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The map label for this gene is murC [H]

Identifier: 186477420

GI number: 186477420

Start: 3013704

End: 3015098

Strand: Reverse

Name: murC [H]

Synonym: Bphy_2672

Alternate gene names: 186477420

Gene position: 3015098-3013704 (Counterclockwise)

Preceding gene: 186477421

Following gene: 186477419

Centisome position: 86.66

GC content: 64.37

Gene sequence:

>1395_bases
ATGAAACATATCGTCAAACACATTCACTTCGTCGGGATCGGCGGCGCGGGCATGAGCGGCATCGCCGAAGTGCTCGTCAA
TCTCGGCTATCAGGTGAGCGGATCGGACCTGTCGCGCAACGCGGTGACGGAGCGCCTCGCCGCGCTCGGTGCGCGCATCG
CGATCGGCCACGACGCAGCGAACATCGAAGGCGCGAACGCCGTCGTCGTCTCCACGGCCGTGCGCAGCGACAACCCTGAA
GTGCTGGCCGCGCGCCATCGCCGCATTCCTATCGTGCCGCGCGCCGTGATGCTTGCGGAACTGATGCGCCTGAAGCAGGG
CATCGCGATCGCGGGCACGCACGGCAAGACCACGACCACCTCGCTGGTGGCGAGCGTGCTGGCGGCGGGCGGTCTCGATC
CGACCTTCGTGATCGGCGGCCGGCTGATCAGCGCCGGCGCGAATGCGCGTCTCGGCACGGGCGATTTCATCGTCGCCGAA
GCGGACGAATCCGATGCGTCGTTCCTGAACCTGTTTCCGGTGATCGAAGTCATCACGAACATCGACGCCGATCACATGGA
CACCTACGGCCACGACTTCGCGCGGCTGAAGCAGGCGTTCATTGAATTTACGCATCGTCTGCCGTTTTATGGCATTGCGG
TGCTGTGCGTCGACGATCCGAACGTGAAGGAGATTCTGCCGTTCGTGTCGAAGCCGATCATCCGCTACGGCTTCGCGCCC
GATGCGCAGGTGCGCGCGGTGAACGTCGAAGCGCGCGAAGGCAAGATGCATTTCACGGCGATGCGCGAGGATGCGCCGCC
CATCGACATCGTGTTGAACCTGCCGGGTCTGCACAACGTGCAGAACGCGCTCGCCGCGATTGCGATTGCGACTGAACTTG
AGGTGAAAGATGCCGATATCCAGCGAGCGCTCGCGGATTTCAACGGCGTCGGCCGGCGTTTTCAGCGTTACGGGGAAGTG
ACCGTGACGAGCGGCGGCGCGTACACGCTCGTCGACGACTACGGCCATCACCCGGTCGAAATGGCGGCGACGATTGCGGC
GGCGCGCGGTGCATTTCCGGACAAGCGTCTCGTGCTCGCGTTCCAGCCTCACCGGTTCACGCGCACGCGCGACTGCTTCG
AAGATTTCGTGAAGGTGCTGTCGACGGTCGACGCGCTCGTGCTGACGGAAGTCTATTCGGCGGGCGAAGCGCCCATCGTC
GCGGCGGACGGCCGTTCGCTCACGCGCGCGATCCGCGTGGCGGGCAAGGTGGAGCCGGTGTTTGTCGACACAGTGGATGA
AGTGCCGGATGCGCTCGGTGCAATCGTGCGCGACGGCGATGTGGTGATCACGATGGGTGCGGGTTCGATCGGGAGTGTGC
CGGGTCGGCTCGCAGGAAACGAAGGTGTGAAATGA

Upstream 100 bases:

>100_bases
CGCGCTCGCTCGCGAAACCCGACGCCACCGAACAGGTCGCACAAATCTGCGCAACGGTGGCGGGCGTGACCCCGAGCCTG
AGCCCGGAAGGAAAGCAGCA

Downstream 100 bases:

>100_bases
GCGGTATCGATCCTAAATCTTTCGGCAAGGTTGCCGTGCTGCTCGGCGGTGCGTCCGCCGAGCGCGAAGTGTCGCTGAAC
TCCGGCCGTCTCGTGCTGCA

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLSRNAVTERLAALGARIAIGHDAANIEGANAVVVSTAVRSDNPE
VLAARHRRIPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAE
ADESDASFLNLFPVIEVITNIDADHMDTYGHDFARLKQAFIEFTHRLPFYGIAVLCVDDPNVKEILPFVSKPIIRYGFAP
DAQVRAVNVEAREGKMHFTAMREDAPPIDIVLNLPGLHNVQNALAAIAIATELEVKDADIQRALADFNGVGRRFQRYGEV
TVTSGGAYTLVDDYGHHPVEMAATIAAARGAFPDKRLVLAFQPHRFTRTRDCFEDFVKVLSTVDALVLTEVYSAGEAPIV
AADGRSLTRAIRVAGKVEPVFVDTVDEVPDALGAIVRDGDVVITMGAGSIGSVPGRLAGNEGVK

Sequences:

>Translated_464_residues
MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLSRNAVTERLAALGARIAIGHDAANIEGANAVVVSTAVRSDNPE
VLAARHRRIPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAE
ADESDASFLNLFPVIEVITNIDADHMDTYGHDFARLKQAFIEFTHRLPFYGIAVLCVDDPNVKEILPFVSKPIIRYGFAP
DAQVRAVNVEAREGKMHFTAMREDAPPIDIVLNLPGLHNVQNALAAIAIATELEVKDADIQRALADFNGVGRRFQRYGEV
TVTSGGAYTLVDDYGHHPVEMAATIAAARGAFPDKRLVLAFQPHRFTRTRDCFEDFVKVLSTVDALVLTEVYSAGEAPIV
AADGRSLTRAIRVAGKVEPVFVDTVDEVPDALGAIVRDGDVVITMGAGSIGSVPGRLAGNEGVK
>Mature_464_residues
MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLSRNAVTERLAALGARIAIGHDAANIEGANAVVVSTAVRSDNPE
VLAARHRRIPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAE
ADESDASFLNLFPVIEVITNIDADHMDTYGHDFARLKQAFIEFTHRLPFYGIAVLCVDDPNVKEILPFVSKPIIRYGFAP
DAQVRAVNVEAREGKMHFTAMREDAPPIDIVLNLPGLHNVQNALAAIAIATELEVKDADIQRALADFNGVGRRFQRYGEV
TVTSGGAYTLVDDYGHHPVEMAATIAAARGAFPDKRLVLAFQPHRFTRTRDCFEDFVKVLSTVDALVLTEVYSAGEAPIV
AADGRSLTRAIRVAGKVEPVFVDTVDEVPDALGAIVRDGDVVITMGAGSIGSVPGRLAGNEGVK

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=458, Percent_Identity=55.4585152838428, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1790680, Length=466, Percent_Identity=27.8969957081545, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 49246; Mature: 49246

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLSRNAVTERLAALGARIAIGHDAA
CCCHHCEEEEEEECCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCEEEECCCCC
NIEGANAVVVSTAVRSDNPEVLAARHRRIPIVPRAVMLAELMRLKQGIAIAGTHGKTTTT
CCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHH
SLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAEADESDASFLNLFPVIEVITN
HHHHHHHHHCCCCCEEEECCEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC
IDADHMDTYGHDFARLKQAFIEFTHRLPFYGIAVLCVDDPNVKEILPFVSKPIIRYGFAP
CCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHCCHHHCCCCC
DAQVRAVNVEAREGKMHFTAMREDAPPIDIVLNLPGLHNVQNALAAIAIATELEVKDADI
CCEEEEEEEEECCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHEECEECHHHH
QRALADFNGVGRRFQRYGEVTVTSGGAYTLVDDYGHHPVEMAATIAAARGAFPDKRLVLA
HHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEE
FQPHRFTRTRDCFEDFVKVLSTVDALVLTEVYSAGEAPIVAADGRSLTRAIRVAGKVEPV
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCEE
FVDTVDEVPDALGAIVRDGDVVITMGAGSIGSVPGRLAGNEGVK
EECCHHHHHHHHHHHEECCCEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLSRNAVTERLAALGARIAIGHDAA
CCCHHCEEEEEEECCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCEEEECCCCC
NIEGANAVVVSTAVRSDNPEVLAARHRRIPIVPRAVMLAELMRLKQGIAIAGTHGKTTTT
CCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHH
SLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAEADESDASFLNLFPVIEVITN
HHHHHHHHHCCCCCEEEECCEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC
IDADHMDTYGHDFARLKQAFIEFTHRLPFYGIAVLCVDDPNVKEILPFVSKPIIRYGFAP
CCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHCCHHHCCCCC
DAQVRAVNVEAREGKMHFTAMREDAPPIDIVLNLPGLHNVQNALAAIAIATELEVKDADI
CCEEEEEEEEECCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHEECEECHHHH
QRALADFNGVGRRFQRYGEVTVTSGGAYTLVDDYGHHPVEMAATIAAARGAFPDKRLVLA
HHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEE
FQPHRFTRTRDCFEDFVKVLSTVDALVLTEVYSAGEAPIVAADGRSLTRAIRVAGKVEPV
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCEE
FVDTVDEVPDALGAIVRDGDVVITMGAGSIGSVPGRLAGNEGVK
EECCHHHHHHHHHHHEECCCEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA