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The map label for this gene is ldcA [H]

Identifier: 187928420

GI number: 187928420

Start: 1424715

End: 1425641

Strand: Direct

Name: ldcA [H]

Synonym: Rpic_1332

Alternate gene names: 187928420

Gene position: 1424715-1425641 (Clockwise)

Preceding gene: 187928419

Following gene: 187928421

Centisome position: 36.14

GC content: 64.08

Gene sequence:

>927_bases
ATGACCACTGTCCGCCTGATTGCGCCTTCCGGTTATCCGAACGATGCGGCCATCGCCGAGCGCGGCGTGGCGGCACTGGA
AGCGCAGGGCTGCACGGTCGTCAACCGCGAGTGCCTGAGCCGGCAGCATCAGCGTTTTGCCGGCGGTGAACTTGCGCGGC
TGGCAGACCTAAACCAGATCGGTACGGGCGGTGGCCAGGAAATCGCCATGGCCATTCGTGGGGGGTATGGCCTGACGCGC
TTGCTGGACCATATCGACTTCATCGACATCGGCCGCCGCGCGCAGGCGACCGACGCCATCATCGTCGGTCACAGCGATTT
CACCGTGTTTTCGCTGGCGTACCTGGCGGCCACCGGCGGCGTGACGTTTGCCGGCCCGCATGTGTGTTCGGACTTCGGGC
TGGAGACGGTCGACCCGTTCATGGTCGAGCACTTCTGGGGCATCTTGCGAAACCCGACCTATGCGTTGCGCGTGGATGGT
CCGCAACCGACTGGCTGCGCACGGCCGGGCCGCTACGCCGGCACGCTATGGGGCGGCAATCTGGCCATGCTGTGCAGCCT
GATCGGCACGCCGTATCTGCCGGATATCCGCGACGGCATCCTGTTTGTTGAGGACATCAACGAGCATCCGTACCGCGTTG
AACGCATGCTGCTGCAATTGCAGCAGGCTGGCGTGCTCGATGCGCAGCAGGCGCTGTTGTTTGGCGATTTCTCCGGATAT
CGCACCACGCCGTACGACGCCGGCTACGATTTCGACGCCATGCGCGATTATCTGGCCGAACGCCTGTCGATTCCGGTCGT
CACCGGCTTGCCGTTCGGCCATTGCCCGACCAAGGCGACGCTGCCGATTGGCGCACAAGCCGAGCTGGATGTCGACGCCG
CGGGCTTTACGCTGCACTTGTCGGGATACCCGACACTGAAGGCATAA

Upstream 100 bases:

>100_bases
CGCAGGAGTGCGGCGACATGCTGCGCGCCTTCTTCGCCGAGCGCCGCGCAACCCAGAAGGCCGCACGCCTGGCCGCTACT
GAATCCGACGAATCCGCCAC

Downstream 100 bases:

>100_bases
GTCTTCCGGCCATCCGGGTCACGTCCGGGTGGTAAAATCTCGGGTTCTCCAAATGGCGTCCGGTCAAGTGCTTGCCGCGC
CAGATCACCGCTTTTCAAAT

Product: L,D-carboxypeptidase A

Products: NA

Alternate protein names: LD-carboxypeptidase A; Muramoyltetrapeptide carboxypeptidase [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTTVRLIAPSGYPNDAAIAERGVAALEAQGCTVVNRECLSRQHQRFAGGELARLADLNQIGTGGGQEIAMAIRGGYGLTR
LLDHIDFIDIGRRAQATDAIIVGHSDFTVFSLAYLAATGGVTFAGPHVCSDFGLETVDPFMVEHFWGILRNPTYALRVDG
PQPTGCARPGRYAGTLWGGNLAMLCSLIGTPYLPDIRDGILFVEDINEHPYRVERMLLQLQQAGVLDAQQALLFGDFSGY
RTTPYDAGYDFDAMRDYLAERLSIPVVTGLPFGHCPTKATLPIGAQAELDVDAAGFTLHLSGYPTLKA

Sequences:

>Translated_308_residues
MTTVRLIAPSGYPNDAAIAERGVAALEAQGCTVVNRECLSRQHQRFAGGELARLADLNQIGTGGGQEIAMAIRGGYGLTR
LLDHIDFIDIGRRAQATDAIIVGHSDFTVFSLAYLAATGGVTFAGPHVCSDFGLETVDPFMVEHFWGILRNPTYALRVDG
PQPTGCARPGRYAGTLWGGNLAMLCSLIGTPYLPDIRDGILFVEDINEHPYRVERMLLQLQQAGVLDAQQALLFGDFSGY
RTTPYDAGYDFDAMRDYLAERLSIPVVTGLPFGHCPTKATLPIGAQAELDVDAAGFTLHLSGYPTLKA
>Mature_307_residues
TTVRLIAPSGYPNDAAIAERGVAALEAQGCTVVNRECLSRQHQRFAGGELARLADLNQIGTGGGQEIAMAIRGGYGLTRL
LDHIDFIDIGRRAQATDAIIVGHSDFTVFSLAYLAATGGVTFAGPHVCSDFGLETVDPFMVEHFWGILRNPTYALRVDGP
QPTGCARPGRYAGTLWGGNLAMLCSLIGTPYLPDIRDGILFVEDINEHPYRVERMLLQLQQAGVLDAQQALLFGDFSGYR
TTPYDAGYDFDAMRDYLAERLSIPVVTGLPFGHCPTKATLPIGAQAELDVDAAGFTLHLSGYPTLKA

Specific function: Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso- Dap-D-Ala. Can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc- tetrapeptide, G

COG id: COG1619

COG function: function code V; Uncharacterized proteins, homologs of microcin C7 resistance protein MccF

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S66 family [H]

Homologues:

Organism=Escherichia coli, GI1787441, Length=308, Percent_Identity=47.7272727272727, Blast_Score=272, Evalue=2e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003507 [H]

Pfam domain/function: PF02016 Peptidase_S66 [H]

EC number: NA

Molecular weight: Translated: 33165; Mature: 33034

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVRLIAPSGYPNDAAIAERGVAALEAQGCTVVNRECLSRQHQRFAGGELARLADLNQI
CCEEEEEECCCCCCCHHHHHCCHHHHHCCCCEEECHHHHHHHHHHHCCCHHHHHHHHHHH
GTGGGQEIAMAIRGGYGLTRLLDHIDFIDIGRRAQATDAIIVGHSDFTVFSLAYLAATGG
CCCCCCEEEEEEECCCCHHHHHHHCCHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCC
VTFAGPHVCSDFGLETVDPFMVEHFWGILRNPTYALRVDGPQPTGCARPGRYAGTLWGGN
CEECCCHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEECCC
LAMLCSLIGTPYLPDIRDGILFVEDINEHPYRVERMLLQLQQAGVLDAQQALLFGDFSGY
HHHHHHHHCCCCCCCCHHCEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHEEECCCCC
RTTPYDAGYDFDAMRDYLAERLSIPVVTGLPFGHCPTKATLPIGAQAELDVDAAGFTLHL
CCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEECCCEEEEE
SGYPTLKA
CCCCCCCC
>Mature Secondary Structure 
TTVRLIAPSGYPNDAAIAERGVAALEAQGCTVVNRECLSRQHQRFAGGELARLADLNQI
CEEEEEECCCCCCCHHHHHCCHHHHHCCCCEEECHHHHHHHHHHHCCCHHHHHHHHHHH
GTGGGQEIAMAIRGGYGLTRLLDHIDFIDIGRRAQATDAIIVGHSDFTVFSLAYLAATGG
CCCCCCEEEEEEECCCCHHHHHHHCCHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCC
VTFAGPHVCSDFGLETVDPFMVEHFWGILRNPTYALRVDGPQPTGCARPGRYAGTLWGGN
CEECCCHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEECCC
LAMLCSLIGTPYLPDIRDGILFVEDINEHPYRVERMLLQLQQAGVLDAQQALLFGDFSGY
HHHHHHHHCCCCCCCCHHCEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHEEECCCCC
RTTPYDAGYDFDAMRDYLAERLSIPVVTGLPFGHCPTKATLPIGAQAELDVDAAGFTLHL
CCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEECCCEEEEE
SGYPTLKA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]