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The map label for this gene is kdgR [H]

Identifier: 187930175

GI number: 187930175

Start: 3247681

End: 3248676

Strand: Reverse

Name: kdgR [H]

Synonym: Rpic_3107

Alternate gene names: 187930175

Gene position: 3248676-3247681 (Counterclockwise)

Preceding gene: 187930180

Following gene: 187930174

Centisome position: 82.4

GC content: 70.48

Gene sequence:

>996_bases
ATGACGGTTCGAATCAAGGACGTAGCGGCGGCGGCGGGGGTGTCGGTGGCAACGGTGTCACGCGCGCTCGCCGGCGGCCC
CGTGAGCGCAGAACTGCGCCGGCGTGTCGATGCGGCGGTGGCGGCGTCCGGGTATCGGCCGAACCTGTCGGCGCGGCGGC
TTCGCTCGCAGCAGGCGCAGACCGTCGGGCTGATCGTCTCGGACATCCGCAACCCGTTCTTCACCAGCGTCAGCCGGGCG
GTGGAAGACGCGGCCTATGCCGCCGGCTTGCGCGTCATCCTGTGCAATTCCGACGAAGACCCCGAGAAGGAGGCGATGTA
CCTGCGCCTGATGGAAGAGGAGCGCGTGACCGGCGTGATCCTCTCGCCAACGCGCGGCATTGCCGAAGCCCAGCAACCTG
TGGACCTCGGCTACCCGGTCGTGCTGATCGATCGTGCCGGCCCCACATGCGGCACCGATGCCGTCGTGCTCGACAACCAG
CAGGCGGCGCAAGCGCTGGCCGAGCACCTCGCCGCGCAGGGTTACCGGCGTATTGGCGGCCTGTTCGGGCGGACGAGCAG
CACGGGCGCTGAGCGTCAGGCCGGATTCGCGACGGCGCTGGCACGCCGCGGCATCACCGCCGAGGCGCGATTCATTCTGC
CCACCGCCGAGGCAGCGGAGGCCGAGACGCTGGCGTGGCTGTCCGGCGCGGAACGTGATCGCCCCGACGCGCTGGTCGCG
AGTAACGCGCAATCGCTGCTCGGCGTGCTGCGTGCGTTGCGGCAGCTTTCGCTGGACGTGCCCCGCGACCTTGCCGTGGC
GGGCTTTGACAACGAGCCCTGGACGGAGCTCGCCGGCCCGGGCATCACCGTGATCGAGCAACCGGTCTACGACATCGGCC
GCATGGCAATGGCGATGCTGCAGGAGCGCCTCGCGCAGCCCACCTTGCCGACGCGCCGTGTGCTGCTCACGGGGCGGCTC
GTCACGCGCGGCTCCACGCCGCTGCGAAGCACTTAG

Upstream 100 bases:

>100_bases
GCTCATCCCAGTATTTACGGGGTTTTCCCTAGGAGAGCTGGAGATTGGAGGCAATGCGGTCATTCGCTATGATGACGCTT
TCTTTGGAAACGATTTCAGC

Downstream 100 bases:

>100_bases
CAGGCGATTACAATTTCCGGATACTCGCGGCGGTGCGACAACGCCGACATGCACCCGCCGCCACCCACTCCGGAGCCCCC
TGATGTCCACCCAAGTCATC

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Kdg operon repressor [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MTVRIKDVAAAAGVSVATVSRALAGGPVSAELRRRVDAAVAASGYRPNLSARRLRSQQAQTVGLIVSDIRNPFFTSVSRA
VEDAAYAAGLRVILCNSDEDPEKEAMYLRLMEEERVTGVILSPTRGIAEAQQPVDLGYPVVLIDRAGPTCGTDAVVLDNQ
QAAQALAEHLAAQGYRRIGGLFGRTSSTGAERQAGFATALARRGITAEARFILPTAEAAEAETLAWLSGAERDRPDALVA
SNAQSLLGVLRALRQLSLDVPRDLAVAGFDNEPWTELAGPGITVIEQPVYDIGRMAMAMLQERLAQPTLPTRRVLLTGRL
VTRGSTPLRST

Sequences:

>Translated_331_residues
MTVRIKDVAAAAGVSVATVSRALAGGPVSAELRRRVDAAVAASGYRPNLSARRLRSQQAQTVGLIVSDIRNPFFTSVSRA
VEDAAYAAGLRVILCNSDEDPEKEAMYLRLMEEERVTGVILSPTRGIAEAQQPVDLGYPVVLIDRAGPTCGTDAVVLDNQ
QAAQALAEHLAAQGYRRIGGLFGRTSSTGAERQAGFATALARRGITAEARFILPTAEAAEAETLAWLSGAERDRPDALVA
SNAQSLLGVLRALRQLSLDVPRDLAVAGFDNEPWTELAGPGITVIEQPVYDIGRMAMAMLQERLAQPTLPTRRVLLTGRL
VTRGSTPLRST
>Mature_330_residues
TVRIKDVAAAAGVSVATVSRALAGGPVSAELRRRVDAAVAASGYRPNLSARRLRSQQAQTVGLIVSDIRNPFFTSVSRAV
EDAAYAAGLRVILCNSDEDPEKEAMYLRLMEEERVTGVILSPTRGIAEAQQPVDLGYPVVLIDRAGPTCGTDAVVLDNQQ
AAQALAEHLAAQGYRRIGGLFGRTSSTGAERQAGFATALARRGITAEARFILPTAEAAEAETLAWLSGAERDRPDALVAS
NAQSLLGVLRALRQLSLDVPRDLAVAGFDNEPWTELAGPGITVIEQPVYDIGRMAMAMLQERLAQPTLPTRRVLLTGRLV
TRGSTPLRST

Specific function: Transcriptional repressor of the kdg operon for pectin utilization [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=336, Percent_Identity=31.547619047619, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1790369, Length=329, Percent_Identity=31.306990881459, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789202, Length=295, Percent_Identity=32.2033898305085, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1788474, Length=341, Percent_Identity=31.3782991202346, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787906, Length=338, Percent_Identity=30.1775147928994, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789068, Length=340, Percent_Identity=29.4117647058824, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1787948, Length=338, Percent_Identity=28.4023668639053, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI48994940, Length=305, Percent_Identity=26.8852459016393, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1787580, Length=314, Percent_Identity=28.343949044586, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789456, Length=339, Percent_Identity=24.188790560472, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1786540, Length=332, Percent_Identity=28.9156626506024, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786268, Length=321, Percent_Identity=26.4797507788162, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790715, Length=335, Percent_Identity=23.2835820895522, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790689, Length=302, Percent_Identity=26.4900662251656, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35238; Mature: 35106

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRIKDVAAAAGVSVATVSRALAGGPVSAELRRRVDAAVAASGYRPNLSARRLRSQQAQ
CEEEEHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TVGLIVSDIRNPFFTSVSRAVEDAAYAAGLRVILCNSDEDPEKEAMYLRLMEEERVTGVI
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEE
LSPTRGIAEAQQPVDLGYPVVLIDRAGPTCGTDAVVLDNQQAAQALAEHLAAQGYRRIGG
ECCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
LFGRTSSTGAERQAGFATALARRGITAEARFILPTAEAAEAETLAWLSGAERDRPDALVA
HHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCHHHH
SNAQSLLGVLRALRQLSLDVPRDLAVAGFDNEPWTELAGPGITVIEQPVYDIGRMAMAML
CCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCCCCEEECCHHHHHHHHHHHHH
QERLAQPTLPTRRVLLTGRLVTRGSTPLRST
HHHHCCCCCCCHHEEEECEEEECCCCCCCCC
>Mature Secondary Structure 
TVRIKDVAAAAGVSVATVSRALAGGPVSAELRRRVDAAVAASGYRPNLSARRLRSQQAQ
EEEEHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TVGLIVSDIRNPFFTSVSRAVEDAAYAAGLRVILCNSDEDPEKEAMYLRLMEEERVTGVI
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEE
LSPTRGIAEAQQPVDLGYPVVLIDRAGPTCGTDAVVLDNQQAAQALAEHLAAQGYRRIGG
ECCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
LFGRTSSTGAERQAGFATALARRGITAEARFILPTAEAAEAETLAWLSGAERDRPDALVA
HHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCHHHH
SNAQSLLGVLRALRQLSLDVPRDLAVAGFDNEPWTELAGPGITVIEQPVYDIGRMAMAML
CCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCCCCEEECCHHHHHHHHHHHHH
QERLAQPTLPTRRVLLTGRLVTRGSTPLRST
HHHHCCCCCCCHHEEEECEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]