Click here to switch to the map view.

The map label for this gene is kdsB [H]

Identifier: 188527036

GI number: 188527036

Start: 225372

End: 226097

Strand: Reverse

Name: kdsB [H]

Synonym: HPSH_01195

Alternate gene names: 188527036

Gene position: 226097-225372 (Counterclockwise)

Preceding gene: 188527042

Following gene: 188527035

Centisome position: 14.06

GC content: 39.94

Gene sequence:

>726_bases
ATGATTATCATTCCTGCTAGATTAAAATCCAGTCGTTTTGAAAATAAAGTGCTAGAAGATATTTTTGGCTTGCCTATGGT
GGTGCGTTGCGCTAAAAATGCGAATCTTGTAGATGAATGCGTGGTCGCTTGCGATGATGAAAGCATCATGCAAACATGCC
AAAAATTCCACATTAAAGCCGTGCTAACCTCCAAACACCATAATAGCGGCACAGAACGCTGTTTGGAAGCGGCGCAAATT
TTAGGGTTAAAAAACGATGAAAGGGTTTTAAATTTGCAAGGCGATGAGCCTTTTTTAGAAAAAGAAGTCATTTTAGCCTT
ATTAGAAGCCACCAAAAACGCCCCTTTCATGGCGACTTGCGCTAAAGTCATTGATGAAGAGCAAGCCAAAAGCCCCAATT
TAGTCAAGGTGGTTTTAGACAGCCAAAGTAACGCTTTGTATTTTTCGCGCTCCCTTATCCCCTTTTTACGAGACGCTGGT
ATGAAACGCCAAACCCCCCTTTTAGGGCATATCGGTATTTATGGCTTCCACAATAAAGAAATATTAGAAGAATTGTGCGC
TTTAAAACCTTGCGTTTTAGAAGAGCTGGAAAAATTAGAGCAATTAAGGGCTTTGTATTATCAAAAAAAGATTGCAGTAA
AAATCGTTCAAAGCCAAAGCGTGGGCATTGACACCAAAGAGGATTTGCAAAACGCTTTGAAAATTTTTAGCCCCAATCTC
CTTTGA

Upstream 100 bases:

>100_bases
AGTTCAATAGCCTAAACCCTTACAATAAAAGGGATAAGCTTTTAATGGGTATAATACCATAAAAATCCCCTATTTTCATA
AGGCTTAAAAAGGTTTAAAG

Downstream 100 bases:

>100_bases
GCGCTAAAATTTACTCAAAGCATTTTTCACCATCAAAAACCTCTTTTTAAATCCAAAAAAAAGCAAAATTTGTTAATTTT
TGCTCAATTTTATTAAAGAT

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MIIIPARLKSSRFENKVLEDIFGLPMVVRCAKNANLVDECVVACDDESIMQTCQKFHIKAVLTSKHHNSGTERCLEAAQI
LGLKNDERVLNLQGDEPFLEKEVILALLEATKNAPFMATCAKVIDEEQAKSPNLVKVVLDSQSNALYFSRSLIPFLRDAG
MKRQTPLLGHIGIYGFHNKEILEELCALKPCVLEELEKLEQLRALYYQKKIAVKIVQSQSVGIDTKEDLQNALKIFSPNL
L

Sequences:

>Translated_241_residues
MIIIPARLKSSRFENKVLEDIFGLPMVVRCAKNANLVDECVVACDDESIMQTCQKFHIKAVLTSKHHNSGTERCLEAAQI
LGLKNDERVLNLQGDEPFLEKEVILALLEATKNAPFMATCAKVIDEEQAKSPNLVKVVLDSQSNALYFSRSLIPFLRDAG
MKRQTPLLGHIGIYGFHNKEILEELCALKPCVLEELEKLEQLRALYYQKKIAVKIVQSQSVGIDTKEDLQNALKIFSPNL
L
>Mature_241_residues
MIIIPARLKSSRFENKVLEDIFGLPMVVRCAKNANLVDECVVACDDESIMQTCQKFHIKAVLTSKHHNSGTERCLEAAQI
LGLKNDERVLNLQGDEPFLEKEVILALLEATKNAPFMATCAKVIDEEQAKSPNLVKVVLDSQSNALYFSRSLIPFLRDAG
MKRQTPLLGHIGIYGFHNKEILEELCALKPCVLEELEKLEQLRALYYQKKIAVKIVQSQSVGIDTKEDLQNALKIFSPNL
L

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=239, Percent_Identity=37.2384937238494, Blast_Score=144, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27065; Mature: 27065

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIIPARLKSSRFENKVLEDIFGLPMVVRCAKNANLVDECVVACDDESIMQTCQKFHIKA
CEEECCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
VLTSKHHNSGTERCLEAAQILGLKNDERVLNLQGDEPFLEKEVILALLEATKNAPFMATC
HHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHH
AKVIDEEQAKSPNLVKVVLDSQSNALYFSRSLIPFLRDAGMKRQTPLLGHIGIYGFHNKE
HHHHHHHHCCCCCEEEEEEECCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCEECCCCHH
ILEELCALKPCVLEELEKLEQLRALYYQKKIAVKIVQSQSVGIDTKEDLQNALKIFSPNL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHCCCC
L
C
>Mature Secondary Structure
MIIIPARLKSSRFENKVLEDIFGLPMVVRCAKNANLVDECVVACDDESIMQTCQKFHIKA
CEEECCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
VLTSKHHNSGTERCLEAAQILGLKNDERVLNLQGDEPFLEKEVILALLEATKNAPFMATC
HHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHH
AKVIDEEQAKSPNLVKVVLDSQSNALYFSRSLIPFLRDAGMKRQTPLLGHIGIYGFHNKE
HHHHHHHHCCCCCEEEEEEECCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCEECCCCHH
ILEELCALKPCVLEELEKLEQLRALYYQKKIAVKIVQSQSVGIDTKEDLQNALKIFSPNL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA