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The map label for this gene is yhdT [H]

Identifier: 187734889

GI number: 187734889

Start: 456376

End: 457710

Strand: Reverse

Name: yhdT [H]

Synonym: Amuc_0381

Alternate gene names: 187734889

Gene position: 457710-456376 (Counterclockwise)

Preceding gene: 187734890

Following gene: 187734888

Centisome position: 17.18

GC content: 51.16

Gene sequence:

>1335_bases
ATGATTCTTTTTGTCACTTTCGTTATTCTTTTTCTGATTCTGGTCAACGCCTTTTATGTTGCAGCAGAATTCGCCGCAGT
GAGCGTACGCCGCAACATGATCCGGGAAATGGCGGAGAACGGCAGCAGGGTGGCTGTTCATCTGCTTAAGATTTTGGAAA
ATACAAAAGAGCTGGACCGCTACATTGCGGCTTGCCAGTTCGGCATTACCATTTCCAGCCTGGTTCTGGGCGCATACGGA
CAGGTTGAACTGGCCGCCTATCTGTTCCCTCTGTTTGAGCGGTTTGGTGGGATGGACTCCGTAATGGCCAATTCTGCAGC
CGCTCTTGTTGTACTGATAGGCTTGACGGTTTTTCAGGTAATTCTTGGAGAATTGATGCCCAAATCCCTGGCTCTTCAGT
TTCCCAAGCAGGCGGCCTTGTATACTTATTATCCCATGCGATGGACACTGGCTTTCTTCGCATGGTTCATTGACTTTCTT
AATGGAAGCGGTTTGTTGCTTCTTAAACTGTTCCGGCTCCCACCTGGCGGCCATCAGCACATCCACTCCCAGCAGGAGAT
TAATATGCTGCTGGATGAAAGCCACCAGGGCGGGATGTTGGAGGAAGATGAGCATGAACGGCTGCACAGCGCTTTGTCCC
TGGCGGAACGAACGGTGGAACAAATTATGATTCCCCGTTTTCAGCTTGTTTGCCTGGATGTGGATGCCACACAGGAAGAT
ATTTTGAATATGATCGCAGATAGGCCTCATACCCATATTCCCGTGTATGAAGGGAACCGTGAATCTGTCATTGGCATGCT
GCATATTAAAGATATGGTATCCGCTTATGCGGAAAAGGGAATTCTGCCTCCTCTCCGTTCCATGCTGAGGCAGGTGCCAT
GCGTGATGGAAATGCAGACGGTAGAGATGCTGATGGCCCGTTTGCGGGAAGACAGGGCCAAGGAAGCCTTTGTTCTGGAT
GAATACGGTAAGTTTGTGGGGCTGGTGACGCTGGAACGTCTGCTGGGAGAAATGGTGGGAGATATAGATGAGGAATTCAT
CCGTTCCGGGGAAAAGGTGGAAACCCTTCCGGATGGTTCCGTGCGCATCCCCGGCATGATGCGTGCCCATAAGGCGGAAT
GCCTGGTACCCTTTTTGATGAATGGCGCCACTACTGTGGGCGGCTGCGTGATCAAGCACATGTCCTGCATTCCGAAGGAT
GGGGACCGCCTGATTATTGCCGGACGCGTGCTTGTGGTGGAAAAGATGGACCATAACCGTGTTTCCTCTATCCTGCTGCT
GCCTCCGGAGAGAAAGGAAAATGAATTTGCCATGGAAAGCGGGGTGGATGCATGA

Upstream 100 bases:

>100_bases
TTTCCGCATGGCAGATTTTTTTGTTTCCCGTTCTTGACAGGATTTTTTCGGTTCCTATGATGCGGATGCCCGTTGCGTTT
TACGGACACCCCTGCCATAC

Downstream 100 bases:

>100_bases
TGACGGTTTTCATTATTCTGTTGCTGATTGTGCTGAACGGCCTGTTTGTGGCTGCAGAATTCGCGTTGCTTGGCGCTCCG
CGTGCGGCATTGGAGCAGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MILFVTFVILFLILVNAFYVAAEFAAVSVRRNMIREMAENGSRVAVHLLKILENTKELDRYIAACQFGITISSLVLGAYG
QVELAAYLFPLFERFGGMDSVMANSAAALVVLIGLTVFQVILGELMPKSLALQFPKQAALYTYYPMRWTLAFFAWFIDFL
NGSGLLLLKLFRLPPGGHQHIHSQQEINMLLDESHQGGMLEEDEHERLHSALSLAERTVEQIMIPRFQLVCLDVDATQED
ILNMIADRPHTHIPVYEGNRESVIGMLHIKDMVSAYAEKGILPPLRSMLRQVPCVMEMQTVEMLMARLREDRAKEAFVLD
EYGKFVGLVTLERLLGEMVGDIDEEFIRSGEKVETLPDGSVRIPGMMRAHKAECLVPFLMNGATTVGGCVIKHMSCIPKD
GDRLIIAGRVLVVEKMDHNRVSSILLLPPERKENEFAMESGVDA

Sequences:

>Translated_444_residues
MILFVTFVILFLILVNAFYVAAEFAAVSVRRNMIREMAENGSRVAVHLLKILENTKELDRYIAACQFGITISSLVLGAYG
QVELAAYLFPLFERFGGMDSVMANSAAALVVLIGLTVFQVILGELMPKSLALQFPKQAALYTYYPMRWTLAFFAWFIDFL
NGSGLLLLKLFRLPPGGHQHIHSQQEINMLLDESHQGGMLEEDEHERLHSALSLAERTVEQIMIPRFQLVCLDVDATQED
ILNMIADRPHTHIPVYEGNRESVIGMLHIKDMVSAYAEKGILPPLRSMLRQVPCVMEMQTVEMLMARLREDRAKEAFVLD
EYGKFVGLVTLERLLGEMVGDIDEEFIRSGEKVETLPDGSVRIPGMMRAHKAECLVPFLMNGATTVGGCVIKHMSCIPKD
GDRLIIAGRVLVVEKMDHNRVSSILLLPPERKENEFAMESGVDA
>Mature_444_residues
MILFVTFVILFLILVNAFYVAAEFAAVSVRRNMIREMAENGSRVAVHLLKILENTKELDRYIAACQFGITISSLVLGAYG
QVELAAYLFPLFERFGGMDSVMANSAAALVVLIGLTVFQVILGELMPKSLALQFPKQAALYTYYPMRWTLAFFAWFIDFL
NGSGLLLLKLFRLPPGGHQHIHSQQEINMLLDESHQGGMLEEDEHERLHSALSLAERTVEQIMIPRFQLVCLDVDATQED
ILNMIADRPHTHIPVYEGNRESVIGMLHIKDMVSAYAEKGILPPLRSMLRQVPCVMEMQTVEMLMARLREDRAKEAFVLD
EYGKFVGLVTLERLLGEMVGDIDEEFIRSGEKVETLPDGSVRIPGMMRAHKAECLVPFLMNGATTVGGCVIKHMSCIPKD
GDRLIIAGRVLVVEKMDHNRVSSILLLPPERKENEFAMESGVDA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=329, Percent_Identity=29.7872340425532, Blast_Score=175, Evalue=9e-44,
Organism=Escherichia coli, GI1790664, Length=431, Percent_Identity=24.5939675174014, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI145693175, Length=426, Percent_Identity=23.7089201877934, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87082033, Length=260, Percent_Identity=27.3076923076923, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786879, Length=270, Percent_Identity=25.9259259259259, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788119, Length=268, Percent_Identity=25.7462686567164, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49814; Mature: 49814

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILFVTFVILFLILVNAFYVAAEFAAVSVRRNMIREMAENGSRVAVHLLKILENTKELDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
YIAACQFGITISSLVLGAYGQVELAAYLFPLFERFGGMDSVMANSAAALVVLIGLTVFQV
HHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ILGELMPKSLALQFPKQAALYTYYPMRWTLAFFAWFIDFLNGSGLLLLKLFRLPPGGHQH
HHHHHCCHHHHHHCCCHHHHEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHH
IHSQQEINMLLDESHQGGMLEEDEHERLHSALSLAERTVEQIMIPRFQLVCLDVDATQED
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHH
ILNMIADRPHTHIPVYEGNRESVIGMLHIKDMVSAYAEKGILPPLRSMLRQVPCVMEMQT
HHHHHHCCCCCCCCEEECCHHHEEHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHH
VEMLMARLREDRAKEAFVLDEYGKFVGLVTLERLLGEMVGDIDEEFIRSGEKVETLPDGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEECCCCC
VRIPGMMRAHKAECLVPFLMNGATTVGGCVIKHMSCIPKDGDRLIIAGRVLVVEKMDHNR
EECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEECEEEEEEECCCCC
VSSILLLPPERKENEFAMESGVDA
CCEEEEECCCCCCCCHHHHCCCCC
>Mature Secondary Structure
MILFVTFVILFLILVNAFYVAAEFAAVSVRRNMIREMAENGSRVAVHLLKILENTKELDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
YIAACQFGITISSLVLGAYGQVELAAYLFPLFERFGGMDSVMANSAAALVVLIGLTVFQV
HHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ILGELMPKSLALQFPKQAALYTYYPMRWTLAFFAWFIDFLNGSGLLLLKLFRLPPGGHQH
HHHHHCCHHHHHHCCCHHHHEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHH
IHSQQEINMLLDESHQGGMLEEDEHERLHSALSLAERTVEQIMIPRFQLVCLDVDATQED
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHH
ILNMIADRPHTHIPVYEGNRESVIGMLHIKDMVSAYAEKGILPPLRSMLRQVPCVMEMQT
HHHHHHCCCCCCCCEEECCHHHEEHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHH
VEMLMARLREDRAKEAFVLDEYGKFVGLVTLERLLGEMVGDIDEEFIRSGEKVETLPDGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEECCCCC
VRIPGMMRAHKAECLVPFLMNGATTVGGCVIKHMSCIPKDGDRLIIAGRVLVVEKMDHNR
EECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEECEEEEEEECCCCC
VSSILLLPPERKENEFAMESGVDA
CCEEEEECCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]