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The map label for this gene is exbB [H]

Identifier: 187929196

GI number: 187929196

Start: 2232779

End: 2233507

Strand: Direct

Name: exbB [H]

Synonym: Rpic_2117

Alternate gene names: 187929196

Gene position: 2232779-2233507 (Clockwise)

Preceding gene: 187929195

Following gene: 187929197

Centisome position: 56.63

GC content: 64.88

Gene sequence:

>729_bases
ATGCAGGAACTCGGCCTTTCCCACCTCTGGACCCAAGGCGATATCGTCACCCGCGCCACGGCGATTCTGCTGCTCATCAT
GTCGCTCGCCTCGTGGATCGTCATCTTCACCAAGGCGTGGGACATCGTGCGTCTGAAGTCGATGGCACAAGGCGCTGAAA
AGCGTTTCTGGCACTCGGACGATTTCGATCACGCCATACAGACGCTCGGCTCGCCCAAGGACAACCCGTTCCACGCGCTC
GCGCAAACGGGCCGGGAAGCCGCGCAGCACCACCGCGCCAGCCAGCCGCAGTTGCATGATGTGATGGACATCTCCGACTG
GATCACGCGCTCGCTCAAGAGCGCCATCGATGAGGCCGTGGGGCAAATGCAATCGGGCCTAGCCGTGCTGGCATCGGTCG
GCTCGACCGCACCGTTCGTCGGTCTGTTCGGCACGGTGTGGGGCATCTATCACGCCCTGCTCGGGATCGGCGCCGTCGGC
GTGCCCACCATCGACAAAGTCGCCGGCCCCGTGGGTGAGTCGCTCATCATGACGGCCTTCGGTCTGGCCGTGGCCATTCC
GGCGGTGCTGGGCTACAACGCGCTCACGCGCGGCAACAAGGCCATCATCGCCAAGCTCAACCGGTTCGCGCACGACCTGC
ACGCCTATTTCGTGACGGGCGCGCGTCTGCGCCCAGGCGCCTCGCGTGATGACGCCGGCGTGCGCCTAACTGCGGTCAAG
CAGCAGTAA

Upstream 100 bases:

>100_bases
GCCGTGCCCGTGGTGGCCAGCAAGCCGTTCGTCTTCAAGCTCGATAACTAATTCGATTCCGCCTCTCGCTTAGCCTCTCG
CTCAATTCAGGACATTCATC

Downstream 100 bases:

>100_bases
GGAGAGACCATGTCCTTCGGATCTTTCGACAACGATGACGAGGTGATGAGCGAAATCAACATGACGCCGCTGGTCGACGT
CATGCTGGTGCTGCTGATCA

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MQELGLSHLWTQGDIVTRATAILLLIMSLASWIVIFTKAWDIVRLKSMAQGAEKRFWHSDDFDHAIQTLGSPKDNPFHAL
AQTGREAAQHHRASQPQLHDVMDISDWITRSLKSAIDEAVGQMQSGLAVLASVGSTAPFVGLFGTVWGIYHALLGIGAVG
VPTIDKVAGPVGESLIMTAFGLAVAIPAVLGYNALTRGNKAIIAKLNRFAHDLHAYFVTGARLRPGASRDDAGVRLTAVK
QQ

Sequences:

>Translated_242_residues
MQELGLSHLWTQGDIVTRATAILLLIMSLASWIVIFTKAWDIVRLKSMAQGAEKRFWHSDDFDHAIQTLGSPKDNPFHAL
AQTGREAAQHHRASQPQLHDVMDISDWITRSLKSAIDEAVGQMQSGLAVLASVGSTAPFVGLFGTVWGIYHALLGIGAVG
VPTIDKVAGPVGESLIMTAFGLAVAIPAVLGYNALTRGNKAIIAKLNRFAHDLHAYFVTGARLRPGASRDDAGVRLTAVK
QQ
>Mature_242_residues
MQELGLSHLWTQGDIVTRATAILLLIMSLASWIVIFTKAWDIVRLKSMAQGAEKRFWHSDDFDHAIQTLGSPKDNPFHAL
AQTGREAAQHHRASQPQLHDVMDISDWITRSLKSAIDEAVGQMQSGLAVLASVGSTAPFVGLFGTVWGIYHALLGIGAVG
VPTIDKVAGPVGESLIMTAFGLAVAIPAVLGYNALTRGNKAIIAKLNRFAHDLHAYFVTGARLRPGASRDDAGVRLTAVK
QQ

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=218, Percent_Identity=27.5229357798165, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1789381, Length=200, Percent_Identity=29.5, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26023; Mature: 26023

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQELGLSHLWTQGDIVTRATAILLLIMSLASWIVIFTKAWDIVRLKSMAQGAEKRFWHSD
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DFDHAIQTLGSPKDNPFHALAQTGREAAQHHRASQPQLHDVMDISDWITRSLKSAIDEAV
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GQMQSGLAVLASVGSTAPFVGLFGTVWGIYHALLGIGAVGVPTIDKVAGPVGESLIMTAF
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHH
GLAVAIPAVLGYNALTRGNKAIIAKLNRFAHDLHAYFVTGARLRPGASRDDAGVRLTAVK
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEC
QQ
CC
>Mature Secondary Structure
MQELGLSHLWTQGDIVTRATAILLLIMSLASWIVIFTKAWDIVRLKSMAQGAEKRFWHSD
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DFDHAIQTLGSPKDNPFHALAQTGREAAQHHRASQPQLHDVMDISDWITRSLKSAIDEAV
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GQMQSGLAVLASVGSTAPFVGLFGTVWGIYHALLGIGAVGVPTIDKVAGPVGESLIMTAF
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHH
GLAVAIPAVLGYNALTRGNKAIIAKLNRFAHDLHAYFVTGARLRPGASRDDAGVRLTAVK
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEC
QQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]