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The map label for this gene is ftsW [H]

Identifier: 186477422

GI number: 186477422

Start: 3016213

End: 3017496

Strand: Reverse

Name: ftsW [H]

Synonym: Bphy_2674

Alternate gene names: 186477422

Gene position: 3017496-3016213 (Counterclockwise)

Preceding gene: 186477423

Following gene: 186477421

Centisome position: 86.73

GC content: 64.02

Gene sequence:

>1284_bases
ATGAGCTGGACGGAACGCTTCGGTTCGCAACTCGGCAAGCAACGCGGCTCGATCGCTGGGCAAACCGGCAGCGCGCCGGC
TTCCGAGCGCGCATCGCGCACGGGCGGGCTTTCGAGCGCCGTGAACGGCGTGCGCCCGCTGCGCTCGCGGATGCTCGACT
ACGACCACTCGCTGCTGTGGGTCGTCGTCGCGCTGCTGGGTCTCGGCATCGTGATGGTGTACTCGGCGTCGATCGCGATG
CCGGATTCGCCGAAGTACGCGTCATATCGCGATTACGCGTTCCTCGTGCGCCAGATCATTTTCGTCGTGATGGGTTCGAT
CGCGGGCGTGGTCGCGTTCCGCGTGCCCATTACGACGTGGGACAAGTACGCACCGAAGCTCTTCCTGATCGCGCTCGTCG
CGCTCGTAATCGTGCTGATTCCGCACGTCGGCAAGGGCGTGAATGGCGCGCGCCGCTGGATTCCCCTCGGCATCACGAAC
ATGCAGCCGTCGGAAATCATGAAGCTCGCCGTGACGATCTACGCGGCGAACTACACGGTGCGCAAGCAGGAATACATGCA
CAGCTTCGCGAAGGGCTTCCTGCCGATGGGCTTCGCCGTCGGCGTGGTCGGCATGCTGCTGCTGCTCGAACCCGATATGG
GCGCGTTCATGGTGATCGCGGCGATCGCGATGGGCGTGCTGTTCCTTGGCGGCGTCAACGGGAAGATCTTCGGCGGACTG
GTGGCGACGGCTATCGGTACGTTCACGCTGCTCGTGTGGGCGTCGCCGTGGCGCCGCGAGCGGATCTTCGCGTACCTCGA
TCCGTGGGACGACCGCTATGCACAGGGCAAGGCCTACCAGTTGACGCACTCGCTGATCGCCTTTGGCCGCGGCGAATGGT
TCGGCGTCGGTCTGGGCGGCAGCGTCGAGAAGCTCAACTATCTGCCCGAAGCGCACACCGACTTCATCCTTGCCGTGATC
GGTGAGGAACTCGGTTTCGTCGGGGTGCTCGTCGTGATCCTGATGTTCTACTGGATCGTGCGCCGTTCGTTCGAAATCGG
CCGTCAGGCGCTCGCGCTCGACCGCACGTTCGCGGGTCTCGTCGCGAAGGGCGTCGGCATCTGGTTCGGCGCGCAGACCT
TCATCAATATGGGCGTGAACCTCGGCCTGCTGCCGACCAAAGGTCTCACGCTGCCGCTTGTCAGCTACGGCGGCTCGGGC
ATCTTGCTGAACTGCATTGCCGTCGGCGTGCTGATGCGCGTCGACTACGAAAATCGAGTGCTGATGCGTGGGGGGAAGGT
ATGA

Upstream 100 bases:

>100_bases
CTGCATGCGCCAGCTTCGACATGTTCAAGGGTTACGCACATCGCGCCGCGGTTTTCCGCAGCACGGTCGAAGACATCGCT
GCCGGACGGGGGACGATGAT

Downstream 100 bases:

>100_bases
CCCGCATGCAGCAGCGCACGCTGATGGTGATGGCGGGGGGCACCGGGGGACACGTATTCCCGGGGCTTGCCGTCGCGCAC
CTGATGCAGGCGTGGGGCTG

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSWTERFGSQLGKQRGSIAGQTGSAPASERASRTGGLSSAVNGVRPLRSRMLDYDHSLLWVVVALLGLGIVMVYSASIAM
PDSPKYASYRDYAFLVRQIIFVVMGSIAGVVAFRVPITTWDKYAPKLFLIALVALVIVLIPHVGKGVNGARRWIPLGITN
MQPSEIMKLAVTIYAANYTVRKQEYMHSFAKGFLPMGFAVGVVGMLLLLEPDMGAFMVIAAIAMGVLFLGGVNGKIFGGL
VATAIGTFTLLVWASPWRRERIFAYLDPWDDRYAQGKAYQLTHSLIAFGRGEWFGVGLGGSVEKLNYLPEAHTDFILAVI
GEELGFVGVLVVILMFYWIVRRSFEIGRQALALDRTFAGLVAKGVGIWFGAQTFINMGVNLGLLPTKGLTLPLVSYGGSG
ILLNCIAVGVLMRVDYENRVLMRGGKV

Sequences:

>Translated_427_residues
MSWTERFGSQLGKQRGSIAGQTGSAPASERASRTGGLSSAVNGVRPLRSRMLDYDHSLLWVVVALLGLGIVMVYSASIAM
PDSPKYASYRDYAFLVRQIIFVVMGSIAGVVAFRVPITTWDKYAPKLFLIALVALVIVLIPHVGKGVNGARRWIPLGITN
MQPSEIMKLAVTIYAANYTVRKQEYMHSFAKGFLPMGFAVGVVGMLLLLEPDMGAFMVIAAIAMGVLFLGGVNGKIFGGL
VATAIGTFTLLVWASPWRRERIFAYLDPWDDRYAQGKAYQLTHSLIAFGRGEWFGVGLGGSVEKLNYLPEAHTDFILAVI
GEELGFVGVLVVILMFYWIVRRSFEIGRQALALDRTFAGLVAKGVGIWFGAQTFINMGVNLGLLPTKGLTLPLVSYGGSG
ILLNCIAVGVLMRVDYENRVLMRGGKV
>Mature_426_residues
SWTERFGSQLGKQRGSIAGQTGSAPASERASRTGGLSSAVNGVRPLRSRMLDYDHSLLWVVVALLGLGIVMVYSASIAMP
DSPKYASYRDYAFLVRQIIFVVMGSIAGVVAFRVPITTWDKYAPKLFLIALVALVIVLIPHVGKGVNGARRWIPLGITNM
QPSEIMKLAVTIYAANYTVRKQEYMHSFAKGFLPMGFAVGVVGMLLLLEPDMGAFMVIAAIAMGVLFLGGVNGKIFGGLV
ATAIGTFTLLVWASPWRRERIFAYLDPWDDRYAQGKAYQLTHSLIAFGRGEWFGVGLGGSVEKLNYLPEAHTDFILAVIG
EELGFVGVLVVILMFYWIVRRSFEIGRQALALDRTFAGLVAKGVGIWFGAQTFINMGVNLGLLPTKGLTLPLVSYGGSGI
LLNCIAVGVLMRVDYENRVLMRGGKV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=368, Percent_Identity=44.0217391304348, Blast_Score=304, Evalue=6e-84,
Organism=Escherichia coli, GI1786853, Length=344, Percent_Identity=32.8488372093023, Blast_Score=145, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 46416; Mature: 46284

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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ECCCCCC
>Mature Secondary Structure 
SWTERFGSQLGKQRGSIAGQTGSAPASERASRTGGLSSAVNGVRPLRSRMLDYDHSLLW
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHH
VVVALLGLGIVMVYSASIAMPDSPKYASYRDYAFLVRQIIFVVMGSIAGVVAFRVPITTW
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCH
DKYAPKLFLIALVALVIVLIPHVGKGVNGARRWIPLGITNMQPSEIMKLAVTIYAANYTV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHEECCCCH
RKQEYMHSFAKGFLPMGFAVGVVGMLLLLEPDMGAFMVIAAIAMGVLFLGGVNGKIFGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
VATAIGTFTLLVWASPWRRERIFAYLDPWDDRYAQGKAYQLTHSLIAFGRGEWFGVGLGG
HHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHCCCHHHHHHHHHHHCCCCEEEECCCC
SVEKLNYLPEAHTDFILAVIGEELGFVGVLVVILMFYWIVRRSFEIGRQALALDRTFAGL
CHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAKGVGIWFGAQTFINMGVNLGLLPTKGLTLPLVSYGGSGILLNCIAVGVLMRVDYENRV
HHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEHHHCCCCHHHHHHHHHHHHHHCCCCCEE
LMRGGKV
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]