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The map label for this gene is nirC [H]

Identifier: 187934292

GI number: 187934292

Start: 3142252

End: 3143019

Strand: Reverse

Name: nirC [H]

Synonym: CLL_A3042

Alternate gene names: 187934292

Gene position: 3143019-3142252 (Counterclockwise)

Preceding gene: 187933353

Following gene: 187935283

Centisome position: 82.7

GC content: 30.86

Gene sequence:

>768_bases
ATGTTTTGTGAAGAATTTAACAGTGTAGTAGGGGCTGCAAAAGCAAAGATTAATTTACTAAAAACTAATAAATTAGGTTA
TTTTATTAGTTCAATGCTTGCAGGTGCTTATGTAGGAATGGGAATAATACTTATATTTACAATAGGTGGGTTTTTAAGTA
ATGCAGAATCACCATTTACTAAAATAATTATGGGAGCATCTTTTGGAGTAGCACTTAGTTTAGTAGTAATGGCAGGATCA
GAACTTTTTACAGGAAATAATTTTGTTATGACAGCAGGTTCTTTAAGTGGTGAAGTAACATGGAGTGATACATTTAAAGT
TTGGGGACTTTGCTTTTTTGGAAATTTAGTTGGTTCTATAATTTTAGGTATTATGTTTTACTTAACAGGTCTTGCAACAG
GTCCAGTAGGAGAATTTATTGCTAATACCTCAGCAGTAAAAATGAGTGTGCCTTTTTTACCATTATTAATGAGAGGTGTG
CTTTGTAATATACTAGTTTGTTTAGCTGTATGGTGTAGTTTCCGTTGTAAAAATGAAGTTGCTAAGTTAATTATGATATT
TTGGTGTTTATTTGTGTTTATAACAGCTGGATTTGAACATAGTGTGGCTAATATGACACTTTTAACAGTAGGATTACTTT
CACCAGGTGTAGCTAATGTAAGTATAATGGGATATTTATATAACATCATAGTTGTAACACTTGGAAATATCATTGGAGGA
GCTATATTTTTAGCGGTTCCATACTATTTAATATCAAAAAAGAAATAA

Upstream 100 bases:

>100_bases
ACCGTGATTAATATCACGGTGCTTTAATTATTTAAAATATATACTTAGATTAATAGAAATTATAATTTAAAATTGAAATT
ATGAAGGGAGACTTAATACG

Downstream 100 bases:

>100_bases
GGAGGATAATATTATGGGATATAAATTAAAGAAAACTGATGTAAACAATATATTTGATAACTTATTAACAGAATATGATA
TATATGCACCTAAGTTATTT

Product: formate/nitrite family of transporter

Products: Proton [Cytoplasm]; nitrite [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MFCEEFNSVVGAAKAKINLLKTNKLGYFISSMLAGAYVGMGIILIFTIGGFLSNAESPFTKIIMGASFGVALSLVVMAGS
ELFTGNNFVMTAGSLSGEVTWSDTFKVWGLCFFGNLVGSIILGIMFYLTGLATGPVGEFIANTSAVKMSVPFLPLLMRGV
LCNILVCLAVWCSFRCKNEVAKLIMIFWCLFVFITAGFEHSVANMTLLTVGLLSPGVANVSIMGYLYNIIVVTLGNIIGG
AIFLAVPYYLISKKK

Sequences:

>Translated_255_residues
MFCEEFNSVVGAAKAKINLLKTNKLGYFISSMLAGAYVGMGIILIFTIGGFLSNAESPFTKIIMGASFGVALSLVVMAGS
ELFTGNNFVMTAGSLSGEVTWSDTFKVWGLCFFGNLVGSIILGIMFYLTGLATGPVGEFIANTSAVKMSVPFLPLLMRGV
LCNILVCLAVWCSFRCKNEVAKLIMIFWCLFVFITAGFEHSVANMTLLTVGLLSPGVANVSIMGYLYNIIVVTLGNIIGG
AIFLAVPYYLISKKK
>Mature_255_residues
MFCEEFNSVVGAAKAKINLLKTNKLGYFISSMLAGAYVGMGIILIFTIGGFLSNAESPFTKIIMGASFGVALSLVVMAGS
ELFTGNNFVMTAGSLSGEVTWSDTFKVWGLCFFGNLVGSIILGIMFYLTGLATGPVGEFIANTSAVKMSVPFLPLLMRGV
LCNILVCLAVWCSFRCKNEVAKLIMIFWCLFVFITAGFEHSVANMTLLTVGLLSPGVANVSIMGYLYNIIVVTLGNIIGG
AIFLAVPYYLISKKK

Specific function: May act as a nitrite transporter [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI87082249, Length=255, Percent_Identity=39.6078431372549, Blast_Score=184, Evalue=4e-48,
Organism=Escherichia coli, GI1787132, Length=267, Percent_Identity=30.3370786516854, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788837, Length=277, Percent_Identity=23.826714801444, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321779, Length=232, Percent_Identity=30.6034482758621, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 27286; Mature: 27286

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS01005 FORMATE_NITRITE_TP_1 ; PS01006 FORMATE_NITRITE_TP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFCEEFNSVVGAAKAKINLLKTNKLGYFISSMLAGAYVGMGIILIFTIGGFLSNAESPFT
CCHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
KIIMGASFGVALSLVVMAGSELFTGNNFVMTAGSLSGEVTWSDTFKVWGLCFFGNLVGSI
HHHHCCCHHHHHHHHHHHCCCEEECCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHH
ILGIMFYLTGLATGPVGEFIANTSAVKMSVPFLPLLMRGVLCNILVCLAVWCSFRCKNEV
HHHHHHHHHHCCCCCHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKLIMIFWCLFVFITAGFEHSVANMTLLTVGLLSPGVANVSIMGYLYNIIVVTLGNIIGG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
AIFLAVPYYLISKKK
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MFCEEFNSVVGAAKAKINLLKTNKLGYFISSMLAGAYVGMGIILIFTIGGFLSNAESPFT
CCHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
KIIMGASFGVALSLVVMAGSELFTGNNFVMTAGSLSGEVTWSDTFKVWGLCFFGNLVGSI
HHHHCCCHHHHHHHHHHHCCCEEECCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHH
ILGIMFYLTGLATGPVGEFIANTSAVKMSVPFLPLLMRGVLCNILVCLAVWCSFRCKNEV
HHHHHHHHHHCCCCCHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKLIMIFWCLFVFITAGFEHSVANMTLLTVGLLSPGVANVSIMGYLYNIIVVTLGNIIGG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
AIFLAVPYYLISKKK
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; nitrite [Periplasm] [C]

Specific reaction: Proton [Periplasm] + nitrite [Periplasm] = Proton [Cytoplasm] + nitrite [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1987123; 11677609 [H]