Click here to switch to the map view.

The map label for this gene is rfbG [H]

Identifier: 187932731

GI number: 187932731

Start: 2416147

End: 2417199

Strand: Reverse

Name: rfbG [H]

Synonym: CLL_A2337

Alternate gene names: 187932731

Gene position: 2417199-2416147 (Counterclockwise)

Preceding gene: 187935021

Following gene: 187935017

Centisome position: 63.61

GC content: 28.4

Gene sequence:

>1053_bases
ATGCTTGAGTTTTATAATCAAAAAAGGGTTTTTATAACAGGACATACTGGATTTAAAGGAAGTTGGCTTACCAAGATTTT
AATTATGGCAGGAGCTAAAGTTACTGGATTTTCATTAATATCTAATACAAATCCTTCTTTATTCAATATTATTAATATAA
AAGAGGATATCAATTCAATTATTGGAGATATAAGAGATTTAGAGCATTTAAAAAAAGAATTATGCAATTGCAAACCAGAT
ATTGTATTTCATTTAGCGGCACAACCTTTAGTTAGAGAATCATATAAAAATCCAGTATACACATATGAGACAAATGTAAT
GGGAACTGTAAATTTGCTTGAAAGCATAAGAAATTGTAAAAGTGTACGTTCGGTAGTTATTATCACAACAGATAAGGTTT
ATAAAAATAATGAATGGGATTGGGGGTATCGTGAAATTGATCCATTAGATGGTTTTGATCCTTATTCTAATAGTAAATCT
TGTTCTGAACTTGTTATTCGTAGTTATAAAAATTCTTTCTTTTCAGATCAAGAATCAGCTATATCTACAGCCAGGGCTGG
TAATGTAATAGGTGGTGGTGATTTCTCAGAAGATAGAATAATCCCAGATTGTATTAGAGCAGCTATTAAGAAAGAAGATA
TTGTTGTTAGAAATCCAAAATCTATTAGACCTTATCAACACGTCTTTGAAGCACTTTTAGGATATTTGTTGATTGCAGAA
AAGCAATACAATCATAAGTATTTTGAAGGAAGTTATAACATAGGACCAAATGAAGGTGGATGTGTCACTACAGCTAATCT
TGTTGAAACATTTTGTAACTTATGGGGAAATATGAAATGGATAAGTAATATAGAAAATACTCATTTTTATGAATCAAACC
TTTTGAAGCTAGATTGTTCAAAAATAAAAAATAAACTTGGATGGAAGCCTAAATTAAGTATAAAAGAGGCTGTTGATTTA
ACTATAGAATGGACAAAATGTTATTATTCAAAGGATAATATAAACGAATTAATGAAAAATCAAATAAATGGATATTTTAA
AGAATTTTTATAA

Upstream 100 bases:

>100_bases
AGCATAGTGGATTTTGGAAATGTATGGATACTCAAAGAGATAAAGAATTACTTGAAAAACTATGGAGAGAAAATAATGCT
AAATGGAAGGTATGGGATTA

Downstream 100 bases:

>100_bases
ATATATATAGAGAGGTAGGATTATATAAAATGAAAACATATATAATAGCAGAAATAGGAATTAATCATAACGGAGATATA
AGAATAGCTAAAAAGCTTAT

Product: CDP-glucose 4,6-dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MLEFYNQKRVFITGHTGFKGSWLTKILIMAGAKVTGFSLISNTNPSLFNIINIKEDINSIIGDIRDLEHLKKELCNCKPD
IVFHLAAQPLVRESYKNPVYTYETNVMGTVNLLESIRNCKSVRSVVIITTDKVYKNNEWDWGYREIDPLDGFDPYSNSKS
CSELVIRSYKNSFFSDQESAISTARAGNVIGGGDFSEDRIIPDCIRAAIKKEDIVVRNPKSIRPYQHVFEALLGYLLIAE
KQYNHKYFEGSYNIGPNEGGCVTTANLVETFCNLWGNMKWISNIENTHFYESNLLKLDCSKIKNKLGWKPKLSIKEAVDL
TIEWTKCYYSKDNINELMKNQINGYFKEFL

Sequences:

>Translated_350_residues
MLEFYNQKRVFITGHTGFKGSWLTKILIMAGAKVTGFSLISNTNPSLFNIINIKEDINSIIGDIRDLEHLKKELCNCKPD
IVFHLAAQPLVRESYKNPVYTYETNVMGTVNLLESIRNCKSVRSVVIITTDKVYKNNEWDWGYREIDPLDGFDPYSNSKS
CSELVIRSYKNSFFSDQESAISTARAGNVIGGGDFSEDRIIPDCIRAAIKKEDIVVRNPKSIRPYQHVFEALLGYLLIAE
KQYNHKYFEGSYNIGPNEGGCVTTANLVETFCNLWGNMKWISNIENTHFYESNLLKLDCSKIKNKLGWKPKLSIKEAVDL
TIEWTKCYYSKDNINELMKNQINGYFKEFL
>Mature_350_residues
MLEFYNQKRVFITGHTGFKGSWLTKILIMAGAKVTGFSLISNTNPSLFNIINIKEDINSIIGDIRDLEHLKKELCNCKPD
IVFHLAAQPLVRESYKNPVYTYETNVMGTVNLLESIRNCKSVRSVVIITTDKVYKNNEWDWGYREIDPLDGFDPYSNSKS
CSELVIRSYKNSFFSDQESAISTARAGNVIGGGDFSEDRIIPDCIRAAIKKEDIVVRNPKSIRPYQHVFEALLGYLLIAE
KQYNHKYFEGSYNIGPNEGGCVTTANLVETFCNLWGNMKWISNIENTHFYESNLLKLDCSKIKNKLGWKPKLSIKEAVDL
TIEWTKCYYSKDNINELMKNQINGYFKEFL

Specific function: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE O-SIDE CHAINS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI42516563, Length=330, Percent_Identity=24.2424242424242, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI7657641, Length=328, Percent_Identity=26.219512195122, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI48994969, Length=343, Percent_Identity=26.530612244898, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788353, Length=352, Percent_Identity=24.1477272727273, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786974, Length=341, Percent_Identity=24.633431085044, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17507723, Length=364, Percent_Identity=21.978021978022, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115532424, Length=335, Percent_Identity=24.4776119402985, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI133901786, Length=187, Percent_Identity=27.807486631016, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI133901788, Length=187, Percent_Identity=27.807486631016, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI133901790, Length=187, Percent_Identity=27.807486631016, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17539422, Length=187, Percent_Identity=27.807486631016, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17539424, Length=187, Percent_Identity=27.807486631016, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356223, Length=335, Percent_Identity=24.7761194029851, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013445
- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =4.2.1.45 [H]

Molecular weight: Translated: 40139; Mature: 40139

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEFYNQKRVFITGHTGFKGSWLTKILIMAGAKVTGFSLISNTNPSLFNIINIKEDINSI
CCCEECCCEEEEEECCCCCHHHHHHHHHHHCCCEECEEEECCCCCCEEEEEECHHHHHHH
IGDIRDLEHLKKELCNCKPDIVFHLAAQPLVRESYKNPVYTYETNVMGTVNLLESIRNCK
HHHHHHHHHHHHHHHCCCCCEEEEEHHCHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHH
SVRSVVIITTDKVYKNNEWDWGYREIDPLDGFDPYSNSKSCSELVIRSYKNSFFSDQESA
HHCEEEEEEECCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
ISTARAGNVIGGGDFSEDRIIPDCIRAAIKKEDIVVRNPKSIRPYQHVFEALLGYLLIAE
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHH
KQYNHKYFEGSYNIGPNEGGCVTTANLVETFCNLWGNMKWISNIENTHFYESNLLKLDCS
HHCCCCEECCCCCCCCCCCCCEEHHHHHHHHHHHHCCCHHHHCCCCCEEECCCEEEEEHH
KIKNKLGWKPKLSIKEAVDLTIEWTKCYYSKDNINELMKNQINGYFKEFL
HHHHHCCCCCCCCHHHHHEEEEEEHEEECCCCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLEFYNQKRVFITGHTGFKGSWLTKILIMAGAKVTGFSLISNTNPSLFNIINIKEDINSI
CCCEECCCEEEEEECCCCCHHHHHHHHHHHCCCEECEEEECCCCCCEEEEEECHHHHHHH
IGDIRDLEHLKKELCNCKPDIVFHLAAQPLVRESYKNPVYTYETNVMGTVNLLESIRNCK
HHHHHHHHHHHHHHHCCCCCEEEEEHHCHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHH
SVRSVVIITTDKVYKNNEWDWGYREIDPLDGFDPYSNSKSCSELVIRSYKNSFFSDQESA
HHCEEEEEEECCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
ISTARAGNVIGGGDFSEDRIIPDCIRAAIKKEDIVVRNPKSIRPYQHVFEALLGYLLIAE
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHH
KQYNHKYFEGSYNIGPNEGGCVTTANLVETFCNLWGNMKWISNIENTHFYESNLLKLDCS
HHCCCCEECCCCCCCCCCCCCEEHHHHHHHHHHHHCCCHHHHCCCCCEEECCCEEEEEHH
KIKNKLGWKPKLSIKEAVDLTIEWTKCYYSKDNINELMKNQINGYFKEFL
HHHHHCCCCCCCCHHHHHEEEEEEHEEECCCCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609 [H]