Click here to switch to the map view.

The map label for this gene is 187928324

Identifier: 187928324

GI number: 187928324

Start: 1322915

End: 1323613

Strand: Direct

Name: 187928324

Synonym: Rpic_1235

Alternate gene names: NA

Gene position: 1322915-1323613 (Clockwise)

Preceding gene: 187928321

Following gene: 187928325

Centisome position: 33.55

GC content: 64.52

Gene sequence:

>699_bases
ATGCGTTCGATTCGGGCGGTGGTGTTCGATGCCTATGGCACGTTGTTCGACGTGTATTCCGTGGCCGCGCGCGCCGAGCA
ACTGTTTGCCGGCAAGGGCGAAGCACTGTCGGTGCTGTGGCGCGACAAGCAGATCGACTACACGCGCATCCGCTCGCTGG
CCGGCCCCTCGGGTGAACACTACAAGCCGTTCTGGGACATCACCGTCGATGCGCTGCGCTATGCGGCGGCACGCCTGGGC
GTAGAGCTTTCCGCCCACGACGAAGCCACGCTGATGCGCGAATATGCCTGCCTGTCGGCGTTTCCCGAGAACGTGCCCGC
GCTGCGCCGCCTGCGTGAGATGGGCTTGCCGCTGGGCATCCTCTCCAACGGCAACCCGCAGATGCTCGACATTGCCGTGA
AGAGTGCCGGCATGTCCGGGCTGTTCGATCACGTGCTGTCGGTCGACGCGGTCAAGCTCTACAAGACCGCGCCGCAGGCC
TATGCGCTGGCGCCACAAGCGTTTGGTGTGCCGGCGGAACAGATTCTGTTTGTCTCGTCCAATGGCTGGGATGCCTGCGG
CGCGACGTGGTACGGCTTCACAACGTTCTGGATCAACCGCCTGGGGCATCCGCCCGAGGCACTCGACGTGGCGCCTACCG
CGGCCGGCCACGATATGCGCGATCTGCTGCAGTTCGTGCAGGCAACACAAGCGACGTAA

Upstream 100 bases:

>100_bases
GCGTCAGCTTTTCTACAATGGCCCTCGTTGCGAAGGTCGGCAAGGCGTTCTGCGTAATGGAACGTACAAGCGGGTAGCCT
TCGGGTCCGTGGAGCTTCTG

Downstream 100 bases:

>100_bases
GGCATTGCATTGAATCGGCCCAGTCATAGGGCCAAAGTAAGACCAAAGCGCGTTCAACCCTCACATCATCCTCTGGAGAA
CAACCATGGCGCTCACGCTG

Product: haloacid dehalogenase I

Products: NA

Alternate protein names: 2-haloalkanoic acid dehalogenase; Halocarboxylic acid halidohydrolase; L-2-haloacid dehalogenase; L-DEX [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MRSIRAVVFDAYGTLFDVYSVAARAEQLFAGKGEALSVLWRDKQIDYTRIRSLAGPSGEHYKPFWDITVDALRYAAARLG
VELSAHDEATLMREYACLSAFPENVPALRRLREMGLPLGILSNGNPQMLDIAVKSAGMSGLFDHVLSVDAVKLYKTAPQA
YALAPQAFGVPAEQILFVSSNGWDACGATWYGFTTFWINRLGHPPEALDVAPTAAGHDMRDLLQFVQATQAT

Sequences:

>Translated_232_residues
MRSIRAVVFDAYGTLFDVYSVAARAEQLFAGKGEALSVLWRDKQIDYTRIRSLAGPSGEHYKPFWDITVDALRYAAARLG
VELSAHDEATLMREYACLSAFPENVPALRRLREMGLPLGILSNGNPQMLDIAVKSAGMSGLFDHVLSVDAVKLYKTAPQA
YALAPQAFGVPAEQILFVSSNGWDACGATWYGFTTFWINRLGHPPEALDVAPTAAGHDMRDLLQFVQATQAT
>Mature_232_residues
MRSIRAVVFDAYGTLFDVYSVAARAEQLFAGKGEALSVLWRDKQIDYTRIRSLAGPSGEHYKPFWDITVDALRYAAARLG
VELSAHDEATLMREYACLSAFPENVPALRRLREMGLPLGILSNGNPQMLDIAVKSAGMSGLFDHVLSVDAVKLYKTAPQA
YALAPQAFGVPAEQILFVSSNGWDACGATWYGFTTFWINRLGHPPEALDVAPTAAGHDMRDLLQFVQATQAT

Specific function: Catalyzes the hydrolytic dehalogenation of small (S)-2- haloalkanoic acids to yield the corresponding (R)-2- hydroxyalkanoic acids. Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-2 [H]

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. S-2- haloalkanoic acid dehalogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006388
- InterPro:   IPR006328
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.8.1.2 [H]

Molecular weight: Translated: 25414; Mature: 25414

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSIRAVVFDAYGTLFDVYSVAARAEQLFAGKGEALSVLWRDKQIDYTRIRSLAGPSGEH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHCCCCCCC
YKPFWDITVDALRYAAARLGVELSAHDEATLMREYACLSAFPENVPALRRLREMGLPLGI
CCCHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEE
LSNGNPQMLDIAVKSAGMSGLFDHVLSVDAVKLYKTAPQAYALAPQAFGVPAEQILFVSS
ECCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHHHHCCHHHEECCHHHCCCHHHEEEEEC
NGWDACGATWYGFTTFWINRLGHPPEALDVAPTAAGHDMRDLLQFVQATQAT
CCCCCCCCHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRSIRAVVFDAYGTLFDVYSVAARAEQLFAGKGEALSVLWRDKQIDYTRIRSLAGPSGEH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHCCCCCCC
YKPFWDITVDALRYAAARLGVELSAHDEATLMREYACLSAFPENVPALRRLREMGLPLGI
CCCHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEE
LSNGNPQMLDIAVKSAGMSGLFDHVLSVDAVKLYKTAPQAYALAPQAFGVPAEQILFVSS
ECCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHHHHCCHHHEECCHHHCCCHHHEEEEEC
NGWDACGATWYGFTTFWINRLGHPPEALDVAPTAAGHDMRDLLQFVQATQAT
CCCCCCCCHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7944368; 7490277; 8702766; 9614112 [H]