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The map label for this gene is pcaR [H]

Identifier: 186477186

GI number: 186477186

Start: 2740215

End: 2741039

Strand: Reverse

Name: pcaR [H]

Synonym: Bphy_2437

Alternate gene names: 186477186

Gene position: 2741039-2740215 (Counterclockwise)

Preceding gene: 186477188

Following gene: 186477184

Centisome position: 78.78

GC content: 66.42

Gene sequence:

>825_bases
ATGTCGAAACCTGCATCCACAACATCCCCAAGTCCCGTGACGTCCTTGTCGACGCGGACTTCCGATCCCGTCGACGAGCG
CAAGTTCGTCGTCGCGCTGGCTCGCGGACTCGATCTGCTACGCGCATTCCGGCCGGGCGAAACGCTGCTCGGCAATCGCG
ACTTCGTCGAGCGCACGGGCTTGCCGAAGGCGACGGTGAACCGGCTCGCGTACACGTTGACGGTGCTCGGCTATCTGCGC
TTCGACGAGGCGCTCGGCAAATATGCACTGGACGCTGGCGTGCTATCGCTGGGCTTTGCGCTGCTGTCGGGCACCGACAC
GCTCGAACTCGCGCGCCCGCACATGCGCAATTTCGCGCGGGAGGTCGGCGCGGCCGTGTCGCTCGGGTGTCGCGACGGAC
TGGACATGATTTATCTGGAGACGATCCGCAGTGAGACGGCGCTGACGCTCGGTCTCGCATCCGGCTCGAAGCTGTCGATG
CTGACGAGTTCGATGGGCCGTGCCTATCTCGCCGTACAGCCCGCCGACACACGCGCCGCGCTGCTCGACGAACTACGGCG
TGCGGCGGGCGACGAAGGCGCGCTGCTGGTCGCGCAGGCGCAAAGAGAGATCGACAGGTACGCGAGCGAGGGATGCTGCT
ACTCGTTTCGCGACTGGCACGACGATGTGAACGCCGTGGCCGTCCCGTTCAGCGATCCGCGCGACGGCAGGCTGCTGGTG
CTGAGCTGTAGCGGGCCGGCGTCGTCGATGGGGGAGAGCGTGTTTCGGGAACGGGTCGCACCGCGACTGAAGGCACTCGC
GCGCCGTCTGGGCGACAGTCCTTGA

Upstream 100 bases:

>100_bases
ACGAGAGGGCGCCTTCGCGCGTATCCTCGTCCGAATGCTTGACTTGAGTTCCGCTCTGCGAAACAATGTTTTGCAAAACG
ACGACTGAGTGTAGCATCCG

Downstream 100 bases:

>100_bases
ATATTCTCAGGCCGTCCGATTCTCGTGCACGACGAATAGCGGCCCTTGTACGAATCGCACGTCGTACTGCTGCAGAAGAT
CGAACTGCGCTTCAGTTGCC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSKPASTTSPSPVTSLSTRTSDPVDERKFVVALARGLDLLRAFRPGETLLGNRDFVERTGLPKATVNRLAYTLTVLGYLR
FDEALGKYALDAGVLSLGFALLSGTDTLELARPHMRNFAREVGAAVSLGCRDGLDMIYLETIRSETALTLGLASGSKLSM
LTSSMGRAYLAVQPADTRAALLDELRRAAGDEGALLVAQAQREIDRYASEGCCYSFRDWHDDVNAVAVPFSDPRDGRLLV
LSCSGPASSMGESVFRERVAPRLKALARRLGDSP

Sequences:

>Translated_274_residues
MSKPASTTSPSPVTSLSTRTSDPVDERKFVVALARGLDLLRAFRPGETLLGNRDFVERTGLPKATVNRLAYTLTVLGYLR
FDEALGKYALDAGVLSLGFALLSGTDTLELARPHMRNFAREVGAAVSLGCRDGLDMIYLETIRSETALTLGLASGSKLSM
LTSSMGRAYLAVQPADTRAALLDELRRAAGDEGALLVAQAQREIDRYASEGCCYSFRDWHDDVNAVAVPFSDPRDGRLLV
LSCSGPASSMGESVFRERVAPRLKALARRLGDSP
>Mature_273_residues
SKPASTTSPSPVTSLSTRTSDPVDERKFVVALARGLDLLRAFRPGETLLGNRDFVERTGLPKATVNRLAYTLTVLGYLRF
DEALGKYALDAGVLSLGFALLSGTDTLELARPHMRNFAREVGAAVSLGCRDGLDMIYLETIRSETALTLGLASGSKLSML
TSSMGRAYLAVQPADTRAALLDELRRAAGDEGALLVAQAQREIDRYASEGCCYSFRDWHDDVNAVAVPFSDPRDGRLLVL
SCSGPASSMGESVFRERVAPRLKALARRLGDSP

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=240, Percent_Identity=25.8333333333333, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29532; Mature: 29401

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPASTTSPSPVTSLSTRTSDPVDERKFVVALARGLDLLRAFRPGETLLGNRDFVERTG
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHCC
LPKATVNRLAYTLTVLGYLRFDEALGKYALDAGVLSLGFALLSGTDTLELARPHMRNFAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
EVGAAVSLGCRDGLDMIYLETIRSETALTLGLASGSKLSMLTSSMGRAYLAVQPADTRAA
HHHHHHCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCEEEEECCCCHHHH
LLDELRRAAGDEGALLVAQAQREIDRYASEGCCYSFRDWHDDVNAVAVPFSDPRDGRLLV
HHHHHHHHCCCCCCEEHHHHHHHHHHHHCCCCEECHHHHCCCCCEEEECCCCCCCCEEEE
LSCSGPASSMGESVFRERVAPRLKALARRLGDSP
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKPASTTSPSPVTSLSTRTSDPVDERKFVVALARGLDLLRAFRPGETLLGNRDFVERTG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHCC
LPKATVNRLAYTLTVLGYLRFDEALGKYALDAGVLSLGFALLSGTDTLELARPHMRNFAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
EVGAAVSLGCRDGLDMIYLETIRSETALTLGLASGSKLSMLTSSMGRAYLAVQPADTRAA
HHHHHHCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCEEEEECCCCHHHH
LLDELRRAAGDEGALLVAQAQREIDRYASEGCCYSFRDWHDDVNAVAVPFSDPRDGRLLV
HHHHHHHHCCCCCCEEHHHHHHHHHHHHCCCCEECHHHHCCCCCEEEECCCCCCCCEEEE
LSCSGPASSMGESVFRERVAPRLKALARRLGDSP
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]