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The map label for this gene is lgrA [H]

Identifier: 186477758

GI number: 186477758

Start: 3379561

End: 3380181

Strand: Reverse

Name: lgrA [H]

Synonym: Bphy_3012

Alternate gene names: 186477758

Gene position: 3380181-3379561 (Counterclockwise)

Preceding gene: 186477763

Following gene: 186477757

Centisome position: 97.15

GC content: 65.06

Gene sequence:

>621_bases
ATGAAAGTACTGTTTTTGACGAGTGGCGAGCAGGCGCGGCCGCTGGCCGACTGGATCGGCCAACGCGACACGTTGACCGT
GCGCGAGACGCCCGTGAGCGCGCAGGAGCTCGTCGCGCTCGCCCCGGACCTGATTGTAAGTCACTCGTATCGCCACATTC
TGAAGCGCGACGTGCTCGCGGCGGCGCCCGGCCGATTCATCAACCTGCATATCTCGCTGTTGCCCTATAACCGCGGCGCC
GATCCGAACCTGTGGTCGTTTCTCGACGCAACGCCGAAGGGCGTGTCGATCCACCTGATCGACGAGGGCATCGATACGGG
CGCGTTGCTGCTGCAACGCGAAGTGTCGTTCGACGAAGCCAGCGAGACGCTTGCCAGCAGCTACGCGAAGCTGCAGCAGG
CGATCAATGATCTGTTCATCGACAACTGGTCGTCGCTGCGCGACGGGCATATCGCGCCGCGCGCGCAAAGCGGCGCGGGC
ACGTTTCATCGCGCGAGCGAATTCGCGGCGCTCAAGGATGCGCTGCTGGGCGCTGAAGGATGGCATGTGCCGATCCCCGT
TCTCCGGCAGCGCTACCGCACATCGCGCGCCGTTGCGGCGCACGGCGGCAGGCAGGCATAG

Upstream 100 bases:

>100_bases
TTTCGTCATTCAGGTTTCCCTCTGCGTCCATCAGGTTCGCGAGGACGATGACAGCGTCGTAACGGGCGACAGTGAAATCT
TCAGGGTTCGGCATAGGGAA

Downstream 100 bases:

>100_bases
CAGGTCAAAACAGGCAGCGGGAACGCACAGGGCGGCTTACGGGAAGTACGGCTCCATATCAAGGAAGCGAACAATGTTGG
ACAACAAGTCAATTTTGATT

Product: formyl transferase domain-containing protein

Products: NA

Alternate protein names: ATP-dependent valine/leucine adenylase; Val/LeuA; Valine/leucine activase; ATP-dependent glycine adenylase; GlyA; Glycine activase [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKVLFLTSGEQARPLADWIGQRDTLTVRETPVSAQELVALAPDLIVSHSYRHILKRDVLAAAPGRFINLHISLLPYNRGA
DPNLWSFLDATPKGVSIHLIDEGIDTGALLLQREVSFDEASETLASSYAKLQQAINDLFIDNWSSLRDGHIAPRAQSGAG
TFHRASEFAALKDALLGAEGWHVPIPVLRQRYRTSRAVAAHGGRQA

Sequences:

>Translated_206_residues
MKVLFLTSGEQARPLADWIGQRDTLTVRETPVSAQELVALAPDLIVSHSYRHILKRDVLAAAPGRFINLHISLLPYNRGA
DPNLWSFLDATPKGVSIHLIDEGIDTGALLLQREVSFDEASETLASSYAKLQQAINDLFIDNWSSLRDGHIAPRAQSGAG
TFHRASEFAALKDALLGAEGWHVPIPVLRQRYRTSRAVAAHGGRQA
>Mature_206_residues
MKVLFLTSGEQARPLADWIGQRDTLTVRETPVSAQELVALAPDLIVSHSYRHILKRDVLAAAPGRFINLHISLLPYNRGA
DPNLWSFLDATPKGVSIHLIDEGIDTGALLLQREVSFDEASETLASSYAKLQQAINDLFIDNWSSLRDGHIAPRAQSGAG
TFHRASEFAALKDALLGAEGWHVPIPVLRQRYRTSRAVAAHGGRQA

Specific function: Activates valine (or leucine, but much less frequently), and then glycine and catalyzes the formation of the peptide bond in the first step of peptide synthesis. This enzyme may also play a role in N-formylation of the first amino acid residue in the synt

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

Organism=Escherichia coli, GI1788589, Length=168, Percent_Identity=31.547619047619, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR002376
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00551 Formyl_trans_N; PF00550 PP-binding [H]

EC number: NA

Molecular weight: Translated: 22579; Mature: 22579

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLFLTSGEQARPLADWIGQRDTLTVRETPVSAQELVALAPDLIVSHSYRHILKRDVLA
CEEEEEECCCCCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAPGRFINLHISLLPYNRGADPNLWSFLDATPKGVSIHLIDEGIDTGALLLQREVSFDEA
HCCCCEEEEEEEEEECCCCCCCCHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHCCHHHH
SETLASSYAKLQQAINDLFIDNWSSLRDGHIAPRAQSGAGTFHRASEFAALKDALLGAEG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
WHVPIPVLRQRYRTSRAVAAHGGRQA
CCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKVLFLTSGEQARPLADWIGQRDTLTVRETPVSAQELVALAPDLIVSHSYRHILKRDVLA
CEEEEEECCCCCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAPGRFINLHISLLPYNRGADPNLWSFLDATPKGVSIHLIDEGIDTGALLLQREVSFDEA
HCCCCEEEEEEEEEECCCCCCCCHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHCCHHHH
SETLASSYAKLQQAINDLFIDNWSSLRDGHIAPRAQSGAGTFHRASEFAALKDALLGAEG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
WHVPIPVLRQRYRTSRAVAAHGGRQA
CCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA