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The map label for this gene is crp [C]

Identifier: 187933353

GI number: 187933353

Start: 3143113

End: 3143805

Strand: Reverse

Name: crp [C]

Synonym: CLL_A3043

Alternate gene names: 187933353

Gene position: 3143805-3143113 (Counterclockwise)

Preceding gene: 187935080

Following gene: 187934292

Centisome position: 82.72

GC content: 25.97

Gene sequence:

>693_bases
ATGAATAATGTTACCATGCAGGAACTTAGGAATTTAGAAATCTTTAAAAATATATGTGATGATTCTTTGAACAAAATTAT
TGAAATGGGAATTTTAATTAAGTACCCTTCAGGTAGGCATATTTTTAGAGACAAAGAAGATGTGAAAATTTTATATGTAA
TATTAAGTGGTACAGTATCATTGTATAAATTAAATGAATGTGGGCATAAAAGAGCTATCTTTATTTTAGGTAAAGGAAAA
ATGATTAATGATGTTATAATACAGGATTTGCCATCATCCATTAATTGCGAGGTTTTTGAAGATGCAGAAATTTTAAGTTT
TGATAAAGAAGATTTTATGAAAATTATGGAGTTAGATTTTATATTAACAAAAAATGTAATGTGCTCATTATCGATGAAAG
TAAGAAGATTGTATAGGCAGATTAAAAATTCAACAGGTGTTATAAAAATGGAAAAACGATTATGTGCAAAGCTGTGGAAA
TTAAGCAAGGATTATGGAAGTGAAAAAAATGGTGAAGTAGTAGTTGATAAAAAGATAACTATTACCTATTTAGCAGACTT
ATTAGGTTCAAAAAGAGAAACAATATCCAGAGCATTAAAAGTATTATGTAATGAAAATTTAATTGAATATAAAAATAAGC
AGATAATAGTAAAAAATCAGAAAAAACTATCTGAATTTTTTAAAGCACCGTGA

Upstream 100 bases:

>100_bases
ATTTAAGAGATACAGGTAAGATTCTTGCCGAAACTTAAAAGTTAGCTTTAAGCTAAAGTATATATGAAATATTATTTAGA
AGATATATTTTGGAGGAATT

Downstream 100 bases:

>100_bases
TTAATATCACGGTGCTTTAATTATTTAAAATATATACTTAGATTAATAGAAATTATAATTTAAAATTGAAATTATGAAGG
GAGACTTAATACGATGTTTT

Product: transcriptional regulator, Crp/Fnr family

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Transcription Regulator; Transcriptional Regulator; Crp Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Cyclic AMP Receptor Protein; CRP Family Transcriptional Regulator; Catabolite Gene Activator; FNR-Like Catabolite Gene Activator Protein

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MNNVTMQELRNLEIFKNICDDSLNKIIEMGILIKYPSGRHIFRDKEDVKILYVILSGTVSLYKLNECGHKRAIFILGKGK
MINDVIIQDLPSSINCEVFEDAEILSFDKEDFMKIMELDFILTKNVMCSLSMKVRRLYRQIKNSTGVIKMEKRLCAKLWK
LSKDYGSEKNGEVVVDKKITITYLADLLGSKRETISRALKVLCNENLIEYKNKQIIVKNQKKLSEFFKAP

Sequences:

>Translated_230_residues
MNNVTMQELRNLEIFKNICDDSLNKIIEMGILIKYPSGRHIFRDKEDVKILYVILSGTVSLYKLNECGHKRAIFILGKGK
MINDVIIQDLPSSINCEVFEDAEILSFDKEDFMKIMELDFILTKNVMCSLSMKVRRLYRQIKNSTGVIKMEKRLCAKLWK
LSKDYGSEKNGEVVVDKKITITYLADLLGSKRETISRALKVLCNENLIEYKNKQIIVKNQKKLSEFFKAP
>Mature_230_residues
MNNVTMQELRNLEIFKNICDDSLNKIIEMGILIKYPSGRHIFRDKEDVKILYVILSGTVSLYKLNECGHKRAIFILGKGK
MINDVIIQDLPSSINCEVFEDAEILSFDKEDFMKIMELDFILTKNVMCSLSMKVRRLYRQIKNSTGVIKMEKRLCAKLWK
LSKDYGSEKNGEVVVDKKITITYLADLLGSKRETISRALKVLCNENLIEYKNKQIIVKNQKKLSEFFKAP

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 26657; Mature: 26657

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNVTMQELRNLEIFKNICDDSLNKIIEMGILIKYPSGRHIFRDKEDVKILYVILSGTVS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCEEEEEEEECCEE
LYKLNECGHKRAIFILGKGKMINDVIIQDLPSSINCEVFEDAEILSFDKEDFMKIMELDF
EEEECCCCCCEEEEEEECCCHHHHHHHHHCCCCCCCEEECCCHHHCCCHHHHHHHHHHHH
ILTKNVMCSLSMKVRRLYRQIKNSTGVIKMEKRLCAKLWKLSKDYGSEKNGEVVVDKKIT
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCEEEECCHH
ITYLADLLGSKRETISRALKVLCNENLIEYKNKQIIVKNQKKLSEFFKAP
HHHHHHHHCCHHHHHHHHHHHHHCCCHHHHCCCEEEEECHHHHHHHHCCC
>Mature Secondary Structure
MNNVTMQELRNLEIFKNICDDSLNKIIEMGILIKYPSGRHIFRDKEDVKILYVILSGTVS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCEEEEEEEECCEE
LYKLNECGHKRAIFILGKGKMINDVIIQDLPSSINCEVFEDAEILSFDKEDFMKIMELDF
EEEECCCCCCEEEEEEECCCHHHHHHHHHCCCCCCCEEECCCHHHCCCHHHHHHHHHHHH
ILTKNVMCSLSMKVRRLYRQIKNSTGVIKMEKRLCAKLWKLSKDYGSEKNGEVVVDKKIT
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCEEEECCHH
ITYLADLLGSKRETISRALKVLCNENLIEYKNKQIIVKNQKKLSEFFKAP
HHHHHHHHCCHHHHHHHHHHHHHCCCHHHHCCCEEEEECHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA