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The map label for this gene is yaeL [C]

Identifier: 187928374

GI number: 187928374

Start: 1380159

End: 1381547

Strand: Direct

Name: yaeL [C]

Synonym: Rpic_1285

Alternate gene names: 187928374

Gene position: 1380159-1381547 (Clockwise)

Preceding gene: 187928373

Following gene: 187928375

Centisome position: 35.01

GC content: 63.86

Gene sequence:

>1389_bases
TTGCAGACCGTTTTAGCGTTTGTCTTTGCGATCGCGGTACTGATCGTCATTCACGAACTGGGCCACTACAGTGTCGCGCG
CCTGTGCGGCGTGAAGGTGCTCCGGTTTTCCGTCGGCTTCGGCAAGGTGCTGTTCCGCCATGTGGGGCGCGGCCCTGACC
GCACCGAATGGACGATCTGCGCCATTCCGCTGGGCGGCTACGTCAAGATGTTGGGCGAGGGCTCACGAGACCCCGAGAAA
GATCCGCCCATCCTCCCCGAAGACCTCCCGCGCACCTTCGACCACCAACCGGTTTACAAGCGATTCGCCATCGTGGCTGC
GGGGCCGATCGCCAATTTTCTGCTCGCGATTGTCCTCTATGCAGTGCTGGCATGGGTTGGCGCAATCGAGCCGTTACCTA
TCCTCGGCGCTCCCCCGCCTGGCAGCATTGCTGCCCAGGCCGACCTGCGTGCCAGGGACCGCGTGACCGCGATCGGTACG
GACGATGAAACGCCTGCGCCCGTGCGCAGCTGGAGCGACGTGCGCATGCGCCTGTACTCGGCCGGCATCGCAGGGCGCGA
TGCGCTTGTGCGGGTGCGGGGCGCCGATGGTGTCGAACGCACCGCCCGTCTTCATGGCTTGCCGAGCGCAGCCCGTACGC
CGCAGGCCGACGTGATCGACCAGATTGGTCTGCGCCTGCTCGGTGGCCCGGTCACCGTCGTCGATGTGCTGCCCTCCAGT
GCCGCGGCACGTGCCGGGTTGCGGGCGGGTGACCAGATCGTTCGCTTCGCCGGCCAGCCTGCCGATCAGGCGATGGACCT
CATCCGGCAGATCCGCGCCATGCCCGAACAGAACGCGTCGATCGATATCCTGCGCAACGATCAGCCCATGACGTTGCCCG
TTCGCCCGGATGCAGACGCCGATCCCAAGAACCCCACGGGCCCGAAGATCGGTAAGCTCGGCGCGCAGCTCAACCAGAAG
GTGGAAACGGCGATGATCCGGGATGAGCCGGTCGCCGCATTGGGCCACGCCGTGGGCGAGGTCTGGCGGACTTCGGCGCT
ATCGCTGCAGGTGCTGGCCAAGATGATCGTTGGTCAGGCGTCTCTGCAGAACCTGAGCGGGCCGATCACGGTGGCGGACT
TCGCAGGCAAGGCGGCAAGCCTTGGCTGGCAGACGTTTGTGAGCTTTCTCGCGTTGATCAGCGTGAGTCTCGGCGTCCTG
AACTTCTTGCCAGTTCCGGTATTGGATGGGGGGCATTTGCTGTATTATTGCGTGGAATTTTTGACTGGCCGACCCGTGCC
GGAATCCTGGCAAGCAGTCCTTCAGAAGATCGGCGTCGCCTGCATCCTGCTTCTCACTTCGCTCGCCCTGTACAACGATT
TGAGTCGGTTATTTCTGACTCGCGGCTAA

Upstream 100 bases:

>100_bases
TGCCGGCCGCCTGAAAGCGCCCCGTCAGAGCAAGCGGGTAACATAGCGGCTTCGCGCGGGGTCAACCAGCGCGTGCCCTT
CAGTGCATCCGGAGAAGGTT

Downstream 100 bases:

>100_bases
ACCGTATTCAACTTGGGTCGGTAAGCCACATCGTTGCCACCGGCGTGAGCGGGCAACTCAGGGTTTTGAAAACACTCAGA
AGTGGATTCCGATTGAATCC

Product: membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MQTVLAFVFAIAVLIVIHELGHYSVARLCGVKVLRFSVGFGKVLFRHVGRGPDRTEWTICAIPLGGYVKMLGEGSRDPEK
DPPILPEDLPRTFDHQPVYKRFAIVAAGPIANFLLAIVLYAVLAWVGAIEPLPILGAPPPGSIAAQADLRARDRVTAIGT
DDETPAPVRSWSDVRMRLYSAGIAGRDALVRVRGADGVERTARLHGLPSAARTPQADVIDQIGLRLLGGPVTVVDVLPSS
AAARAGLRAGDQIVRFAGQPADQAMDLIRQIRAMPEQNASIDILRNDQPMTLPVRPDADADPKNPTGPKIGKLGAQLNQK
VETAMIRDEPVAALGHAVGEVWRTSALSLQVLAKMIVGQASLQNLSGPITVADFAGKAASLGWQTFVSFLALISVSLGVL
NFLPVPVLDGGHLLYYCVEFLTGRPVPESWQAVLQKIGVACILLLTSLALYNDLSRLFLTRG

Sequences:

>Translated_462_residues
MQTVLAFVFAIAVLIVIHELGHYSVARLCGVKVLRFSVGFGKVLFRHVGRGPDRTEWTICAIPLGGYVKMLGEGSRDPEK
DPPILPEDLPRTFDHQPVYKRFAIVAAGPIANFLLAIVLYAVLAWVGAIEPLPILGAPPPGSIAAQADLRARDRVTAIGT
DDETPAPVRSWSDVRMRLYSAGIAGRDALVRVRGADGVERTARLHGLPSAARTPQADVIDQIGLRLLGGPVTVVDVLPSS
AAARAGLRAGDQIVRFAGQPADQAMDLIRQIRAMPEQNASIDILRNDQPMTLPVRPDADADPKNPTGPKIGKLGAQLNQK
VETAMIRDEPVAALGHAVGEVWRTSALSLQVLAKMIVGQASLQNLSGPITVADFAGKAASLGWQTFVSFLALISVSLGVL
NFLPVPVLDGGHLLYYCVEFLTGRPVPESWQAVLQKIGVACILLLTSLALYNDLSRLFLTRG
>Mature_462_residues
MQTVLAFVFAIAVLIVIHELGHYSVARLCGVKVLRFSVGFGKVLFRHVGRGPDRTEWTICAIPLGGYVKMLGEGSRDPEK
DPPILPEDLPRTFDHQPVYKRFAIVAAGPIANFLLAIVLYAVLAWVGAIEPLPILGAPPPGSIAAQADLRARDRVTAIGT
DDETPAPVRSWSDVRMRLYSAGIAGRDALVRVRGADGVERTARLHGLPSAARTPQADVIDQIGLRLLGGPVTVVDVLPSS
AAARAGLRAGDQIVRFAGQPADQAMDLIRQIRAMPEQNASIDILRNDQPMTLPVRPDADADPKNPTGPKIGKLGAQLNQK
VETAMIRDEPVAALGHAVGEVWRTSALSLQVLAKMIVGQASLQNLSGPITVADFAGKAASLGWQTFVSFLALISVSLGVL
NFLPVPVLDGGHLLYYCVEFLTGRPVPESWQAVLQKIGVACILLLTSLALYNDLSRLFLTRG

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=461, Percent_Identity=38.6117136659436, Blast_Score=262, Evalue=4e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49450; Mature: 49450

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTVLAFVFAIAVLIVIHELGHYSVARLCGVKVLRFSVGFGKVLFRHVGRGPDRTEWTIC
CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEE
AIPLGGYVKMLGEGSRDPEKDPPILPEDLPRTFDHQPVYKRFAIVAAGPIANFLLAIVLY
EECCCHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
AVLAWVGAIEPLPILGAPPPGSIAAQADLRARDRVTAIGTDDETPAPVRSWSDVRMRLYS
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCEEEECCCCCCCCCCCCHHHHHHHHHH
AGIAGRDALVRVRGADGVERTARLHGLPSAARTPQADVIDQIGLRLLGGPVTVVDVLPSS
CCCCCCCCEEEEECCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCH
AAARAGLRAGDQIVRFAGQPADQAMDLIRQIRAMPEQNASIDILRNDQPMTLPVRPDADA
HHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCC
DPKNPTGPKIGKLGAQLNQKVETAMIRDEPVAALGHAVGEVWRTSALSLQVLAKMIVGQA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLQNLSGPITVADFAGKAASLGWQTFVSFLALISVSLGVLNFLPVPVLDGGHLLYYCVEF
HHHHCCCCEEEHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LTGRPVPESWQAVLQKIGVACILLLTSLALYNDLSRLFLTRG
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQTVLAFVFAIAVLIVIHELGHYSVARLCGVKVLRFSVGFGKVLFRHVGRGPDRTEWTIC
CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEE
AIPLGGYVKMLGEGSRDPEKDPPILPEDLPRTFDHQPVYKRFAIVAAGPIANFLLAIVLY
EECCCHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
AVLAWVGAIEPLPILGAPPPGSIAAQADLRARDRVTAIGTDDETPAPVRSWSDVRMRLYS
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCEEEECCCCCCCCCCCCHHHHHHHHHH
AGIAGRDALVRVRGADGVERTARLHGLPSAARTPQADVIDQIGLRLLGGPVTVVDVLPSS
CCCCCCCCEEEEECCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCH
AAARAGLRAGDQIVRFAGQPADQAMDLIRQIRAMPEQNASIDILRNDQPMTLPVRPDADA
HHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCC
DPKNPTGPKIGKLGAQLNQKVETAMIRDEPVAALGHAVGEVWRTSALSLQVLAKMIVGQA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLQNLSGPITVADFAGKAASLGWQTFVSFLALISVSLGVLNFLPVPVLDGGHLLYYCVEF
HHHHCCCCEEEHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LTGRPVPESWQAVLQKIGVACILLLTSLALYNDLSRLFLTRG
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]