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The map label for this gene is putA [H]

Identifier: 186477764

GI number: 186477764

Start: 3386957

End: 3390919

Strand: Reverse

Name: putA [H]

Synonym: Bphy_3018

Alternate gene names: 186477764

Gene position: 3390919-3386957 (Counterclockwise)

Preceding gene: 186477766

Following gene: 186477763

Centisome position: 97.46

GC content: 65.56

Gene sequence:

>3963_bases
ATGGCGAGCACCACCCTTGGCGTAAAAGTCGACGACCTGCTGCGTACCCGGCTGAAAGATGCCGCGACGCGCCTCGAGCG
CACTCCCCACTGGCTGATCAAGCAGGCGATCTTCGCTTACCTCGAGAAGATCGAGCACGGCCAGCTTCCCGCCGAGCTGT
CCGGGCATCACGGCGCAACCGAACTGGCCGATGGTGCCGCCGATCCGGACGAAAGCGACGGACTGCATCCGTTCCTCGAA
TTCGCGCAGAGCGTGCAGCCGCAGTCGGTGCTGCGTGCGGCGATCACGGCTGCGTATCGACGGCCGGAGCCGGAATGCGT
GCCGTTCCTGATAGGCCAGGCGCGTCTGCCTGCGAATATCGCGAACGACGTGCAGGCCATGGCGAGCAAGCTCGTCGAAG
CACTGCGCTCGAAGAGCACGGGCGGCGGCGTCGAAGGGCTGATCCACGAGTTCTCGCTGTCGAGCCAGGAAGGTGTGGCG
CTGATGTGTCTCGCGGAAGCGCTGCTGCGCATTCCCGACCGCGCAACGCGCGACGCGCTGATTCGCGACAAGATCAGCAA
GGGCGACTGGCGTTCGCACGTCGGTCATGCACCGTCGCTGTTCGTGAACGCGGCGACGTGGGGCCTGATGATCACCGGCA
AGCTGGTGACGACGAATAGCGAAACGGGCCTGTCGTCGGCGCTCACGCGCATGATCGGCAAGGGCGGCGAGCCGCTGATC
CGCAAGGGCGTCGACATGGCGATGCGCCTGATGGGCGAGCAGTTCGTGACGGGTGAAACCATCTCCGAAGCGCTCGCCAA
CAGCCGCAAGTTCGAGGCACGCGGCTTCCGCTACTCCTACGACATGCTCGGCGAAGCCGCGACCACGGAAGCCGACGCGC
AGCGCTACTACGCATCGTACGAGCAGGCGATCCACGCGATCGGCAAGGCGGCGGGCGGCCGCGGCATCTACGAAGGCCCG
GGCATTTCGATCAAGCTGTCGGCGCTGCATCCGCGTTACTCGCGTTCGCAGCAGGAACGCACGATGAGCGAGCTGCTGCC
GCGCGTGCGCGCGCTTGCGATTCTCGCGCGCCGCTACGACATCGGCCTGAACATCGACGCTGAAGAAGCGGACCGTCTGG
AGATCTCGCTCGATCTGCTCGAAGCGCTGTGCTTCGACCCGGAGCTGCAAGGCTGGAATGGCATCGGCTTCGTCGTGCAG
GCATATCAGAAGCGCTGTCCGTTCGTGATCGACTACATCGTCGACCTCGCGCGTCGCAGCCGCCACCGCATCATGGTCCG
TCTGGTGAAGGGCGCGTACTGGGATACGGAAATCAAGCGCGCGCAGGTGGATGGCCTCGAAGGTTATCCCGTGTACACGC
GCAAGATCTATACGGACGTGTCGTACCTCGCGTGCGCGAAGAAGCTGCTCGGCGCACCGGATGCCGTCTATCCGCAGTTC
GCGACGCACAATGCGCACACGCTGTCCGCGATCTATCACCTGGCGGGCCAGAACTACTACCCCGGCCAGTACGAGTTCCA
GTGCCTGCACGGCATGGGTGAGCCGCTGTACGAAGAAGTGACGGGCCGCGACAAGCTGAATCGTCCGTGCCGCGTATATG
CGCCCGTCGGCACCCATGAAACGTTGCTCGCGTACCTTGTGCGCCGCCTGCTGGAAAACGGTGCGAACACATCATTCGTG
AACCGCATCGCTGATGAAACCGTGCCCGTGCAGGATCTCGTCGCCGATCCCGTCGATGAAGCTGCGAAGATCGTGCCGCT
CGGCGCGCCGCACGCGAAGATTCCGCTGCCGCGCAATCTGTACGGCGCGGAGCGCACCAATTCGATGGGCCTCGATCTGT
CGAACGAGCATCGCCTCGCGTCGCTGTCGTCGGCGCTGCTGGCTAGCGCGAATCATCCGTGGCGTGCCGCGCCGATGCTC
GAAGGCAACGAGATCGCCGTCGGTCGTGCACGGGACGTGCGTAACCCGTCGGATCACCGCGACCTCGTCGGCACGGTCGT
CGAAGCGACGCCGGAACACGTGAGCGCCGCGCTCGCGCATGCCGTCGCCGCTGCGCCCATCTGGCAGGCGACGCCTGTTG
AAGCGCGTGCCGATTGCCTCGCGCGAGCCGCCGATCTGCTCGAAGCGCAGATGCATACCCTGATGGGCCTCGTGGTGCGC
GAAGCGGGCAAGTCGCTGCCGAACGCCGTCGCCGAAATTCGCGAAGCGATCGACTTCCTGCGCTACTACTCGAGTCAGAT
CCGCGACGAGTTCTCGAACGACACGCATCGCCCCCTCGGTCCCGTCGTGTGTATCAGTCCGTGGAACTTCCCGCTGGCGA
TCTTCATGGGTCAGGTAGCCGCGGCGCTCGCCGCAGGCAACACGGTTTTGGCCAAGCCCGCCGAACAGACGCCGCTGATC
GCCGCGCAAGCCGTGCGCATTCTGCGCGAAGCGGGTGTGCCCGCGGGCGCAGTGCAACTGCTGCCGGGCGATGGCGAAAC
GGTTGGCGCTGCGCTGGTCGCCGATGCACGCACGCGCGCCGTGATGTTCACCGGCTCGACGGAAGTCGCGCGTCTCATCA
ACAAGACGCTTTCGAATCGCCTCGACCCTGATGGCAAGCCGATTCCGCTGATCGCCGAAACGGGCGGCCAGAACGCGATG
ATCGTCGATTCGTCGGCGCTCGCCGAACAGGTTGTGGCCGACGTGCTGCAATCGTCGTTCGATTCGGCCGGTCAACGTTG
TTCCGCGCTGCGCGTTCTCTGTCTTCAGGACGATGTCGCGGACCGCACGCTCGAAATGCTGACGGGCGCGATGAAGGAAC
TGGCGGTGGGCAATCCCGACCGTCTGTCGATCGACGTGGGTCCCGTGATCGACGCGGAAGCGAAGCGCGGTATCGACGCG
CATATCGCCTCGATGCGCGAGAAGGGCCGCAAGGTCACACAGATGCCGATGCCGGATGGCTGTGCAGCCGGTACGTTCGT
GCCGCCGACGCTGATCGAACTCGACAACATCGACGAACTGAAGCGTGAAGTGTTCGGCCCCGTGCTGCACGTGGTGCGTT
ACCGCCGCAGCGCGCTGGACAAACTGCTCGAACAGATCCGCGCGACGGGGTACGGGCTGACGCTCGGCATTCATACGCGC
ATCGACGAAACGATCGCGCATGTGATCGGCCGCGCGCACGTGGGCAATATCTACGTGAACCGCAACGTGATCGGCGCGGT
GGTCGGCGTGCAGCCGTTCGGCGGGGAAGGGCTGTCGGGCACGGGTCCGAAGGCGGGCGGCGCGCTGTATCTGCAGCGTC
TGCTGGCGACGCGTCCGGCCGGTTTGCCGAAGTCGCTTGCGCGGACCTTGATGGTCGACGCGTCGCAAGGCGCGGCGAAT
GGTGGGCAAAGCGCTGCACAAAACGGCAACGCGGCAAGCGATAATCCTGCCGCTGCGCTGACGACGCTGCGCGACTGGTT
GATCGCGGAACGCGAGCCGGTGCTGGCCGCACGTTGTGACGGCTACCTGTCGCACATCCCGGCGGGCGCGACGGCTGTGC
TGGCGGGCCCGACGGGCGAGCGCAACACGTACACGCTCGGCGCACGCGGCACGGTGCTGTGTGTTGCATCGACAGCGAGC
GGCGCGCGCGTGCAGTTCGCGGCGGCGCTGGCGACGGGCAACAAGGCGCTGTTCGAAGGCGCGGCGGGCGAGCAACTGTA
TGCCGCGCTGCCGCCGTCGCTGAAGCAGTACGCGAGCGTGAAGAAGAACGCCGAAGCATCGTTCGATGCCGCGCTCTTCG
AAGGCGACAGCGACGAGTTGCTGGCACTCGTGAAGGACATCGCGAAGCGCGCGGGTCCCATCGTGTCGGTGCAGGGCGTC
GCGGCACGCGCGCTGGAAAGCGGCGATGAGGATTACGCACTCGAACGCCTGTTGACGGAGCGTTCGGTGAGCGTGAATAC
GGCAGCAGCAGGCGGTAATGCAAATTTGATGACGATCGGCTGA

Upstream 100 bases:

>100_bases
CGTCTCGCCGAACTGGTTGCACCTTTTTATTGGGAGGGGTACGATTCGCCCAACTTTTTAGTCTTTGGCCGGCGTCCGCC
CGGCGCATAAAGAAGGAATC

Downstream 100 bases:

>100_bases
GCGAACCTCGCTCGATCGATTCAAAAAATGGCGCGAGACGGCGACCCCGATCACCGCGCCGTCCACACCTGGTACCAAGG
AGAAGATATGCAACACACGA

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1320; Mature: 1319

Protein sequence:

>1320_residues
MASTTLGVKVDDLLRTRLKDAATRLERTPHWLIKQAIFAYLEKIEHGQLPAELSGHHGATELADGAADPDESDGLHPFLE
FAQSVQPQSVLRAAITAAYRRPEPECVPFLIGQARLPANIANDVQAMASKLVEALRSKSTGGGVEGLIHEFSLSSQEGVA
LMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSETGLSSALTRMIGKGGEPLI
RKGVDMAMRLMGEQFVTGETISEALANSRKFEARGFRYSYDMLGEAATTEADAQRYYASYEQAIHAIGKAAGGRGIYEGP
GISIKLSALHPRYSRSQQERTMSELLPRVRALAILARRYDIGLNIDAEEADRLEISLDLLEALCFDPELQGWNGIGFVVQ
AYQKRCPFVIDYIVDLARRSRHRIMVRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLGAPDAVYPQF
ATHNAHTLSAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSFV
NRIADETVPVQDLVADPVDEAAKIVPLGAPHAKIPLPRNLYGAERTNSMGLDLSNEHRLASLSSALLASANHPWRAAPML
EGNEIAVGRARDVRNPSDHRDLVGTVVEATPEHVSAALAHAVAAAPIWQATPVEARADCLARAADLLEAQMHTLMGLVVR
EAGKSLPNAVAEIREAIDFLRYYSSQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPLI
AAQAVRILREAGVPAGAVQLLPGDGETVGAALVADARTRAVMFTGSTEVARLINKTLSNRLDPDGKPIPLIAETGGQNAM
IVDSSALAEQVVADVLQSSFDSAGQRCSALRVLCLQDDVADRTLEMLTGAMKELAVGNPDRLSIDVGPVIDAEAKRGIDA
HIASMREKGRKVTQMPMPDGCAAGTFVPPTLIELDNIDELKREVFGPVLHVVRYRRSALDKLLEQIRATGYGLTLGIHTR
IDETIAHVIGRAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPAGLPKSLARTLMVDASQGAAN
GGQSAAQNGNAASDNPAAALTTLRDWLIAEREPVLAARCDGYLSHIPAGATAVLAGPTGERNTYTLGARGTVLCVASTAS
GARVQFAAALATGNKALFEGAAGEQLYAALPPSLKQYASVKKNAEASFDAALFEGDSDELLALVKDIAKRAGPIVSVQGV
AARALESGDEDYALERLLTERSVSVNTAAAGGNANLMTIG

Sequences:

>Translated_1320_residues
MASTTLGVKVDDLLRTRLKDAATRLERTPHWLIKQAIFAYLEKIEHGQLPAELSGHHGATELADGAADPDESDGLHPFLE
FAQSVQPQSVLRAAITAAYRRPEPECVPFLIGQARLPANIANDVQAMASKLVEALRSKSTGGGVEGLIHEFSLSSQEGVA
LMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSETGLSSALTRMIGKGGEPLI
RKGVDMAMRLMGEQFVTGETISEALANSRKFEARGFRYSYDMLGEAATTEADAQRYYASYEQAIHAIGKAAGGRGIYEGP
GISIKLSALHPRYSRSQQERTMSELLPRVRALAILARRYDIGLNIDAEEADRLEISLDLLEALCFDPELQGWNGIGFVVQ
AYQKRCPFVIDYIVDLARRSRHRIMVRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLGAPDAVYPQF
ATHNAHTLSAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSFV
NRIADETVPVQDLVADPVDEAAKIVPLGAPHAKIPLPRNLYGAERTNSMGLDLSNEHRLASLSSALLASANHPWRAAPML
EGNEIAVGRARDVRNPSDHRDLVGTVVEATPEHVSAALAHAVAAAPIWQATPVEARADCLARAADLLEAQMHTLMGLVVR
EAGKSLPNAVAEIREAIDFLRYYSSQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPLI
AAQAVRILREAGVPAGAVQLLPGDGETVGAALVADARTRAVMFTGSTEVARLINKTLSNRLDPDGKPIPLIAETGGQNAM
IVDSSALAEQVVADVLQSSFDSAGQRCSALRVLCLQDDVADRTLEMLTGAMKELAVGNPDRLSIDVGPVIDAEAKRGIDA
HIASMREKGRKVTQMPMPDGCAAGTFVPPTLIELDNIDELKREVFGPVLHVVRYRRSALDKLLEQIRATGYGLTLGIHTR
IDETIAHVIGRAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPAGLPKSLARTLMVDASQGAAN
GGQSAAQNGNAASDNPAAALTTLRDWLIAEREPVLAARCDGYLSHIPAGATAVLAGPTGERNTYTLGARGTVLCVASTAS
GARVQFAAALATGNKALFEGAAGEQLYAALPPSLKQYASVKKNAEASFDAALFEGDSDELLALVKDIAKRAGPIVSVQGV
AARALESGDEDYALERLLTERSVSVNTAAAGGNANLMTIG
>Mature_1319_residues
ASTTLGVKVDDLLRTRLKDAATRLERTPHWLIKQAIFAYLEKIEHGQLPAELSGHHGATELADGAADPDESDGLHPFLEF
AQSVQPQSVLRAAITAAYRRPEPECVPFLIGQARLPANIANDVQAMASKLVEALRSKSTGGGVEGLIHEFSLSSQEGVAL
MCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSETGLSSALTRMIGKGGEPLIR
KGVDMAMRLMGEQFVTGETISEALANSRKFEARGFRYSYDMLGEAATTEADAQRYYASYEQAIHAIGKAAGGRGIYEGPG
ISIKLSALHPRYSRSQQERTMSELLPRVRALAILARRYDIGLNIDAEEADRLEISLDLLEALCFDPELQGWNGIGFVVQA
YQKRCPFVIDYIVDLARRSRHRIMVRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLGAPDAVYPQFA
THNAHTLSAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSFVN
RIADETVPVQDLVADPVDEAAKIVPLGAPHAKIPLPRNLYGAERTNSMGLDLSNEHRLASLSSALLASANHPWRAAPMLE
GNEIAVGRARDVRNPSDHRDLVGTVVEATPEHVSAALAHAVAAAPIWQATPVEARADCLARAADLLEAQMHTLMGLVVRE
AGKSLPNAVAEIREAIDFLRYYSSQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPLIA
AQAVRILREAGVPAGAVQLLPGDGETVGAALVADARTRAVMFTGSTEVARLINKTLSNRLDPDGKPIPLIAETGGQNAMI
VDSSALAEQVVADVLQSSFDSAGQRCSALRVLCLQDDVADRTLEMLTGAMKELAVGNPDRLSIDVGPVIDAEAKRGIDAH
IASMREKGRKVTQMPMPDGCAAGTFVPPTLIELDNIDELKREVFGPVLHVVRYRRSALDKLLEQIRATGYGLTLGIHTRI
DETIAHVIGRAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPAGLPKSLARTLMVDASQGAANG
GQSAAQNGNAASDNPAAALTTLRDWLIAEREPVLAARCDGYLSHIPAGATAVLAGPTGERNTYTLGARGTVLCVASTASG
ARVQFAAALATGNKALFEGAAGEQLYAALPPSLKQYASVKKNAEASFDAALFEGDSDELLALVKDIAKRAGPIVSVQGVA
ARALESGDEDYALERLLTERSVSVNTAAAGGNANLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=464, Percent_Identity=31.6810344827586, Blast_Score=189, Evalue=2e-47,
Organism=Homo sapiens, GI153266822, Length=466, Percent_Identity=30.2575107296137, Blast_Score=181, Evalue=4e-45,
Organism=Homo sapiens, GI25777732, Length=452, Percent_Identity=30.5309734513274, Blast_Score=175, Evalue=3e-43,
Organism=Homo sapiens, GI25777736, Length=484, Percent_Identity=30.3719008264463, Blast_Score=174, Evalue=5e-43,
Organism=Homo sapiens, GI25777734, Length=484, Percent_Identity=30.3719008264463, Blast_Score=174, Evalue=5e-43,
Organism=Homo sapiens, GI238859541, Length=485, Percent_Identity=30.3092783505155, Blast_Score=174, Evalue=5e-43,
Organism=Homo sapiens, GI25777730, Length=449, Percent_Identity=30.9576837416481, Blast_Score=171, Evalue=4e-42,
Organism=Homo sapiens, GI25777724, Length=462, Percent_Identity=29.004329004329, Blast_Score=171, Evalue=5e-42,
Organism=Homo sapiens, GI25777728, Length=405, Percent_Identity=30.1234567901235, Blast_Score=164, Evalue=7e-40,
Organism=Homo sapiens, GI21614513, Length=433, Percent_Identity=30.0230946882217, Blast_Score=157, Evalue=8e-38,
Organism=Homo sapiens, GI12007648, Length=466, Percent_Identity=27.0386266094421, Blast_Score=153, Evalue=1e-36,
Organism=Homo sapiens, GI4507229, Length=496, Percent_Identity=28.4274193548387, Blast_Score=145, Evalue=3e-34,
Organism=Homo sapiens, GI238814322, Length=448, Percent_Identity=27.4553571428571, Blast_Score=141, Evalue=4e-33,
Organism=Homo sapiens, GI11095441, Length=429, Percent_Identity=28.6713286713287, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI25777721, Length=509, Percent_Identity=27.7013752455796, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI115387104, Length=443, Percent_Identity=26.1851015801354, Blast_Score=136, Evalue=2e-31,
Organism=Homo sapiens, GI188035924, Length=461, Percent_Identity=26.6811279826464, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI310128093, Length=438, Percent_Identity=27.8538812785388, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI310128103, Length=461, Percent_Identity=26.6811279826464, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI25777726, Length=462, Percent_Identity=25.5411255411255, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI25952152, Length=460, Percent_Identity=26.5217391304348, Blast_Score=121, Evalue=4e-27,
Organism=Homo sapiens, GI310128091, Length=404, Percent_Identity=27.4752475247525, Blast_Score=117, Evalue=6e-26,
Organism=Homo sapiens, GI206597441, Length=444, Percent_Identity=25, Blast_Score=102, Evalue=3e-21,
Organism=Homo sapiens, GI206597439, Length=444, Percent_Identity=25, Blast_Score=102, Evalue=3e-21,
Organism=Homo sapiens, GI22907049, Length=444, Percent_Identity=25, Blast_Score=102, Evalue=3e-21,
Organism=Homo sapiens, GI310128087, Length=273, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=8e-20,
Organism=Homo sapiens, GI71773324, Length=391, Percent_Identity=24.5524296675192, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI4502043, Length=337, Percent_Identity=24.9258160237389, Blast_Score=94, Evalue=8e-19,
Organism=Homo sapiens, GI238814371, Length=337, Percent_Identity=24.9258160237389, Blast_Score=94, Evalue=8e-19,
Organism=Homo sapiens, GI310128089, Length=341, Percent_Identity=25.8064516129032, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI310128095, Length=327, Percent_Identity=25.9938837920489, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI73695881, Length=361, Percent_Identity=22.9916897506925, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI73695879, Length=361, Percent_Identity=22.9916897506925, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI301500698, Length=454, Percent_Identity=22.9074889867841, Blast_Score=81, Evalue=8e-15,
Organism=Homo sapiens, GI4557303, Length=356, Percent_Identity=23.876404494382, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI310128101, Length=220, Percent_Identity=27.7272727272727, Blast_Score=79, Evalue=4e-14,
Organism=Homo sapiens, GI73466520, Length=356, Percent_Identity=23.876404494382, Blast_Score=79, Evalue=4e-14,
Organism=Homo sapiens, GI310128099, Length=219, Percent_Identity=27.8538812785388, Blast_Score=78, Evalue=5e-14,
Organism=Homo sapiens, GI310128097, Length=274, Percent_Identity=25.9124087591241, Blast_Score=77, Evalue=2e-13,
Organism=Escherichia coli, GI1787250, Length=1348, Percent_Identity=65.9495548961424, Blast_Score=1727, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=461, Percent_Identity=31.236442516269, Blast_Score=184, Evalue=3e-47,
Organism=Escherichia coli, GI1788042, Length=450, Percent_Identity=30.4444444444444, Blast_Score=157, Evalue=5e-39,
Organism=Escherichia coli, GI1787684, Length=461, Percent_Identity=29.5010845986985, Blast_Score=156, Evalue=8e-39,
Organism=Escherichia coli, GI1787715, Length=452, Percent_Identity=30.5309734513274, Blast_Score=151, Evalue=3e-37,
Organism=Escherichia coli, GI1786504, Length=463, Percent_Identity=28.2937365010799, Blast_Score=145, Evalue=2e-35,
Organism=Escherichia coli, GI1787558, Length=416, Percent_Identity=31.0096153846154, Blast_Score=143, Evalue=9e-35,
Organism=Escherichia coli, GI87082295, Length=454, Percent_Identity=28.4140969162996, Blast_Score=140, Evalue=6e-34,
Organism=Escherichia coli, GI87081896, Length=413, Percent_Identity=29.2978208232446, Blast_Score=139, Evalue=2e-33,
Organism=Escherichia coli, GI87081926, Length=428, Percent_Identity=24.7663551401869, Blast_Score=116, Evalue=1e-26,
Organism=Escherichia coli, GI1787653, Length=439, Percent_Identity=24.373576309795, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17534447, Length=461, Percent_Identity=32.1041214750542, Blast_Score=192, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI25144435, Length=463, Percent_Identity=31.317494600432, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI32564736, Length=412, Percent_Identity=32.5242718446602, Blast_Score=165, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17562198, Length=493, Percent_Identity=29.4117647058824, Blast_Score=165, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI115532534, Length=375, Percent_Identity=32.5333333333333, Blast_Score=162, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI115534176, Length=483, Percent_Identity=28.5714285714286, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI32564151, Length=414, Percent_Identity=29.951690821256, Blast_Score=152, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI25143874, Length=501, Percent_Identity=26.3473053892216, Blast_Score=151, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI25143876, Length=502, Percent_Identity=26.4940239043825, Blast_Score=150, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI133930964, Length=442, Percent_Identity=27.3755656108597, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17551164, Length=495, Percent_Identity=25.4545454545455, Blast_Score=139, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI71986308, Length=427, Percent_Identity=28.3372365339578, Blast_Score=138, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17534119, Length=463, Percent_Identity=26.133909287257, Blast_Score=123, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI71995606, Length=445, Percent_Identity=26.0674157303371, Blast_Score=119, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71990744, Length=302, Percent_Identity=30.1324503311258, Blast_Score=118, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71995613, Length=402, Percent_Identity=25.6218905472637, Blast_Score=114, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI25146391, Length=415, Percent_Identity=23.855421686747, Blast_Score=95, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32566756, Length=415, Percent_Identity=23.855421686747, Blast_Score=94, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25146394, Length=415, Percent_Identity=23.855421686747, Blast_Score=94, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17564084, Length=329, Percent_Identity=25.2279635258359, Blast_Score=88, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320917, Length=460, Percent_Identity=31.7391304347826, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6321826, Length=482, Percent_Identity=30.0829875518672, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6325196, Length=460, Percent_Identity=31.0869565217391, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6323821, Length=472, Percent_Identity=31.3559322033898, Blast_Score=170, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6323822, Length=478, Percent_Identity=29.9163179916318, Blast_Score=164, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324950, Length=450, Percent_Identity=27.1111111111111, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319478, Length=454, Percent_Identity=26.431718061674, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6321828, Length=475, Percent_Identity=22.9473684210526, Blast_Score=95, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6323757, Length=329, Percent_Identity=25.2279635258359, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI20129399, Length=458, Percent_Identity=30.5676855895196, Blast_Score=179, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24668425, Length=525, Percent_Identity=27.8095238095238, Blast_Score=172, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24668417, Length=525, Percent_Identity=27.8095238095238, Blast_Score=172, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24668413, Length=525, Percent_Identity=27.8095238095238, Blast_Score=172, Evalue=1e-42,
Organism=Drosophila melanogaster, GI281362580, Length=454, Percent_Identity=26.8722466960352, Blast_Score=162, Evalue=2e-39,
Organism=Drosophila melanogaster, GI62472918, Length=454, Percent_Identity=26.8722466960352, Blast_Score=162, Evalue=2e-39,
Organism=Drosophila melanogaster, GI62472926, Length=454, Percent_Identity=26.8722466960352, Blast_Score=162, Evalue=2e-39,
Organism=Drosophila melanogaster, GI62472936, Length=454, Percent_Identity=26.8722466960352, Blast_Score=162, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21356737, Length=454, Percent_Identity=26.8722466960352, Blast_Score=162, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24650465, Length=455, Percent_Identity=27.6923076923077, Blast_Score=157, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24666674, Length=455, Percent_Identity=29.2307692307692, Blast_Score=148, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28574525, Length=454, Percent_Identity=27.9735682819383, Blast_Score=148, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24585660, Length=466, Percent_Identity=26.3948497854077, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28571806, Length=497, Percent_Identity=25.3521126760563, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28571802, Length=497, Percent_Identity=25.3521126760563, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28571800, Length=497, Percent_Identity=25.3521126760563, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28571798, Length=497, Percent_Identity=25.3521126760563, Blast_Score=138, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571796, Length=497, Percent_Identity=25.3521126760563, Blast_Score=138, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571794, Length=497, Percent_Identity=25.3521126760563, Blast_Score=138, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24638878, Length=429, Percent_Identity=27.2727272727273, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24638876, Length=429, Percent_Identity=27.2727272727273, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281360299, Length=335, Percent_Identity=28.0597014925373, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281360297, Length=335, Percent_Identity=28.0597014925373, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281360295, Length=335, Percent_Identity=28.0597014925373, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24586250, Length=335, Percent_Identity=28.0597014925373, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281360301, Length=331, Percent_Identity=28.0966767371601, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI45552499, Length=335, Percent_Identity=26.2686567164179, Blast_Score=92, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281360303, Length=331, Percent_Identity=26.2839879154079, Blast_Score=91, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 141368; Mature: 141237

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTTLGVKVDDLLRTRLKDAATRLERTPHWLIKQAIFAYLEKIEHGQLPAELSGHHGAT
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCH
ELADGAADPDESDGLHPFLEFAQSVQPQSVLRAAITAAYRRPEPECVPFLIGQARLPANI
HHCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHH
ANDVQAMASKLVEALRSKSTGGGVEGLIHEFSLSSQEGVALMCLAEALLRIPDRATRDAL
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
IRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSETGLSSALTRMIGKGGEPLI
HHHHCCCCCHHHHCCCCCHHEEEHHHEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCHHH
RKGVDMAMRLMGEQFVTGETISEALANSRKFEARGFRYSYDMLGEAATTEADAQRYYASY
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEHHHHCCHHCCHHHHHHHHHHH
EQAIHAIGKAAGGRGIYEGPGISIKLSALHPRYSRSQQERTMSELLPRVRALAILARRYD
HHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IGLNIDAEEADRLEISLDLLEALCFDPELQGWNGIGFVVQAYQKRCPFVIDYIVDLARRS
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
RHRIMVRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLGAPDAVYPQF
HHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
ATHNAHTLSAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHE
HCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHCCHHHCCCCEEEEECCCCHH
TLLAYLVRRLLENGANTSFVNRIADETVPVQDLVADPVDEAAKIVPLGAPHAKIPLPRNL
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCCHHHHHHEEECCCCCCCCCCCCCC
YGAERTNSMGLDLSNEHRLASLSSALLASANHPWRAAPMLEGNEIAVGRARDVRNPSDHR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHH
DLVGTVVEATPEHVSAALAHAVAAAPIWQATPVEARADCLARAADLLEAQMHTLMGLVVR
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAGKSLPNAVAEIREAIDFLRYYSSQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHH
AALAAGNTVLAKPAEQTPLIAAQAVRILREAGVPAGAVQLLPGDGETVGAALVADARTRA
HHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCCCEE
VMFTGSTEVARLINKTLSNRLDPDGKPIPLIAETGGQNAMIVDSSALAEQVVADVLQSSF
EEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHH
DSAGQRCSALRVLCLQDDVADRTLEMLTGAMKELAVGNPDRLSIDVGPVIDAEAKRGIDA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHCCHHH
HIASMREKGRKVTQMPMPDGCAAGTFVPPTLIELDNIDELKREVFGPVLHVVRYRRSALD
HHHHHHHCCCCEECCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
KLLEQIRATGYGLTLGIHTRIDETIAHVIGRAHVGNIYVNRNVIGAVVGVQPFGGEGLSG
HHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCCC
TGPKAGGALYLQRLLATRPAGLPKSLARTLMVDASQGAANGGQSAAQNGNAASDNPAAAL
CCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHEECCCCCCCCCCHHHCCCCCCCCCHHHHH
TTLRDWLIAEREPVLAARCDGYLSHIPAGATAVLAGPTGERNTYTLGARGTVLCVASTAS
HHHHHHHHHCCCCCHHHHHCHHHHHCCCCCEEEEECCCCCCCCEEECCCCEEEEEEECCC
GARVQFAAALATGNKALFEGAAGEQLYAALPPSLKQYASVKKNAEASFDAALFEGDSDEL
CCEEEEEHHHHCCCHHHHCCCCCCCEEECCCHHHHHHHHHHCCCCCCCCHHHCCCCHHHH
LALVKDIAKRAGPIVSVQGVAARALESGDEDYALERLLTERSVSVNTAAAGGNANLMTIG
HHHHHHHHHHCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCCCCEEEEC
>Mature Secondary Structure 
ASTTLGVKVDDLLRTRLKDAATRLERTPHWLIKQAIFAYLEKIEHGQLPAELSGHHGAT
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCH
ELADGAADPDESDGLHPFLEFAQSVQPQSVLRAAITAAYRRPEPECVPFLIGQARLPANI
HHCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHH
ANDVQAMASKLVEALRSKSTGGGVEGLIHEFSLSSQEGVALMCLAEALLRIPDRATRDAL
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
IRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSETGLSSALTRMIGKGGEPLI
HHHHCCCCCHHHHCCCCCHHEEEHHHEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCHHH
RKGVDMAMRLMGEQFVTGETISEALANSRKFEARGFRYSYDMLGEAATTEADAQRYYASY
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEHHHHCCHHCCHHHHHHHHHHH
EQAIHAIGKAAGGRGIYEGPGISIKLSALHPRYSRSQQERTMSELLPRVRALAILARRYD
HHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IGLNIDAEEADRLEISLDLLEALCFDPELQGWNGIGFVVQAYQKRCPFVIDYIVDLARRS
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
RHRIMVRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLGAPDAVYPQF
HHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
ATHNAHTLSAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHE
HCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHCCHHHCCCCEEEEECCCCHH
TLLAYLVRRLLENGANTSFVNRIADETVPVQDLVADPVDEAAKIVPLGAPHAKIPLPRNL
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCCHHHHHHEEECCCCCCCCCCCCCC
YGAERTNSMGLDLSNEHRLASLSSALLASANHPWRAAPMLEGNEIAVGRARDVRNPSDHR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHH
DLVGTVVEATPEHVSAALAHAVAAAPIWQATPVEARADCLARAADLLEAQMHTLMGLVVR
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAGKSLPNAVAEIREAIDFLRYYSSQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHH
AALAAGNTVLAKPAEQTPLIAAQAVRILREAGVPAGAVQLLPGDGETVGAALVADARTRA
HHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCCCEE
VMFTGSTEVARLINKTLSNRLDPDGKPIPLIAETGGQNAMIVDSSALAEQVVADVLQSSF
EEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHH
DSAGQRCSALRVLCLQDDVADRTLEMLTGAMKELAVGNPDRLSIDVGPVIDAEAKRGIDA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHCCHHH
HIASMREKGRKVTQMPMPDGCAAGTFVPPTLIELDNIDELKREVFGPVLHVVRYRRSALD
HHHHHHHCCCCEECCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
KLLEQIRATGYGLTLGIHTRIDETIAHVIGRAHVGNIYVNRNVIGAVVGVQPFGGEGLSG
HHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCCC
TGPKAGGALYLQRLLATRPAGLPKSLARTLMVDASQGAANGGQSAAQNGNAASDNPAAAL
CCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHEECCCCCCCCCCHHHCCCCCCCCCHHHHH
TTLRDWLIAEREPVLAARCDGYLSHIPAGATAVLAGPTGERNTYTLGARGTVLCVASTAS
HHHHHHHHHCCCCCHHHHHCHHHHHCCCCCEEEEECCCCCCCCEEECCCCEEEEEEECCC
GARVQFAAALATGNKALFEGAAGEQLYAALPPSLKQYASVKKNAEASFDAALFEGDSDEL
CCEEEEEHHHHCCCHHHHCCCCCCCEEECCCHHHHHHHHHHCCCCCCCCHHHCCCCHHHH
LALVKDIAKRAGPIVSVQGVAARALESGDEDYALERLLTERSVSVNTAAAGGNANLMTIG
HHHHHHHHHHCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]