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The map label for this gene is livK [C]

Identifier: 186477763

GI number: 186477763

Start: 3385721

End: 3386869

Strand: Reverse

Name: livK [C]

Synonym: Bphy_3017

Alternate gene names: 186477763

Gene position: 3386869-3385721 (Counterclockwise)

Preceding gene: 186477764

Following gene: 186477758

Centisome position: 97.35

GC content: 61.36

Gene sequence:

>1149_bases
ATGCAACACACGATGAAAAAGCTGGCAGGCGCGACGTTGTTCGCAGCCATGTCGCTGGCGGGGACCGCGCATGCACAGCA
GGTCGAAGACGTGAAGATCGGCTTCGCGGGTCCGATGACGGGCGCGCAAGCGCACTACGGCAAGGACTTCCAGAACGGCA
TCACGCTCGCAGTCGAAGACATGAACGCGACGAAGCCGATGATCGGCGGCAAGCAGGTTCGCTTCGTGCTGGACGTCGCC
GACGACCAGGCTGACCCGCGCACGGGTACGACCGTCGCGCAGAAGCTGGTCGACGACAACATCAAGGGCATGCTGGGTCA
CTTCAACTCCGGCACGACGATCCCGGCCTCGCGCATCTACGCGAACGCGGGCATTCCGCAGATCGCGATGGCGACGGCGC
CCGAATACACGCAGCAGGGCTTCAAGACGACGTTCCGCATGATGACCTCGGACACGCAGCAAGGCTCCGTTGCGGGCACG
TTCGCAGTGAAGAGCCTGGGCATGAAGAAGATCGCGATCGTCGACGACCGCACGGCATACGGCCAGGGTCTTGCCGACCA
GTTCGAGAAGGCAGCGAAGGCGGCGGGCGGCACGATCGTCGATCGTGAATTCACGAACGACAAGGCTGTCGACTTCAAGT
CGATCCTCACGAAGCTGAAGTCGGTTCAGCCGGATCTGATCTATTACGGCGGCGCCGATTCGCAGGCAGCGCCGATGGTC
AAGCAGATGAAGACGCTGGGCATCAAGGCACCGCTGATGGGCGGCGAAATGGTCCACACGCCGACGTTCCTGCAAGTCGC
TGGCGATGCCGCTAACGGCACGGTGGCTTCGCTGGCTGGTCTGCCGCTGGAAGAAATGCCGGGCGGCAAGGACTATGTCG
CGAAGTACAAGAAGCGCTTCGGTGAAGACGTTCAGACGTACTCGCCGTACGCTTACGACGGTGCGATGGCGATGTTCGAC
GCGATGAAGAAGGCGAACTCGACGGATCCGGCGAAGTACCTGCCGTTGCTCGCGAAGACGAGCATGCCTGCTGTGACGAC
CAAAGATCTCGCTTATGACGCCAAGGGCGATCTGAAAAACGGTGGCATCACGCTGTATAAGGTCGTTGATGGGAAGTGGA
CGACGCTGCAGAGCGTGGGTGGCAAGTAA

Upstream 100 bases:

>100_bases
GACGATCGGCTGAGCGAACCTCGCTCGATCGATTCAAAAAATGGCGCGAGACGGCGACCCCGATCACCGCGCCGTCCACA
CCTGGTACCAAGGAGAAGAT

Downstream 100 bases:

>100_bases
GTTTTTTTGCCTTGCGGCGCTTGGGGTTGTTGTTAGCTGAGCGCTGCTGATTTTGTGGAAGCCTCGTAGGGTTTTTGCTC
TGCGAGGCTTTTGTTTTTTG

Product: extracellular ligand-binding receptor

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MQHTMKKLAGATLFAAMSLAGTAHAQQVEDVKIGFAGPMTGAQAHYGKDFQNGITLAVEDMNATKPMIGGKQVRFVLDVA
DDQADPRTGTTVAQKLVDDNIKGMLGHFNSGTTIPASRIYANAGIPQIAMATAPEYTQQGFKTTFRMMTSDTQQGSVAGT
FAVKSLGMKKIAIVDDRTAYGQGLADQFEKAAKAAGGTIVDREFTNDKAVDFKSILTKLKSVQPDLIYYGGADSQAAPMV
KQMKTLGIKAPLMGGEMVHTPTFLQVAGDAANGTVASLAGLPLEEMPGGKDYVAKYKKRFGEDVQTYSPYAYDGAMAMFD
AMKKANSTDPAKYLPLLAKTSMPAVTTKDLAYDAKGDLKNGGITLYKVVDGKWTTLQSVGGK

Sequences:

>Translated_382_residues
MQHTMKKLAGATLFAAMSLAGTAHAQQVEDVKIGFAGPMTGAQAHYGKDFQNGITLAVEDMNATKPMIGGKQVRFVLDVA
DDQADPRTGTTVAQKLVDDNIKGMLGHFNSGTTIPASRIYANAGIPQIAMATAPEYTQQGFKTTFRMMTSDTQQGSVAGT
FAVKSLGMKKIAIVDDRTAYGQGLADQFEKAAKAAGGTIVDREFTNDKAVDFKSILTKLKSVQPDLIYYGGADSQAAPMV
KQMKTLGIKAPLMGGEMVHTPTFLQVAGDAANGTVASLAGLPLEEMPGGKDYVAKYKKRFGEDVQTYSPYAYDGAMAMFD
AMKKANSTDPAKYLPLLAKTSMPAVTTKDLAYDAKGDLKNGGITLYKVVDGKWTTLQSVGGK
>Mature_382_residues
MQHTMKKLAGATLFAAMSLAGTAHAQQVEDVKIGFAGPMTGAQAHYGKDFQNGITLAVEDMNATKPMIGGKQVRFVLDVA
DDQADPRTGTTVAQKLVDDNIKGMLGHFNSGTTIPASRIYANAGIPQIAMATAPEYTQQGFKTTFRMMTSDTQQGSVAGT
FAVKSLGMKKIAIVDDRTAYGQGLADQFEKAAKAAGGTIVDREFTNDKAVDFKSILTKLKSVQPDLIYYGGADSQAAPMV
KQMKTLGIKAPLMGGEMVHTPTFLQVAGDAANGTVASLAGLPLEEMPGGKDYVAKYKKRFGEDVQTYSPYAYDGAMAMFD
AMKKANSTDPAKYLPLLAKTSMPAVTTKDLAYDAKGDLKNGGITLYKVVDGKWTTLQSVGGK

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI1789867, Length=356, Percent_Identity=31.1797752808989, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI48994941, Length=355, Percent_Identity=31.830985915493, Blast_Score=152, Evalue=4e-38,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 40564; Mature: 40564

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHTMKKLAGATLFAAMSLAGTAHAQQVEDVKIGFAGPMTGAQAHYGKDFQNGITLAVED
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCEEEEEC
MNATKPMIGGKQVRFVLDVADDQADPRTGTTVAQKLVDDNIKGMLGHFNSGTTIPASRIY
CCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHE
ANAGIPQIAMATAPEYTQQGFKTTFRMMTSDTQQGSVAGTFAVKSLGMKKIAIVDDRTAY
ECCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHCCCEEEEEEECCCHH
GQGLADQFEKAAKAAGGTIVDREFTNDKAVDFKSILTKLKSVQPDLIYYGGADSQAAPMV
CCCHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHH
KQMKTLGIKAPLMGGEMVHTPTFLQVAGDAANGTVASLAGLPLEEMPGGKDYVAKYKKRF
HHHHHHCCCCCCCCCCEECCCEEEEEECCCCCCCHHHHCCCCHHHCCCCHHHHHHHHHHH
GEDVQTYSPYAYDGAMAMFDAMKKANSTDPAKYLPLLAKTSMPAVTTKDLAYDAKGDLKN
CCCHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEHHHHCCCCCCCCCC
GGITLYKVVDGKWTTLQSVGGK
CCEEEEEEECCCEEEHHCCCCC
>Mature Secondary Structure
MQHTMKKLAGATLFAAMSLAGTAHAQQVEDVKIGFAGPMTGAQAHYGKDFQNGITLAVED
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCEEEEEC
MNATKPMIGGKQVRFVLDVADDQADPRTGTTVAQKLVDDNIKGMLGHFNSGTTIPASRIY
CCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHE
ANAGIPQIAMATAPEYTQQGFKTTFRMMTSDTQQGSVAGTFAVKSLGMKKIAIVDDRTAY
ECCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHCCCEEEEEEECCCHH
GQGLADQFEKAAKAAGGTIVDREFTNDKAVDFKSILTKLKSVQPDLIYYGGADSQAAPMV
CCCHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHH
KQMKTLGIKAPLMGGEMVHTPTFLQVAGDAANGTVASLAGLPLEEMPGGKDYVAKYKKRF
HHHHHHCCCCCCCCCCEECCCEEEEEECCCCCCCHHHHCCCCHHHCCCCHHHHHHHHHHH
GEDVQTYSPYAYDGAMAMFDAMKKANSTDPAKYLPLLAKTSMPAVTTKDLAYDAKGDLKN
CCCHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEHHHHCCCCCCCCCC
GGITLYKVVDGKWTTLQSVGGK
CCEEEEEEECCCEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA