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The map label for this gene is ywbI [H]

Identifier: 186477670

GI number: 186477670

Start: 3277563

End: 3278522

Strand: Direct

Name: ywbI [H]

Synonym: Bphy_2922

Alternate gene names: 186477670

Gene position: 3277563-3278522 (Clockwise)

Preceding gene: 186477656

Following gene: 186477672

Centisome position: 94.2

GC content: 65.94

Gene sequence:

>960_bases
ATGGAACTGCGCGCGCTTCGCTATTTCGTCGAGGTTGTACGGCAGCAGAGCTTCACCGTCGCGGCCGAGCAGATGTTCGT
CACACAGCCGACCATCAGCAAGATGGTGAAGTCGCTGGAGGACGAAATCGGCTCGCCGCTGCTGTTGCGCGACGGTCGCC
AGATGGTGCTGACGGACGCCGGCCGCATCGTCTATCAGCGCGGACAGGATGTGCTCGCCGCCTACGCACAGTTGCAGGCG
GAACTGAACGATCTCGACAAGCTAGGGCGCGGCGAACTGACGATCGGCATTCCGCCAATGGGCGGCTCGCTCTTCACGCC
TGCCATCGCCGCGTTCCGGCAGCGTTATCCGAAAGTGGAGCTGAAGCTGTTCGAGCAGGGTTCGAAGGCCATCGAGGCCG
CATTGATTTCTGGCGAGCTGGAGCTCGGCGGCGTCCTTCAGCCCGTCGACGAACTGGTTGACGTGCTGCCGATGACCCGC
CAGGTGCTTTGGCTCGTCGCGCGTCACGGCTCGCGCTGGGATGCGCTGCAGGAAGTGCCGCTCGCCGGTCTCGCGCAGGA
ACCGTTCGTGTTCTACGGCGAAAGCCTCGCGCTGAACGATGTCGTGCTGGCGGCATGCCGCGCGGCGGGCTTTGCGCCGA
CCATCGTCGGGCGCAGCGGACACTGGGATTTCATGGCGGCACTGGTGCTGGCGGGCGTCGGCATTGCGCTGTTGCCCGCG
CCGTATTGCCGGCGGCTCGATGCCGCGCAGTTCACGTGCCGGCCCGTCGTCGCGCCGGAAATTCCATGGGAAATGGCGAT
CGGCTGGCGGCGCAACGGCTATCTGTCGCATGCGGCGCGCGCGTGGCTCGAGGTCGCGCGCGAGACGCTGCCGGGTTTGA
GCACCGACAACTTCACACATCCGCCCACGTTCGATCTGCCCGCAGCGTCGCCCGATCGAGCGACGCCGTCGCTGAAATAG

Upstream 100 bases:

>100_bases
TGACTTTCGGATGAGATTCAGTATAGGGTGCACTGCACCATAAATATAATGACTTAGAATTATCCGCTTCATTCCAATTT
GGAATTTCGAGGGCATAAAC

Downstream 100 bases:

>100_bases
AAAATGCCGCACGGTCTGCACCGGGCGGCATGCTGTCCGGCGTTGGTTGGCCGGCGGACGACGCTTACTGCGCTTGCGCG
TCGGTGAATTCGATCCGCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MELRALRYFVEVVRQQSFTVAAEQMFVTQPTISKMVKSLEDEIGSPLLLRDGRQMVLTDAGRIVYQRGQDVLAAYAQLQA
ELNDLDKLGRGELTIGIPPMGGSLFTPAIAAFRQRYPKVELKLFEQGSKAIEAALISGELELGGVLQPVDELVDVLPMTR
QVLWLVARHGSRWDALQEVPLAGLAQEPFVFYGESLALNDVVLAACRAAGFAPTIVGRSGHWDFMAALVLAGVGIALLPA
PYCRRLDAAQFTCRPVVAPEIPWEMAIGWRRNGYLSHAARAWLEVARETLPGLSTDNFTHPPTFDLPAASPDRATPSLK

Sequences:

>Translated_319_residues
MELRALRYFVEVVRQQSFTVAAEQMFVTQPTISKMVKSLEDEIGSPLLLRDGRQMVLTDAGRIVYQRGQDVLAAYAQLQA
ELNDLDKLGRGELTIGIPPMGGSLFTPAIAAFRQRYPKVELKLFEQGSKAIEAALISGELELGGVLQPVDELVDVLPMTR
QVLWLVARHGSRWDALQEVPLAGLAQEPFVFYGESLALNDVVLAACRAAGFAPTIVGRSGHWDFMAALVLAGVGIALLPA
PYCRRLDAAQFTCRPVVAPEIPWEMAIGWRRNGYLSHAARAWLEVARETLPGLSTDNFTHPPTFDLPAASPDRATPSLK
>Mature_319_residues
MELRALRYFVEVVRQQSFTVAAEQMFVTQPTISKMVKSLEDEIGSPLLLRDGRQMVLTDAGRIVYQRGQDVLAAYAQLQA
ELNDLDKLGRGELTIGIPPMGGSLFTPAIAAFRQRYPKVELKLFEQGSKAIEAALISGELELGGVLQPVDELVDVLPMTR
QVLWLVARHGSRWDALQEVPLAGLAQEPFVFYGESLALNDVVLAACRAAGFAPTIVGRSGHWDFMAALVLAGVGIALLPA
PYCRRLDAAQFTCRPVVAPEIPWEMAIGWRRNGYLSHAARAWLEVARETLPGLSTDNFTHPPTFDLPAASPDRATPSLK

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=286, Percent_Identity=30.0699300699301, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787879, Length=287, Percent_Identity=29.616724738676, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790399, Length=297, Percent_Identity=28.956228956229, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788887, Length=303, Percent_Identity=29.7029702970297, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788297, Length=253, Percent_Identity=27.6679841897233, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788748, Length=292, Percent_Identity=26.027397260274, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI145693105, Length=286, Percent_Identity=23.7762237762238, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367136, Length=248, Percent_Identity=25.8064516129032, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789506, Length=287, Percent_Identity=23.6933797909408, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787530, Length=295, Percent_Identity=25.7627118644068, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786401, Length=119, Percent_Identity=37.8151260504202, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789173, Length=123, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693193, Length=123, Percent_Identity=31.7073170731707, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=28.6713286713287, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790208, Length=258, Percent_Identity=25.968992248062, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786713, Length=279, Percent_Identity=26.5232974910394, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788296, Length=243, Percent_Identity=23.4567901234568, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34962; Mature: 34962

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRALRYFVEVVRQQSFTVAAEQMFVTQPTISKMVKSLEDEIGSPLLLRDGRQMVLTDA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCEEEEECC
GRIVYQRGQDVLAAYAQLQAELNDLDKLGRGELTIGIPPMGGSLFTPAIAAFRQRYPKVE
CHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHH
LKLFEQGSKAIEAALISGELELGGVLQPVDELVDVLPMTRQVLWLVARHGSRWDALQEVP
HHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
LAGLAQEPFVFYGESLALNDVVLAACRAAGFAPTIVGRSGHWDFMAALVLAGVGIALLPA
CCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCHHHHHCC
PYCRRLDAAQFTCRPVVAPEIPWEMAIGWRRNGYLSHAARAWLEVARETLPGLSTDNFTH
HHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
PPTFDLPAASPDRATPSLK
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MELRALRYFVEVVRQQSFTVAAEQMFVTQPTISKMVKSLEDEIGSPLLLRDGRQMVLTDA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCEEEEECC
GRIVYQRGQDVLAAYAQLQAELNDLDKLGRGELTIGIPPMGGSLFTPAIAAFRQRYPKVE
CHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHH
LKLFEQGSKAIEAALISGELELGGVLQPVDELVDVLPMTRQVLWLVARHGSRWDALQEVP
HHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
LAGLAQEPFVFYGESLALNDVVLAACRAAGFAPTIVGRSGHWDFMAALVLAGVGIALLPA
CCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCHHHHHCC
PYCRRLDAAQFTCRPVVAPEIPWEMAIGWRRNGYLSHAARAWLEVARETLPGLSTDNFTH
HHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
PPTFDLPAASPDRATPSLK
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]