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The map label for this gene is murG

Identifier: 186477421

GI number: 186477421

Start: 3015095

End: 3016216

Strand: Reverse

Name: murG

Synonym: Bphy_2673

Alternate gene names: 186477421

Gene position: 3016216-3015095 (Counterclockwise)

Preceding gene: 186477422

Following gene: 186477420

Centisome position: 86.69

GC content: 66.58

Gene sequence:

>1122_bases
ATGACCCGCATGCAGCAGCGCACGCTGATGGTGATGGCGGGGGGCACCGGGGGACACGTATTCCCGGGGCTTGCCGTCGC
GCACCTGATGCAGGCGTGGGGCTGGCGCGTCGTGTGGCTCGGCAATCCCAATGGCATGGAAGCGACGCTCGTTCCCAAAC
ACGGCATTCCGATGGAGTACGTGCAGTTCGGCGGTCTGCGCGGAAAAGGCATGAAGACCAAGCTGATGCTGCCCGTCAAT
CTGCTGCGCGCGTGCATGCAGAGCCTGTCGGTGCTGCGTCGCGTGAAGCCCGACGTGGTGCTCGGCATGGGCGGCTACAT
CACCTTCCCGGCGGGCATGATGACGGCTTTGAGCGGCACGCCGCTCGTGCTGCATGAACAGAATTCGATCGCCGGTCTCG
CGAACAAGGTGCTGGCGAAACTCGCGAAGCGCGTGCTGGTCGCGTTTCCGAAAGCGCTGCCGCACGCCGAGTGGACGGGC
AACCCCATCCGCGAGGAACTTGCGCGCACGACGGCACCGCGGCAACGCTACGCAGCGCGTAGCGGTCCGCTGAATGTGCT
GGTCGTGGGCGGCAGTCTCGGTGCATCGGCGTTGAACGAAGTGGTCCCGCGCGCGCTCGCGAAGCTGGCGCCGCACGAGC
GGCCGCGCATCGTGCATCAGGCGGGCGCGAAGCATATCGACGCATTGCGGGCCAACTACGAAGCGGCAGGCATCGCGGCG
GGTGACGGCGCGCAGCTCGTGCCGTTCATCGACGACATGACGAGCGCCTATGCGAATGCGGATCTCGTGATTTGCCGCTC
GGGCGCGATGACGGTCGCCGAAATCGCGGCGGTGGGCGTGGCGGCATTCTTCGTGCCGTTCCCGTACGCCGTCGACGATC
ACCAGACAACCAACGCAGCGTTTCTCGCCGACAACGGCGCGGCGCTGCTCGTTCAACAACGCGATCTGTCGGCGGATGCG
CTCGCCGACTGGTTGCGCAGCCAGACGCGAGCCTCGCTCGCGGAAATGGCGGAGCGTTCGCGCTCGCTCGCGAAACCCGA
CGCCACCGAACAGGTCGCACAAATCTGCGCAACGGTGGCGGGCGTGACCCCGAGCCTGAGCCCGGAAGGAAAGCAGCAAT
GA

Upstream 100 bases:

>100_bases
TCAGCTACGGCGGCTCGGGCATCTTGCTGAACTGCATTGCCGTCGGCGTGCTGATGCGCGTCGACTACGAAAATCGAGTG
CTGATGCGTGGGGGGAAGGT

Downstream 100 bases:

>100_bases
AACATATCGTCAAACACATTCACTTCGTCGGGATCGGCGGCGCGGGCATGAGCGGCATCGCCGAAGTGCTCGTCAATCTC
GGCTATCAGGTGAGCGGATC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MTRMQQRTLMVMAGGTGGHVFPGLAVAHLMQAWGWRVVWLGNPNGMEATLVPKHGIPMEYVQFGGLRGKGMKTKLMLPVN
LLRACMQSLSVLRRVKPDVVLGMGGYITFPAGMMTALSGTPLVLHEQNSIAGLANKVLAKLAKRVLVAFPKALPHAEWTG
NPIREELARTTAPRQRYAARSGPLNVLVVGGSLGASALNEVVPRALAKLAPHERPRIVHQAGAKHIDALRANYEAAGIAA
GDGAQLVPFIDDMTSAYANADLVICRSGAMTVAEIAAVGVAAFFVPFPYAVDDHQTTNAAFLADNGAALLVQQRDLSADA
LADWLRSQTRASLAEMAERSRSLAKPDATEQVAQICATVAGVTPSLSPEGKQQ

Sequences:

>Translated_373_residues
MTRMQQRTLMVMAGGTGGHVFPGLAVAHLMQAWGWRVVWLGNPNGMEATLVPKHGIPMEYVQFGGLRGKGMKTKLMLPVN
LLRACMQSLSVLRRVKPDVVLGMGGYITFPAGMMTALSGTPLVLHEQNSIAGLANKVLAKLAKRVLVAFPKALPHAEWTG
NPIREELARTTAPRQRYAARSGPLNVLVVGGSLGASALNEVVPRALAKLAPHERPRIVHQAGAKHIDALRANYEAAGIAA
GDGAQLVPFIDDMTSAYANADLVICRSGAMTVAEIAAVGVAAFFVPFPYAVDDHQTTNAAFLADNGAALLVQQRDLSADA
LADWLRSQTRASLAEMAERSRSLAKPDATEQVAQICATVAGVTPSLSPEGKQQ
>Mature_372_residues
TRMQQRTLMVMAGGTGGHVFPGLAVAHLMQAWGWRVVWLGNPNGMEATLVPKHGIPMEYVQFGGLRGKGMKTKLMLPVNL
LRACMQSLSVLRRVKPDVVLGMGGYITFPAGMMTALSGTPLVLHEQNSIAGLANKVLAKLAKRVLVAFPKALPHAEWTGN
PIREELARTTAPRQRYAARSGPLNVLVVGGSLGASALNEVVPRALAKLAPHERPRIVHQAGAKHIDALRANYEAAGIAAG
DGAQLVPFIDDMTSAYANADLVICRSGAMTVAEIAAVGVAAFFVPFPYAVDDHQTTNAAFLADNGAALLVQQRDLSADAL
ADWLRSQTRASLAEMAERSRSLAKPDATEQVAQICATVAGVTPSLSPEGKQQ

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=356, Percent_Identity=50.2808988764045, Blast_Score=333, Evalue=2e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_BURP8 (B2JHG0)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001858891.1
- ProteinModelPortal:   B2JHG0
- SMR:   B2JHG0
- GeneID:   6244156
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_2673
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39576; Mature: 39444

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRMQQRTLMVMAGGTGGHVFPGLAVAHLMQAWGWRVVWLGNPNGMEATLVPKHGIPMEY
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCHHH
VQFGGLRGKGMKTKLMLPVNLLRACMQSLSVLRRVKPDVVLGMGGYITFPAGMMTALSGT
HHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCHHHHHHHCCC
PLVLHEQNSIAGLANKVLAKLAKRVLVAFPKALPHAEWTGNPIREELARTTAPRQRYAAR
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHC
SGPLNVLVVGGSLGASALNEVVPRALAKLAPHERPRIVHQAGAKHIDALRANYEAAGIAA
CCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCHHHHHHHHCCCCCCCEEC
GDGAQLVPFIDDMTSAYANADLVICRSGAMTVAEIAAVGVAAFFVPFPYAVDDHQTTNAA
CCCCEECHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
FLADNGAALLVQQRDLSADALADWLRSQTRASLAEMAERSRSLAKPDATEQVAQICATVA
EEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
GVTPSLSPEGKQQ
CCCCCCCCCCCCC
>Mature Secondary Structure 
TRMQQRTLMVMAGGTGGHVFPGLAVAHLMQAWGWRVVWLGNPNGMEATLVPKHGIPMEY
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCHHH
VQFGGLRGKGMKTKLMLPVNLLRACMQSLSVLRRVKPDVVLGMGGYITFPAGMMTALSGT
HHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCHHHHHHHCCC
PLVLHEQNSIAGLANKVLAKLAKRVLVAFPKALPHAEWTGNPIREELARTTAPRQRYAAR
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHC
SGPLNVLVVGGSLGASALNEVVPRALAKLAPHERPRIVHQAGAKHIDALRANYEAAGIAA
CCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCHHHHHHHHCCCCCCCEEC
GDGAQLVPFIDDMTSAYANADLVICRSGAMTVAEIAAVGVAAFFVPFPYAVDDHQTTNAA
CCCCEECHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
FLADNGAALLVQQRDLSADALADWLRSQTRASLAEMAERSRSLAKPDATEQVAQICATVA
EEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
GVTPSLSPEGKQQ
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA