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The map label for this gene is dapB

Identifier: 187734769

GI number: 187734769

Start: 314097

End: 314837

Strand: Reverse

Name: dapB

Synonym: Amuc_0257

Alternate gene names: 187734769

Gene position: 314837-314097 (Counterclockwise)

Preceding gene: 187734770

Following gene: 187734768

Centisome position: 11.82

GC content: 54.12

Gene sequence:

>741_bases
ATGATTTCCATTCTTGTTACAGGCATTTCGGGCCGCATGGGCCAAGCTATTCAAGAGGCGGTGACGCAGAATCCGGATAC
TTGCGTGGGTTCTACTCATGATCAGGGACAGGAGCTTTATCCCGCCCTCGCCAAATGCGACGTAGCCATTGATTTTTCCC
ATCACGCTTTCACCAGCACTCTGCTGGCGGAAGCTGTTGCCAATAACAAACCTCTGGTGATTGGCACTACGGGGCATACG
GAGCTGGAACGCCAGGAGATCGTGGACGCTGCGGCATCCATTCCGATTGTGTTCGCTTCCAATTATTCCGTAGGGGTGAA
CGCCCTGTTCTGGCTGACGCGCAAGGCTGCACAGATTCTGGGAGGCAGCTGCGATATAGAGGTAATGGAGATGCATCACC
GTCACAAAATTGATGCTCCTTCCGGTACTGCCCGGACACTGGCGGAAATCCTGTCCGGCGCCATTGACAGGAATTATGAA
GATAGTGTGGTTTTTGGCCGTGAAGGGTTGGTAGGGCCTCGACCCGCCAAAGAAATAGGCATGCATTCCCTGCGGGGAGG
GGATGTGGTGGGGGACCATACTGTAATATTTGCTTCCGATGGTGAACGGCTGGAACTTACCCATAAGGCGTCCAGCCGTA
TGACATTTGCCTCCGGAGCAGTTCGTGCGGCTCTCTGGCTCCAAGGCAGGGAACCGGGTCTGTATACCATGGAAGACGTT
CTGGGGTTGTCCCAATTATAA

Upstream 100 bases:

>100_bases
GCCCGGCATACGTCTTCCGCTGGTTCCATTGGCGGAAGAGAAGGAAGCTCAGCTTTCCGCTCTTCTTCAGCGTTTCAATA
TTCTTTAACATTTTAGTGAT

Downstream 100 bases:

>100_bases
CTTTTTCGGCATCGTGGCCGTTCTTCTTTTCCGGAACGGCCACGATGTTTTTTGCTGATGAAGAGAGCAGGCATTGCACT
GGGGTCCAATCTTGGGGATA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MISILVTGISGRMGQAIQEAVTQNPDTCVGSTHDQGQELYPALAKCDVAIDFSHHAFTSTLLAEAVANNKPLVIGTTGHT
ELERQEIVDAAASIPIVFASNYSVGVNALFWLTRKAAQILGGSCDIEVMEMHHRHKIDAPSGTARTLAEILSGAIDRNYE
DSVVFGREGLVGPRPAKEIGMHSLRGGDVVGDHTVIFASDGERLELTHKASSRMTFASGAVRAALWLQGREPGLYTMEDV
LGLSQL

Sequences:

>Translated_246_residues
MISILVTGISGRMGQAIQEAVTQNPDTCVGSTHDQGQELYPALAKCDVAIDFSHHAFTSTLLAEAVANNKPLVIGTTGHT
ELERQEIVDAAASIPIVFASNYSVGVNALFWLTRKAAQILGGSCDIEVMEMHHRHKIDAPSGTARTLAEILSGAIDRNYE
DSVVFGREGLVGPRPAKEIGMHSLRGGDVVGDHTVIFASDGERLELTHKASSRMTFASGAVRAALWLQGREPGLYTMEDV
LGLSQL
>Mature_246_residues
MISILVTGISGRMGQAIQEAVTQNPDTCVGSTHDQGQELYPALAKCDVAIDFSHHAFTSTLLAEAVANNKPLVIGTTGHT
ELERQEIVDAAASIPIVFASNYSVGVNALFWLTRKAAQILGGSCDIEVMEMHHRHKIDAPSGTARTLAEILSGAIDRNYE
DSVVFGREGLVGPRPAKEIGMHSLRGGDVVGDHTVIFASDGERLELTHKASSRMTFASGAVRAALWLQGREPGLYTMEDV
LGLSQL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=200, Percent_Identity=54.5, Blast_Score=203, Evalue=7e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_AKKM8 (B2UMF1)

Other databases:

- EMBL:   CP001071
- RefSeq:   YP_001876881.1
- ProteinModelPortal:   B2UMF1
- SMR:   B2UMF1
- GeneID:   6275246
- GenomeReviews:   CP001071_GR
- KEGG:   amu:Amuc_0257
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 26306; Mature: 26306

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISILVTGISGRMGQAIQEAVTQNPDTCVGSTHDQGQELYPALAKCDVAIDFSHHAFTST
CEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCEEEEECCHHHHHHH
LLAEAVANNKPLVIGTTGHTELERQEIVDAAASIPIVFASNYSVGVNALFWLTRKAAQIL
HHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHH
GGSCDIEVMEMHHRHKIDAPSGTARTLAEILSGAIDRNYEDSVVFGREGLVGPRPAKEIG
CCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHHHC
MHSLRGGDVVGDHTVIFASDGERLELTHKASSRMTFASGAVRAALWLQGREPGLYTMEDV
CHHCCCCCEECCCEEEEECCCCEEEEEECCCCCEEEHHCHHEEEEEEECCCCCCEEHHHH
LGLSQL
HHHCCC
>Mature Secondary Structure
MISILVTGISGRMGQAIQEAVTQNPDTCVGSTHDQGQELYPALAKCDVAIDFSHHAFTST
CEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCEEEEECCHHHHHHH
LLAEAVANNKPLVIGTTGHTELERQEIVDAAASIPIVFASNYSVGVNALFWLTRKAAQIL
HHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHH
GGSCDIEVMEMHHRHKIDAPSGTARTLAEILSGAIDRNYEDSVVFGREGLVGPRPAKEIG
CCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHHHC
MHSLRGGDVVGDHTVIFASDGERLELTHKASSRMTFASGAVRAALWLQGREPGLYTMEDV
CHHCCCCCEECCCEEEEECCCCEEEEEECCCCCEEEHHCHHEEEEEEECCCCCCEEHHHH
LGLSQL
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA