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The map label for this gene is 187935017

Identifier: 187935017

GI number: 187935017

Start: 2415293

End: 2416117

Strand: Reverse

Name: 187935017

Synonym: CLL_A2336

Alternate gene names: NA

Gene position: 2416117-2415293 (Counterclockwise)

Preceding gene: 187932731

Following gene: 187933918

Centisome position: 63.58

GC content: 27.88

Gene sequence:

>825_bases
ATGAAAACATATATAATAGCAGAAATAGGAATTAATCATAACGGAGATATAAGAATAGCTAAAAAGCTTATCGATATAGC
AGTAATATCAGGATGTGATGCAGTTAAATTTCAAAAGAGAACAATTGATAAAGTTTATAGTAAAGAAATGCTTGATAGTC
CCCGTATAAGTCCTTGGGGAAATACTCAAAGATCACAAAAGGAAGGACTTGAATTTAATGAAAAAGAGTATGATGAGATT
AATGAATATTGTAAAACTAAAGGAATAGATTGGTTTGCATCAGCATGGGACATAGATTCACAAAAGTTTTTACAAAAATA
TGGTTTAAAATATAATAAAGTAGCTTCAGCTATACTTACTAATTATGAATTGTTAAAAGAAATTGCAAGTGAAGGAAAAT
ATACTTTTATATCAACAGGAATGAGTAATTATGAAGAAATTGATAGAGCAATAGAAGTATTTAAAAATGAAAACTGTGAA
TTTGAATTAATGCATTGTAATAGTACATATCCGATGAGAAATGAAGATGCTAATTTATCAATGATTAAGAAATTAAAAGA
AAAATATAATTGCAAAGTTGGTTATAGTGGACATGAAACAGGAGCTTTAGTTAGTATTTGTGCAGTAACTCTTGGTGCTA
CATCTATTGAGAGACATATAACTTTAGATAAAACAATGTATGGTTCAGATCAAGGAGCATCTATAGAACCATGTGAATTA
TGTAAACTAGTCAAAGATATTAGAGAAGTAGAAAAAATATTAGGAAATGGAGAGAAGATATTGAGTCAAGCTGAATTAGA
AGTGAAAAAAAAATTAAGAGGTTAA

Upstream 100 bases:

>100_bases
ATTATTCAAAGGATAATATAAACGAATTAATGAAAAATCAAATAAATGGATATTTTAAAGAATTTTTATAAATATATATA
GAGAGGTAGGATTATATAAA

Downstream 100 bases:

>100_bases
TTAAATGATAAAATTAGTGATTTTCGATATTGATGGTGTTATAACAGATGGTTCAATTATAGTAGATGAAGAAGGAAGGG
AGCAAAAAAAGATTAATTTA

Product: sialic acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MKTYIIAEIGINHNGDIRIAKKLIDIAVISGCDAVKFQKRTIDKVYSKEMLDSPRISPWGNTQRSQKEGLEFNEKEYDEI
NEYCKTKGIDWFASAWDIDSQKFLQKYGLKYNKVASAILTNYELLKEIASEGKYTFISTGMSNYEEIDRAIEVFKNENCE
FELMHCNSTYPMRNEDANLSMIKKLKEKYNCKVGYSGHETGALVSICAVTLGATSIERHITLDKTMYGSDQGASIEPCEL
CKLVKDIREVEKILGNGEKILSQAELEVKKKLRG

Sequences:

>Translated_274_residues
MKTYIIAEIGINHNGDIRIAKKLIDIAVISGCDAVKFQKRTIDKVYSKEMLDSPRISPWGNTQRSQKEGLEFNEKEYDEI
NEYCKTKGIDWFASAWDIDSQKFLQKYGLKYNKVASAILTNYELLKEIASEGKYTFISTGMSNYEEIDRAIEVFKNENCE
FELMHCNSTYPMRNEDANLSMIKKLKEKYNCKVGYSGHETGALVSICAVTLGATSIERHITLDKTMYGSDQGASIEPCEL
CKLVKDIREVEKILGNGEKILSQAELEVKKKLRG
>Mature_274_residues
MKTYIIAEIGINHNGDIRIAKKLIDIAVISGCDAVKFQKRTIDKVYSKEMLDSPRISPWGNTQRSQKEGLEFNEKEYDEI
NEYCKTKGIDWFASAWDIDSQKFLQKYGLKYNKVASAILTNYELLKEIASEGKYTFISTGMSNYEEIDRAIEVFKNENCE
FELMHCNSTYPMRNEDANLSMIKKLKEKYNCKVGYSGHETGALVSICAVTLGATSIERHITLDKTMYGSDQGASIEPCEL
CKLVKDIREVEKILGNGEKILSQAELEVKKKLRG

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=272, Percent_Identity=39.3382352941176, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI21357081, Length=249, Percent_Identity=40.5622489959839, Blast_Score=181, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 31165; Mature: 31165

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYIIAEIGINHNGDIRIAKKLIDIAVISGCDAVKFQKRTIDKVYSKEMLDSPRISPWG
CCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
NTQRSQKEGLEFNEKEYDEINEYCKTKGIDWFASAWDIDSQKFLQKYGLKYNKVASAILT
CCCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHCCCHHHHHHHHHH
NYELLKEIASEGKYTFISTGMSNYEEIDRAIEVFKNENCEFELMHCNSTYPMRNEDANLS
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHH
MIKKLKEKYNCKVGYSGHETGALVSICAVTLGATSIERHITLDKTMYGSDQGASIEPCEL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHEEECHHCCCCCCCCCCCHHHH
CKLVKDIREVEKILGNGEKILSQAELEVKKKLRG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTYIIAEIGINHNGDIRIAKKLIDIAVISGCDAVKFQKRTIDKVYSKEMLDSPRISPWG
CCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
NTQRSQKEGLEFNEKEYDEINEYCKTKGIDWFASAWDIDSQKFLQKYGLKYNKVASAILT
CCCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHCCCHHHHHHHHHH
NYELLKEIASEGKYTFISTGMSNYEEIDRAIEVFKNENCEFELMHCNSTYPMRNEDANLS
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHH
MIKKLKEKYNCKVGYSGHETGALVSICAVTLGATSIERHITLDKTMYGSDQGASIEPCEL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHEEECHHCCCCCCCCCCCHHHH
CKLVKDIREVEKILGNGEKILSQAELEVKKKLRG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]