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The map label for this gene is ahpC [C]

Identifier: 186477188

GI number: 186477188

Start: 2742438

End: 2743076

Strand: Reverse

Name: ahpC [C]

Synonym: Bphy_2439

Alternate gene names: 186477188

Gene position: 2743076-2742438 (Counterclockwise)

Preceding gene: 186477192

Following gene: 186477186

Centisome position: 78.84

GC content: 58.53

Gene sequence:

>639_bases
ATGAGTCTACGTCTTGGCGACGTCGCACCCGATTTCGAACAGGAGTCGAGCATTGGCCGCATCAGTTTCCACGAATGGTT
GGGTGACAGCTGGGGCGTTCTTTTTTCGCACCCGGCCGACTTCACGCCTGTCTGCACGACGGAACTGGGCCTGACCGCGA
AGCTTGCGAACGAATTCGAGAAGCGCAACGTGAAGACGATCGCGCTGTCAGTCGACAGCAAGGATTCGCATAACGAGTGG
ATCAAGGACATCAACGAGACGCAGGCCGCGAGCGTTGGCTTTCCGATTCTCGCCGACGGCGACCGCAAGGTCTCGCAACT
GTACGACATGATTCACCCGAACGCGAACGAAACGCTGACCGTTCGTTCGCTCTTCATCATCGACCCGAAGAAAAAGGTGC
GTCTGATCATTACGTACCCGGCCAGCACGGGTCGCAACTTCGACGAAGTGCTGCGCGTGATCGACTCGCTGCAGCTGACG
GACAACTATCAGGTGGCAACGCCCGGTAACTGGAAGCACGGCGACGACGTCGTGATCGTGCCGTCGCTCAAGGACGAAGA
AGAGATCAGGCGCAAGTTCCCGAAGGGCTACAAGGCGCTGCGCCCGTATCTGCGACTGACGCCGCAGCCGAACAAGTAA

Upstream 100 bases:

>100_bases
TTCGTTAGAAGCGCACGCTGCCGTCCCGTATGCTCTAATTTGTACCCCTCGACCGGGCCTGGGCCTGGCGAAACATTCGA
ACACTTCAAGGAGCTGCACT

Downstream 100 bases:

>100_bases
GCATCGGCCTCTGACGAGGCAAAAAGAAAAGCCCGCGTTCGTTGAGAACGCGGGCTTTTAAATAGGCGCCGTTTGAGGCG
CACTGAGGTGTCAGAAGAAC

Product: peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSLRLGDVAPDFEQESSIGRISFHEWLGDSWGVLFSHPADFTPVCTTELGLTAKLANEFEKRNVKTIALSVDSKDSHNEW
IKDINETQAASVGFPILADGDRKVSQLYDMIHPNANETLTVRSLFIIDPKKKVRLIITYPASTGRNFDEVLRVIDSLQLT
DNYQVATPGNWKHGDDVVIVPSLKDEEEIRRKFPKGYKALRPYLRLTPQPNK

Sequences:

>Translated_212_residues
MSLRLGDVAPDFEQESSIGRISFHEWLGDSWGVLFSHPADFTPVCTTELGLTAKLANEFEKRNVKTIALSVDSKDSHNEW
IKDINETQAASVGFPILADGDRKVSQLYDMIHPNANETLTVRSLFIIDPKKKVRLIITYPASTGRNFDEVLRVIDSLQLT
DNYQVATPGNWKHGDDVVIVPSLKDEEEIRRKFPKGYKALRPYLRLTPQPNK
>Mature_211_residues
SLRLGDVAPDFEQESSIGRISFHEWLGDSWGVLFSHPADFTPVCTTELGLTAKLANEFEKRNVKTIALSVDSKDSHNEWI
KDINETQAASVGFPILADGDRKVSQLYDMIHPNANETLTVRSLFIIDPKKKVRLIITYPASTGRNFDEVLRVIDSLQLTD
NYQVATPGNWKHGDDVVIVPSLKDEEEIRRKFPKGYKALRPYLRLTPQPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=222, Percent_Identity=53.1531531531532, Blast_Score=228, Evalue=2e-60,
Organism=Homo sapiens, GI32189392, Length=194, Percent_Identity=33.5051546391753, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI4505591, Length=195, Percent_Identity=32.3076923076923, Blast_Score=100, Evalue=7e-22,
Organism=Homo sapiens, GI32455266, Length=195, Percent_Identity=32.3076923076923, Blast_Score=100, Evalue=7e-22,
Organism=Homo sapiens, GI32455264, Length=195, Percent_Identity=32.3076923076923, Blast_Score=100, Evalue=7e-22,
Organism=Homo sapiens, GI5453549, Length=148, Percent_Identity=34.4594594594595, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI32483377, Length=161, Percent_Identity=32.2981366459627, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI5802974, Length=161, Percent_Identity=32.2981366459627, Blast_Score=84, Evalue=8e-17,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=31.1688311688312, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25153706, Length=198, Percent_Identity=43.9393939393939, Blast_Score=171, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI193204376, Length=193, Percent_Identity=31.6062176165803, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32565831, Length=193, Percent_Identity=31.6062176165803, Blast_Score=98, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17554494, Length=166, Percent_Identity=32.5301204819277, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=53.7735849056604, Blast_Score=230, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6323613, Length=193, Percent_Identity=30.5699481865285, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320661, Length=185, Percent_Identity=31.8918918918919, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24581278, Length=219, Percent_Identity=49.3150684931507, Blast_Score=218, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24652434, Length=203, Percent_Identity=50.7389162561576, Blast_Score=193, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24652436, Length=203, Percent_Identity=50.7389162561576, Blast_Score=192, Evalue=1e-49,
Organism=Drosophila melanogaster, GI17975518, Length=203, Percent_Identity=50.7389162561576, Blast_Score=192, Evalue=1e-49,
Organism=Drosophila melanogaster, GI17157991, Length=183, Percent_Identity=33.879781420765, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24641739, Length=183, Percent_Identity=33.879781420765, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17738015, Length=200, Percent_Identity=31.5, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24656348, Length=192, Percent_Identity=33.8541666666667, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17864676, Length=192, Percent_Identity=33.8541666666667, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21357347, Length=192, Percent_Identity=29.1666666666667, Blast_Score=90, Evalue=9e-19,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23994; Mature: 23863

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRLGDVAPDFEQESSIGRISFHEWLGDSWGVLFSHPADFTPVCTTELGLTAKLANEFE
CCCCCCCCCCCCCCCCCCCCEEHHHHCCCCCCEEEECCCCCCCEEECCCCHHHHHHHHHH
KRNVKTIALSVDSKDSHNEWIKDINETQAASVGFPILADGDRKVSQLYDMIHPNANETLT
HCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHCCCCCCEEE
VRSLFIIDPKKKVRLIITYPASTGRNFDEVLRVIDSLQLTDNYQVATPGNWKHGDDVVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEE
PSLKDEEEIRRKFPKGYKALRPYLRLTPQPNK
CCCCCHHHHHHHCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SLRLGDVAPDFEQESSIGRISFHEWLGDSWGVLFSHPADFTPVCTTELGLTAKLANEFE
CCCCCCCCCCCCCCCCCCCEEHHHHCCCCCCEEEECCCCCCCEEECCCCHHHHHHHHHH
KRNVKTIALSVDSKDSHNEWIKDINETQAASVGFPILADGDRKVSQLYDMIHPNANETLT
HCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHCCCCCCEEE
VRSLFIIDPKKKVRLIITYPASTGRNFDEVLRVIDSLQLTDNYQVATPGNWKHGDDVVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEE
PSLKDEEEIRRKFPKGYKALRPYLRLTPQPNK
CCCCCHHHHHHHCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]