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The map label for this gene is qseD [H]

Identifier: 186477323

GI number: 186477323

Start: 2895391

End: 2896347

Strand: Reverse

Name: qseD [H]

Synonym: Bphy_2575

Alternate gene names: 186477323

Gene position: 2896347-2895391 (Counterclockwise)

Preceding gene: 186477325

Following gene: 186477322

Centisome position: 83.25

GC content: 65.2

Gene sequence:

>957_bases
ATGGAACTGAAATGGCTCGAAGATTTCGTGTCGCTGGCGGAAACGCGCAGCTTCAGCCGCTCGGCGGAACTGCGGCACGT
GACGCAGCCCGCTTTCTCGCGCCGCATCCAGGCGCTCGAAGCGTGGCTCGGTACGGAACTGATCGATCGTTCGGTTTACC
CGACGCGTCTCACCGCAGCGGGCCAGGTTTTCTATGAGCAGGCGCTCGCCATGCTCTCGCAGTTCCATGAAGCCCGCACG
CTGCTGCGCGGCCACACGGCCACGCCCGCCGCGACGATCGAATTCGCCGTGCCGCATACGCTGTCACTCACGTATTTCCC
GCGCTGGCTGCAGCGCATCGAGGGGCAGATCGGCTCGATTCACACGCGGCTTCGCGCGCTGAACGTGCACGACGCCGTGC
TGTCGCTGGTCGAAGGCGGCTGCGATCTGGTGATGGGCTATCACCATCCGAGTCACCCCGTCGCCCTCGATCCCGCGCGC
TACGACATGCTGACCCTTGGCATCGAAACGATCAGCCCGTTCTCCGCGCCTGGCAAGGGCGGACGCGCGCGCTACACGCT
GCCCGGCACGCCCGAAGCGCCGACGCCGTATCTGTCCTATACGCCGAATGCGTATCTGGGCCGCATGACGGAAGTGATCT
TCGCGACGGCGCCCGGACGCCTGTATCTCGATCGCGTGTATGAAACGGACATGGCCGAAGGACTGAAGGCGATGGCGCTT
GCCGGACACGGCGTCGCGTTCCTGCCGCACAGCGCCGTCGAAGACGCCGTCGCCGAAGGCAAGCTGATTCGCCTCGATCG
TGCAACACGCGGCATCGCGCAAGGGCAGTTCACGCTGACGATGGAAATTCGCCTCTATCGCGACAAGCTCGCCGTGCAAT
CGGACGACGCGCGCCACCAACTCGTGCGCGCGCTGTGGGATGTCGTGAGCGCCGAGCTCGCGCAAGCATCAAGGTAG

Upstream 100 bases:

>100_bases
GACATCGGCCCTGCCGCGTGCGCCGGCATCGATGCGCGTGCGCATCCGCGGCGCCGCTAGAATGCAGGCTTTCCGTTACA
GCTGGGAGCGCTAGGTCCGT

Downstream 100 bases:

>100_bases
GCACCAGTGCATTGCCCGCCTCGTCAATAACGGCCTCGCGACATGCATTTGCGCTTTCCGCAGGGTTATGCAAGAAAAAC
ATAACCGGATGACCAAACGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MELKWLEDFVSLAETRSFSRSAELRHVTQPAFSRRIQALEAWLGTELIDRSVYPTRLTAAGQVFYEQALAMLSQFHEART
LLRGHTATPAATIEFAVPHTLSLTYFPRWLQRIEGQIGSIHTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPAR
YDMLTLGIETISPFSAPGKGGRARYTLPGTPEAPTPYLSYTPNAYLGRMTEVIFATAPGRLYLDRVYETDMAEGLKAMAL
AGHGVAFLPHSAVEDAVAEGKLIRLDRATRGIAQGQFTLTMEIRLYRDKLAVQSDDARHQLVRALWDVVSAELAQASR

Sequences:

>Translated_318_residues
MELKWLEDFVSLAETRSFSRSAELRHVTQPAFSRRIQALEAWLGTELIDRSVYPTRLTAAGQVFYEQALAMLSQFHEART
LLRGHTATPAATIEFAVPHTLSLTYFPRWLQRIEGQIGSIHTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPAR
YDMLTLGIETISPFSAPGKGGRARYTLPGTPEAPTPYLSYTPNAYLGRMTEVIFATAPGRLYLDRVYETDMAEGLKAMAL
AGHGVAFLPHSAVEDAVAEGKLIRLDRATRGIAQGQFTLTMEIRLYRDKLAVQSDDARHQLVRALWDVVSAELAQASR
>Mature_318_residues
MELKWLEDFVSLAETRSFSRSAELRHVTQPAFSRRIQALEAWLGTELIDRSVYPTRLTAAGQVFYEQALAMLSQFHEART
LLRGHTATPAATIEFAVPHTLSLTYFPRWLQRIEGQIGSIHTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPAR
YDMLTLGIETISPFSAPGKGGRARYTLPGTPEAPTPYLSYTPNAYLGRMTEVIFATAPGRLYLDRVYETDMAEGLKAMAL
AGHGVAFLPHSAVEDAVAEGKLIRLDRATRGIAQGQFTLTMEIRLYRDKLAVQSDDARHQLVRALWDVVSAELAQASR

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=286, Percent_Identity=33.5664335664336, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI145693193, Length=266, Percent_Identity=25.187969924812, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788887, Length=79, Percent_Identity=41.7721518987342, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787879, Length=289, Percent_Identity=27.3356401384083, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35297; Mature: 35297

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKWLEDFVSLAETRSFSRSAELRHVTQPAFSRRIQALEAWLGTELIDRSVYPTRLTAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
GQVFYEQALAMLSQFHEARTLLRGHTATPAATIEFAVPHTLSLTYFPRWLQRIEGQIGSI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEHHHHHHHHHHHCCHHHHH
HTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPARYDMLTLGIETISPFSAPGKG
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEECCCHHHHHEECHHHCCCCCCCCCC
GRARYTLPGTPEAPTPYLSYTPNAYLGRMTEVIFATAPGRLYLDRVYETDMAEGLKAMAL
CCEEEECCCCCCCCCCCEECCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHH
AGHGVAFLPHSAVEDAVAEGKLIRLDRATRGIAQGQFTLTMEIRLYRDKLAVQSDDARHQ
CCCCEEECCCHHHHHHHHCCCEEEECHHHCCCCCCEEEEEEEEEEEHHHHHCCCCHHHHH
LVRALWDVVSAELAQASR
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELKWLEDFVSLAETRSFSRSAELRHVTQPAFSRRIQALEAWLGTELIDRSVYPTRLTAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
GQVFYEQALAMLSQFHEARTLLRGHTATPAATIEFAVPHTLSLTYFPRWLQRIEGQIGSI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEHHHHHHHHHHHCCHHHHH
HTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPARYDMLTLGIETISPFSAPGKG
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEECCCHHHHHEECHHHCCCCCCCCCC
GRARYTLPGTPEAPTPYLSYTPNAYLGRMTEVIFATAPGRLYLDRVYETDMAEGLKAMAL
CCEEEECCCCCCCCCCCEECCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHH
AGHGVAFLPHSAVEDAVAEGKLIRLDRATRGIAQGQFTLTMEIRLYRDKLAVQSDDARHQ
CCCCEEECCCHHHHHHHHCCCEEEECHHHCCCCCCEEEEEEEEEEEHHHHHCCCCHHHHH
LVRALWDVVSAELAQASR
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]