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The map label for this gene is caiD [C]

Identifier: 186477180

GI number: 186477180

Start: 2733033

End: 2733911

Strand: Direct

Name: caiD [C]

Synonym: Bphy_2431

Alternate gene names: 186477180

Gene position: 2733033-2733911 (Clockwise)

Preceding gene: 186477178

Following gene: 186477181

Centisome position: 78.55

GC content: 67.12

Gene sequence:

>879_bases
ATGTCCAGCGAACCATTCGGTGAACATGTGCGGATCGAAACTGCACAAAATTCCCCAACTGCACAGAATCAGCAAGTTGC
GCGCCCGCTCGATGCCGTCGCGACGATCGTCATCGACCGTTCCGAGCGCCGCAATGCCGTCGACCGTCCAACGGCGGAAG
CGCTGTCCGCCGCCTTCCGCCGCTTCGAAGCGAACGAAGCATGGCGCGTCGCGGTGCTGACGGGAGCGGGTGGCACGTTC
TGCGCGGGCGCGGACCTCACTGCTCTACAAGACGACGCGCGGCGCAACGAATTGCACGCCGACGGCAGCGGCCCCGGGCC
GATGGGGCCCACGCGCATGATGTTCGCGAAGCCGGTGATCGCCGCGATTGCGGGCCATGCGGTGGCGGGCGGTCTGGAAC
TGGCGGCGATGTGCGATCTGCGCGTGATCGAAGAAGACGCCGTGCTCGGCGTGTTCTGCCGACGCGTGGGCATTCCGCTG
ATCGACGGCGGCACGATCCGGCTGCCGCGCCTTATCGGGCAATCGCGCGCGCTGGATTTGATCTTGACGGGCCGTGCGCT
GACGGCCGACGAAGCGCTCGCGTTCGGCCTTGCGAATCGCGTCGTGCCGAAAGGTCATGCGCGCGCCGCCGCCGAGCAGC
TCGCGGCGGACCTGGCTGCGTTTCCGCAGGCGGCAGTGCTCGCGGACCGCCGCTCCGTCTACGAGAATTCGCCACTCGAC
AATCTGCAAGAAGCCCTGCGCCGCGAGGGCGCAGGTGGCTATGAGGCCGTGTTCGCGCAAGGGCTGACGGGCGCAGCTGC
ATTCGCTGCGGGTGCAGGCCGCCACGGCAGTGCGATCGGGCATGGCGAGAATCACACGTCAGACAAAAAAGTCCGTTGA

Upstream 100 bases:

>100_bases
TTGCGCGCTTCTTTAGGGTGTCGGCATGCGCGCAGCCGCTTTTACACGATGCTTTTCATTCCGTGCAGGTTTTTGCGAAA
GCTTCTCAACGGAGCGAACG

Downstream 100 bases:

>100_bases
AATAAGGGCCTTTCGCTGCGAAACGCACCCGCATCGACGAAATACAACAGTGCGCAACGCAGACTGCACGGCCAATATGG
CTTAGGTACAATCCCCTACT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSSEPFGEHVRIETAQNSPTAQNQQVARPLDAVATIVIDRSERRNAVDRPTAEALSAAFRRFEANEAWRVAVLTGAGGTF
CAGADLTALQDDARRNELHADGSGPGPMGPTRMMFAKPVIAAIAGHAVAGGLELAAMCDLRVIEEDAVLGVFCRRVGIPL
IDGGTIRLPRLIGQSRALDLILTGRALTADEALAFGLANRVVPKGHARAAAEQLAADLAAFPQAAVLADRRSVYENSPLD
NLQEALRREGAGGYEAVFAQGLTGAAAFAAGAGRHGSAIGHGENHTSDKKVR

Sequences:

>Translated_292_residues
MSSEPFGEHVRIETAQNSPTAQNQQVARPLDAVATIVIDRSERRNAVDRPTAEALSAAFRRFEANEAWRVAVLTGAGGTF
CAGADLTALQDDARRNELHADGSGPGPMGPTRMMFAKPVIAAIAGHAVAGGLELAAMCDLRVIEEDAVLGVFCRRVGIPL
IDGGTIRLPRLIGQSRALDLILTGRALTADEALAFGLANRVVPKGHARAAAEQLAADLAAFPQAAVLADRRSVYENSPLD
NLQEALRREGAGGYEAVFAQGLTGAAAFAAGAGRHGSAIGHGENHTSDKKVR
>Mature_291_residues
SSEPFGEHVRIETAQNSPTAQNQQVARPLDAVATIVIDRSERRNAVDRPTAEALSAAFRRFEANEAWRVAVLTGAGGTFC
AGADLTALQDDARRNELHADGSGPGPMGPTRMMFAKPVIAAIAGHAVAGGLELAAMCDLRVIEEDAVLGVFCRRVGIPLI
DGGTIRLPRLIGQSRALDLILTGRALTADEALAFGLANRVVPKGHARAAAEQLAADLAAFPQAAVLADRRSVYENSPLDN
LQEALRREGAGGYEAVFAQGLTGAAAFAAGAGRHGSAIGHGENHTSDKKVR

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=209, Percent_Identity=31.5789473684211, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI70995211, Length=186, Percent_Identity=32.258064516129, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI31542718, Length=225, Percent_Identity=26.2222222222222, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI68989263, Length=193, Percent_Identity=32.6424870466321, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI20127408, Length=174, Percent_Identity=32.183908045977, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4502327, Length=203, Percent_Identity=33.9901477832512, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI221307494, Length=208, Percent_Identity=25.4807692307692, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI4757968, Length=253, Percent_Identity=24.5059288537549, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI49355787, Length=253, Percent_Identity=24.5059288537549, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI221136756, Length=252, Percent_Identity=24.2063492063492, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI221136753, Length=252, Percent_Identity=24.2063492063492, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI221142681, Length=219, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788682, Length=190, Percent_Identity=37.3684210526316, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787659, Length=263, Percent_Identity=30.4182509505703, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788597, Length=200, Percent_Identity=30, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787660, Length=202, Percent_Identity=32.1782178217822, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790281, Length=178, Percent_Identity=29.2134831460674, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560910, Length=250, Percent_Identity=46.4, Blast_Score=194, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI25145438, Length=237, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17534483, Length=191, Percent_Identity=31.9371727748691, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17558304, Length=177, Percent_Identity=30.5084745762712, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17554946, Length=218, Percent_Identity=31.651376146789, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17540714, Length=177, Percent_Identity=30.5084745762712, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25144276, Length=201, Percent_Identity=28.8557213930348, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=201, Percent_Identity=28.8557213930348, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508951, Length=201, Percent_Identity=28.8557213930348, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536985, Length=218, Percent_Identity=28.8990825688073, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357171, Length=207, Percent_Identity=51.207729468599, Blast_Score=203, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24650670, Length=209, Percent_Identity=47.8468899521531, Blast_Score=191, Evalue=7e-49,
Organism=Drosophila melanogaster, GI20129971, Length=221, Percent_Identity=31.2217194570136, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24653477, Length=221, Percent_Identity=31.2217194570136, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24653139, Length=188, Percent_Identity=32.9787234042553, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI19921000, Length=213, Percent_Identity=30.5164319248826, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583077, Length=206, Percent_Identity=31.0679611650485, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24583079, Length=206, Percent_Identity=31.0679611650485, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 30542; Mature: 30411

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEPFGEHVRIETAQNSPTAQNQQVARPLDAVATIVIDRSERRNAVDRPTAEALSAAFR
CCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHEECCHHHCCCCCCCHHHHHHHHHH
RFEANEAWRVAVLTGAGGTFCAGADLTALQDDARRNELHADGSGPGPMGPTRMMFAKPVI
HHCCCCCEEEEEEECCCCCEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
AAIAGHAVAGGLELAAMCDLRVIEEDAVLGVFCRRVGIPLIDGGTIRLPRLIGQSRALDL
HHHHHHHHHCCHHHHHHHCEEEECHHHHHHHHHHHHCCCEECCCCEEHHHHHCCCCCEEE
ILTGRALTADEALAFGLANRVVPKGHARAAAEQLAADLAAFPQAAVLADRRSVYENSPLD
EEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHH
NLQEALRREGAGGYEAVFAQGLTGAAAFAAGAGRHGSAIGHGENHTSDKKVR
HHHHHHHHCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSEPFGEHVRIETAQNSPTAQNQQVARPLDAVATIVIDRSERRNAVDRPTAEALSAAFR
CCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHEECCHHHCCCCCCCHHHHHHHHHH
RFEANEAWRVAVLTGAGGTFCAGADLTALQDDARRNELHADGSGPGPMGPTRMMFAKPVI
HHCCCCCEEEEEEECCCCCEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
AAIAGHAVAGGLELAAMCDLRVIEEDAVLGVFCRRVGIPLIDGGTIRLPRLIGQSRALDL
HHHHHHHHHCCHHHHHHHCEEEECHHHHHHHHHHHHCCCEECCCCEEHHHHHCCCCCEEE
ILTGRALTADEALAFGLANRVVPKGHARAAAEQLAADLAAFPQAAVLADRRSVYENSPLD
EEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHH
NLQEALRREGAGGYEAVFAQGLTGAAAFAAGAGRHGSAIGHGENHTSDKKVR
HHHHHHHHCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA