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The map label for this gene is gmhA [H]

Identifier: 187933918

GI number: 187933918

Start: 2414212

End: 2415288

Strand: Reverse

Name: gmhA [H]

Synonym: CLL_A2335

Alternate gene names: 187933918

Gene position: 2415288-2414212 (Counterclockwise)

Preceding gene: 187935017

Following gene: 187934917

Centisome position: 63.55

GC content: 29.25

Gene sequence:

>1077_bases
ATGATAAAATTAGTGATTTTCGATATTGATGGTGTTATAACAGATGGTTCAATTATAGTAGATGAAGAAGGAAGGGAGCA
AAAAAAGATTAATTTAAAGGATATTGATGCAATTTTTGAATTGAAATCTAGAAATTATATTATCTCTGCTATAACTGGAG
AAAGTTCAAAAATAGTGACTTATTTTGAAAAAAGATTTCCATGGGATTATTTTTATTGTGGAAAGAAGAGTAAGATTGAA
ATAATAAAAGAAATTGAAAAACAAAGTAAAATAAAAGCAGAAGAAATATGTTATATAGGTGATGGAAAGTATGATATTGA
TCCTTTAAAATATGTAGGTCTTGGAGTATGCCCTAAAGATGCAATTAATAAAGCAAAAAATTCTGCTGATATAATATTAC
AAAATAGGGCAGGAGAAGGATGTTTATGGGAACTTATTTCGATTATTGAAGAATACAATAACGAGGGAGGAGCACAAAAC
TATTTTTATAAGAGACTTACAGAGCATATAGATATATTTAAAGTCATGGCATCAGATAAAGAACTTATTTATGATGTAAT
GAAAATTGGTGATAATATCATAAACTTGTTAAGTAATAAGAATCAGGTATTTTTGTGTGGAAATGGTGGAAGTGCAGCTG
ATGCACAGCATATTGCTACAGAATTTATTAGCAAATTTTACAAAGAAAGACAAGCACTTAATGCAGAAGCACTAACAGTA
AACACTTCAACATTGACAGCAGTTGGAAATGATTACAGTTTCGAGAGGATATTTGTAAGACAATTAGAAGCAAAGGCTAA
AAAAGGAGATATGCTCATAGCAATATCAACTAGTGGAAAATCTAAAAATGTATTAGAAGCATTGAGATATGGCAAAAGAG
AAGAATTAATTACAGTAATGCTAATGGGTGATTATTATAATGAAGAAGTTGAATATATATCGGATTATGTGATAAAAATT
CCATCGAAAATTACTCCACGAATACAAGAAGCGCATATATTTTTAGGCCATTTAATAGCAGAATATGCAGAACAGAAAAT
CTTTGATTGCCATGGGAATATTAGGGAATTTTTGTGA

Upstream 100 bases:

>100_bases
GTCAAAGATATTAGAGAAGTAGAAAAAATATTAGGAAATGGAGAGAAGATATTGAGTCAAGCTGAATTAGAAGTGAAAAA
AAAATTAAGAGGTTAATTAA

Downstream 100 bases:

>100_bases
AATAAATCATGGTAAGTTTAAATATTTTATCCAAAAGTGAGAAGAAAGGAAAATGTATGATTAAATTATCAGACTATGTA
TTTAAATTTATAGAAGAAAA

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MIKLVIFDIDGVITDGSIIVDEEGREQKKINLKDIDAIFELKSRNYIISAITGESSKIVTYFEKRFPWDYFYCGKKSKIE
IIKEIEKQSKIKAEEICYIGDGKYDIDPLKYVGLGVCPKDAINKAKNSADIILQNRAGEGCLWELISIIEEYNNEGGAQN
YFYKRLTEHIDIFKVMASDKELIYDVMKIGDNIINLLSNKNQVFLCGNGGSAADAQHIATEFISKFYKERQALNAEALTV
NTSTLTAVGNDYSFERIFVRQLEAKAKKGDMLIAISTSGKSKNVLEALRYGKREELITVMLMGDYYNEEVEYISDYVIKI
PSKITPRIQEAHIFLGHLIAEYAEQKIFDCHGNIREFL

Sequences:

>Translated_358_residues
MIKLVIFDIDGVITDGSIIVDEEGREQKKINLKDIDAIFELKSRNYIISAITGESSKIVTYFEKRFPWDYFYCGKKSKIE
IIKEIEKQSKIKAEEICYIGDGKYDIDPLKYVGLGVCPKDAINKAKNSADIILQNRAGEGCLWELISIIEEYNNEGGAQN
YFYKRLTEHIDIFKVMASDKELIYDVMKIGDNIINLLSNKNQVFLCGNGGSAADAQHIATEFISKFYKERQALNAEALTV
NTSTLTAVGNDYSFERIFVRQLEAKAKKGDMLIAISTSGKSKNVLEALRYGKREELITVMLMGDYYNEEVEYISDYVIKI
PSKITPRIQEAHIFLGHLIAEYAEQKIFDCHGNIREFL
>Mature_358_residues
MIKLVIFDIDGVITDGSIIVDEEGREQKKINLKDIDAIFELKSRNYIISAITGESSKIVTYFEKRFPWDYFYCGKKSKIE
IIKEIEKQSKIKAEEICYIGDGKYDIDPLKYVGLGVCPKDAINKAKNSADIILQNRAGEGCLWELISIIEEYNNEGGAQN
YFYKRLTEHIDIFKVMASDKELIYDVMKIGDNIINLLSNKNQVFLCGNGGSAADAQHIATEFISKFYKERQALNAEALTV
NTSTLTAVGNDYSFERIFVRQLEAKAKKGDMLIAISTSGKSKNVLEALRYGKREELITVMLMGDYYNEEVEYISDYVIKI
PSKITPRIQEAHIFLGHLIAEYAEQKIFDCHGNIREFL

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=176, Percent_Identity=32.3863636363636, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1786416, Length=190, Percent_Identity=30, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI2367202, Length=148, Percent_Identity=27.7027027027027, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 40755; Mature: 40755

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLVIFDIDGVITDGSIIVDEEGREQKKINLKDIDAIFELKSRNYIISAITGESSKIVT
CEEEEEEECCCEEECCEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEE
YFEKRFPWDYFYCGKKSKIEIIKEIEKQSKIKAEEICYIGDGKYDIDPLKYVGLGVCPKD
EHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCHHHEEEECCCCCCCCCHHHCCCCCCCHH
AINKAKNSADIILQNRAGEGCLWELISIIEEYNNEGGAQNYFYKRLTEHIDIFKVMASDK
HHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCH
ELIYDVMKIGDNIINLLSNKNQVFLCGNGGSAADAQHIATEFISKFYKERQALNAEALTV
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEE
NTSTLTAVGNDYSFERIFVRQLEAKAKKGDMLIAISTSGKSKNVLEALRYGKREELITVM
ECCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCHHHEEEEE
LMGDYYNEEVEYISDYVIKIPSKITPRIQEAHIFLGHLIAEYAEQKIFDCHGNIREFL
EECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
>Mature Secondary Structure
MIKLVIFDIDGVITDGSIIVDEEGREQKKINLKDIDAIFELKSRNYIISAITGESSKIVT
CEEEEEEECCCEEECCEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEE
YFEKRFPWDYFYCGKKSKIEIIKEIEKQSKIKAEEICYIGDGKYDIDPLKYVGLGVCPKD
EHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCHHHEEEECCCCCCCCCHHHCCCCCCCHH
AINKAKNSADIILQNRAGEGCLWELISIIEEYNNEGGAQNYFYKRLTEHIDIFKVMASDK
HHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCH
ELIYDVMKIGDNIINLLSNKNQVFLCGNGGSAADAQHIATEFISKFYKERQALNAEALTV
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEE
NTSTLTAVGNDYSFERIFVRQLEAKAKKGDMLIAISTSGKSKNVLEALRYGKREELITVM
ECCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCHHHEEEEE
LMGDYYNEEVEYISDYVIKIPSKITPRIQEAHIFLGHLIAEYAEQKIFDCHGNIREFL
EECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11279237; 12101286 [H]