The gene/protein map for NC_010682 is currently unavailable.
Definition Ralstonia pickettii 12J chromosome chromosome 1, complete sequence.
Accession NC_010682
Length 3,942,557

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The map label for this gene is serS

Identifier: 187929624

GI number: 187929624

Start: 2656705

End: 2658021

Strand: Reverse

Name: serS

Synonym: Rpic_2551

Alternate gene names: 187929624

Gene position: 2658021-2656705 (Counterclockwise)

Preceding gene: 187929625

Following gene: 187929623

Centisome position: 67.42

GC content: 65.22

Gene sequence:

>1317_bases
ATGCTTGATATCCAACTGCTGCGCAAAGACATCGACGCCGTCGCCGCGCGCCTCAAAGATCGCGGCTACGTGCTCGACGT
GGCCGGCTTTGCCGCGCTCGAAGCGGAACGCAAGGCCATCCAGACCCGCACCGAAGAGCTGCAGGCCCGCCGCAACAGCC
TGTCCAAGCAAATCGGTGTGCTCAAGGGCAAGGGCGAGGACGCATCGGGCGTGATGGCCGAGGTGTCGGGCATCGGTGAC
GAGCTGAAAGCGTCTGCCGCGCAACTCGACGTGGTGCAGGCGAAGTTGCAGGACCTGATGCTGTCGATCCCGAACCTGCC
GCACGAAAGCGTGCCGGCCGGCCGCGACGAGACGCAGAACGTGGAAGTGCGCCGCGAAGGCACGCCGCGCACGTTCGACT
TCCCCGTGAAGGACCACGTAGACCTGGGCGCCGCGCTGGGGCTGGATTTTGACGCGGGCGCCAAACTGTCGGGCGCACGA
TTCACCGTCCTGAAAGGGCAGGTGGCGCGTCTGCATCGCGCACTCGCGCAGTTCATGCTCGACACGCACACGCTGGAGCA
CGGCTACACCGAGGCGTACGTGCCGTACATCGTCAACGCTGCTTCGATGCGTGGCACGGGCCAGTTGCCGAAGTTCGAGG
AAGACCTGTTCCGCGTGCCGCGCAAGATGGGGCACAGCGCAGAAGAGGGAGACGGCGAGCGCGTCGAGAACTTCTACCTG
ATCCCGACCGCCGAAGTGCCGCTCACGAACCTCGTGCGCGACGAGATCGTGGCCGCCGATACGCTGCCGATGATGTTCGC
GGCCCATTCACCGTGCTTCCGTTCCGAAGCCGGTTCGTACGGCAAGGACACGCGCGGCATGATCCGCCAGCACCAGTTCG
ACAAGGTTGAGATGGTGCAGATCGTGCAGCCTGAAACCTCGGCCGCCGCGCTGGAGGCCATGACGAACTGCGCCGAGAAC
ATCCTGCGCAAGCTGGAACTGCCGTTCCGCACCGTCGTGCTGTGCACCGGCGACATGGGTTTCGGCAGCACCAAGACGTA
CGACATCGAGGTGTGGATTCCGGCGCAGAACACGTATCGCGAGATCAGCTCGTGCTCCAACATGGGCGACTTCCAGGCGC
GCCGGATGCAGGCGCGCTTCCGCAACGCGCAGGGCAAGCCTGAGCTGGTGCACACGCTCAACGGCTCGGGTCTCGCCGTG
GGCCGTACGCTGGTGGCCCTGCTGGAGAACTACCAGAACGCCGATGGCTCGGTCACGGTGCCGACGGCACTGCGCCCGTA
TCTGGGTGGCCAGGAAGTGCTGAAGCCCGCAGTTTGA

Upstream 100 bases:

>100_bases
AATCCTCCCGCAACAAATAATCCCTACGGGCCGGTACGATAAAATCGGTCTTTTCGGTCATTCAGATCGCTCGCAATCTT
CGCTTTCCTTTTTCTCCACC

Downstream 100 bases:

>100_bases
TCGAGTGGCGCCGGGGCCCTCTTGATCTGGCCGGAAAAATTCTGTTATAGTCGCGGTTTCGCGATTCAGCGACCCAGTTA
CCGGAGAGGTGGCAGAGTGG

Product: seryl-tRNA synthetase

Products: NA

Alternate protein names: Serine--tRNA ligase; SerRS; Seryl-tRNA(Ser/Sec) synthetase

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MLDIQLLRKDIDAVAARLKDRGYVLDVAGFAALEAERKAIQTRTEELQARRNSLSKQIGVLKGKGEDASGVMAEVSGIGD
ELKASAAQLDVVQAKLQDLMLSIPNLPHESVPAGRDETQNVEVRREGTPRTFDFPVKDHVDLGAALGLDFDAGAKLSGAR
FTVLKGQVARLHRALAQFMLDTHTLEHGYTEAYVPYIVNAASMRGTGQLPKFEEDLFRVPRKMGHSAEEGDGERVENFYL
IPTAEVPLTNLVRDEIVAADTLPMMFAAHSPCFRSEAGSYGKDTRGMIRQHQFDKVEMVQIVQPETSAAALEAMTNCAEN
ILRKLELPFRTVVLCTGDMGFGSTKTYDIEVWIPAQNTYREISSCSNMGDFQARRMQARFRNAQGKPELVHTLNGSGLAV
GRTLVALLENYQNADGSVTVPTALRPYLGGQEVLKPAV

Sequences:

>Translated_438_residues
MLDIQLLRKDIDAVAARLKDRGYVLDVAGFAALEAERKAIQTRTEELQARRNSLSKQIGVLKGKGEDASGVMAEVSGIGD
ELKASAAQLDVVQAKLQDLMLSIPNLPHESVPAGRDETQNVEVRREGTPRTFDFPVKDHVDLGAALGLDFDAGAKLSGAR
FTVLKGQVARLHRALAQFMLDTHTLEHGYTEAYVPYIVNAASMRGTGQLPKFEEDLFRVPRKMGHSAEEGDGERVENFYL
IPTAEVPLTNLVRDEIVAADTLPMMFAAHSPCFRSEAGSYGKDTRGMIRQHQFDKVEMVQIVQPETSAAALEAMTNCAEN
ILRKLELPFRTVVLCTGDMGFGSTKTYDIEVWIPAQNTYREISSCSNMGDFQARRMQARFRNAQGKPELVHTLNGSGLAV
GRTLVALLENYQNADGSVTVPTALRPYLGGQEVLKPAV
>Mature_438_residues
MLDIQLLRKDIDAVAARLKDRGYVLDVAGFAALEAERKAIQTRTEELQARRNSLSKQIGVLKGKGEDASGVMAEVSGIGD
ELKASAAQLDVVQAKLQDLMLSIPNLPHESVPAGRDETQNVEVRREGTPRTFDFPVKDHVDLGAALGLDFDAGAKLSGAR
FTVLKGQVARLHRALAQFMLDTHTLEHGYTEAYVPYIVNAASMRGTGQLPKFEEDLFRVPRKMGHSAEEGDGERVENFYL
IPTAEVPLTNLVRDEIVAADTLPMMFAAHSPCFRSEAGSYGKDTRGMIRQHQFDKVEMVQIVQPETSAAALEAMTNCAEN
ILRKLELPFRTVVLCTGDMGFGSTKTYDIEVWIPAQNTYREISSCSNMGDFQARRMQARFRNAQGKPELVHTLNGSGLAV
GRTLVALLENYQNADGSVTVPTALRPYLGGQEVLKPAV

Specific function: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)

COG id: COG0172

COG function: function code J; Seryl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily

Homologues:

Organism=Homo sapiens, GI16306548, Length=485, Percent_Identity=32.9896907216495, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI8923421, Length=366, Percent_Identity=32.5136612021858, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI225579074, Length=415, Percent_Identity=31.566265060241, Blast_Score=179, Evalue=4e-45,
Organism=Escherichia coli, GI1787120, Length=436, Percent_Identity=62.8440366972477, Blast_Score=553, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI17539260, Length=455, Percent_Identity=31.6483516483516, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17542084, Length=333, Percent_Identity=28.8288288288288, Blast_Score=132, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6320226, Length=421, Percent_Identity=32.3040380047506, Blast_Score=209, Evalue=6e-55,
Organism=Saccharomyces cerevisiae, GI6321799, Length=402, Percent_Identity=29.8507462686567, Blast_Score=176, Evalue=8e-45,
Organism=Drosophila melanogaster, GI24581334, Length=475, Percent_Identity=31.3684210526316, Blast_Score=198, Evalue=7e-51,
Organism=Drosophila melanogaster, GI17737985, Length=354, Percent_Identity=33.0508474576271, Blast_Score=165, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYS_RALPJ (B2U9Y5)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001900111.1
- ProteinModelPortal:   B2U9Y5
- SMR:   B2U9Y5
- GeneID:   6289368
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_2551
- HOGENOM:   HBG629391
- OMA:   AHWDLGP
- ProtClustDB:   PRK05431
- GO:   GO:0005737
- HAMAP:   MF_00176
- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR002317
- InterPro:   IPR015866
- InterPro:   IPR010978
- Gene3D:   G3DSA:1.10.287.40
- PANTHER:   PTHR11778
- PIRSF:   PIRSF001529
- PRINTS:   PR00981
- TIGRFAMs:   TIGR00414

Pfam domain/function: PF02403 Seryl_tRNA_N; PF00587 tRNA-synt_2b; SSF46589 tRNA_binding_arm

EC number: =6.1.1.11

Molecular weight: Translated: 48033; Mature: 48033

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: BINDING 297-297 BINDING 396-396

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MLDIQLLRKDIDAVAARLKDRGYVLDVAGFAALEAERKAIQTRTEELQARRNSLSKQIGV
CCCHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LKGKGEDASGVMAEVSGIGDELKASAAQLDVVQAKLQDLMLSIPNLPHESVPAGRDETQN
EECCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
VEVRREGTPRTFDFPVKDHVDLGAALGLDFDAGAKLSGARFTVLKGQVARLHRALAQFML
EEEEECCCCCEECCCCCCCCCCCHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
DTHTLEHGYTEAYVPYIVNAASMRGTGQLPKFEEDLFRVPRKMGHSAEEGDGERVENFYL
HHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
IPTAEVPLTNLVRDEIVAADTLPMMFAAHSPCFRSEAGSYGKDTRGMIRQHQFDKVEMVQ
EECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHCCCCEEEHE
IVQPETSAAALEAMTNCAENILRKLELPFRTVVLCTGDMGFGSTKTYDIEVWIPAQNTYR
EECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEEEECCCHHHH
EISSCSNMGDFQARRMQARFRNAQGKPELVHTLNGSGLAVGRTLVALLENYQNADGSVTV
HHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEC
PTALRPYLGGQEVLKPAV
CHHHCCCCCCHHHHCCCC
>Mature Secondary Structure
MLDIQLLRKDIDAVAARLKDRGYVLDVAGFAALEAERKAIQTRTEELQARRNSLSKQIGV
CCCHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LKGKGEDASGVMAEVSGIGDELKASAAQLDVVQAKLQDLMLSIPNLPHESVPAGRDETQN
EECCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
VEVRREGTPRTFDFPVKDHVDLGAALGLDFDAGAKLSGARFTVLKGQVARLHRALAQFML
EEEEECCCCCEECCCCCCCCCCCHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
DTHTLEHGYTEAYVPYIVNAASMRGTGQLPKFEEDLFRVPRKMGHSAEEGDGERVENFYL
HHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
IPTAEVPLTNLVRDEIVAADTLPMMFAAHSPCFRSEAGSYGKDTRGMIRQHQFDKVEMVQ
EECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHCCCCEEEHE
IVQPETSAAALEAMTNCAENILRKLELPFRTVVLCTGDMGFGSTKTYDIEVWIPAQNTYR
EECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEEEECCCHHHH
EISSCSNMGDFQARRMQARFRNAQGKPELVHTLNGSGLAVGRTLVALLENYQNADGSVTV
HHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEC
PTALRPYLGGQEVLKPAV
CHHHCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA