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The map label for this gene is nahA [H]

Identifier: 187736625

GI number: 187736625

Start: 2615083

End: 2616732

Strand: Reverse

Name: nahA [H]

Synonym: Amuc_2148

Alternate gene names: 187736625

Gene position: 2616732-2615083 (Counterclockwise)

Preceding gene: 187736626

Following gene: 187736624

Centisome position: 98.22

GC content: 59.52

Gene sequence:

>1650_bases
ATGATGAATAAGGGGTGTTGTTTCCGTCTGGCAGCATGGCTGGCCCTGTCCGGATTACCGGGCGCCGGCATGGCGGAAAT
GCTGCCGGCCGAGGAGGTGCTGCTCCCCGCGCCTTCCGCATGCAGGTCTGACCGGGCCGCCGTGGCGCATCTCCCGTTGC
GGCTGGCGGTCTATGCGCCGGAAAAGGATGTTCCTGTAGTGGAAGCTCTCCTGAATGTGCTCAATGCCCAGGGCGTTTTG
TCCGGCCTCTCCATAACCCGTGACAAAGCCTCTGCGGATGCCGTCTGTTCGGTTGAGGGAACCCCCTCGGGGACAGGCGA
AGGATATGAGGCCCGCCTGAAGCGTGACGTGGAAGGGAGGGGCATCCTGCATCTGAAAGCGGCGGCGCCCCAGGGCCTTT
TCTACGCGTGGCAGAGCATGGTCCAGATTTTAAGCGCCAACCGGACCGGGGAGGGGTTTTCCGTACCCGTTTTTTCCCTC
CGGGATGATCCCCGCTTTGAATGGCGGGGCCTGATGCTGGATGTTTCCCGCCACTTCTTTACCATGGCGGAAGTCAAGCG
CATGGTTGACACCATGTCCCTGTTCAAGCTTAACCGCCTCCACCTGCACCTGACGGACGGTCCCGGCTGGCGCCTGGAAA
TTAAAAAATATCCATTGCTTACCTCCATGAGCGCCTGGCGCGTTCCGCTCGCTGACGGAGAATGGAACTGGCAGGAAGTG
AAACTCGCCATCCAGGAGCATGACCCGGAAGCTACCTATGGCGGTTTTTACACCCAGGAGCAGATGAAGGAGATTATTGA
CTATGCGCGCAGCCGCCAGGTTACCGTTGTTCCGGAAATAGACCTTCCCGGCCATTCCTATGCGGCCATGCATGCCTACG
GGGATTTGATTTGCGACGGTGTGGATTTTCCCGTGGAGGGGAAAAAAGGACGGGATGCCGTCTGCATGGGGCGCCCGGAA
ACGCTCCGCTTCGTGAAAGACGTAGTGGATGAACTCAAGGCCGTTTTTCCGCCCGGCTCCCCTATCCATTTGGGCCATGA
CGAGGTGTCTGCCGAGGCATGGAAAAAATGCCGGTATTGCCAGAACCGTTTAAAGAACCTGAGGGAGAAGGATCTCAAGG
CCCTGGGCCGGGATTTCCTGCAGCAGATTGCGGACTACGTGCGGAAGGACGGTTATGACGCCATCGTCTGGGATGAAGCC
GGGGAACTGGAGGCGGACAAACACATCCTCGTTATGGCGTGGCGCGGCAACGGCTTTGCTGCGGCGGCAGCCAGGAAAGG
GCATCCCGTCATTCTGGCGCCGTGTTCCCACTTCTATTTTGACTATTACCAGTCTGCCGCATCCACGGAGCCGAAAGCCG
TCGGGGGCCTTATTCCGCTCAAGCAGGTGTACGGCTATGAATTGCCGGAACTCTCCCCGGAGGAAGCCGCCAGGGTGCGC
GGCCTTCAGGCTAACATCTGGACGGAATACCTGTACAATATGGGGCTGGTGGAATACATGGCATGGCCGCGCGCCCTGGC
CCTGTCCGAACGCGCCTGGAGCGACTGCGACCCCCGGGACTACAAATCCTTCCGCAGCCGTGCCTCCAGGGCCCTGAAAA
TCCTGGAAAAACTGGCCGTGAAATACCGCCCCATGGATGAAGAAGACTAG

Upstream 100 bases:

>100_bases
GCGGCTGAATATGGCCGCGCCTTTGCCTTCCGGGACACAGGGGTCTGAGGGAAAGCTCCTTCCATTGAAAGAAGAGACCA
GGGTGGGCCGTACTTCCGGG

Downstream 100 bases:

>100_bases
GAATTCCCGCCTTGGCTCTTTCTGCCCGGCAGGAGAGCCCCAGCCCGGGATTTTCACCCGCAGGTTTTATTGACAGCTGG
TGCCGGGCCATGATAAAAAC

Product: Beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MMNKGCCFRLAAWLALSGLPGAGMAEMLPAEEVLLPAPSACRSDRAAVAHLPLRLAVYAPEKDVPVVEALLNVLNAQGVL
SGLSITRDKASADAVCSVEGTPSGTGEGYEARLKRDVEGRGILHLKAAAPQGLFYAWQSMVQILSANRTGEGFSVPVFSL
RDDPRFEWRGLMLDVSRHFFTMAEVKRMVDTMSLFKLNRLHLHLTDGPGWRLEIKKYPLLTSMSAWRVPLADGEWNWQEV
KLAIQEHDPEATYGGFYTQEQMKEIIDYARSRQVTVVPEIDLPGHSYAAMHAYGDLICDGVDFPVEGKKGRDAVCMGRPE
TLRFVKDVVDELKAVFPPGSPIHLGHDEVSAEAWKKCRYCQNRLKNLREKDLKALGRDFLQQIADYVRKDGYDAIVWDEA
GELEADKHILVMAWRGNGFAAAAARKGHPVILAPCSHFYFDYYQSAASTEPKAVGGLIPLKQVYGYELPELSPEEAARVR
GLQANIWTEYLYNMGLVEYMAWPRALALSERAWSDCDPRDYKSFRSRASRALKILEKLAVKYRPMDEED

Sequences:

>Translated_549_residues
MMNKGCCFRLAAWLALSGLPGAGMAEMLPAEEVLLPAPSACRSDRAAVAHLPLRLAVYAPEKDVPVVEALLNVLNAQGVL
SGLSITRDKASADAVCSVEGTPSGTGEGYEARLKRDVEGRGILHLKAAAPQGLFYAWQSMVQILSANRTGEGFSVPVFSL
RDDPRFEWRGLMLDVSRHFFTMAEVKRMVDTMSLFKLNRLHLHLTDGPGWRLEIKKYPLLTSMSAWRVPLADGEWNWQEV
KLAIQEHDPEATYGGFYTQEQMKEIIDYARSRQVTVVPEIDLPGHSYAAMHAYGDLICDGVDFPVEGKKGRDAVCMGRPE
TLRFVKDVVDELKAVFPPGSPIHLGHDEVSAEAWKKCRYCQNRLKNLREKDLKALGRDFLQQIADYVRKDGYDAIVWDEA
GELEADKHILVMAWRGNGFAAAAARKGHPVILAPCSHFYFDYYQSAASTEPKAVGGLIPLKQVYGYELPELSPEEAARVR
GLQANIWTEYLYNMGLVEYMAWPRALALSERAWSDCDPRDYKSFRSRASRALKILEKLAVKYRPMDEED
>Mature_549_residues
MMNKGCCFRLAAWLALSGLPGAGMAEMLPAEEVLLPAPSACRSDRAAVAHLPLRLAVYAPEKDVPVVEALLNVLNAQGVL
SGLSITRDKASADAVCSVEGTPSGTGEGYEARLKRDVEGRGILHLKAAAPQGLFYAWQSMVQILSANRTGEGFSVPVFSL
RDDPRFEWRGLMLDVSRHFFTMAEVKRMVDTMSLFKLNRLHLHLTDGPGWRLEIKKYPLLTSMSAWRVPLADGEWNWQEV
KLAIQEHDPEATYGGFYTQEQMKEIIDYARSRQVTVVPEIDLPGHSYAAMHAYGDLICDGVDFPVEGKKGRDAVCMGRPE
TLRFVKDVVDELKAVFPPGSPIHLGHDEVSAEAWKKCRYCQNRLKNLREKDLKALGRDFLQQIADYVRKDGYDAIVWDEA
GELEADKHILVMAWRGNGFAAAAARKGHPVILAPCSHFYFDYYQSAASTEPKAVGGLIPLKQVYGYELPELSPEEAARVR
GLQANIWTEYLYNMGLVEYMAWPRALALSERAWSDCDPRDYKSFRSRASRALKILEKLAVKYRPMDEED

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=425, Percent_Identity=25.6470588235294, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI189181666, Length=416, Percent_Identity=28.125, Blast_Score=119, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17569815, Length=414, Percent_Identity=26.0869565217391, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24657468, Length=434, Percent_Identity=23.7327188940092, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI17647501, Length=434, Percent_Identity=23.7327188940092, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281365639, Length=434, Percent_Identity=23.7327188940092, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24657474, Length=434, Percent_Identity=23.7327188940092, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24653074, Length=389, Percent_Identity=25.1928020565553, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI45551090, Length=389, Percent_Identity=25.1928020565553, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI17933586, Length=455, Percent_Identity=20.2197802197802, Blast_Score=88, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 61476; Mature: 61476

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNKGCCFRLAAWLALSGLPGAGMAEMLPAEEVLLPAPSACRSDRAAVAHLPLRLAVYAP
CCCCCHHHHHHHHHHHCCCCCCCHHHHCCHHHHCCCCCHHHCCCCCEEEECCEEEEEECC
EKDVPVVEALLNVLNAQGVLSGLSITRDKASADAVCSVEGTPSGTGEGYEARLKRDVEGR
CCCCHHHHHHHHHHHHHHHHHCCEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCC
GILHLKAAAPQGLFYAWQSMVQILSANRTGEGFSVPVFSLRDDPRFEWRGLMLDVSRHFF
CEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHH
TMAEVKRMVDTMSLFKLNRLHLHLTDGPGWRLEIKKYPLLTSMSAWRVPLADGEWNWQEV
HHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEEEECCCCEECCCCCEEECCCCCCCHHHH
KLAIQEHDPEATYGGFYTQEQMKEIIDYARSRQVTVVPEIDLPGHSYAAMHAYGDLICDG
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCC
VDFPVEGKKGRDAVCMGRPETLRFVKDVVDELKAVFPPGSPIHLGHDEVSAEAWKKCRYC
CCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHH
QNRLKNLREKDLKALGRDFLQQIADYVRKDGYDAIVWDEAGELEADKHILVMAWRGNGFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECCCCEE
AAAARKGHPVILAPCSHFYFDYYQSAASTEPKAVGGLIPLKQVYGYELPELSPEEAARVR
EECCCCCCCEEEECHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHCCCCCCCCHHHHHHHC
GLQANIWTEYLYNMGLVEYMAWPRALALSERAWSDCDPRDYKSFRSRASRALKILEKLAV
CCHHHHHHHHHHHCCHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KYRPMDEED
HCCCCCCCC
>Mature Secondary Structure
MMNKGCCFRLAAWLALSGLPGAGMAEMLPAEEVLLPAPSACRSDRAAVAHLPLRLAVYAP
CCCCCHHHHHHHHHHHCCCCCCCHHHHCCHHHHCCCCCHHHCCCCCEEEECCEEEEEECC
EKDVPVVEALLNVLNAQGVLSGLSITRDKASADAVCSVEGTPSGTGEGYEARLKRDVEGR
CCCCHHHHHHHHHHHHHHHHHCCEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCC
GILHLKAAAPQGLFYAWQSMVQILSANRTGEGFSVPVFSLRDDPRFEWRGLMLDVSRHFF
CEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHH
TMAEVKRMVDTMSLFKLNRLHLHLTDGPGWRLEIKKYPLLTSMSAWRVPLADGEWNWQEV
HHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEEEECCCCEECCCCCEEECCCCCCCHHHH
KLAIQEHDPEATYGGFYTQEQMKEIIDYARSRQVTVVPEIDLPGHSYAAMHAYGDLICDG
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCC
VDFPVEGKKGRDAVCMGRPETLRFVKDVVDELKAVFPPGSPIHLGHDEVSAEAWKKCRYC
CCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHH
QNRLKNLREKDLKALGRDFLQQIADYVRKDGYDAIVWDEAGELEADKHILVMAWRGNGFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECCCCEE
AAAARKGHPVILAPCSHFYFDYYQSAASTEPKAVGGLIPLKQVYGYELPELSPEEAARVR
EECCCCCCCEEEECHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHCCCCCCCCHHHHHHHC
GLQANIWTEYLYNMGLVEYMAWPRALALSERAWSDCDPRDYKSFRSRASRALKILEKLAV
CCHHHHHHHHHHHCCHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KYRPMDEED
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]