BacMap

Definition	Ralstonia pickettii 12J chromosome chromosome 1, complete sequence.
Accession	NC_010682
Length	3,942,557

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The map label for this gene is fhuC [H]

Identifier: 187929736

GI number: 187929736

Start: 2778153

End: 2778998

Strand: Reverse

Name: fhuC [H]

Synonym: Rpic_2665

Alternate gene names: 187929736

Gene position: 2778998-2778153 (Counterclockwise)

Preceding gene: 187929737

Following gene: 187929735

Centisome position: 70.49

GC content: 67.85

Gene sequence:

>846_bases
ATGAGCTGGTTGCGTCGTGCACGTCGGGCCCCTGCACCGGATGCATTCGCGCACTTGGATGCAGCGCCCGAACTCGCGCT
GCGCGACCTGCGCGTGACCATCGACGGGCGCGTGTTGATTGAGCGGTTGTCGTTGACGGCCAACGCGGGCCAACTCTGGT
GCGTGGTCGGCCCGAACGGCGCGGGCAAGTCGACATGGCTTTCCGTGCTGGCGGGCCTGCGTTCGGAGGACGGCGGCAGC
GTCACGCTCGACGGTGTAGCACTTGCCGATTGGCCGGCACTGGCGATGGCGCGTCGTCGCGCGTTTCTGCCGCAGACCTT
GCATGACTCGTTCCCCATCACCGTGTACCAAGCGGTGATGACCGGCCGCCACCCGCACCTGGCGCGCTGGGAGTGGGAGG
GCGACGCCGATGTCCGCGCCGTTGACGCAGCGGTGTCTGCGCTGCATTTGCAGCCGCTGGTACAACGCGATGTGCGCACG
CTTTCTGGCGGTGAGCGTCAGCGCGTGGCGATGGCTGCCGTGGTGGCGCAGGAGGCGCGCGTGCTGCTGCTTGATGAGCC
CGTCGCGCACCTCGATTTGCATCAGCAGGTTGCCGTGCTGCGCCTGCTGCGCGAAGGTTGCCGCAAACATGGCTGGCTGG
TCGTGCTGACCGTGCATGACTTGAACCTCGCGCGCCGCTACGCCACGCACGCGCTGCTGATGGACGGCGAAGGGCAAACC
ACTGCTGGCATCGCCGCCGATGTGCTGACCCCCGAACACTGCGCACGCGTGCTGCGCACGCCCATTGCCGAGGTGGCCGA
CGGCCGCCGCACGGCCTTGATTCCTGATGACCCCGATGACGACTGA

Upstream 100 bases:

>100_bases
TCGCCCGGACGCTGATCGCCCCAACGCAACTGCCGGTGGGTGTGATCACCACCATGCTTGGCGTGCCGACGTTTCTCTAC
CTGCTGATGCGGAGCACGCG

Downstream 100 bases:

>100_bases
AGACAACAACGATGGCTTGAACGAGCGCCACCGCTCACGCATGCAGCGCAAGAAGGCCGTGGTGGACGCCAAGATTGCCG
CCGCCACGGACGTGCGCGGC

Product: ABC transporter-like protein

Products: NA

Alternate protein names: Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSWLRRARRAPAPDAFAHLDAAPELALRDLRVTIDGRVLIERLSLTANAGQLWCVVGPNGAGKSTWLSVLAGLRSEDGGS
VTLDGVALADWPALAMARRRAFLPQTLHDSFPITVYQAVMTGRHPHLARWEWEGDADVRAVDAAVSALHLQPLVQRDVRT
LSGGERQRVAMAAVVAQEARVLLLDEPVAHLDLHQQVAVLRLLREGCRKHGWLVVLTVHDLNLARRYATHALLMDGEGQT
TAGIAADVLTPEHCARVLRTPIAEVADGRRTALIPDDPDDD

Sequences:

>Translated_281_residues
MSWLRRARRAPAPDAFAHLDAAPELALRDLRVTIDGRVLIERLSLTANAGQLWCVVGPNGAGKSTWLSVLAGLRSEDGGS
VTLDGVALADWPALAMARRRAFLPQTLHDSFPITVYQAVMTGRHPHLARWEWEGDADVRAVDAAVSALHLQPLVQRDVRT
LSGGERQRVAMAAVVAQEARVLLLDEPVAHLDLHQQVAVLRLLREGCRKHGWLVVLTVHDLNLARRYATHALLMDGEGQT
TAGIAADVLTPEHCARVLRTPIAEVADGRRTALIPDDPDDD
>Mature_280_residues
SWLRRARRAPAPDAFAHLDAAPELALRDLRVTIDGRVLIERLSLTANAGQLWCVVGPNGAGKSTWLSVLAGLRSEDGGSV
TLDGVALADWPALAMARRRAFLPQTLHDSFPITVYQAVMTGRHPHLARWEWEGDADVRAVDAAVSALHLQPLVQRDVRTL
SGGERQRVAMAAVVAQEARVLLLDEPVAHLDLHQQVAVLRLLREGCRKHGWLVVLTVHDLNLARRYATHALLMDGEGQTT
AGIAADVLTPEHCARVLRTPIAEVADGRRTALIPDDPDDD

Specific function: Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system [H]

COG id: COG1120

COG function: function code PH; ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI108773784, Length=188, Percent_Identity=27.6595744680851, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI108773782, Length=188, Percent_Identity=27.6595744680851, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI9665248, Length=274, Percent_Identity=25.9124087591241, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI46592956, Length=214, Percent_Identity=28.9719626168224, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI46592898, Length=214, Percent_Identity=28.9719626168224, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI46592971, Length=214, Percent_Identity=28.9719626168224, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI46592915, Length=214, Percent_Identity=28.9719626168224, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI46592964, Length=214, Percent_Identity=28.9719626168224, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI46592978, Length=214, Percent_Identity=28.9719626168224, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI153792144, Length=162, Percent_Identity=30.2469135802469, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1786345, Length=239, Percent_Identity=37.6569037656904, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1786803, Length=242, Percent_Identity=37.603305785124, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1790739, Length=229, Percent_Identity=35.3711790393013, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1788002, Length=221, Percent_Identity=37.10407239819, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87081791, Length=231, Percent_Identity=31.6017316017316, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1787370, Length=201, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789593, Length=234, Percent_Identity=28.6324786324786, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786253, Length=197, Percent_Identity=32.48730964467, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87081834, Length=202, Percent_Identity=30.1980198019802, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789891, Length=239, Percent_Identity=30.5439330543933, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788450, Length=198, Percent_Identity=32.3232323232323, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790544, Length=197, Percent_Identity=30.9644670050761, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788761, Length=242, Percent_Identity=27.6859504132231, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786703, Length=201, Percent_Identity=32.8358208955224, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788225, Length=220, Percent_Identity=27.2727272727273, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788210, Length=206, Percent_Identity=29.6116504854369, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788165, Length=204, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788506, Length=251, Percent_Identity=29.0836653386454, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI48994883, Length=280, Percent_Identity=26.4285714285714, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787105, Length=234, Percent_Identity=31.6239316239316, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790525, Length=219, Percent_Identity=27.3972602739726, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786398, Length=201, Percent_Identity=29.8507462686567, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787712, Length=184, Percent_Identity=27.7173913043478, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789873, Length=220, Percent_Identity=29.0909090909091, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789864, Length=215, Percent_Identity=25.1162790697674, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786319, Length=201, Percent_Identity=27.8606965174129, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787029, Length=200, Percent_Identity=26.5, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787041, Length=211, Percent_Identity=27.0142180094787, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790467, Length=201, Percent_Identity=27.363184079602, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787089, Length=216, Percent_Identity=28.7037037037037, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1786872, Length=191, Percent_Identity=28.2722513089005, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787143, Length=199, Percent_Identity=26.1306532663317, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI145693107, Length=257, Percent_Identity=24.9027237354086, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787500, Length=205, Percent_Identity=27.3170731707317, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789672, Length=202, Percent_Identity=26.2376237623762, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789751, Length=177, Percent_Identity=34.4632768361582, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87081782, Length=239, Percent_Identity=27.1966527196653, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1790162, Length=232, Percent_Identity=26.2931034482759, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1790190, Length=179, Percent_Identity=26.2569832402235, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555800, Length=184, Percent_Identity=28.2608695652174, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320296, Length=211, Percent_Identity=25.5924170616114, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323959, Length=198, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI85724864, Length=230, Percent_Identity=27.3913043478261, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24580555, Length=230, Percent_Identity=27.3913043478261, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI85816269, Length=229, Percent_Identity=27.5109170305677, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24580553, Length=229, Percent_Identity=27.5109170305677, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24582014, Length=200, Percent_Identity=23.5, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582012, Length=200, Percent_Identity=23.5, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45552199, Length=233, Percent_Identity=29.1845493562232, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24581407, Length=233, Percent_Identity=29.1845493562232, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI45552805, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24661270, Length=211, Percent_Identity=27.0142180094787, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355589, Length=211, Percent_Identity=27.0142180094787, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17647219, Length=163, Percent_Identity=29.4478527607362, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24659289, Length=184, Percent_Identity=29.3478260869565, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.34 [H]

Molecular weight: Translated: 30667; Mature: 30536

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWLRRARRAPAPDAFAHLDAAPELALRDLRVTIDGRVLIERLSLTANAGQLWCVVGPNG
CCHHHHHHCCCCCHHHHHCCCCHHHHHHHEEEEECHHHHHHHHHHCCCCCEEEEEECCCC
AGKSTWLSVLAGLRSEDGGSVTLDGVALADWPALAMARRRAFLPQTLHDSFPITVYQAVM
CCHHHHHHHHHHCCCCCCCEEEECCEEECCHHHHHHHHHHHHCCHHHCCCCCHHHHHHHH
TGRHPHLARWEWEGDADVRAVDAAVSALHLQPLVQRDVRTLSGGERQRVAMAAVVAQEAR
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCE
VLLLDEPVAHLDLHQQVAVLRLLREGCRKHGWLVVLTVHDLNLARRYATHALLMDGEGQT
EEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHEEEEECCCCCC
TAGIAADVLTPEHCARVLRTPIAEVADGRRTALIPDDPDDD
CCCHHHHCCCHHHHHHHHHCCHHHHCCCCEEEECCCCCCCC
>Mature Secondary Structure 
SWLRRARRAPAPDAFAHLDAAPELALRDLRVTIDGRVLIERLSLTANAGQLWCVVGPNG
CHHHHHHCCCCCHHHHHCCCCHHHHHHHEEEEECHHHHHHHHHHCCCCCEEEEEECCCC
AGKSTWLSVLAGLRSEDGGSVTLDGVALADWPALAMARRRAFLPQTLHDSFPITVYQAVM
CCHHHHHHHHHHCCCCCCCEEEECCEEECCHHHHHHHHHHHHCCHHHCCCCCHHHHHHHH
TGRHPHLARWEWEGDADVRAVDAAVSALHLQPLVQRDVRTLSGGERQRVAMAAVVAQEAR
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCE
VLLLDEPVAHLDLHQQVAVLRLLREGCRKHGWLVVLTVHDLNLARRYATHALLMDGEGQT
EEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHEEEEECCCCCC
TAGIAADVLTPEHCARVLRTPIAEVADGRRTALIPDDPDDD
CCCHHHHCCCHHHHHHHHHCCHHHHCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3301821; 2823072; 8202364; 9278503 [H]