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The map label for this gene is ubiB [C]

Identifier: 187928776

GI number: 187928776

Start: 1785322

End: 1787019

Strand: Direct

Name: ubiB [C]

Synonym: Rpic_1693

Alternate gene names: 187928776

Gene position: 1785322-1787019 (Clockwise)

Preceding gene: 187928775

Following gene: 187928778

Centisome position: 45.28

GC content: 60.19

Gene sequence:

>1698_bases
ATGGGCGTCATAACGCATGCGAATCCCGAACCAGCGGTGCGCGAGCGGGTGCCCGCTGAACTGCCACGGCTCTTGTACAT
CCTGCGCGCATTGGCCGGGGCAGGGTGGGCGCATTATGTGGAGCGGCTACGGATTGGCCGTGACGCACTCGAAGCTTCAG
TTGAGGCGGTGCAAGCGACCGATCAGGATGCAAAGCGGCTGAGAGCTACGCTCGAAGGGCTGGGGCCCGCGTTCGTCAAG
TTTGGCCAGCTTCTGAGCCTGCGGCGCGATATGTTGCCGGAGGTCTATATCGAGGAGCTGCAACGGCTCCAGGATGATGT
CGCTGTTTTCCCTGGCGAGCAGGCGCGTGAGATTGTCGAGCGTGAACTGGGCAAATCCGTTCACGCGTTGTTCACCAGTT
TCGATGAGACGCCCCTGGCTGCCGCGTCGATCGGCCAGGTCCATACGGCGCAGTTGATTGACGGCACCAGCGTGGTGGTC
AAGGTGCAGCGCCCCGGCATCGAGCCCATCATTCATGCCGATGTCAGGATCATGCGCTTCTTGGCCCGTCAACTGGAGCG
GTATGTGCCGGAGAGTCGCCGATTTGGCCCGGGCGATCTGGTGGAAGAGTTTGCCCGGCTCATCAACGAAGAATTGGACT
ATCAAGTCGAGGCGCGCAACGGCGATCTCCTGAGGGAGAATTTGCAGGATGATAAGCACGTCTTCGTGCCCCGCATCTTT
TGGGAGCAGACCAGCCGACGTGTCTTGACCATGGAGCGCAGTTTCGGCAAGAAGCTTACGCATATTCCGTCGTCCGAACA
GGAGAGCCGACGGCGCGTGGCGCAGGCGCTGATGGCATCGTTCTTGAAGCAGGTCTTCGAGGACGGCTTCTTTCACGGCG
ACCCGCATCCGGGCAACGTATTTTTGCTGGAGGACGGCCGGCTTTGCTTTCATGACTTTGGCATCATGGGACGGCTGTCC
GCCTATGATCAGGAAGCCTTGGCCCAGTTGATTCTCGCCGTCAGTTCCGGCGAGGTGTCATGGATGGTGGATGCCTATTT
CGAGATGGGGGTGGCGACCGAGGGGGTGGATCGTGAGGCATTTACCCGCGATGCTTCGCAGGCACTTGACGCATACTACG
AAGCCGCCGGGAAAGGCTATTCGTTCGGCGAAATTGTCCGCCAGTTTGCGCTGCTCAGCCAGCGCCATCGGATCAAACTG
CCGCGCCAGTTTCTGCTGGTCTCGAAAGCGTTCATGCTGGTCGAATCGCAAGCGTTGACGCTCGCCCCGGACTTCAACGC
ACTCGCGTCCTTGCGGGAATATGCGCCGCATTTGCTCGGCCGCAAACTATTGCAGGGGGCGAATGTACAGACCGAGTTCA
GCAGGGGATTCCGCACCTTGCGCGCGCTGCATCACGCCGCCGCCTTGCTGCCCGACATTCTGAACCGCACGGTGGAGGCG
CTCAGCAGCGGTAAGGCGACGCTGCATATCAAACACGACCAGTTGCAAGGATTGGAAGCGCATATCGACCGTGCAAGCAA
CCGGCTGAGCTTGAGCTTGATTATTGCGAGCGTCGTGATTGGCTCCTCAATCGTCATGGCGTTCCACAGCGGTCCGCACT
ATGCGGGCATTCCAGTGCTGGGGCTTCTGGGTTTCGTCGTCGCCAGCGTGATGGGCCTCGCTTGGGCGGTTGCGATCCTG
CGATCAGGAAAGTTCTAG

Upstream 100 bases:

>100_bases
CTAAAACGATAGTGCTTGCCGGCTGTCGACGTCCGGAAAGCTGGGCTCGGATGCGTGCATGGCGCGGCAATGGGGAAGGT
GGGCAACGAGGAGAAGGAAC

Downstream 100 bases:

>100_bases
AGGCGCCGCTACAAGCAATGGGGCCTCGAAAGCAACGATGCAGCGCTCCGCTAAAAGACGGCGATGGCACCCGTGGCCAA
CTCCCGTATCAGCGCTGGAA

Product: ABC-1 domain-containing protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MGVITHANPEPAVRERVPAELPRLLYILRALAGAGWAHYVERLRIGRDALEASVEAVQATDQDAKRLRATLEGLGPAFVK
FGQLLSLRRDMLPEVYIEELQRLQDDVAVFPGEQAREIVERELGKSVHALFTSFDETPLAAASIGQVHTAQLIDGTSVVV
KVQRPGIEPIIHADVRIMRFLARQLERYVPESRRFGPGDLVEEFARLINEELDYQVEARNGDLLRENLQDDKHVFVPRIF
WEQTSRRVLTMERSFGKKLTHIPSSEQESRRRVAQALMASFLKQVFEDGFFHGDPHPGNVFLLEDGRLCFHDFGIMGRLS
AYDQEALAQLILAVSSGEVSWMVDAYFEMGVATEGVDREAFTRDASQALDAYYEAAGKGYSFGEIVRQFALLSQRHRIKL
PRQFLLVSKAFMLVESQALTLAPDFNALASLREYAPHLLGRKLLQGANVQTEFSRGFRTLRALHHAAALLPDILNRTVEA
LSSGKATLHIKHDQLQGLEAHIDRASNRLSLSLIIASVVIGSSIVMAFHSGPHYAGIPVLGLLGFVVASVMGLAWAVAIL
RSGKF

Sequences:

>Translated_565_residues
MGVITHANPEPAVRERVPAELPRLLYILRALAGAGWAHYVERLRIGRDALEASVEAVQATDQDAKRLRATLEGLGPAFVK
FGQLLSLRRDMLPEVYIEELQRLQDDVAVFPGEQAREIVERELGKSVHALFTSFDETPLAAASIGQVHTAQLIDGTSVVV
KVQRPGIEPIIHADVRIMRFLARQLERYVPESRRFGPGDLVEEFARLINEELDYQVEARNGDLLRENLQDDKHVFVPRIF
WEQTSRRVLTMERSFGKKLTHIPSSEQESRRRVAQALMASFLKQVFEDGFFHGDPHPGNVFLLEDGRLCFHDFGIMGRLS
AYDQEALAQLILAVSSGEVSWMVDAYFEMGVATEGVDREAFTRDASQALDAYYEAAGKGYSFGEIVRQFALLSQRHRIKL
PRQFLLVSKAFMLVESQALTLAPDFNALASLREYAPHLLGRKLLQGANVQTEFSRGFRTLRALHHAAALLPDILNRTVEA
LSSGKATLHIKHDQLQGLEAHIDRASNRLSLSLIIASVVIGSSIVMAFHSGPHYAGIPVLGLLGFVVASVMGLAWAVAIL
RSGKF
>Mature_564_residues
GVITHANPEPAVRERVPAELPRLLYILRALAGAGWAHYVERLRIGRDALEASVEAVQATDQDAKRLRATLEGLGPAFVKF
GQLLSLRRDMLPEVYIEELQRLQDDVAVFPGEQAREIVERELGKSVHALFTSFDETPLAAASIGQVHTAQLIDGTSVVVK
VQRPGIEPIIHADVRIMRFLARQLERYVPESRRFGPGDLVEEFARLINEELDYQVEARNGDLLRENLQDDKHVFVPRIFW
EQTSRRVLTMERSFGKKLTHIPSSEQESRRRVAQALMASFLKQVFEDGFFHGDPHPGNVFLLEDGRLCFHDFGIMGRLSA
YDQEALAQLILAVSSGEVSWMVDAYFEMGVATEGVDREAFTRDASQALDAYYEAAGKGYSFGEIVRQFALLSQRHRIKLP
RQFLLVSKAFMLVESQALTLAPDFNALASLREYAPHLLGRKLLQGANVQTEFSRGFRTLRALHHAAALLPDILNRTVEAL
SSGKATLHIKHDQLQGLEAHIDRASNRLSLSLIIASVVIGSSIVMAFHSGPHYAGIPVLGLLGFVVASVMGLAWAVAILR
SGKF

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=266, Percent_Identity=34.2105263157895, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI40254938, Length=243, Percent_Identity=33.7448559670782, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI217035081, Length=183, Percent_Identity=35.5191256830601, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI27363457, Length=408, Percent_Identity=28.4313725490196, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI34147522, Length=258, Percent_Identity=30.2325581395349, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI217416386, Length=367, Percent_Identity=28.8828337874659, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI32261307, Length=335, Percent_Identity=25.0746268656716, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI2367309, Length=554, Percent_Identity=27.9783393501805, Blast_Score=216, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI17559152, Length=351, Percent_Identity=28.7749287749288, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32565180, Length=265, Percent_Identity=31.6981132075472, Blast_Score=113, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6321319, Length=262, Percent_Identity=31.6793893129771, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6325148, Length=443, Percent_Identity=22.5733634311512, Blast_Score=106, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6323282, Length=240, Percent_Identity=29.5833333333333, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24662575, Length=282, Percent_Identity=29.0780141843972, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI22024280, Length=231, Percent_Identity=30.3030303030303, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI18859849, Length=256, Percent_Identity=30.078125, Blast_Score=100, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 62939; Mature: 62808

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVITHANPEPAVRERVPAELPRLLYILRALAGAGWAHYVERLRIGRDALEASVEAVQAT
CCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
DQDAKRLRATLEGLGPAFVKFGQLLSLRRDMLPEVYIEELQRLQDDVAVFPGEQAREIVE
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RELGKSVHALFTSFDETPLAAASIGQVHTAQLIDGTSVVVKVQRPGIEPIIHADVRIMRF
HHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHH
LARQLERYVPESRRFGPGDLVEEFARLINEELDYQVEARNGDLLRENLQDDKHVFVPRIF
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHCCCCCEEEHHHHH
WEQTSRRVLTMERSFGKKLTHIPSSEQESRRRVAQALMASFLKQVFEDGFFHGDPHPGNV
HHHHCCHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
FLLEDGRLCFHDFGIMGRLSAYDQEALAQLILAVSSGEVSWMVDAYFEMGVATEGVDREA
EEEECCCCHHHHHCHHHHHHHCCHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCCHHH
FTRDASQALDAYYEAAGKGYSFGEIVRQFALLSQRHRIKLPRQFLLVSKAFMLVESQALT
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEE
LAPDFNALASLREYAPHLLGRKLLQGANVQTEFSRGFRTLRALHHAAALLPDILNRTVEA
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSGKATLHIKHDQLQGLEAHIDRASNRLSLSLIIASVVIGSSIVMAFHSGPHYAGIPVL
HHCCCEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHH
GLLGFVVASVMGLAWAVAILRSGKF
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GVITHANPEPAVRERVPAELPRLLYILRALAGAGWAHYVERLRIGRDALEASVEAVQAT
CCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
DQDAKRLRATLEGLGPAFVKFGQLLSLRRDMLPEVYIEELQRLQDDVAVFPGEQAREIVE
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RELGKSVHALFTSFDETPLAAASIGQVHTAQLIDGTSVVVKVQRPGIEPIIHADVRIMRF
HHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHH
LARQLERYVPESRRFGPGDLVEEFARLINEELDYQVEARNGDLLRENLQDDKHVFVPRIF
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHCCCCCEEEHHHHH
WEQTSRRVLTMERSFGKKLTHIPSSEQESRRRVAQALMASFLKQVFEDGFFHGDPHPGNV
HHHHCCHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
FLLEDGRLCFHDFGIMGRLSAYDQEALAQLILAVSSGEVSWMVDAYFEMGVATEGVDREA
EEEECCCCHHHHHCHHHHHHHCCHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCCHHH
FTRDASQALDAYYEAAGKGYSFGEIVRQFALLSQRHRIKLPRQFLLVSKAFMLVESQALT
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEE
LAPDFNALASLREYAPHLLGRKLLQGANVQTEFSRGFRTLRALHHAAALLPDILNRTVEA
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSGKATLHIKHDQLQGLEAHIDRASNRLSLSLIIASVVIGSSIVMAFHSGPHYAGIPVL
HHCCCEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHH
GLLGFVVASVMGLAWAVAILRSGKF
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA