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The map label for this gene is cutS [H]

Identifier: 186477173

GI number: 186477173

Start: 2724266

End: 2725783

Strand: Reverse

Name: cutS [H]

Synonym: Bphy_2422

Alternate gene names: 186477173

Gene position: 2725783-2724266 (Counterclockwise)

Preceding gene: 186477175

Following gene: 186477172

Centisome position: 78.35

GC content: 65.09

Gene sequence:

>1518_bases
ATGAGCCAGCCGATTCGCTTCTATCACCGCAACGCGATCCGTGAAATCACCGACGCGCCTGTGACCCGCACCGTTCTTCA
ATATCTGCGCGAGGACGCGCGCTGCACGGGCACCAAGGAAGGCTGCGCGGAAGGCGATTGCGGCGCGTGCACGGTCGTGA
TCGGTGAGCGCAACGACGCGGGCGGCATCAGCTTCAAGGCCGTCAACGCGTGCATCCAGTTCCTGCCGACGCTCGATGGC
AAGGCGCTCTTTACCGTCGAAGACCTGCGCCAGCCGGACGGCAGTCTGCATCCCGTGCAGGAAGCGATGGTCGAATGTCA
CGGCTCGCAATGCGGCTTCTGCACGCCGGGCTTCGTGATGTCGATGTGGTCGATCTATGAAAGGCACGGACATGAGCACA
GCTGCGCAAACAAAACGGTTCCCAATCGCGCGGATATCGCCAATGCGCTGACAGGCAATCTGTGCCGTTGCACCGGCTAT
CGCCCGATCATCGACGCGGCCGAGCGCATGTTCCAGTTGGCCGCACCGAAAGCGCCCATCGATGTCAAGTCGCTCGCGCA
GAAGCTTGCGACGCTCGAACGCGGCGAAACCTTCCACTACGAACACGACGGGCAGCAGTTCGACGCGCCACGCACCGTCG
GGGCGCTCGCGCAGATCAAGGCGGCCGCACCCGACACGCGGATTCTCGCGGGCAGCACCGATATCGGCCTGTGGGTCACA
AAGATGATGCGCGACCTGGGCCATATCGTGTACGTCGGCCAGATCGCCGAGATGCAGAAGATCGGCGTCACCGACGACTG
GATCGAAATCGGCGCCGCTGTCACCGTCGAGCGGGCGTATGCCGAACTCGCGAAGCAGTATCCCGAGCTGACCGAGATGT
GGCAGCGCTTTGCGTCGCTGCCCATTCGCAACGCCGGCACGCTCGGCGGCAACGTGGCGAACGGCTCGCCCATCGGCGAT
TCGATGCCGGGCCTGATCGCGCTGGGCGCGCGTGTCGTGCTGCGCGGCGGCGACATCGAACGCGAACTGCCGCTGGAAGA
CCTGTACCTCGCGTATCAGAAGAAGGACATGGCCGCGCACGAGTTCGTCGTCGGTCTGAAGGTGCCCGCGCGCAACGCGG
CGCGCCAGCACTTCCAGTTCCGCACGTACAAGATTTCGAAGCGCTTCGACTCGGATATTTCCGCCGTGTGCGCCGCGTTC
TCGTTCATCGCGGATGGCGAGACCATTCGCGAGCCGCGCATCGCGTTCGGCGGGATGGCCGCGACCCCGAAGCGCGCGAC
GCACGCGGAAGCCGCGCTCGCCGACAACGACTGGCACGAAGCGACCGCGCGGATCGCGATGCTCGCGCTCGCGAAAGACT
ATGAGCCGCTGTCCGACATGCGCGCCACCAGCGACTACCGCCTCGAAGCCGCGAAGAACACGCTGTACCGCTTCTGGCTC
GAAACACGCCCGAACGATCCGCTGCAAAAGAGTGCGCTCGATGTGCGCGCGGTGCTGGCGGCAGGCGCGGACGCCTGA

Upstream 100 bases:

>100_bases
GGGCCTATGGGTTGTGAATATTGATGATGCTACTTTTCGACCATCAGCCGCACCGTCCGCCGTCCGGCGCGGACGCGAAC
AACCGAAACGAGCACGAGAC

Downstream 100 bases:

>100_bases
TAGCGAAGGGTACGAATACGGAGAACCTGCAGAATGAACCAGCAAGCCGAACCGTTCCTGAAAGACGCGAAGGAACTCGC
CGACTTCACGCAAGTGCACG

Product: xanthine dehydrogenase small subunit

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MSQPIRFYHRNAIREITDAPVTRTVLQYLREDARCTGTKEGCAEGDCGACTVVIGERNDAGGISFKAVNACIQFLPTLDG
KALFTVEDLRQPDGSLHPVQEAMVECHGSQCGFCTPGFVMSMWSIYERHGHEHSCANKTVPNRADIANALTGNLCRCTGY
RPIIDAAERMFQLAAPKAPIDVKSLAQKLATLERGETFHYEHDGQQFDAPRTVGALAQIKAAAPDTRILAGSTDIGLWVT
KMMRDLGHIVYVGQIAEMQKIGVTDDWIEIGAAVTVERAYAELAKQYPELTEMWQRFASLPIRNAGTLGGNVANGSPIGD
SMPGLIALGARVVLRGGDIERELPLEDLYLAYQKKDMAAHEFVVGLKVPARNAARQHFQFRTYKISKRFDSDISAVCAAF
SFIADGETIREPRIAFGGMAATPKRATHAEAALADNDWHEATARIAMLALAKDYEPLSDMRATSDYRLEAAKNTLYRFWL
ETRPNDPLQKSALDVRAVLAAGADA

Sequences:

>Translated_505_residues
MSQPIRFYHRNAIREITDAPVTRTVLQYLREDARCTGTKEGCAEGDCGACTVVIGERNDAGGISFKAVNACIQFLPTLDG
KALFTVEDLRQPDGSLHPVQEAMVECHGSQCGFCTPGFVMSMWSIYERHGHEHSCANKTVPNRADIANALTGNLCRCTGY
RPIIDAAERMFQLAAPKAPIDVKSLAQKLATLERGETFHYEHDGQQFDAPRTVGALAQIKAAAPDTRILAGSTDIGLWVT
KMMRDLGHIVYVGQIAEMQKIGVTDDWIEIGAAVTVERAYAELAKQYPELTEMWQRFASLPIRNAGTLGGNVANGSPIGD
SMPGLIALGARVVLRGGDIERELPLEDLYLAYQKKDMAAHEFVVGLKVPARNAARQHFQFRTYKISKRFDSDISAVCAAF
SFIADGETIREPRIAFGGMAATPKRATHAEAALADNDWHEATARIAMLALAKDYEPLSDMRATSDYRLEAAKNTLYRFWL
ETRPNDPLQKSALDVRAVLAAGADA
>Mature_504_residues
SQPIRFYHRNAIREITDAPVTRTVLQYLREDARCTGTKEGCAEGDCGACTVVIGERNDAGGISFKAVNACIQFLPTLDGK
ALFTVEDLRQPDGSLHPVQEAMVECHGSQCGFCTPGFVMSMWSIYERHGHEHSCANKTVPNRADIANALTGNLCRCTGYR
PIIDAAERMFQLAAPKAPIDVKSLAQKLATLERGETFHYEHDGQQFDAPRTVGALAQIKAAAPDTRILAGSTDIGLWVTK
MMRDLGHIVYVGQIAEMQKIGVTDDWIEIGAAVTVERAYAELAKQYPELTEMWQRFASLPIRNAGTLGGNVANGSPIGDS
MPGLIALGARVVLRGGDIERELPLEDLYLAYQKKDMAAHEFVVGLKVPARNAARQHFQFRTYKISKRFDSDISAVCAAFS
FIADGETIREPRIAFGGMAATPKRATHAEAALADNDWHEATARIAMLALAKDYEPLSDMRATSDYRLEAAKNTLYRFWLE
TRPNDPLQKSALDVRAVLAAGADA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG4630

COG function: function code F; Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=512, Percent_Identity=27.9296875, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI71773480, Length=537, Percent_Identity=26.6294227188082, Blast_Score=139, Evalue=5e-33,
Organism=Escherichia coli, GI1789231, Length=250, Percent_Identity=27.6, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786480, Length=158, Percent_Identity=32.2784810126582, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789232, Length=139, Percent_Identity=32.3741007194245, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17540638, Length=161, Percent_Identity=44.0993788819876, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17539860, Length=144, Percent_Identity=42.3611111111111, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI32566215, Length=144, Percent_Identity=42.3611111111111, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI17737937, Length=498, Percent_Identity=30.7228915662651, Blast_Score=209, Evalue=5e-54,
Organism=Drosophila melanogaster, GI24647201, Length=504, Percent_Identity=27.3809523809524, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24647199, Length=501, Percent_Identity=28.3433133732535, Blast_Score=170, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24647197, Length=502, Percent_Identity=27.6892430278884, Blast_Score=168, Evalue=9e-42,
Organism=Drosophila melanogaster, GI24647195, Length=319, Percent_Identity=31.6614420062696, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24647193, Length=503, Percent_Identity=28.0318091451292, Blast_Score=156, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 55338; Mature: 55206

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00197 2FE2S_FER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPIRFYHRNAIREITDAPVTRTVLQYLREDARCTGTKEGCAEGDCGACTVVIGERNDA
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCC
GGISFKAVNACIQFLPTLDGKALFTVEDLRQPDGSLHPVQEAMVECHGSQCGFCTPGFVM
CCCHHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHH
SMWSIYERHGHEHSCANKTVPNRADIANALTGNLCRCTGYRPIIDAAERMFQLAAPKAPI
HHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCCCCCC
DVKSLAQKLATLERGETFHYEHDGQQFDAPRTVGALAQIKAAAPDTRILAGSTDIGLWVT
CHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHH
KMMRDLGHIVYVGQIAEMQKIGVTDDWIEIGAAVTVERAYAELAKQYPELTEMWQRFASL
HHHHHHCCEEEEHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHCHHHHHHHHHHHCC
PIRNAGTLGGNVANGSPIGDSMPGLIALGARVVLRGGDIERELPLEDLYLAYQKKDMAAH
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
EFVVGLKVPARNAARQHFQFRTYKISKRFDSDISAVCAAFSFIADGETIREPRIAFGGMA
HEEEEEECCCCHHHHHHHHHHEEEHHHHHCCHHHHHHHHHHHHCCCCHHCCCCHHCCCCC
ATPKRATHAEAALADNDWHEATARIAMLALAKDYEPLSDMRATSDYRLEAAKNTLYRFWL
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHEEEE
ETRPNDPLQKSALDVRAVLAAGADA
CCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SQPIRFYHRNAIREITDAPVTRTVLQYLREDARCTGTKEGCAEGDCGACTVVIGERNDA
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCC
GGISFKAVNACIQFLPTLDGKALFTVEDLRQPDGSLHPVQEAMVECHGSQCGFCTPGFVM
CCCHHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHH
SMWSIYERHGHEHSCANKTVPNRADIANALTGNLCRCTGYRPIIDAAERMFQLAAPKAPI
HHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCCCCCC
DVKSLAQKLATLERGETFHYEHDGQQFDAPRTVGALAQIKAAAPDTRILAGSTDIGLWVT
CHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHH
KMMRDLGHIVYVGQIAEMQKIGVTDDWIEIGAAVTVERAYAELAKQYPELTEMWQRFASL
HHHHHHCCEEEEHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHCHHHHHHHHHHHCC
PIRNAGTLGGNVANGSPIGDSMPGLIALGARVVLRGGDIERELPLEDLYLAYQKKDMAAH
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
EFVVGLKVPARNAARQHFQFRTYKISKRFDSDISAVCAAFSFIADGETIREPRIAFGGMA
HEEEEEECCCCHHHHHHHHHHEEEHHHHHCCHHHHHHHHHHHHCCCCHHCCCCHHCCCCC
ATPKRATHAEAALADNDWHEATARIAMLALAKDYEPLSDMRATSDYRLEAAKNTLYRFWL
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHEEEE
ETRPNDPLQKSALDVRAVLAAGADA
CCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]