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The map label for this gene is ompR [H]

Identifier: 186477531

GI number: 186477531

Start: 3130618

End: 3131355

Strand: Direct

Name: ompR [H]

Synonym: Bphy_2783

Alternate gene names: 186477531

Gene position: 3130618-3131355 (Clockwise)

Preceding gene: 186477526

Following gene: 186477532

Centisome position: 89.98

GC content: 65.18

Gene sequence:

>738_bases
ATGAATCCACAGGTCCTCATCGTCGACGACGATCCCGTCGTGCGCGATCTCCTTTGTCGCTTCCTGCAATCGAACGGCTA
CGATGCATCGGTGCTGCATGACGGCACGCATCTGCAACGGCGTCTCGAACGGGAGCGGCCTTCCGTCGTCGTGCTCGACA
TCATGATGCCGAACACGGACGGCCTGCGCGCGCTCACCGCGTTGCGCGCCGCCGGCGACGACATTCCCGTGATCTTCGTG
ACGGCGCGCGGCACGGTGGCCGACCGCATCATTGGCCTGTCGCTCGGCGCCGACGACTATCTGACGAAACCATTCGATCC
GCGCGAGCTGCTCGCGCGCATCCAGACGGTGCTCCGCCGGCGCGGTCCCGCGACGACGAGCGCTCCCGAGGCGCGCAAGC
GCTATCGCTTCGGTCCGTTCGAACTGGATTTCGCGACGCGCACGCTGTCGCGCGACGAAACGCGCGTCACGCTGCGCGAC
AGCGAGTTCGCGCTGCTCAAAATCTTCGTCAACAATCCGTACAAGGTGCTGTCGCGCGTGCTGATTCACGATCTCGTTCA
TCGCGACGACCTGCCTTTCCGCGACCGCAGCCTCGATGTGCCGATCTGGCGTCTGCGGCGGGTGATCGAAAACGATCCGT
CCAATCCGTGCTACGTGCAGACCGTGCGCGGCAAAGGCTATGTGTTCGTCCCCGATGCGGATCCGAACGGCGCGCCCTTC
GCCGCCGATCCCGCGTGA

Upstream 100 bases:

>100_bases
GTGTCGCGCCGCGCCGCGCGCCGGCAGCTTGAGAGTTTGAGTAAGTGTTGGTAAGGAAGACTTCGGCCGCCGAGCCACGA
TGCCGGACTAGAATTTCGGT

Downstream 100 bases:

>100_bases
TCGCCGCGTGACCCGTATCAGGAATCCGCTGAATACGCTGTTCGGCCGGATGGCATTGCTTTCGTCGGCGGTGCTGTTTG
CGATTCAGGCCGGCTGGTTC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MNPQVLIVDDDPVVRDLLCRFLQSNGYDASVLHDGTHLQRRLERERPSVVVLDIMMPNTDGLRALTALRAAGDDIPVIFV
TARGTVADRIIGLSLGADDYLTKPFDPRELLARIQTVLRRRGPATTSAPEARKRYRFGPFELDFATRTLSRDETRVTLRD
SEFALLKIFVNNPYKVLSRVLIHDLVHRDDLPFRDRSLDVPIWRLRRVIENDPSNPCYVQTVRGKGYVFVPDADPNGAPF
AADPA

Sequences:

>Translated_245_residues
MNPQVLIVDDDPVVRDLLCRFLQSNGYDASVLHDGTHLQRRLERERPSVVVLDIMMPNTDGLRALTALRAAGDDIPVIFV
TARGTVADRIIGLSLGADDYLTKPFDPRELLARIQTVLRRRGPATTSAPEARKRYRFGPFELDFATRTLSRDETRVTLRD
SEFALLKIFVNNPYKVLSRVLIHDLVHRDDLPFRDRSLDVPIWRLRRVIENDPSNPCYVQTVRGKGYVFVPDADPNGAPF
AADPA
>Mature_245_residues
MNPQVLIVDDDPVVRDLLCRFLQSNGYDASVLHDGTHLQRRLERERPSVVVLDIMMPNTDGLRALTALRAAGDDIPVIFV
TARGTVADRIIGLSLGADDYLTKPFDPRELLARIQTVLRRRGPATTSAPEARKRYRFGPFELDFATRTLSRDETRVTLRD
SEFALLKIFVNNPYKVLSRVLIHDLVHRDDLPFRDRSLDVPIWRLRRVIENDPSNPCYVQTVRGKGYVFVPDADPNGAPF
AADPA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=44.206008583691, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=36.0169491525424, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=34.6320346320346, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=35.4978354978355, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1788394, Length=232, Percent_Identity=33.6206896551724, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=34.9775784753363, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1787229, Length=238, Percent_Identity=34.453781512605, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=35.7446808510638, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=33.1877729257642, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=31.858407079646, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=31.140350877193, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=32.3275862068966, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=29.3333333333333, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI145693140, Length=240, Percent_Identity=30, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=35.6521739130435, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788905, Length=122, Percent_Identity=33.6065573770492, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=34.2342342342342, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=36.6336633663366, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI145693157, Length=100, Percent_Identity=37, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790437, Length=117, Percent_Identity=30.7692307692308, Blast_Score=61, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=120, Percent_Identity=35, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27716; Mature: 27716

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPQVLIVDDDPVVRDLLCRFLQSNGYDASVLHDGTHLQRRLERERPSVVVLDIMMPNTD
CCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCEEEEEEEECCCC
GLRALTALRAAGDDIPVIFVTARGTVADRIIGLSLGADDYLTKPFDPRELLARIQTVLRR
HHHHHHHHHHCCCCCCEEEEEECCCHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
RGPATTSAPEARKRYRFGPFELDFATRTLSRDETRVTLRDSEFALLKIFVNNPYKVLSRV
CCCCCCCCHHHHHHCCCCCEEEEHHHHHCCCCCEEEEEECCCEEEEEEEECCHHHHHHHH
LIHDLVHRDDLPFRDRSLDVPIWRLRRVIENDPSNPCYVQTVRGKGYVFVPDADPNGAPF
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCC
AADPA
CCCCC
>Mature Secondary Structure
MNPQVLIVDDDPVVRDLLCRFLQSNGYDASVLHDGTHLQRRLERERPSVVVLDIMMPNTD
CCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCEEEEEEEECCCC
GLRALTALRAAGDDIPVIFVTARGTVADRIIGLSLGADDYLTKPFDPRELLARIQTVLRR
HHHHHHHHHHCCCCCCEEEEEECCCHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
RGPATTSAPEARKRYRFGPFELDFATRTLSRDETRVTLRDSEFALLKIFVNNPYKVLSRV
CCCCCCCCHHHHHHCCCCCEEEEHHHHHCCCCCEEEEEECCCEEEEEEEECCHHHHHHHH
LIHDLVHRDDLPFRDRSLDVPIWRLRRVIENDPSNPCYVQTVRGKGYVFVPDADPNGAPF
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCC
AADPA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]