAGAATTTAAAAAATGTTTTTTAGAGCATT GCGACAGGTTGATCATTTTACCCGTTTATAGCGCGAGTGAAGTTAAAAGAGATATTGATTTGAAAGCCCATTTTAAGCAT TATAACCCCACCTTTATAGACAGGGTGCGTAAAAAGGGGGATTTTTTAGAGCTCTTAGTCAATGATAATGTGGTAGAAAC GATCCAAAAAGGCTTTGTGATAGGCTTTGGAGCAGGGGATATTACCTATCAATTGAGAGGCGAAATGTAA
Upstream 100 bases:
>100_bases CGTAATCACATCGGCGCTGATTGCGTGCGTTTAGCCCTTGTCTATGACACCCCCCTTTTAGAAAAGCCTTTAGAAATCAT AGAAACTTATCGAGAAAATC
Downstream 100 bases:
>100_bases TGGGTGCAGCGGTTGTTTTATTTTTAACGCTGGTTTTATTGTTTTTAGTTTTAAGGGATTTTGGTTTAGCAAGCCCTAAA CAAAAACTTGTAGCTTTTTT
Product: UDP-N-acetylmuramate--L-alanine ligase
Products: NA
Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]
Number of amino acids: Translated: 449; Mature: 449
Protein sequence:
>449_residues MLETPKVLLKNLQDCKIHFIGIGGIGISGLAKYLKAQGATISGSDIAISPSVKYLKALGVEINIPHDPKAIKNQDAIIHS AIIKEDNTEIQRAKELKIPILSRKDALYSILKDKRVFSVCGAHGKSSITAMLSAIFPFFGAIIGAHSKEFDSNVRESAND SLVFEADESDSSFLFSNPYAAIVPNTEPEHLEHYDHNLERFFFAYEYFLDHAQKRVIYKEDPFLKNYSKDAIVLEKKDIR NIQYILKDGEPHTSFELKDLGAFLVWGLGEHNATNASLAILSALDELDLEEIRNNLLNFKGIKKRFDILQKNALILIDDY AHHPTEISATLKSARIYANLLNTQEKIVVIWQAHKYSRLMDNLEEFKKCFLEHCDRLIILPVYSASEVKRDIDLKAHFKH YNPTFIDRVRKKGDFLELLVNDNVVETIQKGFVIGFGAGDITYQLRGEM
Sequences:
>Translated_449_residues MLETPKVLLKNLQDCKIHFIGIGGIGISGLAKYLKAQGATISGSDIAISPSVKYLKALGVEINIPHDPKAIKNQDAIIHS AIIKEDNTEIQRAKELKIPILSRKDALYSILKDKRVFSVCGAHGKSSITAMLSAIFPFFGAIIGAHSKEFDSNVRESAND SLVFEADESDSSFLFSNPYAAIVPNTEPEHLEHYDHNLERFFFAYEYFLDHAQKRVIYKEDPFLKNYSKDAIVLEKKDIR NIQYILKDGEPHTSFELKDLGAFLVWGLGEHNATNASLAILSALDELDLEEIRNNLLNFKGIKKRFDILQKNALILIDDY AHHPTEISATLKSARIYANLLNTQEKIVVIWQAHKYSRLMDNLEEFKKCFLEHCDRLIILPVYSASEVKRDIDLKAHFKH YNPTFIDRVRKKGDFLELLVNDNVVETIQKGFVIGFGAGDITYQLRGEM >Mature_449_residues MLETPKVLLKNLQDCKIHFIGIGGIGISGLAKYLKAQGATISGSDIAISPSVKYLKALGVEINIPHDPKAIKNQDAIIHS AIIKEDNTEIQRAKELKIPILSRKDALYSILKDKRVFSVCGAHGKSSITAMLSAIFPFFGAIIGAHSKEFDSNVRESAND SLVFEADESDSSFLFSNPYAAIVPNTEPEHLEHYDHNLERFFFAYEYFLDHAQKRVIYKEDPFLKNYSKDAIVLEKKDIR NIQYILKDGEPHTSFELKDLGAFLVWGLGEHNATNASLAILSALDELDLEEIRNNLLNFKGIKKRFDILQKNALILIDDY AHHPTEISATLKSARIYANLLNTQEKIVVIWQAHKYSRLMDNLEEFKKCFLEHCDRLIILPVYSASEVKRDIDLKAHFKH YNPTFIDRVRKKGDFLELLVNDNVVETIQKGFVIGFGAGDITYQLRGEM
Specific function: Cell wall formation [H]
COG id: COG0773
COG function: function code M; UDP-N-acetylmuramate-alanine ligase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family [H]
Homologues:
Organism=Escherichia coli, GI1786279, Length=406, Percent_Identity=32.512315270936, Blast_Score=156, Evalue=2e-39, Organism=Escherichia coli, GI1790680, Length=450, Percent_Identity=24.8888888888889, Blast_Score=105, Evalue=4e-24,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR016040 - InterPro: IPR005758 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.8 [H]
Molecular weight: Translated: 50870; Mature: 50870
Theoretical pI: Translated: 6.76; Mature: 6.76
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 0.9 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 0.9 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLETPKVLLKNLQDCKIHFIGIGGIGISGLAKYLKAQGATISGSDIAISPSVKYLKALGV CCCCHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEECCCCEEECCCHHHHHHCCC EINIPHDPKAIKNQDAIIHSAIIKEDNTEIQRAKELKIPILSRKDALYSILKDKRVFSVC EEECCCCCHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCCEECCHHHHHHHHHCCHHHHHH GAHGKSSITAMLSAIFPFFGAIIGAHSKEFDSNVRESANDSLVFEADESDSSFLFSNPYA CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEECCEE AIVPNTEPEHLEHYDHNLERFFFAYEYFLDHAQKRVIYKEDPFLKNYSKDAIVLEKKDIR EEECCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCCEEEEEHHHHC NIQYILKDGEPHTSFELKDLGAFLVWGLGEHNATNASLAILSALDELDLEEIRNNLLNFK CCHHHEECCCCCCCEEHHHCCEEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCHH GIKKRFDILQKNALILIDDYAHHPTEISATLKSARIYANLLNTQEKIVVIWQAHKYSRLM HHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHH DNLEEFKKCFLEHCDRLIILPVYSASEVKRDIDLKAHFKHYNPTFIDRVRKKGDFLELLV HHHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCEEEECCCCCHHHHHHHCCCCEEEEEE NDNVVETIQKGFVIGFGAGDITYQLRGEM CCCHHHHHHCCCEEEECCCCEEEEEECCC >Mature Secondary Structure MLETPKVLLKNLQDCKIHFIGIGGIGISGLAKYLKAQGATISGSDIAISPSVKYLKALGV CCCCHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEECCCCEEECCCHHHHHHCCC EINIPHDPKAIKNQDAIIHSAIIKEDNTEIQRAKELKIPILSRKDALYSILKDKRVFSVC EEECCCCCHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCCEECCHHHHHHHHHCCHHHHHH GAHGKSSITAMLSAIFPFFGAIIGAHSKEFDSNVRESANDSLVFEADESDSSFLFSNPYA CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEECCEE AIVPNTEPEHLEHYDHNLERFFFAYEYFLDHAQKRVIYKEDPFLKNYSKDAIVLEKKDIR EEECCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCCEEEEEHHHHC NIQYILKDGEPHTSFELKDLGAFLVWGLGEHNATNASLAILSALDELDLEEIRNNLLNFK CCHHHEECCCCCCCEEHHHCCEEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCHH GIKKRFDILQKNALILIDDYAHHPTEISATLKSARIYANLLNTQEKIVVIWQAHKYSRLM HHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHH DNLEEFKKCFLEHCDRLIILPVYSASEVKRDIDLKAHFKHYNPTFIDRVRKKGDFLELLV HHHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCEEEECCCCCHHHHHHHCCCCEEEEEE NDNVVETIQKGFVIGFGAGDITYQLRGEM CCCHHHHHHCCCEEEECCCCEEEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA