| Definition | Burkholderia phymatum STM815 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010622 |
| Length | 3,479,187 |
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The map label for this gene is ykvO [H]
Identifier: 186477097
GI number: 186477097
Start: 2632839
End: 2633612
Strand: Reverse
Name: ykvO [H]
Synonym: Bphy_2346
Alternate gene names: 186477097
Gene position: 2633612-2632839 (Counterclockwise)
Preceding gene: 186477100
Following gene: 186477093
Centisome position: 75.7
GC content: 68.09
Gene sequence:
>774_bases ATGTCATTCGCGAACAAGACGGCGCTCATCACGGGCGGCAACGGAGGGATTGGTTTTGCGGCGGCGCGCCTGCTGATCGC ACAGGGCGCACGGGTGGCCATCACGGGCCGCGACCAGAAGAAGCTCGACGAAGCCGCGGCAGAACTCGGCCCGAGCGCAT TGCCGATCCGCGCCGACATCAACGACCCCGCCGCCATCGACGCCGTGATGAAAACGATCGCCGACACGTTCGGCAAGCTG GACATCGTGTTCGCGAATGCGGGGGTGAGCGGTGCGACGCCCGTCGGCGAGACGACGGCCGAGAAGTTCGAGGCGATCAT GCGCACCAACGTGACGTCCGTGTTCCTGACCGTGCAGGCGGCCGTGCCGCTGATGGGCGAGGGCGGCGCGATCGTGCTGA ACGGTTCGGTGATGCGTCAGTTGGGCGCGCCCGGCTCGTCGGCGTATTCGGCATCGAAGGCGGCCATTTCAGGCATGGCG CGCGTGCTCGCATCGGAGCTCGTCACGCGCGGCATCCGTGTGAACACGGTGATCCCGGGCGGCACCCGTACGTCGATCTG GACGCGCGGCGACCGCGAAGGCGCAACGCTCGATGCAACGGAAGCCGCGCTCAGCCCGATGATCCCGATGAACCGTTTCG CCCTCGCCGATGAAGTGGCGCAGGCCGCCGTGTTCCTCGCGTCGGATGCGGCGTCGGGCATGACGGCGGCTGAGATCGTC GTCGACGGCGGCAACACGGGTGCGCCGATGGGTGCGCCGGCGTTCCGCCGATAA
Upstream 100 bases:
>100_bases TGATTGCGATCACTATCATTAAATTAACATTGCAGTTGCAATTATAAGGCAGCTGTCGGCGGATGTCCGCCTCGAATCCT TAACTTTTGGAGAAGTCATC
Downstream 100 bases:
>100_bases GCGTCGGCAAGCGGCACAACGAAAAGGGCGACGCGCCATCGCGCATCGCTCTTCGGTTTTTCCAGCGTCTGGTGTTGCCG GGCGCGAACCGTCAGGCCAT
Product: short-chain dehydrogenase/reductase SDR
Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+
Alternate protein names: NA
Number of amino acids: Translated: 257; Mature: 256
Protein sequence:
>257_residues MSFANKTALITGGNGGIGFAAARLLIAQGARVAITGRDQKKLDEAAAELGPSALPIRADINDPAAIDAVMKTIADTFGKL DIVFANAGVSGATPVGETTAEKFEAIMRTNVTSVFLTVQAAVPLMGEGGAIVLNGSVMRQLGAPGSSAYSASKAAISGMA RVLASELVTRGIRVNTVIPGGTRTSIWTRGDREGATLDATEAALSPMIPMNRFALADEVAQAAVFLASDAASGMTAAEIV VDGGNTGAPMGAPAFRR
Sequences:
>Translated_257_residues MSFANKTALITGGNGGIGFAAARLLIAQGARVAITGRDQKKLDEAAAELGPSALPIRADINDPAAIDAVMKTIADTFGKL DIVFANAGVSGATPVGETTAEKFEAIMRTNVTSVFLTVQAAVPLMGEGGAIVLNGSVMRQLGAPGSSAYSASKAAISGMA RVLASELVTRGIRVNTVIPGGTRTSIWTRGDREGATLDATEAALSPMIPMNRFALADEVAQAAVFLASDAASGMTAAEIV VDGGNTGAPMGAPAFRR >Mature_256_residues SFANKTALITGGNGGIGFAAARLLIAQGARVAITGRDQKKLDEAAAELGPSALPIRADINDPAAIDAVMKTIADTFGKLD IVFANAGVSGATPVGETTAEKFEAIMRTNVTSVFLTVQAAVPLMGEGGAIVLNGSVMRQLGAPGSSAYSASKAAISGMAR VLASELVTRGIRVNTVIPGGTRTSIWTRGDREGATLDATEAALSPMIPMNRFALADEVAQAAVFLASDAASGMTAAEIVV DGGNTGAPMGAPAFRR
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=32.6446280991736, Blast_Score=114, Evalue=1e-25, Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=29.3650793650794, Blast_Score=110, Evalue=9e-25, Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=32.1428571428571, Blast_Score=110, Evalue=2e-24, Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=30.1204819277108, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=30.6772908366534, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI5031737, Length=261, Percent_Identity=30.6513409961686, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI66933014, Length=225, Percent_Identity=30.2222222222222, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=28.90625, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=34.3915343915344, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI126723191, Length=202, Percent_Identity=32.1782178217822, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI59889578, Length=229, Percent_Identity=30.5676855895196, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=27.4900398406374, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI31542939, Length=208, Percent_Identity=31.25, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI20149619, Length=219, Percent_Identity=29.6803652968037, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI157739938, Length=190, Percent_Identity=27.8947368421053, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4758504, Length=195, Percent_Identity=30.2564102564103, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI4503817, Length=194, Percent_Identity=28.8659793814433, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4503301, Length=251, Percent_Identity=28.6852589641434, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI109715829, Length=244, Percent_Identity=25.8196721311475, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI7706318, Length=189, Percent_Identity=26.984126984127, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI223718074, Length=197, Percent_Identity=28.4263959390863, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=35.3658536585366, Blast_Score=126, Evalue=2e-30, Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=36, Blast_Score=117, Evalue=1e-27, Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=38.6454183266932, Blast_Score=112, Evalue=3e-26, Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=32.9365079365079, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=31.9838056680162, Blast_Score=101, Evalue=4e-23, Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=32.5396825396825, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=30.8, Blast_Score=97, Evalue=8e-22, Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=30.9236947791165, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=29.6, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1787526, Length=191, Percent_Identity=32.4607329842932, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI2367365, Length=252, Percent_Identity=32.9365079365079, Blast_Score=88, Evalue=4e-19, Organism=Escherichia coli, GI1787820, Length=175, Percent_Identity=30.2857142857143, Blast_Score=82, Evalue=2e-17, Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=26.5625, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=30.1587301587302, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1786701, Length=184, Percent_Identity=32.6086956521739, Blast_Score=67, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=34.8484848484849, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=31.0344827586207, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI17560332, Length=274, Percent_Identity=32.1167883211679, Blast_Score=110, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=32.5925925925926, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=32.2834645669291, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=33.206106870229, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=33.8403041825095, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=31.8548387096774, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17538486, Length=274, Percent_Identity=30.6569343065693, Blast_Score=102, Evalue=3e-22, Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=32.5757575757576, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=32.6996197718631, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=30.6201550387597, Blast_Score=99, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17555706, Length=253, Percent_Identity=30.0395256916996, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=29.6442687747036, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=31.203007518797, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=29.7709923664122, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=30.8943089430894, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=29.6577946768061, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=31.9548872180451, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=29.5019157088123, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=27.6, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=30.7086614173228, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=29.6153846153846, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=27.9850746268657, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=28.3018867924528, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17538182, Length=195, Percent_Identity=34.8717948717949, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17536025, Length=264, Percent_Identity=31.4393939393939, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17536651, Length=263, Percent_Identity=28.8973384030418, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=27.8947368421053, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=28.2051282051282, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI71997402, Length=245, Percent_Identity=27.3469387755102, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17567345, Length=188, Percent_Identity=31.3829787234043, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17561272, Length=245, Percent_Identity=29.3877551020408, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17570069, Length=174, Percent_Identity=28.735632183908, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI71982365, Length=201, Percent_Identity=28.8557213930348, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=30, Blast_Score=99, Evalue=1e-21, Organism=Saccharomyces cerevisiae, GI6322067, Length=185, Percent_Identity=31.8918918918919, Blast_Score=78, Evalue=2e-15, Organism=Saccharomyces cerevisiae, GI6323882, Length=261, Percent_Identity=28.735632183908, Blast_Score=74, Evalue=3e-14, Organism=Saccharomyces cerevisiae, GI6322861, Length=193, Percent_Identity=26.4248704663212, Blast_Score=69, Evalue=8e-13, Organism=Saccharomyces cerevisiae, GI6322227, Length=192, Percent_Identity=29.1666666666667, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=34.8, Blast_Score=123, Evalue=1e-28, Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=34.6774193548387, Blast_Score=120, Evalue=1e-27, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=34.5381526104418, Blast_Score=117, Evalue=1e-26, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=34.8, Blast_Score=114, Evalue=5e-26, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=34.136546184739, Blast_Score=114, Evalue=7e-26, Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=30.7377049180328, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI17737361, Length=190, Percent_Identity=33.6842105263158, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=28.8537549407115, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI221331218, Length=202, Percent_Identity=34.6534653465347, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24665243, Length=202, Percent_Identity=34.6534653465347, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24644337, Length=250, Percent_Identity=31.2, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI221331216, Length=203, Percent_Identity=34.4827586206897, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24665247, Length=203, Percent_Identity=34.4827586206897, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI281364494, Length=201, Percent_Identity=29.3532338308458, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=29.5336787564767, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI28571387, Length=243, Percent_Identity=26.3374485596708, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI21356301, Length=196, Percent_Identity=27.0408163265306, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI116007236, Length=200, Percent_Identity=27, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100
Molecular weight: Translated: 25978; Mature: 25847
Theoretical pI: Translated: 5.36; Mature: 5.36
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.9 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.5 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSFANKTALITGGNGGIGFAAARLLIAQGARVAITGRDQKKLDEAAAELGPSALPIRADI CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCEEEEECC NDPAAIDAVMKTIADTFGKLDIVFANAGVSGATPVGETTAEKFEAIMRTNVTSVFLTVQA CCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHEEEEEEE AVPLMGEGGAIVLNGSVMRQLGAPGSSAYSASKAAISGMARVLASELVTRGIRVNTVIPG CCCEECCCCEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECC GTRTSIWTRGDREGATLDATEAALSPMIPMNRFALADEVAQAAVFLASDAASGMTAAEIV CCCCCEEECCCCCCCEECHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE VDGGNTGAPMGAPAFRR EECCCCCCCCCCCCCCC >Mature Secondary Structure SFANKTALITGGNGGIGFAAARLLIAQGARVAITGRDQKKLDEAAAELGPSALPIRADI CCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCEEEEECC NDPAAIDAVMKTIADTFGKLDIVFANAGVSGATPVGETTAEKFEAIMRTNVTSVFLTVQA CCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHEEEEEEE AVPLMGEGGAIVLNGSVMRQLGAPGSSAYSASKAAISGMARVLASELVTRGIRVNTVIPG CCCEECCCCEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECC GTRTSIWTRGDREGATLDATEAALSPMIPMNRFALADEVAQAAVFLASDAASGMTAAEIV CCCCCEEECCCCCCCEECHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE VDGGNTGAPMGAPAFRR EECCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+
Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]