Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 186477526

GI number: 186477526

Start: 3127502

End: 3128248

Strand: Direct

Name: ompR [H]

Synonym: Bphy_2778

Alternate gene names: 186477526

Gene position: 3127502-3128248 (Clockwise)

Preceding gene: 186477525

Following gene: 186477531

Centisome position: 89.89

GC content: 65.06

Gene sequence:

>747_bases
ATGAACTCATCCATTATGGTCGTCGACGACGACCCCGTCGTCCGCGACATCGTGCGCGACTATCTGCAAGGCCGGGGCTT
CACGGTATCCGTGCTCGAGAATGGCATGGCTTTGCAGCAGGCACTTCAGCTCGAGCGGCCTGCCCTCGTCGTGCTCGACA
TCATGATGCCGGAGCTCGACGGCATCAGCGCACTCCGCGCGCTGCGCCTCGCGGGCGACAGCATTCCCGTGATCCTGCTC
ACCGCACGCGCGGATGTGATCGATCGCGTGATCGGCCTCGAACTCGGCGCGGATGACTACCTCGGCAAACCGTTCGATCC
GAGCGAGCTCGTCGCGCGCATTCGCAGCGTGCTGCGCCGCCGTGAAAGCGCGGCGCCGGGCGCGCCTGAAAATCGCGCGC
CATATCGCTTCGGCCGCTTCGAAGTGAATTTCCCCGCGCGCGAACTGCGCCGCGACGGCGAACGCATTGCGCTGCGCTCC
AGCGAATTCGCGATGCTCAAGGTGTTCGTCTCCCACGCGATGACGGTGCTCACGCGCGCGCAGCTCCTCGAAAAGCTGCA
CGGCAGCACCGATACGCATCGCAATCGCAGCCTCGACGTGTCCATCTGGCGTCTGCGCCGGCTGATCGAAGTCGATCCGT
CCGAGCCGCGCTACGTGCAGACGGTATGGGGCAAAGGCTATGTGTTCGTGCCGGACGGCGAGATCGGCGCAGCGGAACGA
TACGACGCACCCGTCGCGAATCTCTGA

Upstream 100 bases:

>100_bases
TGCCAGCCGCAGACAAAAAGAAACGCACCTCTTACTCCCGAAAGATTTGGAAAGCACCCCAACCTTCCGCGTGAAGTGCC
AAATCACTACTATCGCGAGG

Downstream 100 bases:

>100_bases
CGCGACGCAGGCCGCGACATTAAGAACAAGGCGCGGGCCATCGAACCCCGCGCACAGGATCAGAACGTCAACACGCTCAT
GAACATGCGCTGCAGCCAGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MNSSIMVVDDDPVVRDIVRDYLQGRGFTVSVLENGMALQQALQLERPALVVLDIMMPELDGISALRALRLAGDSIPVILL
TARADVIDRVIGLELGADDYLGKPFDPSELVARIRSVLRRRESAAPGAPENRAPYRFGRFEVNFPARELRRDGERIALRS
SEFAMLKVFVSHAMTVLTRAQLLEKLHGSTDTHRNRSLDVSIWRLRRLIEVDPSEPRYVQTVWGKGYVFVPDGEIGAAER
YDAPVANL

Sequences:

>Translated_248_residues
MNSSIMVVDDDPVVRDIVRDYLQGRGFTVSVLENGMALQQALQLERPALVVLDIMMPELDGISALRALRLAGDSIPVILL
TARADVIDRVIGLELGADDYLGKPFDPSELVARIRSVLRRRESAAPGAPENRAPYRFGRFEVNFPARELRRDGERIALRS
SEFAMLKVFVSHAMTVLTRAQLLEKLHGSTDTHRNRSLDVSIWRLRRLIEVDPSEPRYVQTVWGKGYVFVPDGEIGAAER
YDAPVANL
>Mature_248_residues
MNSSIMVVDDDPVVRDIVRDYLQGRGFTVSVLENGMALQQALQLERPALVVLDIMMPELDGISALRALRLAGDSIPVILL
TARADVIDRVIGLELGADDYLGKPFDPSELVARIRSVLRRRESAAPGAPENRAPYRFGRFEVNFPARELRRDGERIALRS
SEFAMLKVFVSHAMTVLTRAQLLEKLHGSTDTHRNRSLDVSIWRLRRLIEVDPSEPRYVQTVWGKGYVFVPDGEIGAAER
YDAPVANL

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=47.6394849785408, Blast_Score=218, Evalue=3e-58,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=36.3247863247863, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=33.4763948497854, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=35.3448275862069, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=35.9307359307359, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=32.618025751073, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=32.1428571428571, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=37.9310344827586, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=36.3636363636364, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=34.468085106383, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=32.8888888888889, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=33.4801762114537, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=30.3030303030303, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=29.2035398230088, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=36.5853658536585, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788550, Length=161, Percent_Identity=32.9192546583851, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790437, Length=140, Percent_Identity=35.7142857142857, Blast_Score=71, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322000, Length=134, Percent_Identity=31.3432835820896, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27777; Mature: 27777

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00572 GLYCOSYL_HYDROL_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSIMVVDDDPVVRDIVRDYLQGRGFTVSVLENGMALQQALQLERPALVVLDIMMPELD
CCCCEEEECCCHHHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHHCCCCEEEEEHHHCCCC
GISALRALRLAGDSIPVILLTARADVIDRVIGLELGADDYLGKPFDPSELVARIRSVLRR
HHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
RESAAPGAPENRAPYRFGRFEVNFPARELRRDGERIALRSSEFAMLKVFVSHAMTVLTRA
HHHCCCCCCCCCCCCEECCEEECCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
QLLEKLHGSTDTHRNRSLDVSIWRLRRLIEVDPSEPRYVQTVWGKGYVFVPDGEIGAAER
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCCCHH
YDAPVANL
CCCCCCCC
>Mature Secondary Structure
MNSSIMVVDDDPVVRDIVRDYLQGRGFTVSVLENGMALQQALQLERPALVVLDIMMPELD
CCCCEEEECCCHHHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHHCCCCEEEEEHHHCCCC
GISALRALRLAGDSIPVILLTARADVIDRVIGLELGADDYLGKPFDPSELVARIRSVLRR
HHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
RESAAPGAPENRAPYRFGRFEVNFPARELRRDGERIALRSSEFAMLKVFVSHAMTVLTRA
HHHCCCCCCCCCCCCEECCEEECCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
QLLEKLHGSTDTHRNRSLDVSIWRLRRLIEVDPSEPRYVQTVWGKGYVFVPDGEIGAAER
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCCCHH
YDAPVANL
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]