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The map label for this gene is clpX [H]

Identifier: 187928949

GI number: 187928949

Start: 1968162

End: 1969436

Strand: Reverse

Name: clpX [H]

Synonym: Rpic_1868

Alternate gene names: 187928949

Gene position: 1969436-1968162 (Counterclockwise)

Preceding gene: 187928950

Following gene: 187928948

Centisome position: 49.95

GC content: 57.1

Gene sequence:

>1275_bases
ATGGCGGACAAGAAAGGCTCGACTGGCGAAAAGCTGCTGTACTGCTCGTTTTGCGGCAAGAGCCAGCATGAGGTCAAAAA
ACTGATTGCCGGCCCCTCGGTCTTCATCTGCGATGAATGTATCGACCTGTGCAACGAGATCATCCGGGACGAAGCCGCCA
TCTCCGAAAAGGAAGGTGGTCTGGCGGTCAAGTCCGATCTGCCCACACCGCATGAAATCCGCCAAAGCCTGGACCAATAT
GTGATCGGTCAGGAGCAGGCCAAGAAGATCCTGGCGGTCGCGGTCTACAACCATTACAAGCGTTTGAAGCACCTCGGCAA
GAAGGACGATGTCGAGCTGTCGAAGAGCAATATCCTGCTCATCGGGCCGACTGGCTCGGGCAAGACCCTGCTTGCTCAAA
CGCTGGCGCGTCTGTTGAACGTCCCGTTCGTCATCGCCGACGCCACCACGTTGACCGAAGCCGGCTACGTCGGCGAGGAT
GTCGAAAACATCATTCAGAAGTTGCTGCAGAACTGCAATTACGAGGTGGACAAAGCCCAACGCGGCATCGTCTACATCGA
CGAGATCGACAAGATTTCGCGCAAGTCTGACAACCCTTCCATCACCCGGGACGTTTCTGGCGAAGGCGTGCAACAGGCGC
TGCTGAAGCTGGTGGAAGGGACGATGGCGTCGGTGCCTCCGCAAGGTGGCCGCAAGCATCCAAACCAGGACTTCCTACAA
GTTGATACGACCAACATCTTGTTCATCTGCGGCGGCGCGTTCGATGGTCTGGAAAAGATCATCATGCAGCGCTCCGACAA
GACCGGTATCGGCTTCGGCGCGGAGGTGCAGAGCAAGGAAGAGCGCGACGTCAGCGAAGTTCTGCCGCAAGTGGAGCCGG
AAGATCTCATCAAGTTCGGTCTGATTCCCGAGTTGATCGGCCGTCTGCCCGTGGTGGCGACGCTGGCCAAGCTCGACGAG
GCTGCCTTGATGGAAATCCTGGTCGAACCCAAGAACGCAATCGTCAAGCAGTACCAGAAGCTGCTGGCAATGGAAGGGGT
GGAGCTGGAGATTCGTCCGAGCGGGCTGACGGCAATTGCCCGCAAGGCGATCAAGCGCAAGACGGGGGCGCGCGGTCTGC
GTTCCATCGTTGAGCACGCTTTGATGGATGTGATGTATGACCTCCCCAACCACAAGGGTGTGCAAAAGGTGGTGATCGAT
GAAAGTACGATCTCTGACGAAGGCAAGCCCTTGCTGATTTACGAAGAGCAACCCAAGGTTGCAGGTTCCAACTGA

Upstream 100 bases:

>100_bases
AAAACGAGGCCTCGCGCCTCGTTTTTGCTTCGAACAACACCTGCGGATCGTCGCCAGATAATTTGGCGTATGATGCTGCC
AAGAACTACTGGTAATCGTT

Downstream 100 bases:

>100_bases
CGCGAATGCCCGGCCGGGATGCGCCGTATGCATCCCCTGCAGGAAGCCGTTCGCTCGCGAGCGGCTTTTTTGCTTCGGGA
AACCGGGTCGGCATGCGACT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MADKKGSTGEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAISEKEGGLAVKSDLPTPHEIRQSLDQY
VIGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGED
VENIIQKLLQNCNYEVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFLQ
VDTTNILFICGGAFDGLEKIIMQRSDKTGIGFGAEVQSKEERDVSEVLPQVEPEDLIKFGLIPELIGRLPVVATLAKLDE
AALMEILVEPKNAIVKQYQKLLAMEGVELEIRPSGLTAIARKAIKRKTGARGLRSIVEHALMDVMYDLPNHKGVQKVVID
ESTISDEGKPLLIYEEQPKVAGSN

Sequences:

>Translated_424_residues
MADKKGSTGEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAISEKEGGLAVKSDLPTPHEIRQSLDQY
VIGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGED
VENIIQKLLQNCNYEVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFLQ
VDTTNILFICGGAFDGLEKIIMQRSDKTGIGFGAEVQSKEERDVSEVLPQVEPEDLIKFGLIPELIGRLPVVATLAKLDE
AALMEILVEPKNAIVKQYQKLLAMEGVELEIRPSGLTAIARKAIKRKTGARGLRSIVEHALMDVMYDLPNHKGVQKVVID
ESTISDEGKPLLIYEEQPKVAGSN
>Mature_423_residues
ADKKGSTGEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAISEKEGGLAVKSDLPTPHEIRQSLDQYV
IGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDV
ENIIQKLLQNCNYEVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFLQV
DTTNILFICGGAFDGLEKIIMQRSDKTGIGFGAEVQSKEERDVSEVLPQVEPEDLIKFGLIPELIGRLPVVATLAKLDEA
ALMEILVEPKNAIVKQYQKLLAMEGVELEIRPSGLTAIARKAIKRKTGARGLRSIVEHALMDVMYDLPNHKGVQKVVIDE
STISDEGKPLLIYEEQPKVAGSN

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=306, Percent_Identity=53.2679738562092, Blast_Score=310, Evalue=1e-84,
Organism=Escherichia coli, GI1786642, Length=418, Percent_Identity=72.9665071770335, Blast_Score=608, Evalue=1e-175,
Organism=Escherichia coli, GI1790366, Length=100, Percent_Identity=47, Blast_Score=99, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71988663, Length=401, Percent_Identity=41.645885286783, Blast_Score=281, Evalue=6e-76,
Organism=Caenorhabditis elegans, GI71982908, Length=296, Percent_Identity=46.2837837837838, Blast_Score=263, Evalue=9e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=296, Percent_Identity=46.2837837837838, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI71988660, Length=261, Percent_Identity=43.2950191570881, Blast_Score=191, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6319704, Length=426, Percent_Identity=39.906103286385, Blast_Score=277, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24648291, Length=299, Percent_Identity=47.8260869565217, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI24648289, Length=299, Percent_Identity=47.8260869565217, Blast_Score=280, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46463; Mature: 46332

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKKGSTGEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAISEKEGG
CCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCC
LAVKSDLPTPHEIRQSLDQYVIGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILL
EEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEE
IGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVDKAQ
EECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCEEHHHC
RGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFLQ
CCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
VDTTNILFICGGAFDGLEKIIMQRSDKTGIGFGAEVQSKEERDVSEVLPQVEPEDLIKFG
EECCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCHHHHCCCCCHHHHHHHC
LIPELIGRLPVVATLAKLDEAALMEILVEPKNAIVKQYQKLLAMEGVELEIRPSGLTAIA
CHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHH
RKAIKRKTGARGLRSIVEHALMDVMYDLPNHKGVQKVVIDESTISDEGKPLLIYEEQPKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCC
AGSN
CCCC
>Mature Secondary Structure 
ADKKGSTGEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAISEKEGG
CCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCC
LAVKSDLPTPHEIRQSLDQYVIGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILL
EEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEE
IGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVDKAQ
EECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCEEHHHC
RGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFLQ
CCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
VDTTNILFICGGAFDGLEKIIMQRSDKTGIGFGAEVQSKEERDVSEVLPQVEPEDLIKFG
EECCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCHHHHCCCCCHHHHHHHC
LIPELIGRLPVVATLAKLDEAALMEILVEPKNAIVKQYQKLLAMEGVELEIRPSGLTAIA
CHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHH
RKAIKRKTGARGLRSIVEHALMDVMYDLPNHKGVQKVVIDESTISDEGKPLLIYEEQPKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCC
AGSN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA