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The map label for this gene is prmA

Identifier: 186477379

GI number: 186477379

Start: 2969957

End: 2970859

Strand: Direct

Name: prmA

Synonym: Bphy_2631

Alternate gene names: 186477379

Gene position: 2969957-2970859 (Clockwise)

Preceding gene: 186477378

Following gene: 186477380

Centisome position: 85.36

GC content: 64.89

Gene sequence:

>903_bases
ATGAGCTACCGGGAACTGGTCGTCGAACTCGCACGCGAGCACGCGGAAGCGTTGTCGGATGCGCTGCTCGAACTGGGCGC
GCTGTCGGTGTCCGTCGAGGACGCGGACGCCGACACGCCCGACGAGCAGCCGCTGTTCGGCGAACCCGGGCTCACGCCGG
AGCGCACCGCGTGGACCCACTCACGCGTGATCGCGCTGCTGGCGCCGGAACACGAGCCGGCCGTGCTGCTCGCGGCCGCC
GCGAATGAACTCGGTCTCGCTGACACACCGTCGTTCAGCGTGCGCGCGGTCGAAGAACAGGACTGGGTGCGCCTCACGCA
ATCCCAGTTCGATCCGATTCCGATCGGAGAACGCATCTGGGTCGTGCCATCGTGGCACGATGCGCCCGATCCGGACGCGC
TCGTGCTCGAACTCGATCCGGGCCTCGCGTTCGGCACGGGCAGCCATCCCACGACAAGGCTGTGCATGGAATGGCTCGAA
CAGTCCGTGCAAAAAGATCAGTCTGTACTCGACTACGGTTGTGGCTCGGGCATTCTCGCGATTCTCGCGAAGAAGTGCGG
CGCAAATCCCGTCTTCGGCATCGACATTGATCCGCAAGCCGTCGAATCCGCCCGCCACAACAGCGAGCGCAATCGCGCCG
AGATCACCTACGGTCTGCCCGCCGACTGCCCTGCCGGCGAGTTCGACATCGTCGTCGCGAACATCCTGTCGAATCCGCTG
AAGCTGATGGCGTCGATGCTGTCGTCGAAGGTGAAGCCGGGCGGACGCATTGCGCTGTCAGGCATACTCGCGCGCCAGGC
GGAAGAAGTGGCGAGCGTTTACCGGCAGTGGATCGACATCGCCGTGTGGCGCGAACACGAAGGCTGGGTGTGCCTTGCAG
GTACGCGTCGCGAAAGCAATTAG

Upstream 100 bases:

>100_bases
GATGCTCGACGCGAAGTTCGTCGAGGGCGGCACGAGCATCCATTACCTCGAAAACCGGCTGGCCGCGAAGCTGCAAGCCG
CACCGGAAGAAGCGTAAGCA

Downstream 100 bases:

>100_bases
AATAAGGCATATTTGCTTGCTTCCGGCCCCATTCGGCACCCTGGCCGCCAACCGGTCTTTCGGCTCGATATGCTTCTAGC
GACACGCTGTCCCTTCTGCG

Product: 50S ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSYRELVVELAREHAEALSDALLELGALSVSVEDADADTPDEQPLFGEPGLTPERTAWTHSRVIALLAPEHEPAVLLAAA
ANELGLADTPSFSVRAVEEQDWVRLTQSQFDPIPIGERIWVVPSWHDAPDPDALVLELDPGLAFGTGSHPTTRLCMEWLE
QSVQKDQSVLDYGCGSGILAILAKKCGANPVFGIDIDPQAVESARHNSERNRAEITYGLPADCPAGEFDIVVANILSNPL
KLMASMLSSKVKPGGRIALSGILARQAEEVASVYRQWIDIAVWREHEGWVCLAGTRRESN

Sequences:

>Translated_300_residues
MSYRELVVELAREHAEALSDALLELGALSVSVEDADADTPDEQPLFGEPGLTPERTAWTHSRVIALLAPEHEPAVLLAAA
ANELGLADTPSFSVRAVEEQDWVRLTQSQFDPIPIGERIWVVPSWHDAPDPDALVLELDPGLAFGTGSHPTTRLCMEWLE
QSVQKDQSVLDYGCGSGILAILAKKCGANPVFGIDIDPQAVESARHNSERNRAEITYGLPADCPAGEFDIVVANILSNPL
KLMASMLSSKVKPGGRIALSGILARQAEEVASVYRQWIDIAVWREHEGWVCLAGTRRESN
>Mature_299_residues
SYRELVVELAREHAEALSDALLELGALSVSVEDADADTPDEQPLFGEPGLTPERTAWTHSRVIALLAPEHEPAVLLAAAA
NELGLADTPSFSVRAVEEQDWVRLTQSQFDPIPIGERIWVVPSWHDAPDPDALVLELDPGLAFGTGSHPTTRLCMEWLEQ
SVQKDQSVLDYGCGSGILAILAKKCGANPVFGIDIDPQAVESARHNSERNRAEITYGLPADCPAGEFDIVVANILSNPLK
LMASMLSSKVKPGGRIALSGILARQAEEVASVYRQWIDIAVWREHEGWVCLAGTRRESN

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=300, Percent_Identity=41.6666666666667, Blast_Score=189, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_BURP8 (B2JH19)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001858849.1
- ProteinModelPortal:   B2JH19
- SMR:   B2JH19
- GeneID:   6244114
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_2631
- HOGENOM:   HBG584653
- OMA:   EREEWCR
- ProtClustDB:   PRK00517
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32603; Mature: 32472

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRELVVELAREHAEALSDALLELGALSVSVEDADADTPDEQPLFGEPGLTPERTAWTH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHH
SRVIALLAPEHEPAVLLAAAANELGLADTPSFSVRAVEEQDWVRLTQSQFDPIPIGERIW
HEEEEEECCCCCCEEEEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCCCEEE
VVPSWHDAPDPDALVLELDPGLAFGTGSHPTTRLCMEWLEQSVQKDQSVLDYGCGSGILA
EEECCCCCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ILAKKCGANPVFGIDIDPQAVESARHNSERNRAEITYGLPADCPAGEFDIVVANILSNPL
HHHHHHCCCCEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCHH
KLMASMLSSKVKPGGRIALSGILARQAEEVASVYRQWIDIAVWREHEGWVCLAGTRRESN
HHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCCCCCC
>Mature Secondary Structure 
SYRELVVELAREHAEALSDALLELGALSVSVEDADADTPDEQPLFGEPGLTPERTAWTH
CHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHH
SRVIALLAPEHEPAVLLAAAANELGLADTPSFSVRAVEEQDWVRLTQSQFDPIPIGERIW
HEEEEEECCCCCCEEEEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCCCEEE
VVPSWHDAPDPDALVLELDPGLAFGTGSHPTTRLCMEWLEQSVQKDQSVLDYGCGSGILA
EEECCCCCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ILAKKCGANPVFGIDIDPQAVESARHNSERNRAEITYGLPADCPAGEFDIVVANILSNPL
HHHHHHCCCCEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCHH
KLMASMLSSKVKPGGRIALSGILARQAEEVASVYRQWIDIAVWREHEGWVCLAGTRRESN
HHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA