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The map label for this gene is aidB [H]

Identifier: 186477672

GI number: 186477672

Start: 3280851

End: 3282524

Strand: Direct

Name: aidB [H]

Synonym: Bphy_2924

Alternate gene names: 186477672

Gene position: 3280851-3282524 (Clockwise)

Preceding gene: 186477670

Following gene: 186477678

Centisome position: 94.3

GC content: 67.38

Gene sequence:

>1674_bases
ATGGAACGGTTCGGCCCCGGCATCACGCATGAAGTGTCCAATCAGGCTCCCCCGCTCGCGAACTACAACCTGTTTACAAG
CGATGCCGCGCTGGCCGCCGCCGTCGAGCGCGAAGGCGCGGCGTGGCATCGGGAAGCGCTCACGCGCGACGGCGCCGCGC
TGACGACGCCCGAGATCCTCGCACTCGCCGAGCTGGCGAACCGCCACACGCCCGAACTCGCCGCCTTCAGCCCGCGCGGC
GAGCGCATCGACGCGCTCGAATTTCATCCCGCATGGCATACGCTGCTCGGCCTGTTGCGCCGTGAAGGACTGCACGCACT
GCCCTTCTCCGACCCGCAGCCGGGTGCGATGGTCGCGCGTTGCGCCGGCTATTTTCTGCACGCGCAACTCGAATCGGGCT
CACTGTGTCCGGTCACGATGACTTTCGCCAGCATTCCCGTGCTGCAGCGCGAACCCGGACTGTTCGCGACGTTGCGCGAC
AAGCTGTATTCGCGCGAGCACGATCCGCGCGACCTGCCGCTCGAGCAGAAGACCTCGATGATGATCGGCATGGGCATGAC
GGAGAAGCAAGGCGGCTCGGATGTGCGCAGCAACCGCACCCAGGCGTTTGCAGCAAGCGGCAGCGGACGCGGCGCCGGCT
ACCGGCTGGTCGGACACAAATGGTTTTTCTCGGCGCCGCAGTGCGACGCCCACCTGGTCCTCGCACGCACCGGCGATCAC
GAAGGCCTCTCCTGCTTCTTCGTGCCGCGCTTCGCGCCGGACGGCAGCAAGAACGCGGTGCGCATCCAGCGTCTGAAGGA
CAAGCTCGGCAACCGCTCGAACGCGAGCAGTGAAGTCGAGTTCTTCGACGCCTGGGGCATCATGATCGGCGACGAGGGAC
GCGGCGTGCCGACCATCATCGAAATGGCGAATTACACGCGGCTCGATTGCGTGATCGGCAGCGCGGCGCTGATGCGCGCG
GCGCTCGTGCAGGCGATTCACCATGCGCGCCATCGCAGCGCGTTCGGCAAACATCTCGCCGATCAGCCGTTGATGCGCAA
TGTGCTCGCTGACCTGGCGCTCGAATCGGAGGCGGCGACCGTGCTGTTCATGCGCCTCGCGCGCGCCTTCGAAGACATGA
CGAACGCCCCGGAAGAACGCGCGTGGCGGCGCCTCGTCACGCCGGCGGCGAAGTACTGGGTCTGCAAGCGCACGCTCGAA
TTCACGGGCGAAGCGATGGAAGTCTGGGGCGGCAACGGTTACGTCGAAGAAGGACCGATGGCGCGCTTCTACCGCGAAGC
ACCCGTAAATTCGATCTGGGAAGGCTCGGGCAACGTGATGTGTCTTGACGTGCTGCGCGCGATGGAGCGCGAGCCGGGCG
CCGCGCAGGCCCTGCTCGCCGCGTGGCGAGCGCACGCGCAAGCGCACCCGGCGTTGAACGCCGCGCTCGACCGTTTGACG
GCCGCGTCGACGTCCGCGCCCGAGACGCGCGAAGTCTCGGCGCGCCGCATCGCCCAGCAGATCGTGCTGATCGCGCAGGC
CGTGCTGCTCGTGCAACACGCGCCCTCGTTCGTCGCCGATGCGTACATCGCGACGCGGCTGGGCGAAGGCTGTGGCGAAA
GCGGACGCGTGTACGGCACGCTGCCCGCCGCCTTCGATCACGCGGCTATCGCGAATCGCGCATTTCCGGCCTGA

Upstream 100 bases:

>100_bases
ACAGTCTGTTGCGCGCTGCCTCTGTTTCATTCTGCTGGCGGGTTTTAAGCAAACGGTAGCGTCGACACCGGACGGCGCGT
GCATCGAAGGGAGACATCAG

Downstream 100 bases:

>100_bases
CTATCGAGCAAGCAGGACATCGAGTAGAACACCGGAGACACAACCAGATGAAGCACGACCTGCCGGAGCTCGCGGCACTG
CAAGCACTGTTGCGCGAGCA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MERFGPGITHEVSNQAPPLANYNLFTSDAALAAAVEREGAAWHREALTRDGAALTTPEILALAELANRHTPELAAFSPRG
ERIDALEFHPAWHTLLGLLRREGLHALPFSDPQPGAMVARCAGYFLHAQLESGSLCPVTMTFASIPVLQREPGLFATLRD
KLYSREHDPRDLPLEQKTSMMIGMGMTEKQGGSDVRSNRTQAFAASGSGRGAGYRLVGHKWFFSAPQCDAHLVLARTGDH
EGLSCFFVPRFAPDGSKNAVRIQRLKDKLGNRSNASSEVEFFDAWGIMIGDEGRGVPTIIEMANYTRLDCVIGSAALMRA
ALVQAIHHARHRSAFGKHLADQPLMRNVLADLALESEAATVLFMRLARAFEDMTNAPEERAWRRLVTPAAKYWVCKRTLE
FTGEAMEVWGGNGYVEEGPMARFYREAPVNSIWEGSGNVMCLDVLRAMEREPGAAQALLAAWRAHAQAHPALNAALDRLT
AASTSAPETREVSARRIAQQIVLIAQAVLLVQHAPSFVADAYIATRLGEGCGESGRVYGTLPAAFDHAAIANRAFPA

Sequences:

>Translated_557_residues
MERFGPGITHEVSNQAPPLANYNLFTSDAALAAAVEREGAAWHREALTRDGAALTTPEILALAELANRHTPELAAFSPRG
ERIDALEFHPAWHTLLGLLRREGLHALPFSDPQPGAMVARCAGYFLHAQLESGSLCPVTMTFASIPVLQREPGLFATLRD
KLYSREHDPRDLPLEQKTSMMIGMGMTEKQGGSDVRSNRTQAFAASGSGRGAGYRLVGHKWFFSAPQCDAHLVLARTGDH
EGLSCFFVPRFAPDGSKNAVRIQRLKDKLGNRSNASSEVEFFDAWGIMIGDEGRGVPTIIEMANYTRLDCVIGSAALMRA
ALVQAIHHARHRSAFGKHLADQPLMRNVLADLALESEAATVLFMRLARAFEDMTNAPEERAWRRLVTPAAKYWVCKRTLE
FTGEAMEVWGGNGYVEEGPMARFYREAPVNSIWEGSGNVMCLDVLRAMEREPGAAQALLAAWRAHAQAHPALNAALDRLT
AASTSAPETREVSARRIAQQIVLIAQAVLLVQHAPSFVADAYIATRLGEGCGESGRVYGTLPAAFDHAAIANRAFPA
>Mature_557_residues
MERFGPGITHEVSNQAPPLANYNLFTSDAALAAAVEREGAAWHREALTRDGAALTTPEILALAELANRHTPELAAFSPRG
ERIDALEFHPAWHTLLGLLRREGLHALPFSDPQPGAMVARCAGYFLHAQLESGSLCPVTMTFASIPVLQREPGLFATLRD
KLYSREHDPRDLPLEQKTSMMIGMGMTEKQGGSDVRSNRTQAFAASGSGRGAGYRLVGHKWFFSAPQCDAHLVLARTGDH
EGLSCFFVPRFAPDGSKNAVRIQRLKDKLGNRSNASSEVEFFDAWGIMIGDEGRGVPTIIEMANYTRLDCVIGSAALMRA
ALVQAIHHARHRSAFGKHLADQPLMRNVLADLALESEAATVLFMRLARAFEDMTNAPEERAWRRLVTPAAKYWVCKRTLE
FTGEAMEVWGGNGYVEEGPMARFYREAPVNSIWEGSGNVMCLDVLRAMEREPGAAQALLAAWRAHAQAHPALNAALDRLT
AASTSAPETREVSARRIAQQIVLIAQAVLLVQHAPSFVADAYIATRLGEGCGESGRVYGTLPAAFDHAAIANRAFPA

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=275, Percent_Identity=27.6363636363636, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI226958414, Length=277, Percent_Identity=27.4368231046931, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI4557233, Length=256, Percent_Identity=28.125, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI4501859, Length=363, Percent_Identity=26.1707988980716, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI7656849, Length=272, Percent_Identity=27.5735294117647, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI187960098, Length=280, Percent_Identity=25.7142857142857, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI4557231, Length=280, Percent_Identity=25.7142857142857, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI4557235, Length=374, Percent_Identity=22.9946524064171, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4501857, Length=272, Percent_Identity=25.7352941176471, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI76496475, Length=374, Percent_Identity=22.9946524064171, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082384, Length=521, Percent_Identity=49.7120921305182, Blast_Score=469, Evalue=1e-133,
Organism=Escherichia coli, GI1786223, Length=346, Percent_Identity=25.1445086705202, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86563383, Length=498, Percent_Identity=30.7228915662651, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI86563381, Length=498, Percent_Identity=30.7228915662651, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17538396, Length=296, Percent_Identity=29.3918918918919, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17508101, Length=305, Percent_Identity=25.2459016393443, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17506239, Length=273, Percent_Identity=24.5421245421245, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=279, Percent_Identity=29.7491039426523, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17551932, Length=272, Percent_Identity=29.4117647058824, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=355, Percent_Identity=24.7887323943662, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17569725, Length=273, Percent_Identity=22.7106227106227, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21355753, Length=406, Percent_Identity=26.1083743842365, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646207, Length=265, Percent_Identity=24.9056603773585, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356377, Length=273, Percent_Identity=26.3736263736264, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24660351, Length=276, Percent_Identity=25.7246376811594, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 60696; Mature: 60696

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERFGPGITHEVSNQAPPLANYNLFTSDAALAAAVEREGAAWHREALTRDGAALTTPEIL
CCCCCCCCCHHHCCCCCCCCCCCEEECCHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHH
ALAELANRHTPELAAFSPRGERIDALEFHPAWHTLLGLLRREGLHALPFSDPQPGAMVAR
HHHHHHCCCCCCCEEECCCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
CAGYFLHAQLESGSLCPVTMTFASIPVLQREPGLFATLRDKLYSREHDPRDLPLEQKTSM
HHHHHEEEEECCCCCCEEEHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHCCE
MIGMGMTEKQGGSDVRSNRTQAFAASGSGRGAGYRLVGHKWFFSAPQCDAHLVLARTGDH
EEECCCCCCCCCCCHHCCCCCEEEECCCCCCCCEEEECCEEECCCCCCCCEEEEEECCCC
EGLSCFFVPRFAPDGSKNAVRIQRLKDKLGNRSNASSEVEFFDAWGIMIGDEGRGVPTII
CCEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCCCHHHH
EMANYTRLDCVIGSAALMRAALVQAIHHARHRSAFGKHLADQPLMRNVLADLALESEAAT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHH
VLFMRLARAFEDMTNAPEERAWRRLVTPAAKYWVCKRTLEFTGEAMEVWGGNGYVEEGPM
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCH
ARFYREAPVNSIWEGSGNVMCLDVLRAMEREPGAAQALLAAWRAHAQAHPALNAALDRLT
HHHHHHCCCCHHHCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
AASTSAPETREVSARRIAQQIVLIAQAVLLVQHAPSFVADAYIATRLGEGCGESGRVYGT
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEE
LPAAFDHAAIANRAFPA
CCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MERFGPGITHEVSNQAPPLANYNLFTSDAALAAAVEREGAAWHREALTRDGAALTTPEIL
CCCCCCCCCHHHCCCCCCCCCCCEEECCHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHH
ALAELANRHTPELAAFSPRGERIDALEFHPAWHTLLGLLRREGLHALPFSDPQPGAMVAR
HHHHHHCCCCCCCEEECCCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
CAGYFLHAQLESGSLCPVTMTFASIPVLQREPGLFATLRDKLYSREHDPRDLPLEQKTSM
HHHHHEEEEECCCCCCEEEHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHCCE
MIGMGMTEKQGGSDVRSNRTQAFAASGSGRGAGYRLVGHKWFFSAPQCDAHLVLARTGDH
EEECCCCCCCCCCCHHCCCCCEEEECCCCCCCCEEEECCEEECCCCCCCCEEEEEECCCC
EGLSCFFVPRFAPDGSKNAVRIQRLKDKLGNRSNASSEVEFFDAWGIMIGDEGRGVPTII
CCEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCCCHHHH
EMANYTRLDCVIGSAALMRAALVQAIHHARHRSAFGKHLADQPLMRNVLADLALESEAAT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHH
VLFMRLARAFEDMTNAPEERAWRRLVTPAAKYWVCKRTLEFTGEAMEVWGGNGYVEEGPM
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCH
ARFYREAPVNSIWEGSGNVMCLDVLRAMEREPGAAQALLAAWRAHAQAHPALNAALDRLT
HHHHHHCCCCHHHCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
AASTSAPETREVSARRIAQQIVLIAQAVLLVQHAPSFVADAYIATRLGEGCGESGRVYGT
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEE
LPAAFDHAAIANRAFPA
CCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]