Click here to switch to the map view.

The map label for this gene is degQ [H]

Identifier: 186477493

GI number: 186477493

Start: 3099785

End: 3100996

Strand: Direct

Name: degQ [H]

Synonym: Bphy_2745

Alternate gene names: 186477493

Gene position: 3099785-3100996 (Clockwise)

Preceding gene: 186477485

Following gene: 186477523

Centisome position: 89.1

GC content: 63.12

Gene sequence:

>1212_bases
ATGCTCAGACGCTTTTGGCTGTTCTTCGCCCAGGCGGTGACCGTGCTGCTGGCGCTGATGTTCATTATTGCGACCCTCAA
ACCGCAGTGGCTACAGCGTCAAGGGCAGTTCGGCAAGCAACTGGCCGAGCCGATCGTCGCGCTCCGAGAGGTGGCACCCG
GAATGGGCAGCGGCGGCTCGGTCCAGAATTCCTACGCCGACGCGGCGCAAAAGGCAATGCCCGCCGTCGTCAACGTGTTC
TCCAGCAAGGACGGCTCGCTGCCGCCCGACCCGCGCGCGAAAGATCCTCTCTTCCGCTACTTCTTCGGCGACAAGAACAA
AAAGCAGCAGCAAGAGCAACCCGCGGCCAACCTCGGCTCGGGAGTCATCGTGAGTTCGGAAGGTTACATTCTAACGAACC
AGCATGTCGTCGATGGCGCGGACCAGATCGAAATCGCGCTCGCCGACGGCCGCACGACCAACGCAAAGGTGATCGGCGTC
GATCCCGAGACGGATCTGGCCGTGCTCAAGGTCAATATGACCAATCTGCCCACCATCACGCTCGGCCGCATGGACCAGAC
GCGCGTCGGCGACGTGGTGCTCGCAATCGGCAATCCGTTCGGCGTCGGGCAGACGGTGACGATGGGCATCGTCAGCGCGC
TCGGCCGCAATCACCTCGGCATCAATACGTTCGAAAACTTCATCCAGACCGACGCGCCAATCAATCCCGGCAACTCGGGC
GGCGCGCTGGTCGACGTGAACGGCAATCTGCTCGGCATCAATACGGCGATTTATTCGCGCTCGGGCGGTTCACTCGGCAT
CGGCTTCGCGATCCCCGTGTCGACGGCACGCAGCGTGCTGGAGAGCATCATCACGACGGGCACGGTAACGCGCGGCTGGA
TCGGCGTCGAACCACAGGACGTCACGCCGGAAATCGCCGAGTCGTTCGGGCTCGATCAGAAGTCGGGCGCGATCGTCGCG
GGTGTGCTGAAAGGCGGCCCCGCCGACAAGGCGGGCATCAAGCCCGGCGACATCCTGGTGTCGGTCAACGGTCAGGACAT
CACCGATACGACGCGCCTCCTGAACGTGATCGCGCAGATCAAGCCCGGCACCGACGCGAAGGTGCACCTGGTGCGCAAGA
ACAAGGAAATGGATCTGACGGTGATGATCGGCAAGCGCCCGCCGCCTCCGAAACAGCCTTCGGATGAAGGTGACGACGAA
GACGGCGGCTGA

Upstream 100 bases:

>100_bases
CAGACCGTTCGGGCAATAGTCCTTGAAGCGCGAGGTTTCAAGAAGATTGTTCAAGTACAATTCGAGTTCGATCCGATCCA
TATACACCTCTAATTTTCAG

Downstream 100 bases:

>100_bases
CGTCTCACTGAAGGTTCAGGCCGCGCACGCAAACAAAATGGGCAGTCTCCAACGGAGCACTGCCCTTTTTGTTGCTGTCT
GACCGCATGCGGTTGAGGAA

Product: 2-alkenal reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MLRRFWLFFAQAVTVLLALMFIIATLKPQWLQRQGQFGKQLAEPIVALREVAPGMGSGGSVQNSYADAAQKAMPAVVNVF
SSKDGSLPPDPRAKDPLFRYFFGDKNKKQQQEQPAANLGSGVIVSSEGYILTNQHVVDGADQIEIALADGRTTNAKVIGV
DPETDLAVLKVNMTNLPTITLGRMDQTRVGDVVLAIGNPFGVGQTVTMGIVSALGRNHLGINTFENFIQTDAPINPGNSG
GALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARSVLESIITTGTVTRGWIGVEPQDVTPEIAESFGLDQKSGAIVA
GVLKGGPADKAGIKPGDILVSVNGQDITDTTRLLNVIAQIKPGTDAKVHLVRKNKEMDLTVMIGKRPPPPKQPSDEGDDE
DGG

Sequences:

>Translated_403_residues
MLRRFWLFFAQAVTVLLALMFIIATLKPQWLQRQGQFGKQLAEPIVALREVAPGMGSGGSVQNSYADAAQKAMPAVVNVF
SSKDGSLPPDPRAKDPLFRYFFGDKNKKQQQEQPAANLGSGVIVSSEGYILTNQHVVDGADQIEIALADGRTTNAKVIGV
DPETDLAVLKVNMTNLPTITLGRMDQTRVGDVVLAIGNPFGVGQTVTMGIVSALGRNHLGINTFENFIQTDAPINPGNSG
GALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARSVLESIITTGTVTRGWIGVEPQDVTPEIAESFGLDQKSGAIVA
GVLKGGPADKAGIKPGDILVSVNGQDITDTTRLLNVIAQIKPGTDAKVHLVRKNKEMDLTVMIGKRPPPPKQPSDEGDDE
DGG
>Mature_403_residues
MLRRFWLFFAQAVTVLLALMFIIATLKPQWLQRQGQFGKQLAEPIVALREVAPGMGSGGSVQNSYADAAQKAMPAVVNVF
SSKDGSLPPDPRAKDPLFRYFFGDKNKKQQQEQPAANLGSGVIVSSEGYILTNQHVVDGADQIEIALADGRTTNAKVIGV
DPETDLAVLKVNMTNLPTITLGRMDQTRVGDVVLAIGNPFGVGQTVTMGIVSALGRNHLGINTFENFIQTDAPINPGNSG
GALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARSVLESIITTGTVTRGWIGVEPQDVTPEIAESFGLDQKSGAIVA
GVLKGGPADKAGIKPGDILVSVNGQDITDTTRLLNVIAQIKPGTDAKVHLVRKNKEMDLTVMIGKRPPPPKQPSDEGDDE
DGG

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=361, Percent_Identity=32.6869806094183, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI7019477, Length=327, Percent_Identity=33.9449541284404, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI24308541, Length=254, Percent_Identity=34.6456692913386, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI22129776, Length=320, Percent_Identity=32.1875, Blast_Score=131, Evalue=9e-31,
Organism=Escherichia coli, GI1789629, Length=326, Percent_Identity=45.7055214723926, Blast_Score=267, Evalue=8e-73,
Organism=Escherichia coli, GI1786356, Length=343, Percent_Identity=41.399416909621, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI1789630, Length=328, Percent_Identity=41.4634146341463, Blast_Score=226, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24646839, Length=308, Percent_Identity=33.1168831168831, Blast_Score=145, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 42513; Mature: 42513

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRFWLFFAQAVTVLLALMFIIATLKPQWLQRQGQFGKQLAEPIVALREVAPGMGSGGS
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VQNSYADAAQKAMPAVVNVFSSKDGSLPPDPRAKDPLFRYFFGDKNKKQQQEQPAANLGS
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHCCHHHCCC
GVIVSSEGYILTNQHVVDGADQIEIALADGRTTNAKVIGVDPETDLAVLKVNMTNLPTIT
CEEEECCCEEEECCEEECCCCEEEEEEECCCCCCCEEEEECCCCCEEEEEEECCCCCEEE
LGRMDQTRVGDVVLAIGNPFGVGQTVTMGIVSALGRNHLGINTFENFIQTDAPINPGNSG
ECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCC
GALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARSVLESIITTGTVTRGWIGVEPQD
CEEEEECCCEEEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCEECCCCCC
VTPEIAESFGLDQKSGAIVAGVLKGGPADKAGIKPGDILVSVNGQDITDTTRLLNVIAQI
CCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHC
KPGTDAKVHLVRKNKEMDLTVMIGKRPPPPKQPSDEGDDEDGG
CCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLRRFWLFFAQAVTVLLALMFIIATLKPQWLQRQGQFGKQLAEPIVALREVAPGMGSGGS
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VQNSYADAAQKAMPAVVNVFSSKDGSLPPDPRAKDPLFRYFFGDKNKKQQQEQPAANLGS
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHCCHHHCCC
GVIVSSEGYILTNQHVVDGADQIEIALADGRTTNAKVIGVDPETDLAVLKVNMTNLPTIT
CEEEECCCEEEECCEEECCCCEEEEEEECCCCCCCEEEEECCCCCEEEEEEECCCCCEEE
LGRMDQTRVGDVVLAIGNPFGVGQTVTMGIVSALGRNHLGINTFENFIQTDAPINPGNSG
ECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCC
GALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARSVLESIITTGTVTRGWIGVEPQD
CEEEEECCCEEEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCEECCCCCC
VTPEIAESFGLDQKSGAIVAGVLKGGPADKAGIKPGDILVSVNGQDITDTTRLLNVIAQI
CCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHC
KPGTDAKVHLVRKNKEMDLTVMIGKRPPPPKQPSDEGDDEDGG
CCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]