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The map label for this gene is tadA [H]

Identifier: 187928419

GI number: 187928419

Start: 1424170

End: 1424718

Strand: Direct

Name: tadA [H]

Synonym: Rpic_1331

Alternate gene names: 187928419

Gene position: 1424170-1424718 (Clockwise)

Preceding gene: 187928418

Following gene: 187928420

Centisome position: 36.12

GC content: 69.03

Gene sequence:

>549_bases
ATGACCACACCGCACGTCCTCATCCCGCCTGCCGACATGTCCGCCCATGAGCGCGACGGCTACTGGATGCAGCAGGCGCT
CGTGCAGGCAAAGTTCGCGTGGGGGCAGGGCGAGGTGCCGGTGGGTGCCGTGGTTGTGCGCGGCAACGAGATCGTCGGCG
TCGGCTACAACGCCCCGATTGGCACGCACGACCCATCCGCGCATGCCGAGATGCGCGCGCTGCGCCAGGCCGCCGAGAAG
CTCGGCAACTACCGCCTGCCCGACTGCGAAGTCTTCGTGACCCTGGAGCCTTGCGTGATGTGCGCCGGCGCCATGCTGCA
TGCCCGCGTGGCGCGCGTCGTCTACGGCGCGCCCGATCCCAAGACGGGCGCCGCGGGCAGCATCCTCGACCTGTTTGCAG
AAACGCGGCTGAACCATCAGACCGCCATCACCGGCAGCGTGCTCGCGCAGGAGTGCGGCGACATGCTGCGCGCCTTCTTC
GCCGAGCGCCGCGCAACCCAGAAGGCCGCACGCCTGGCCGCTACTGAATCCGACGAATCCGCCACATGA

Upstream 100 bases:

>100_bases
CGCCTGTCCAAGCTCGTGCTGTACGAAACCCCGAATTGCTGGGCCGACGTGAAGCTCGCGCGTCCGCACGAACAGGATTG
ATGCGACAGCGCCGGATCGC

Downstream 100 bases:

>100_bases
CCACTGTCCGCCTGATTGCGCCTTCCGGTTATCCGAACGATGCGGCCATCGCCGAGCGCGGCGTGGCGGCACTGGAAGCG
CAGGGCTGCACGGTCGTCAA

Product: zinc-binding CMP/dCMP deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MTTPHVLIPPADMSAHERDGYWMQQALVQAKFAWGQGEVPVGAVVVRGNEIVGVGYNAPIGTHDPSAHAEMRALRQAAEK
LGNYRLPDCEVFVTLEPCVMCAGAMLHARVARVVYGAPDPKTGAAGSILDLFAETRLNHQTAITGSVLAQECGDMLRAFF
AERRATQKAARLAATESDESAT

Sequences:

>Translated_182_residues
MTTPHVLIPPADMSAHERDGYWMQQALVQAKFAWGQGEVPVGAVVVRGNEIVGVGYNAPIGTHDPSAHAEMRALRQAAEK
LGNYRLPDCEVFVTLEPCVMCAGAMLHARVARVVYGAPDPKTGAAGSILDLFAETRLNHQTAITGSVLAQECGDMLRAFF
AERRATQKAARLAATESDESAT
>Mature_181_residues
TTPHVLIPPADMSAHERDGYWMQQALVQAKFAWGQGEVPVGAVVVRGNEIVGVGYNAPIGTHDPSAHAEMRALRQAAEKL
GNYRLPDCEVFVTLEPCVMCAGAMLHARVARVVYGAPDPKTGAAGSILDLFAETRLNHQTAITGSVLAQECGDMLRAFFA
ERRATQKAARLAATESDESAT

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=179, Percent_Identity=32.4022346368715, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI145693172, Length=158, Percent_Identity=54.4303797468354, Blast_Score=185, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=38.1443298969072, Blast_Score=80, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17541138, Length=171, Percent_Identity=32.7485380116959, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555996, Length=79, Percent_Identity=41.7721518987342, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=33.1034482758621, Blast_Score=77, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 19488; Mature: 19357

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPHVLIPPADMSAHERDGYWMQQALVQAKFAWGQGEVPVGAVVVRGNEIVGVGYNAPI
CCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEEEECCCCCC
GTHDPSAHAEMRALRQAAEKLGNYRLPDCEVFVTLEPCVMCAGAMLHARVARVVYGAPDP
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCC
KTGAAGSILDLFAETRLNHQTAITGSVLAQECGDMLRAFFAERRATQKAARLAATESDES
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AT
CC
>Mature Secondary Structure 
TTPHVLIPPADMSAHERDGYWMQQALVQAKFAWGQGEVPVGAVVVRGNEIVGVGYNAPI
CCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEEEECCCCCC
GTHDPSAHAEMRALRQAAEKLGNYRLPDCEVFVTLEPCVMCAGAMLHARVARVVYGAPDP
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCC
KTGAAGSILDLFAETRLNHQTAITGSVLAQECGDMLRAFFAERRATQKAARLAATESDES
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AT
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]