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The map label for this gene is argE [H]

Identifier: 187930180

GI number: 187930180

Start: 3255509

End: 3256711

Strand: Reverse

Name: argE [H]

Synonym: Rpic_3112

Alternate gene names: 187930180

Gene position: 3256711-3255509 (Counterclockwise)

Preceding gene: 187930182

Following gene: 187930175

Centisome position: 82.6

GC content: 62.93

Gene sequence:

>1203_bases
ATGTCTGCTGAAGCCATCGCTGTTGCATCGCAACCTTCCGACGAAGTTCTGCAATTGATCCGCACGCTGGTGGCATTCGA
TACCGTTAGCCGCAATTCGAATCTTGGATTGATCGAGTGGGTGCGCGATCGCTTGCGCGGGCAGGGCGCGGACTGTCGTC
TGACCTATGACGCGACGGGCGGTAAGGCAAATCTGTTCGCGACGCTATCGCCAGGCCGCAAGCCGGGGCTGGTGTTGTCT
GGGCATACCGATGTGGTGCCCGTCGATGGGCAGCCGTGGGATACGAACCCGTTTGATGCGCAGATCCGTGACGGCAGCCT
GTACGGGCGCGGCACCGCCGACATGAAGAGCTTCATTGCCGTGGCGCTCGCGAATGTGCCCGGCTTCATGGCGGCGGAGG
GCGGCGCCAGCTTTCATCTTTCGCTGTCGTATGACGAAGAGATCGGCTGCGTCGGCGTGCGCAGTCTGCTGCGTGATCTC
GAGGCGAGCGGCATTCAGCCCGCCGGTTGCATCGTTGGCGAACCCACGTCGATGCGCGCCATCATTGCGCACAAGGGTAA
GCGTGAATACCGATGCTGCGTGCGCGGCAAGGAAGCGCATTCCGCGTTGACGCCGCAGGGCGTGAATGCGATCGAGTTTG
CGGCGCTGCTGATCGCGCATATCCGCTCGCTGGCTGCGCGTCTGGCGGCGGAAGAGGCGCGCGACACCGCCTTTGTCGTG
CCGCATACGACGCTGAATACAGGCACGATCAAAGGTGGTATCGCCACCAACGTGGTGCCGCGCGATTGCGAATTCACCTT
CGATTTCCGCTATCTGCCGGGCATCGATCCGGATTGGCTGTTCGCCGAGGTCGAGCGCTATGCGCAGCAGACGCTGCTGC
CGCAGATGCGTGAAATTTCTGCCGACGCTGACATCAGCTTCGCCATGAAGGCCAACACGCCGGGCCTGTCGATTGCGCCC
TCGCACGAGCTGGTGGCGCTGGCGCAAGCGCTGGCCGATAGCCGGAGTGCGGTTGGCAAGGTCGACTACGGGACCGAAGC
GGGACTGTTCACGCACGCGGGCATTCCGACTGTGGTGTGTGGTCCGGGCAATATCGAGCAGGCGCACAAGCCTAACGAGT
ACATCGAACTTGCGCAGATCGCGCAGTGCGAAGCGTTCATGCGGCGGCTCGCACAACGGCAGCCGCAGTTGCAGCCGGCT
TGA

Upstream 100 bases:

>100_bases
CGAAACGCCTACACTGGACGTCTGTCAATTGACCGCGCGCCGCCCTAGTCAGTTGCCCGTCGCGCTCGCGCGAGCACCAC
GAGACCGACCCGAGCCCATC

Downstream 100 bases:

>100_bases
ATGTAAAAAAACCGGGCACCTGGCCCGGTTTCTTTTTTTAGGGATGCGCGTTCAGCGGATCACTTGCCCGTTAGAGTTGA
TGATCGTCATCTCAACGAAC

Product: acetylornithine deacetylase ArgE

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSAEAIAVASQPSDEVLQLIRTLVAFDTVSRNSNLGLIEWVRDRLRGQGADCRLTYDATGGKANLFATLSPGRKPGLVLS
GHTDVVPVDGQPWDTNPFDAQIRDGSLYGRGTADMKSFIAVALANVPGFMAAEGGASFHLSLSYDEEIGCVGVRSLLRDL
EASGIQPAGCIVGEPTSMRAIIAHKGKREYRCCVRGKEAHSALTPQGVNAIEFAALLIAHIRSLAARLAAEEARDTAFVV
PHTTLNTGTIKGGIATNVVPRDCEFTFDFRYLPGIDPDWLFAEVERYAQQTLLPQMREISADADISFAMKANTPGLSIAP
SHELVALAQALADSRSAVGKVDYGTEAGLFTHAGIPTVVCGPGNIEQAHKPNEYIELAQIAQCEAFMRRLAQRQPQLQPA

Sequences:

>Translated_400_residues
MSAEAIAVASQPSDEVLQLIRTLVAFDTVSRNSNLGLIEWVRDRLRGQGADCRLTYDATGGKANLFATLSPGRKPGLVLS
GHTDVVPVDGQPWDTNPFDAQIRDGSLYGRGTADMKSFIAVALANVPGFMAAEGGASFHLSLSYDEEIGCVGVRSLLRDL
EASGIQPAGCIVGEPTSMRAIIAHKGKREYRCCVRGKEAHSALTPQGVNAIEFAALLIAHIRSLAARLAAEEARDTAFVV
PHTTLNTGTIKGGIATNVVPRDCEFTFDFRYLPGIDPDWLFAEVERYAQQTLLPQMREISADADISFAMKANTPGLSIAP
SHELVALAQALADSRSAVGKVDYGTEAGLFTHAGIPTVVCGPGNIEQAHKPNEYIELAQIAQCEAFMRRLAQRQPQLQPA
>Mature_399_residues
SAEAIAVASQPSDEVLQLIRTLVAFDTVSRNSNLGLIEWVRDRLRGQGADCRLTYDATGGKANLFATLSPGRKPGLVLSG
HTDVVPVDGQPWDTNPFDAQIRDGSLYGRGTADMKSFIAVALANVPGFMAAEGGASFHLSLSYDEEIGCVGVRSLLRDLE
ASGIQPAGCIVGEPTSMRAIIAHKGKREYRCCVRGKEAHSALTPQGVNAIEFAALLIAHIRSLAARLAAEEARDTAFVVP
HTTLNTGTIKGGIATNVVPRDCEFTFDFRYLPGIDPDWLFAEVERYAQQTLLPQMREISADADISFAMKANTPGLSIAPS
HELVALAQALADSRSAVGKVDYGTEAGLFTHAGIPTVVCGPGNIEQAHKPNEYIELAQIAQCEAFMRRLAQRQPQLQPA

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=367, Percent_Identity=34.0599455040872, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1788816, Length=223, Percent_Identity=29.1479820627803, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42869; Mature: 42738

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEAIAVASQPSDEVLQLIRTLVAFDTVSRNSNLGLIEWVRDRLRGQGADCRLTYDATG
CCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEECCC
GKANLFATLSPGRKPGLVLSGHTDVVPVDGQPWDTNPFDAQIRDGSLYGRGTADMKSFIA
CCEEEEEEECCCCCCCEEEECCCCEEECCCCCCCCCCCCCEEECCCEECCCHHHHHHHHH
VALANVPGFMAAEGGASFHLSLSYDEEIGCVGVRSLLRDLEASGIQPAGCIVGEPTSMRA
HHHHCCCCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCCCEE
IIAHKGKREYRCCVRGKEAHSALTPQGVNAIEFAALLIAHIRSLAARLAAEEARDTAFVV
EEECCCCCHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
PHTTLNTGTIKGGIATNVVPRDCEFTFDFRYLPGIDPDWLFAEVERYAQQTLLPQMREIS
ECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHC
ADADISFAMKANTPGLSIAPSHELVALAQALADSRSAVGKVDYGTEAGLFTHAGIPTVVC
CCCCEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEE
GPGNIEQAHKPNEYIELAQIAQCEAFMRRLAQRQPQLQPA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SAEAIAVASQPSDEVLQLIRTLVAFDTVSRNSNLGLIEWVRDRLRGQGADCRLTYDATG
CCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEECCC
GKANLFATLSPGRKPGLVLSGHTDVVPVDGQPWDTNPFDAQIRDGSLYGRGTADMKSFIA
CCEEEEEEECCCCCCCEEEECCCCEEECCCCCCCCCCCCCEEECCCEECCCHHHHHHHHH
VALANVPGFMAAEGGASFHLSLSYDEEIGCVGVRSLLRDLEASGIQPAGCIVGEPTSMRA
HHHHCCCCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCCCEE
IIAHKGKREYRCCVRGKEAHSALTPQGVNAIEFAALLIAHIRSLAARLAAEEARDTAFVV
EEECCCCCHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
PHTTLNTGTIKGGIATNVVPRDCEFTFDFRYLPGIDPDWLFAEVERYAQQTLLPQMREIS
ECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHC
ADADISFAMKANTPGLSIAPSHELVALAQALADSRSAVGKVDYGTEAGLFTHAGIPTVVC
CCCCEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEE
GPGNIEQAHKPNEYIELAQIAQCEAFMRRLAQRQPQLQPA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA