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The map label for this gene is ydgM [C]

Identifier: 187934487

GI number: 187934487

Start: 2078815

End: 2080755

Strand: Reverse

Name: ydgM [C]

Synonym: CLL_A2000

Alternate gene names: 187934487

Gene position: 2080755-2078815 (Counterclockwise)

Preceding gene: 187933101

Following gene: 187933250

Centisome position: 54.75

GC content: 31.43

Gene sequence:

>1941_bases
ATGTCATGCAAAAATACTACATATATACAAAGTTTATTGGGTTCAGTATTTTCAACTTTTAGCGAAGATGAATTAAAAGA
AATAACAGGAAATGAAAAAAGAAGTATAGCCATTTGTGGAAAAATAAATAATCCGGGAATAATAGAAGTTCCAGTTGGGG
CAACACTTAGAGATATATTAGAACTTTGCGGAGGTGTTGTAAATAACAGTAGTTTTAAAGCTGCTCAAATAGGAATTCCT
TTTGGCGGATTTCTAAATGAAGGTAGTTTAGATAAAGAATTTAATTTTGGACTATTTTATGAAAATATTAGTAGAGCTAT
TATTATATTGTCAGAAGAAGATTGTATAATACAATACGGAAAATTCTACATAGAGTATTTATTAACCAAAATTAAAGATG
GTACTTATAAAAATTATGAAATAGTTAAAAAAGAAATAACTAAAATGCTTAAGGTTTTAGATAGAATAAGTAAAGGTGTA
TCTGATATGCGAGACATCTATATTTTAAGAAGTCTTGCAGCTGATGTGAAAGATAAGATGCATCAAAAGCATAATTTAAT
GGAAGAAATAGTTGAAAACTTTTATGAAGAAATAGAAGAACATATAGAAGAAAAGAAGTGTTATACAGCCCAATGCAATC
ATCTTATAAAACTAACAATTACTAAGAAATGTATTGGATGTGGAAGTTGTAAAAGAGCATGTCCTGTTGATTGCATTGAT
GGGGAACTAAAAAAGCAACATAATATAGATTATAATAAATGTACACATTGTGGAGCTTGTATATCAGCTTGTCCTGTAGA
TGCAATAACAGCAGGAAATAATACAATTAAGTTTCTTAGAGATTTAGCTACACCTAATAAAGTGGTAATTACTCAAATGG
CACCAGCTATAAGAGTTGCTATAGGGGAAGCTTTTGGATTTGAACCAGGAGAAAATGTAGAAAAGAAGATAGCAGCAGGA
CTTAGAAAGCTAGGAGTAGATTATGTTTTTGATACTACTTGGGGAGCAGATTTAACTATAATGGAAGAAGCGGCAGAACT
TCAAGAAAGATTGGAAAAATACTTAGCAGGAGATGAAAATGTTAAGCTTCCAATTCTTACTTCATGTTGTCCTTCATGGA
TCAAGTTTATAGAAAATAATTATGCAGATATGTTAGAAGTTCCTTCTTCAGCAAAATCACCAATGCAAATGTTTGCCACA
ATAGCAAAAGAAATATGGGCAAAGGAAAAAGGTCTTCAAAGAGAAGAAGTAACTTCAGTTGCAATTATGCCATGTGTTGC
TAAAATATATGAAGCATCAAGAGTAGAATTTTCAGTAGATATGAATTATGATGTTGACTATGTAATTACTACAAGGGAAC
TTATAAAAATATTTGAAAAATCAGGAATAGATTTAAAAGAGATTGAGGATGAAGAGATAGATTCTGTTATGGGAGAATAT
ACTGGTGCCGGAATTATCTTCGGTAGAACTGGTGGAGTTATAGAGGCTGCTACTAGAACAGCAATTGAAAATATGACAGG
AAAAAGAATTGATAATATAGAATTTGAAGGCCTTAGAGGATGGGATGGATTTAGAATTTGTGAACTTGAAGTTGGTGAGC
TTAAGCTTAGAATAGGAGTTGCACATGGACTTAAAGAAGCTGCAAAGATGTTAGATAAAATAAGATCAGGTGAAGAATTC
TTTCATGCAATTGAAATTATGGCTTGCGTAGGTGGATGCGTAGGTGGCGGTGGTCAACCTAAAATAAGGAAAAATAAACA
ACAAGTTTTAGAAAAAAGAGCAGAAGGATTAAATGATATAGATAGAGCTAAAGTACTTAGAAGGTCAAATGAAAATCCAG
AAGTACTTGCTCTTTATAAAAAATATTTAGATCATCCATTAAGTCACAAGGCTCATGAATTACTTCATACGAAGTATTTT
CCAAAAGTTAAGAAGAGATAA

Upstream 100 bases:

>100_bases
TGTATAATGTAACTAAAGAATAATTGTTTTTACATAAAATATATTTTAATGAAATATTTAGAATTACTTAATATGATTTT
AGACTTAAGGAGTGGATATT

Downstream 100 bases:

>100_bases
GTTTTATGCTATATAAAAAAGGTAGACTAAAATTTATTAGTCTACCTTTTTATATTGTAAATTTTAATTATAAGATTAAA
ATTCTACTAGAATCTAAAGT

Product: periplasmic [Fe] hydrogenase 1

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 646; Mature: 645

Protein sequence:

>646_residues
MSCKNTTYIQSLLGSVFSTFSEDELKEITGNEKRSIAICGKINNPGIIEVPVGATLRDILELCGGVVNNSSFKAAQIGIP
FGGFLNEGSLDKEFNFGLFYENISRAIIILSEEDCIIQYGKFYIEYLLTKIKDGTYKNYEIVKKEITKMLKVLDRISKGV
SDMRDIYILRSLAADVKDKMHQKHNLMEEIVENFYEEIEEHIEEKKCYTAQCNHLIKLTITKKCIGCGSCKRACPVDCID
GELKKQHNIDYNKCTHCGACISACPVDAITAGNNTIKFLRDLATPNKVVITQMAPAIRVAIGEAFGFEPGENVEKKIAAG
LRKLGVDYVFDTTWGADLTIMEEAAELQERLEKYLAGDENVKLPILTSCCPSWIKFIENNYADMLEVPSSAKSPMQMFAT
IAKEIWAKEKGLQREEVTSVAIMPCVAKIYEASRVEFSVDMNYDVDYVITTRELIKIFEKSGIDLKEIEDEEIDSVMGEY
TGAGIIFGRTGGVIEAATRTAIENMTGKRIDNIEFEGLRGWDGFRICELEVGELKLRIGVAHGLKEAAKMLDKIRSGEEF
FHAIEIMACVGGCVGGGGQPKIRKNKQQVLEKRAEGLNDIDRAKVLRRSNENPEVLALYKKYLDHPLSHKAHELLHTKYF
PKVKKR

Sequences:

>Translated_646_residues
MSCKNTTYIQSLLGSVFSTFSEDELKEITGNEKRSIAICGKINNPGIIEVPVGATLRDILELCGGVVNNSSFKAAQIGIP
FGGFLNEGSLDKEFNFGLFYENISRAIIILSEEDCIIQYGKFYIEYLLTKIKDGTYKNYEIVKKEITKMLKVLDRISKGV
SDMRDIYILRSLAADVKDKMHQKHNLMEEIVENFYEEIEEHIEEKKCYTAQCNHLIKLTITKKCIGCGSCKRACPVDCID
GELKKQHNIDYNKCTHCGACISACPVDAITAGNNTIKFLRDLATPNKVVITQMAPAIRVAIGEAFGFEPGENVEKKIAAG
LRKLGVDYVFDTTWGADLTIMEEAAELQERLEKYLAGDENVKLPILTSCCPSWIKFIENNYADMLEVPSSAKSPMQMFAT
IAKEIWAKEKGLQREEVTSVAIMPCVAKIYEASRVEFSVDMNYDVDYVITTRELIKIFEKSGIDLKEIEDEEIDSVMGEY
TGAGIIFGRTGGVIEAATRTAIENMTGKRIDNIEFEGLRGWDGFRICELEVGELKLRIGVAHGLKEAAKMLDKIRSGEEF
FHAIEIMACVGGCVGGGGQPKIRKNKQQVLEKRAEGLNDIDRAKVLRRSNENPEVLALYKKYLDHPLSHKAHELLHTKYF
PKVKKR
>Mature_645_residues
SCKNTTYIQSLLGSVFSTFSEDELKEITGNEKRSIAICGKINNPGIIEVPVGATLRDILELCGGVVNNSSFKAAQIGIPF
GGFLNEGSLDKEFNFGLFYENISRAIIILSEEDCIIQYGKFYIEYLLTKIKDGTYKNYEIVKKEITKMLKVLDRISKGVS
DMRDIYILRSLAADVKDKMHQKHNLMEEIVENFYEEIEEHIEEKKCYTAQCNHLIKLTITKKCIGCGSCKRACPVDCIDG
ELKKQHNIDYNKCTHCGACISACPVDAITAGNNTIKFLRDLATPNKVVITQMAPAIRVAIGEAFGFEPGENVEKKIAAGL
RKLGVDYVFDTTWGADLTIMEEAAELQERLEKYLAGDENVKLPILTSCCPSWIKFIENNYADMLEVPSSAKSPMQMFATI
AKEIWAKEKGLQREEVTSVAIMPCVAKIYEASRVEFSVDMNYDVDYVITTRELIKIFEKSGIDLKEIEDEEIDSVMGEYT
GAGIIFGRTGGVIEAATRTAIENMTGKRIDNIEFEGLRGWDGFRICELEVGELKLRIGVAHGLKEAAKMLDKIRSGEEFF
HAIEIMACVGGCVGGGGQPKIRKNKQQVLEKRAEGLNDIDRAKVLRRSNENPEVLALYKKYLDHPLSHKAHELLHTKYFP
KVKKR

Specific function: Unknown

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=403, Percent_Identity=27.7915632754342, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI6912524, Length=401, Percent_Identity=26.6832917705736, Blast_Score=156, Evalue=6e-38,
Organism=Homo sapiens, GI134284357, Length=362, Percent_Identity=27.3480662983425, Blast_Score=153, Evalue=6e-37,
Organism=Homo sapiens, GI84452151, Length=362, Percent_Identity=27.3480662983425, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI14165461, Length=449, Percent_Identity=23.8307349665924, Blast_Score=134, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71995015, Length=418, Percent_Identity=26.7942583732057, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI116007464, Length=415, Percent_Identity=25.0602409638554, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI116007470, Length=415, Percent_Identity=25.0602409638554, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI116007466, Length=415, Percent_Identity=25.0602409638554, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI116007468, Length=415, Percent_Identity=25.0602409638554, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI116007462, Length=284, Percent_Identity=26.4084507042254, Blast_Score=112, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 72420; Mature: 72288

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCKNTTYIQSLLGSVFSTFSEDELKEITGNEKRSIAICGKINNPGIIEVPVGATLRDIL
CCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEEEECCCCCEEEECCCHHHHHHH
ELCGGVVNNSSFKAAQIGIPFGGFLNEGSLDKEFNFGLFYENISRAIIILSEEDCIIQYG
HHHCCHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHH
KFYIEYLLTKIKDGTYKNYEIVKKEITKMLKVLDRISKGVSDMRDIYILRSLAADVKDKM
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQKHNLMEEIVENFYEEIEEHIEEKKCYTAQCNHLIKLTITKKCIGCGSCKRACPVDCID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCCCCCCCCC
GELKKQHNIDYNKCTHCGACISACPVDAITAGNNTIKFLRDLATPNKVVITQMAPAIRVA
CHHHHHCCCCHHHHHHHHHHHHHCCCHHEECCCHHHHHHHHHCCCCEEEEEHHCHHHHHH
IGEAFGFEPGENVEKKIAAGLRKLGVDYVFDTTWGADLTIMEEAAELQERLEKYLAGDEN
HHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC
VKLPILTSCCPSWIKFIENNYADMLEVPSSAKSPMQMFATIAKEIWAKEKGLQREEVTSV
CCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
AIMPCVAKIYEASRVEFSVDMNYDVDYVITTRELIKIFEKSGIDLKEIEDEEIDSVMGEY
HHHHHHHHHHHHHCEEEEEECCCCCEEEEEHHHHHHHHHHCCCCHHHCCHHHHHHHHHHH
TGAGIIFGRTGGVIEAATRTAIENMTGKRIDNIEFEGLRGWDGFRICELEVGELKLRIGV
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCEEEEEEECCEEEEEEH
AHGLKEAAKMLDKIRSGEEFFHAIEIMACVGGCVGGGGQPKIRKNKQQVLEKRAEGLNDI
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHH
DRAKVLRRSNENPEVLALYKKYLDHPLSHKAHELLHTKYFPKVKKR
HHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure 
SCKNTTYIQSLLGSVFSTFSEDELKEITGNEKRSIAICGKINNPGIIEVPVGATLRDIL
CCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEEEECCCCCEEEECCCHHHHHHH
ELCGGVVNNSSFKAAQIGIPFGGFLNEGSLDKEFNFGLFYENISRAIIILSEEDCIIQYG
HHHCCHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHH
KFYIEYLLTKIKDGTYKNYEIVKKEITKMLKVLDRISKGVSDMRDIYILRSLAADVKDKM
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQKHNLMEEIVENFYEEIEEHIEEKKCYTAQCNHLIKLTITKKCIGCGSCKRACPVDCID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCCCCCCCCC
GELKKQHNIDYNKCTHCGACISACPVDAITAGNNTIKFLRDLATPNKVVITQMAPAIRVA
CHHHHHCCCCHHHHHHHHHHHHHCCCHHEECCCHHHHHHHHHCCCCEEEEEHHCHHHHHH
IGEAFGFEPGENVEKKIAAGLRKLGVDYVFDTTWGADLTIMEEAAELQERLEKYLAGDEN
HHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC
VKLPILTSCCPSWIKFIENNYADMLEVPSSAKSPMQMFATIAKEIWAKEKGLQREEVTSV
CCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
AIMPCVAKIYEASRVEFSVDMNYDVDYVITTRELIKIFEKSGIDLKEIEDEEIDSVMGEY
HHHHHHHHHHHHHCEEEEEECCCCCEEEEEHHHHHHHHHHCCCCHHHCCHHHHHHHHHHH
TGAGIIFGRTGGVIEAATRTAIENMTGKRIDNIEFEGLRGWDGFRICELEVGELKLRIGV
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCEEEEEEECCEEEEEEH
AHGLKEAAKMLDKIRSGEEFFHAIEIMACVGGCVGGGGQPKIRKNKQQVLEKRAEGLNDI
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHH
DRAKVLRRSNENPEVLALYKKYLDHPLSHKAHELLHTKYFPKVKKR
HHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]