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The map label for this gene is btuC [C]

Identifier: 187929737

GI number: 187929737

Start: 2778995

End: 2780005

Strand: Reverse

Name: btuC [C]

Synonym: Rpic_2666

Alternate gene names: 187929737

Gene position: 2780005-2778995 (Counterclockwise)

Preceding gene: 187929738

Following gene: 187929736

Centisome position: 70.51

GC content: 68.35

Gene sequence:

>1011_bases
ATGACAACACCTGCACTGCCCGCACGCGGTTTTGCCTGGCGACTGTGGTCGCTGCTGGCACTCGCGTGCGTGGTGGTGCT
GGCGGCGTCGTTGATGCTCGGCAGTGTGAAGCTGTCGCTCGCTGAAGTCTGGCGGGCGCTGATCGGCGGTGGCGATAGCC
TGGCTGCGGGCATCGTCATCGAATTGCGCCTGCCGCGCGCGGGCGCTGCATTTGCTGCTGGCGGGCTGTTGGCCTTTGCC
GGGGCGCTCATGCAGATGCTGCTGCGCAATCCGCTGGCCGATCCGTATGTCCTGGGCGTGTCCGGTGGCGGGGCAGTGGC
GGCGCTCACGGCGATGTTGTTTTCGCTGCCGTGGTGGTTGGTGCAGACGAGTGCCGGCGCGGGAGCATTGCTGTCGATGG
CGCTGGTGGCGGCGTTGGCGCGTCAGCACCTGTGGCGCGGTGAGCCCGGCGAGGCCAATGCGCGCCTACTGCTCGGTGGC
GTGGTGATGGCCTCCGGCTGGGTCGGCCTGATCACGCTCATCTTGACGGTGGCGCCCGAGAACAAGCTGCGCGGCATGAT
TTTCTGGATGGTCGGCGACCTCGGTGGCGCCGATCGTTATGCGGGCGCGTTGATGGCGCTCGTGGCGGCGGTGGCCGTGG
TGTTGCCGCATGCGCGCGACCTGAACGTGCTGCTGACCGGCGAAACCCGCGCCCGTGCGCTTGGGGTGCCCGTGGCGCGC
GTGCGTGCGTTGATCTACGTGGTGGCGTCGCTGTGCACGGCGGTAGCGGTGACCATTGCGGGCTCGGTCGCTTTTGTCGG
CCTGCTGGTGCCGCATATGGTGCGCCTGGCGTGGACCCGCGACGTGCGCATCCACTTGCCCGCTACGGCGATGGCCGGCG
GCGGGCTGCTGATGCTGGCCGACCTGATCGCCCGGACGCTGATCGCCCCAACGCAACTGCCGGTGGGTGTGATCACCACC
ATGCTTGGCGTGCCGACGTTTCTCTACCTGCTGATGCGGAGCACGCGATGA

Upstream 100 bases:

>100_bases
AAAACGTGACGAACAAGAACTACCAGTTGATCTATCCGTACAACACGGCGTCGCGTGGGGTGTTCTTCACGCTGTCGTGG
CAACAGCACGAACCGAAGCG

Downstream 100 bases:

>100_bases
GCTGGTTGCGTCGTGCACGTCGGGCCCCTGCACCGGATGCATTCGCGCACTTGGATGCAGCGCCCGAACTCGCGCTGCGC
GACCTGCGCGTGACCATCGA

Product: transport system permease

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTTPALPARGFAWRLWSLLALACVVVLAASLMLGSVKLSLAEVWRALIGGGDSLAAGIVIELRLPRAGAAFAAGGLLAFA
GALMQMLLRNPLADPYVLGVSGGGAVAALTAMLFSLPWWLVQTSAGAGALLSMALVAALARQHLWRGEPGEANARLLLGG
VVMASGWVGLITLILTVAPENKLRGMIFWMVGDLGGADRYAGALMALVAAVAVVLPHARDLNVLLTGETRARALGVPVAR
VRALIYVVASLCTAVAVTIAGSVAFVGLLVPHMVRLAWTRDVRIHLPATAMAGGGLLMLADLIARTLIAPTQLPVGVITT
MLGVPTFLYLLMRSTR

Sequences:

>Translated_336_residues
MTTPALPARGFAWRLWSLLALACVVVLAASLMLGSVKLSLAEVWRALIGGGDSLAAGIVIELRLPRAGAAFAAGGLLAFA
GALMQMLLRNPLADPYVLGVSGGGAVAALTAMLFSLPWWLVQTSAGAGALLSMALVAALARQHLWRGEPGEANARLLLGG
VVMASGWVGLITLILTVAPENKLRGMIFWMVGDLGGADRYAGALMALVAAVAVVLPHARDLNVLLTGETRARALGVPVAR
VRALIYVVASLCTAVAVTIAGSVAFVGLLVPHMVRLAWTRDVRIHLPATAMAGGGLLMLADLIARTLIAPTQLPVGVITT
MLGVPTFLYLLMRSTR
>Mature_335_residues
TTPALPARGFAWRLWSLLALACVVVLAASLMLGSVKLSLAEVWRALIGGGDSLAAGIVIELRLPRAGAAFAAGGLLAFAG
ALMQMLLRNPLADPYVLGVSGGGAVAALTAMLFSLPWWLVQTSAGAGALLSMALVAALARQHLWRGEPGEANARLLLGGV
VMASGWVGLITLILTVAPENKLRGMIFWMVGDLGGADRYAGALMALVAAVAVVLPHARDLNVLLTGETRARALGVPVARV
RALIYVVASLCTAVAVTIAGSVAFVGLLVPHMVRLAWTRDVRIHLPATAMAGGGLLMLADLIARTLIAPTQLPVGVITTM
LGVPTFLYLLMRSTR

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=283, Percent_Identity=37.4558303886926, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1790740, Length=300, Percent_Identity=35.6666666666667, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1790741, Length=331, Percent_Identity=34.7432024169184, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786805, Length=313, Percent_Identity=37.6996805111821, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786347, Length=284, Percent_Identity=32.7464788732394, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786804, Length=324, Percent_Identity=35.4938271604938, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34827; Mature: 34696

Theoretical pI: Translated: 11.59; Mature: 11.59

Prosite motif: PS01098 LIPASE_GDSL_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPALPARGFAWRLWSLLALACVVVLAASLMLGSVKLSLAEVWRALIGGGDSLAAGIVI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEE
ELRLPRAGAAFAAGGLLAFAGALMQMLLRNPLADPYVLGVSGGGAVAALTAMLFSLPWWL
EEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCHHH
VQTSAGAGALLSMALVAALARQHLWRGEPGEANARLLLGGVVMASGWVGLITLILTVAPE
HCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHCCHHHHHHHHHHHCCC
NKLRGMIFWMVGDLGGADRYAGALMALVAAVAVVLPHARDLNVLLTGETRARALGVPVAR
HHHCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCHHH
VRALIYVVASLCTAVAVTIAGSVAFVGLLVPHMVRLAWTRDVRIHLPATAMAGGGLLMLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHCCCCHHHHH
DLIARTLIAPTQLPVGVITTMLGVPTFLYLLMRSTR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTPALPARGFAWRLWSLLALACVVVLAASLMLGSVKLSLAEVWRALIGGGDSLAAGIVI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEE
ELRLPRAGAAFAAGGLLAFAGALMQMLLRNPLADPYVLGVSGGGAVAALTAMLFSLPWWL
EEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCHHH
VQTSAGAGALLSMALVAALARQHLWRGEPGEANARLLLGGVVMASGWVGLITLILTVAPE
HCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHCCHHHHHHHHHHHCCC
NKLRGMIFWMVGDLGGADRYAGALMALVAAVAVVLPHARDLNVLLTGETRARALGVPVAR
HHHCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCHHH
VRALIYVVASLCTAVAVTIAGSVAFVGLLVPHMVRLAWTRDVRIHLPATAMAGGGLLMLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHCCCCHHHHH
DLIARTLIAPTQLPVGVITTMLGVPTFLYLLMRSTR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]