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The map label for this gene is yhdP [H]

Identifier: 187734888

GI number: 187734888

Start: 455054

End: 456379

Strand: Reverse

Name: yhdP [H]

Synonym: Amuc_0380

Alternate gene names: 187734888

Gene position: 456379-455054 (Counterclockwise)

Preceding gene: 187734889

Following gene: 187734887

Centisome position: 17.13

GC content: 55.51

Gene sequence:

>1326_bases
ATGATGACGGTTTTCATTATTCTGTTGCTGATTGTGCTGAACGGCCTGTTTGTGGCTGCAGAATTCGCGTTGCTTGGCGC
TCCGCGTGCGGCATTGGAGCAGATGGGTGTGTCCGGCAACATGGTGGCGCGCCGCGTTTCCCAGATATTGAAAACGCCCC
GGTTACAGGACCGCTACATTGCTACGGCGCAGCTTGGCGTCACGTTCGCCAGTCTGGGGTTGGGTATGTACGGAGAGCAT
GCGGTAGCCGGATGGCTTCATGAATGGTTGGCGCAGTACGGCTGGGCTTCCTGGCTGGTGGCTCATGGCGCAGCCAGCAT
CCTGTCTGTGGCGGTGCTGACGTACCTGCATATTGTTCTTGGGGAAATGGTGCCCAAGGCGCTGTCCCTACAGTACGCCG
CAAAGCTTTGCCTCATCATTGCGATGCCCATGTACGTGATCCAGCTCTGCCTGTATCCTCTGGTAGTGGGTATGAATGCC
CTGGGCAATTTCTTTCTGGGGTTGCTGGGTGTGGACCGTAATGAATCCAAGTCCCACTACCATTCTGCGGAAGAACTCCA
GTATATTATTGAAGAGAGCCATGAGAACGGGGCGTTGCCGCAGGAATCCGGCCGCATCATGGACGGCTTGTTTGACCTGG
ATGATCTGTATGTACACCAGGTCATGACCCCGCGCGTCAGGATAGACGCCATTCCAGAAGGGGCGGAACATGAGCAGATA
CGGGAAATTGTGCGTCGCACTCGCCGTACGCGTTACCCTGTCTACCGCGGTGATCTGGACCATGTGGTGGGCATGGTGCA
TGCCCGCGATCTGTTCCGTATCATGTTCCGCAGAAAGGCTCTGACTCCTGAATACATTCATGCCATACCCAAGGTTCCCA
AAACGGTGAAGTTTGACAATGTGGTGGAAATCATGAGGAAGGACAATGTGCGCCTTGCCATTATTCTGGATGAGCACGGG
GGGACTTCCGGACTTTTGACCCTGACGGATGTTTTTTCCGAAGTAATGGGCTGGGACCGAGGCCGCATTAAAGTGCTAAC
GGAGTTGTCTAGGGATGCGGTGGGCTTCTCCTGTGACGTATCCGGTCTGGCACGCATTGAGGAATTGGGGGAGGCCATGG
ACATGGATTTGGAGGACGGGGAAATAGACACCGTAGGGGGCCTGATTCTTAATTTGCTGGAAGCTCCTGCGGAGGAAGGA
GATACTGTCGGCTATAGAGGGCTGGAATTCAAGGTGACCCGGACGGAGAATGGCGGTGTGGAGCGCTGTACCGTGACCCG
GATTACTCCCCTGATGCGGGAGGAGGTCCTGGAAGAGGAGGAATAA

Upstream 100 bases:

>100_bases
TTGTGGTGGAAAAGATGGACCATAACCGTGTTTCCTCTATCCTGCTGCTGCCTCCGGAGAGAAAGGAAAATGAATTTGCC
ATGGAAAGCGGGGTGGATGC

Downstream 100 bases:

>100_bases
TCTGCCGTTTACGGACTGGGCATGTCAAGGACTGTGCTGCCTGATGTAAAAGTTCCTTGGTGGAGCGCGTATGATATGGC
AGAATATTTCCGCCATGTCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MMTVFIILLLIVLNGLFVAAEFALLGAPRAALEQMGVSGNMVARRVSQILKTPRLQDRYIATAQLGVTFASLGLGMYGEH
AVAGWLHEWLAQYGWASWLVAHGAASILSVAVLTYLHIVLGEMVPKALSLQYAAKLCLIIAMPMYVIQLCLYPLVVGMNA
LGNFFLGLLGVDRNESKSHYHSAEELQYIIEESHENGALPQESGRIMDGLFDLDDLYVHQVMTPRVRIDAIPEGAEHEQI
REIVRRTRRTRYPVYRGDLDHVVGMVHARDLFRIMFRRKALTPEYIHAIPKVPKTVKFDNVVEIMRKDNVRLAIILDEHG
GTSGLLTLTDVFSEVMGWDRGRIKVLTELSRDAVGFSCDVSGLARIEELGEAMDMDLEDGEIDTVGGLILNLLEAPAEEG
DTVGYRGLEFKVTRTENGGVERCTVTRITPLMREEVLEEEE

Sequences:

>Translated_441_residues
MMTVFIILLLIVLNGLFVAAEFALLGAPRAALEQMGVSGNMVARRVSQILKTPRLQDRYIATAQLGVTFASLGLGMYGEH
AVAGWLHEWLAQYGWASWLVAHGAASILSVAVLTYLHIVLGEMVPKALSLQYAAKLCLIIAMPMYVIQLCLYPLVVGMNA
LGNFFLGLLGVDRNESKSHYHSAEELQYIIEESHENGALPQESGRIMDGLFDLDDLYVHQVMTPRVRIDAIPEGAEHEQI
REIVRRTRRTRYPVYRGDLDHVVGMVHARDLFRIMFRRKALTPEYIHAIPKVPKTVKFDNVVEIMRKDNVRLAIILDEHG
GTSGLLTLTDVFSEVMGWDRGRIKVLTELSRDAVGFSCDVSGLARIEELGEAMDMDLEDGEIDTVGGLILNLLEAPAEEG
DTVGYRGLEFKVTRTENGGVERCTVTRITPLMREEVLEEEE
>Mature_441_residues
MMTVFIILLLIVLNGLFVAAEFALLGAPRAALEQMGVSGNMVARRVSQILKTPRLQDRYIATAQLGVTFASLGLGMYGEH
AVAGWLHEWLAQYGWASWLVAHGAASILSVAVLTYLHIVLGEMVPKALSLQYAAKLCLIIAMPMYVIQLCLYPLVVGMNA
LGNFFLGLLGVDRNESKSHYHSAEELQYIIEESHENGALPQESGRIMDGLFDLDDLYVHQVMTPRVRIDAIPEGAEHEQI
REIVRRTRRTRYPVYRGDLDHVVGMVHARDLFRIMFRRKALTPEYIHAIPKVPKTVKFDNVVEIMRKDNVRLAIILDEHG
GTSGLLTLTDVFSEVMGWDRGRIKVLTELSRDAVGFSCDVSGLARIEELGEAMDMDLEDGEIDTVGGLILNLLEAPAEEG
DTVGYRGLEFKVTRTENGGVERCTVTRITPLMREEVLEEEE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=383, Percent_Identity=30.0261096605744, Blast_Score=197, Evalue=2e-50,
Organism=Escherichia coli, GI1790664, Length=434, Percent_Identity=23.0414746543779, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI145693175, Length=427, Percent_Identity=24.1217798594848, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786879, Length=267, Percent_Identity=26.9662921348315, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87082033, Length=264, Percent_Identity=26.1363636363636, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788119, Length=242, Percent_Identity=23.5537190082645, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49205; Mature: 49205

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTVFIILLLIVLNGLFVAAEFALLGAPRAALEQMGVSGNMVARRVSQILKTPRLQDRYI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHH
ATAQLGVTFASLGLGMYGEHAVAGWLHEWLAQYGWASWLVAHGAASILSVAVLTYLHIVL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
GEMVPKALSLQYAAKLCLIIAMPMYVIQLCLYPLVVGMNALGNFFLGLLGVDRNESKSHY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
HSAEELQYIIEESHENGALPQESGRIMDGLFDLDDLYVHQVMTPRVRIDAIPEGAEHEQI
CCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCHHHHHHHHHCCCCEEEECCCCCCCHHHH
REIVRRTRRTRYPVYRGDLDHVVGMVHARDLFRIMFRRKALTPEYIHAIPKVPKTVKFDN
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHH
VVEIMRKDNVRLAIILDEHGGTSGLLTLTDVFSEVMGWDRGRIKVLTELSRDAVGFSCDV
HHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCH
SGLARIEELGEAMDMDLEDGEIDTVGGLILNLLEAPAEEGDTVGYRGLEFKVTRTENGGV
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCC
ERCTVTRITPLMREEVLEEEE
CEEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMTVFIILLLIVLNGLFVAAEFALLGAPRAALEQMGVSGNMVARRVSQILKTPRLQDRYI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHH
ATAQLGVTFASLGLGMYGEHAVAGWLHEWLAQYGWASWLVAHGAASILSVAVLTYLHIVL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
GEMVPKALSLQYAAKLCLIIAMPMYVIQLCLYPLVVGMNALGNFFLGLLGVDRNESKSHY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
HSAEELQYIIEESHENGALPQESGRIMDGLFDLDDLYVHQVMTPRVRIDAIPEGAEHEQI
CCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCHHHHHHHHHCCCCEEEECCCCCCCHHHH
REIVRRTRRTRYPVYRGDLDHVVGMVHARDLFRIMFRRKALTPEYIHAIPKVPKTVKFDN
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHH
VVEIMRKDNVRLAIILDEHGGTSGLLTLTDVFSEVMGWDRGRIKVLTELSRDAVGFSCDV
HHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCH
SGLARIEELGEAMDMDLEDGEIDTVGGLILNLLEAPAEEGDTVGYRGLEFKVTRTENGGV
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCC
ERCTVTRITPLMREEVLEEEE
CEEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]