Click here to switch to the map view.

The map label for this gene is 186477175

Identifier: 186477175

GI number: 186477175

Start: 2727590

End: 2728810

Strand: Reverse

Name: 186477175

Synonym: Bphy_2424

Alternate gene names: NA

Gene position: 2728810-2727590 (Counterclockwise)

Preceding gene: 186477176

Following gene: 186477173

Centisome position: 78.43

GC content: 64.13

Gene sequence:

>1221_bases
ATGACCATTACAACGTCCAACGTCGTTCCCTGTCCTGAAGTCGAATCGCTCGATGCGATTCTTCCCGAAGAACCGCTGCT
GATGATGGGCGCCGGCCCCGTGCCGATCCCCGCCGCGGTCGCGAAGGCCAATGCGATCGTCATCAACCATCTGGGCAATA
CGATGGCCAAGGTGGTCGGACAGGTGAAGACGATGGCGCGCTACGTGTTTCAGACGAATTCGAAGTGGGTACTGGGCGTC
GCGGGTCCGGGCTCGGCCGCCATGGAGATGGCGATTTCCAATCTCGCGTGGCGTGGCACGCGCGTGCTGAGCATCAAGAA
CGGCTTTTTCAGCGCGCGGATGGCGGAGATGGGGCGGCGCGTCGGTGCGGACGTGACGCTGCTCGAAGTCGAGGACCGGG
CGGTCGCCACGCTCGAACAGGTCGAAGAAGCGATTCGCCGCACGCGTCCCGAGATCGTGACGATCGTGCAGGGCGAGACG
TCGAATACCGTCTGGAACTACCACCTGCAAGACATCGCTGCGCTCGCGAAGAAGGCGGGGGCGCTCGTCGTCGTGGATGC
CGTGTGCACGTTGTCGACGATGCCGCTCGACATGGATGCCTGGGGCATCGACGCGGTGATCACGGGCGGGCAGAAGGGGT
TGTCGTCGATTCCCGGCGTGTCGCTGATCGCGTTTTCGGATGCGGCGTGGGAGCGGGTGAAGGGGCGCAAGGATGCGAGC
CCGCACTGGTGCCTCGACGCGGCGCTGGCGGAGAACTTCTGGCACAACGCGGGATATCACTATACGGCGCCCGTGTCGGG
TGTGCTGGCGCTGCACGAGGCGTTGCGGCTCGTGTGCGCGGAGACGCTGGAAAAGCGCTTCGCGCGGCATCTGAGGTGCT
CGCTTGCGTTGCAGGCGGGGATCAGCGCAATGGGCTTGCAGCTGTATGCACCTGCCGAGTGCCGCTTGAATTCGGTGGTG
GGGATCGAGGTCCCTGTGAAGTCATCGCTGACGCCTGCTGATATCTGCGGACATATCTCCCGGTATCACCAGGTGGAGAT
TTCGGGATCGTTCGGGCTGCCGATCGTGCGGATCGGGCAGATGGGGGAGCAGGCGCGCGCGCATAACCTGTTTCGCACGC
TACATGCGTTTGGGCGGACGATGTCTGAGCTTGATGTTCGGGTGGATTTGCCGGCTGGGGTGGCAGCACTTGAGCGCGCG
CTGGCGGCGGGCAGGGAGTGA

Upstream 100 bases:

>100_bases
ATGGGTGAATGATCGAACGACGGCCCGCCGCCCGCAGGTGCTGCTGCGCGCGGCGGGCCTTTTTTCTGCAACGTTCACTT
CCGTTTCATGCGTATCGATC

Downstream 100 bases:

>100_bases
TTTTTTGTTGTGCCTGCGACGTAGTCGCCAGGTTTGCTTTCGCTGGGACGAGGTTTTTGCGGCTGCGCGGGCATCCGCTT
TGTACATCTGGTTTGCCGGC

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MTITTSNVVPCPEVESLDAILPEEPLLMMGAGPVPIPAAVAKANAIVINHLGNTMAKVVGQVKTMARYVFQTNSKWVLGV
AGPGSAAMEMAISNLAWRGTRVLSIKNGFFSARMAEMGRRVGADVTLLEVEDRAVATLEQVEEAIRRTRPEIVTIVQGET
SNTVWNYHLQDIAALAKKAGALVVVDAVCTLSTMPLDMDAWGIDAVITGGQKGLSSIPGVSLIAFSDAAWERVKGRKDAS
PHWCLDAALAENFWHNAGYHYTAPVSGVLALHEALRLVCAETLEKRFARHLRCSLALQAGISAMGLQLYAPAECRLNSVV
GIEVPVKSSLTPADICGHISRYHQVEISGSFGLPIVRIGQMGEQARAHNLFRTLHAFGRTMSELDVRVDLPAGVAALERA
LAAGRE

Sequences:

>Translated_406_residues
MTITTSNVVPCPEVESLDAILPEEPLLMMGAGPVPIPAAVAKANAIVINHLGNTMAKVVGQVKTMARYVFQTNSKWVLGV
AGPGSAAMEMAISNLAWRGTRVLSIKNGFFSARMAEMGRRVGADVTLLEVEDRAVATLEQVEEAIRRTRPEIVTIVQGET
SNTVWNYHLQDIAALAKKAGALVVVDAVCTLSTMPLDMDAWGIDAVITGGQKGLSSIPGVSLIAFSDAAWERVKGRKDAS
PHWCLDAALAENFWHNAGYHYTAPVSGVLALHEALRLVCAETLEKRFARHLRCSLALQAGISAMGLQLYAPAECRLNSVV
GIEVPVKSSLTPADICGHISRYHQVEISGSFGLPIVRIGQMGEQARAHNLFRTLHAFGRTMSELDVRVDLPAGVAALERA
LAAGRE
>Mature_405_residues
TITTSNVVPCPEVESLDAILPEEPLLMMGAGPVPIPAAVAKANAIVINHLGNTMAKVVGQVKTMARYVFQTNSKWVLGVA
GPGSAAMEMAISNLAWRGTRVLSIKNGFFSARMAEMGRRVGADVTLLEVEDRAVATLEQVEEAIRRTRPEIVTIVQGETS
NTVWNYHLQDIAALAKKAGALVVVDAVCTLSTMPLDMDAWGIDAVITGGQKGLSSIPGVSLIAFSDAAWERVKGRKDASP
HWCLDAALAENFWHNAGYHYTAPVSGVLALHEALRLVCAETLEKRFARHLRCSLALQAGISAMGLQLYAPAECRLNSVVG
IEVPVKSSLTPADICGHISRYHQVEISGSFGLPIVRIGQMGEQARAHNLFRTLHAFGRTMSELDVRVDLPAGVAALERAL
AAGRE

Specific function: Unknown

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=361, Percent_Identity=31.5789473684211, Blast_Score=176, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17536281, Length=375, Percent_Identity=28.2666666666667, Blast_Score=158, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6321079, Length=372, Percent_Identity=26.0752688172043, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17530823, Length=393, Percent_Identity=30.5343511450382, Blast_Score=170, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: NA

Molecular weight: Translated: 43503; Mature: 43372

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITTSNVVPCPEVESLDAILPEEPLLMMGAGPVPIPAAVAKANAIVINHLGNTMAKVVG
CEEECCCCCCCCCCCCHHHHCCCCCEEEECCCCCCCCHHHHHCCEEEEEHHHHHHHHHHH
QVKTMARYVFQTNSKWVLGVAGPGSAAMEMAISNLAWRGTRVLSIKNGFFSARMAEMGRR
HHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHH
VGADVTLLEVEDRAVATLEQVEEAIRRTRPEIVTIVQGETSNTVWNYHLQDIAALAKKAG
CCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHCC
ALVVVDAVCTLSTMPLDMDAWGIDAVITGGQKGLSSIPGVSLIAFSDAAWERVKGRKDAS
CEEEEEHHHHHCCCCCCCCCCCCCEEEECCCCCHHCCCCCEEEEECHHHHHHHCCCCCCC
PHWCLDAALAENFWHNAGYHYTAPVSGVLALHEALRLVCAETLEKRFARHLRCSLALQAG
CCHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ISAMGLQLYAPAECRLNSVVGIEVPVKSSLTPADICGHISRYHQVEISGSFGLPIVRIGQ
HHHHCEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHEEEEECCCCCCCEEEECC
MGEQARAHNLFRTLHAFGRTMSELDVRVDLPAGVAALERALAAGRE
CCHHHHHHHHHHHHHHHHCCHHHCEEEEECCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
TITTSNVVPCPEVESLDAILPEEPLLMMGAGPVPIPAAVAKANAIVINHLGNTMAKVVG
EEECCCCCCCCCCCCHHHHCCCCCEEEECCCCCCCCHHHHHCCEEEEEHHHHHHHHHHH
QVKTMARYVFQTNSKWVLGVAGPGSAAMEMAISNLAWRGTRVLSIKNGFFSARMAEMGRR
HHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHH
VGADVTLLEVEDRAVATLEQVEEAIRRTRPEIVTIVQGETSNTVWNYHLQDIAALAKKAG
CCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHCC
ALVVVDAVCTLSTMPLDMDAWGIDAVITGGQKGLSSIPGVSLIAFSDAAWERVKGRKDAS
CEEEEEHHHHHCCCCCCCCCCCCCEEEECCCCCHHCCCCCEEEEECHHHHHHHCCCCCCC
PHWCLDAALAENFWHNAGYHYTAPVSGVLALHEALRLVCAETLEKRFARHLRCSLALQAG
CCHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ISAMGLQLYAPAECRLNSVVGIEVPVKSSLTPADICGHISRYHQVEISGSFGLPIVRIGQ
HHHHCEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHEEEEECCCCCCCEEEECC
MGEQARAHNLFRTLHAFGRTMSELDVRVDLPAGVAALERALAAGRE
CCHHHHHHHHHHHHHHHHCCHHHCEEEEECCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]